Enhanced antiproliferative and apoptotic response of HT-29 adenocarcinoma cells to combination of photoactivated hypericin and farnesyltransferase inhibitor manumycin A

International Journal of Molecular Sciences

Volumn 12, Issue 12, 2011, Pages 8388-8405

  Sačková, Veronika ^a   Kuliková, Lucia ^a   Kello, Martin ^a   Uhrinová, Ivana ^a   Fedoročko, Peter ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

Author keywords

Apoptosis; Farnesyltransferase; Hypericin; Manumycin

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 7; HYPERICIN; LAMIN B; MANUMYCIN A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOTOACTIVATED HYPERICIN; PROCASPASE 3; PROTEIN BAX; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAS PROTEIN; UNCLASSIFIED DRUG; AMIDE; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; MANUMYCIN; PERYLENE; POLYENE; RADIOSENSITIZING AGENT;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL NUCLEUS; CELL STRAIN HT29; CHEMICAL MODIFICATION; CLONOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; FARNESYLATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MONOTHERAPY; PHOTOACTIVATION; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; ADENOCARCINOMA; ANALOGS AND DERIVATIVES; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; HT 29 CELL LINE; METABOLISM;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 7; CELL PROLIFERATION; ENZYME INHIBITORS; HT29 CELLS; HUMANS; LAMIN TYPE B; PERYLENE; POLY(ADP-RIBOSE) POLYMERASES; POLYENES; POLYUNSATURATED ALKAMIDES; RADIATION-SENSITIZING AGENTS; RAS PROTEINS;

EID: 84055221871     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12128388     Document Type: Article

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