Controlling enantioselectivity of esterase in asymmetric hydrolysis of aryl prochiral diesters by introducing aromatic interactions

Biotechnology and Bioengineering

Volumn 111, Issue 9, 2014, Pages 1729-1739

  Guo, Fei ^a   Franzen, Stefan ^a   Ye, Lidan ^a   Gu, Jiali ^a   Yu, Hongwei ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Aromatic interactions; Enantioselectivity; Esterase; Molecular dynamics simulation; Rational design

Indexed keywords

AROMATIC COMPOUNDS; AROMATIZATION; BINDING ENERGY; ENZYMES; ESCHERICHIA COLI; ESTERS; HYDROLYSIS; MOLECULAR DYNAMICS;

AROMATIC INTERACTIONS; ASYMMETRIC HYDROLYSIS; DIFFERENT SUBSTRATES; ENZYME ENANTIOSELECTIVITY; ESTERASE; MOLECULAR DYNAMICS SIMULATIONS; RATIONAL DESIGN; RHODOBACTER SPHAEROIDES;

ENANTIOSELECTIVITY;

AROMATIC COMPOUND; BIOH ESTERASE; ESTERASE; GLUTARIC ACID; RSPE ESTERASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL INTERACTION; ENANTIOSELECTIVITY; ENZYME ASSAY; ENZYME PURIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROLYSIS; MOLECULAR DYNAMICS; MUTANT; RHODOBACTER SPHAEROIDES; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM;

ESCHERICHIA COLI; RHODOBACTER SPHAEROIDES;

ESCHERICHIA COLI; ESTERASES; HYDROLYSIS; RHODOBACTER SPHAEROIDES; SUBSTRATE SPECIFICITY;

EID: 84905042707     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25249     Document Type: Article

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