Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin

Journal of Photochemistry and Photobiology B: Biology

Volumn 93, Issue 2, 2008, Pages 108-118

  Kleban, Ján ^a   Mikeš, Jaromír ^a   Horváth, Viktor ^b   Sačková, Veronika ^a   Hofmanová, Jiřina ^b   Kozubík, Alois ^b   Fedoročko, Peter ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

^b INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

Hypericin; MK 886; ROS

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN E; HYDROGEN PEROXIDE; HYPERICIN; LAMIN B; LEUKOTRIENE B4; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; SUPEROXIDE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL STRAIN HT29; CELL SURVIVAL; CLONOGENESIS; COLON ADENOCARCINOMA; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME DEGRADATION; EXPERIMENTAL MODEL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

APOPTOSIS; CELL CYCLE; COLONIC NEOPLASMS; DRUG SYNERGISM; HT29 CELLS; HUMANS; INDOLES; LIPOXYGENASE INHIBITORS; PERYLENE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 54849431772     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2008.07.007     Document Type: Article

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