Enzymatic Hydrolysis of a Prochiral 3-Substituted Glutarate Ester, an Intermediate in the Synthesis of an NK1/NK2 Dual Antagonist

Advanced Synthesis and Catalysis

Volumn 343, Issue 6-7, 2001, Pages 744-749

  Homann, Michael J ^a   Vail, Robert ^a   Morgan, Brian ^a,c   Sabesan, Vijay ^a   Levy, Cliff ^a   Dodds, David R ^a,b   Zaks, Aleksey ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b BRISTOL MYERS SQUIBB COMPANY   (United States)

^c DIVERSA CORPORATION   (United States)

Author keywords

Candida antarctica lipase; Enzymatic desymmetrization; Enzymatic hydrolysis; Prochiral selectivity

Indexed keywords

EID: 0013170373     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/1615-4169(200108)343:6/7<744::aid-adsc744>3.3.co;2-5     Document Type: Article

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