Molecular Basis for the Enantioselective Ring Opening of β-Lactams Catalyzed by Candida antarctica Lipase B

Advanced Synthesis and Catalysis

Volumn 345, Issue 8, 2003, Pages 986-995

  Park, Seongsoon ^a   Forró, Enikö ^a,b   Grewal, Harjap ^a   Fülöp, Ferenc ^b   Kazlauskas, Romas J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

amino acids; lactam ring opening; Candida antarctica; Enantioselectivity; Enzyme catalysis; Lipase B; Molecular modeling

Indexed keywords

2 OCTANOL; 4 PHENYLAZETIDIN 2 ONE; ALCOHOL DERIVATIVE; AZETIDINE DERIVATIVE; BETA LACTAM DERIVATIVE; DIISOPROPYL ETHER; ETHER DERIVATIVE; HISTIDINE; LACTONE DERIVATIVE; LIPASE B; NITROGEN; UNCLASSIFIED DRUG; WATER;

ARTICLE; CANDIDA ANTARCTICA; CATALYSIS; COMPUTER MODEL; ENANTIOMER; ENANTIOSELECTIVITY; HYDROLYSIS; NONHUMAN; POLYMERIZATION; RING OPENING;

EID: 0242691679     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/adsc.200303069     Document Type: Article

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