St John's Wort (Hypericum perforatum L.) photomedicine: Hypericin-photodynamic therapy induces metastatic melanoma cell death

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Kleemann, Britta ^a   Loos, Benjamin ^b   Scriba, Thomas J ^a   Lang, Dirk ^a   Davids, Lester M ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 8; HYPERICIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHOSPHATIDYLSERINE; APOPTOSIS REGULATORY PROTEIN; PERYLENE; PHOTOSENSITIZING AGENT;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DESTRUCTION; CELL KILLING; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL SIZE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYPERICUM PERFORATUM; IN VITRO STUDY; LYSOSOME; MELANOMA CELL; MELANOSOME; METASTATIC MELANOMA; MITOCHONDRION; PHOTODYNAMIC THERAPY; PIGMENTATION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; TISSUE CULTURE; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENETICS; HYPERICUM; MELANOMA; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOTOCHEMOTHERAPY; SKIN NEOPLASMS; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL SIZE; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOPLASMIC RETICULUM; FEMALE; HUMANS; HYPERICUM; MELANOMA; MIDDLE AGED; PERYLENE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PIGMENTATION; SKIN NEOPLASMS; TRANSCRIPTIONAL ACTIVATION;

EID: 84905017620     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103762     Document Type: Article

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