Synthesis and characterization of a SIRT6 open tubular column: Predicting deacetylation activity using frontal chromatography

Analytical Biochemistry

Volumn 436, Issue 2, 2013, Pages 78-83

  Singh, Nagendra ^a   Ravichandran, Sarangan ^b   Norton, Darrell D ^a   Fugmann, Sebastian D ^a   Moaddel, Ruin ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

Frontal displacement chromatography; Histone deacetylation assay; Luteolin; Pharmacophore model

Indexed keywords

ACETYLATION; COLUMN CHROMATOGRAPHY; PHARMACODYNAMICS; PHENOLS;

CHROMATOGRAPHIC TECHNIQUES; DEACETYLATION; FRONTAL CHROMATOGRAPHY; FRONTAL DISPLACEMENT CHROMATOGRAPHIES; LUTEOLIN; OPEN TUBULAR CAPILLARIES; PHARMACOPHORE MODELING; SYNTHESIS AND CHARACTERIZATIONS;

FLAVONOIDS;

APIGENIN; FLAVONOID; KAEMPFEROL; LUTEOLIN; NARINGENIN; QUERCETIN; SIRTUIN 6; VITEXIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; BINDING SITE; DEACETYLATION; ENZYME ACTIVITY; FRONTAL AFFINITY CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN SYNTHESIS; SURFACE PROPERTY;

EID: 84874939431     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.01.018     Document Type: Article

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