Parabens can enable hallmarks and characteristics of cancer in human breast epithelial cells: A review of the literature with reference to new exposure data and regulatory status

Journal of Applied Toxicology

Volumn 34, Issue 9, 2014, Pages 925-938

  Darbre, Philippa D ^a   Harvey, Philip W ^b  

^a UNIVERSITY OF READING   (United Kingdom)

^b Department of Genetic and Molecular Toxicology   (United Kingdom)

Author keywords

Breast cancer; Cosmetics; Endocrine disruption; Hallmarks of cancer; Oestrogen; Paraben; Personal care products

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; BENZYL PARABEN; BUTYL PARABEN; ESTRADIOL; ESTROGEN RELATED RECEPTOR GAMMA; ETHYL PARABEN; HYDROXYTAMOXIFEN; ISOBUTYL PARABEN; METHYL PARABEN; PROPYL PARABEN; PROTEIN; UNCLASSIFIED DRUG; ESRRG PROTEIN, HUMAN; ESTROGEN RECEPTOR; MTOR PROTEIN, HUMAN; TAMOXIFEN; TARGET OF RAPAMYCIN KINASE;

ABSORPTION; APOPTOSIS; BIOAVAILABILITY; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CANCER GROWTH; CANCER RISK; CELL DEATH; CELL IMMORTALIZATION; CELL INVASION; CELL PROLIFERATION; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; DNA DAMAGE; ENERGY METABOLISM; ESTROGEN ACTIVITY; GENOMIC INSTABILITY; HUMAN; LONG TERM EXPOSURE; MEDICAL LITERATURE; METASTASIS; MULTIPLE CANCER; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW; TOXICOKINETICS; TUMOR INVASION; TUMOR VASCULARIZATION; ANALOGS AND DERIVATIVES; BREAST; BREAST TUMOR; CYTOLOGY; DRUG EFFECTS; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; FEMALE; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; BIOLOGICAL AVAILABILITY; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; EPITHELIAL CELLS; FEMALE; GENOMIC INSTABILITY; HUMANS; PARABENS; RECEPTORS, ESTROGEN; TAMOXIFEN; TOR SERINE-THREONINE KINASES;

EID: 84904984812     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3027     Document Type: Review

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