-
2
-
-
0027996193
-
Menopausal estrogen and estrogen-progestin replacement therapy and risk of breast cancer (United States)
-
doi:10.1007/BF01831376
-
Schairer C, Byrne C, Keyl PM, Brinton LA, Sturgeon SR, Hoover RN. Menopausal estrogen and estrogen-progestin replacement therapy and risk of breast cancer (United States). Cancer Causes Control (1994) 5:491-500. doi:10.1007/BF01831376
-
(1994)
Cancer Causes Control
, vol.5
, pp. 491-500
-
-
Schairer, C.1
Byrne, C.2
Keyl, P.M.3
Brinton, L.A.4
Sturgeon, S.R.5
Hoover, R.N.6
-
3
-
-
78751591551
-
The contribution of postmenopausal hormone use cessation to the declining incidence of breast cancer
-
doi:10.1007/s10552-010-9682-7
-
Sprague BL, Trentham-Dietz A, Remington PL. The contribution of postmenopausal hormone use cessation to the declining incidence of breast cancer. Cancer Causes Control (2011) 22:125-34. doi:10.1007/s10552-010-9682-7
-
(2011)
Cancer Causes Control
, vol.22
, pp. 125-134
-
-
Sprague, B.L.1
Trentham-Dietz, A.2
Remington, P.L.3
-
4
-
-
84869083222
-
The benefits and harms of breast cancer screening: an independent review
-
Independent U.K Panel on Breast Cancer Screening. doi:10.1016/S0140-6736(12)61611-0
-
Independent UK Panel on Breast Cancer Screening. The benefits and harms of breast cancer screening: an independent review. Lancet (2012) 380:1778-86. doi:10.1016/S0140-6736(12)61611-0
-
(2012)
Lancet
, vol.380
, pp. 1778-1786
-
-
-
5
-
-
0034680102
-
Molecular portraits of human breast tumours
-
doi:10.1038/35021093
-
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, et al. Molecular portraits of human breast tumours. Nature (2000) 406:747-52. doi:10.1038/35021093
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
van de Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
-
6
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
doi:10.1073/pnas.191367098
-
Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A (2001) 98:10869-74. doi:10.1073/pnas.191367098
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
-
7
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
doi:10.1073/pnas.1732912100
-
Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, Jazaeri A, et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci U S A (2003) 100:10393-8. doi:10.1073/pnas.1732912100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
Korn, E.L.4
Long, P.M.5
Jazaeri, A.6
-
8
-
-
34548863946
-
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
doi:10.1186/gb-2007-8-5-r76
-
Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol (2007) 8:R76. doi:10.1186/gb-2007-8-5-r76
-
(2007)
Genome Biol
, vol.8
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
Mikaelian, I.4
Usary, J.5
Hu, Z.6
-
9
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
doi:10.1186/bcr2635
-
Prat A, Parker JS, Karginova O, Fan C, Livasy C, Herschkowitz JI, et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res (2010) 12:R68. doi:10.1186/bcr2635
-
(2010)
Breast Cancer Res
, vol.12
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
Fan, C.4
Livasy, C.5
Herschkowitz, J.I.6
-
10
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
doi:10.1172/JCI45014
-
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest (2011) 121:2750-67. doi:10.1172/JCI45014
-
(2011)
J Clin Invest
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
Sanders, M.E.4
Chakravarthy, A.B.5
Shyr, Y.6
-
11
-
-
84857605169
-
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials
-
doi:10.1016/S0140-6736(11)60993-8
-
Davies C, Godwin J, Gray R, Clarke M, Cutter D, Darby S, et al. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet (2011) 378:771-84. doi:10.1016/S0140-6736(11)60993-8
-
(2011)
Lancet
, vol.378
, pp. 771-784
-
-
Davies, C.1
Godwin, J.2
Gray, R.3
Clarke, M.4
Cutter, D.5
Darby, S.6
-
12
-
-
0037464769
-
Overview of the main outcomes in breast-cancer prevention trials
-
doi:10.1016/S0140-6736(03)12342-2
-
Cuzick J, Powles T, Veronesi U, Forbes J, Edwards R, Ashley S, et al. Overview of the main outcomes in breast-cancer prevention trials. Lancet (2003) 361:296-300. doi:10.1016/S0140-6736(03)12342-2
-
(2003)
Lancet
, vol.361
, pp. 296-300
-
-
Cuzick, J.1
Powles, T.2
Veronesi, U.3
Forbes, J.4
Edwards, R.5
Ashley, S.6
-
13
-
-
33847773775
-
Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial
-
doi:10.1093/jnci/djk050
-
Powles TJ, Ashley S, Tidy A, Smith IE, Dowsett M. Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial. J Natl Cancer Inst (2007) 99:283-90. doi:10.1093/jnci/djk050
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 283-290
-
-
Powles, T.J.1
Ashley, S.2
Tidy, A.3
Smith, I.E.4
Dowsett, M.5
-
14
-
-
27944492407
-
Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
-
doi:10.1093/jnci/dji372
-
Fisher B, Costantino JP, Wickerham DL, Cecchini RS, Cronin WM, Robidoux A, et al. Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst (2005) 97:1652-62. doi:10.1093/jnci/dji372
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1652-1662
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Cecchini, R.S.4
Cronin, W.M.5
Robidoux, A.6
-
15
-
-
34249732092
-
Tamoxifen for the prevention of breast cancer: late results of the Italian randomized tamoxifen prevention trial among women with hysterectomy
-
doi:10.1093/jnci/djk154
-
Veronesi U, Maisonneuve P, Rotmensz N, Bonanni B, Boyle P, Viale G, et al. Tamoxifen for the prevention of breast cancer: late results of the Italian randomized tamoxifen prevention trial among women with hysterectomy. J Natl Cancer Inst (2007) 99:727-37. doi:10.1093/jnci/djk154
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 727-737
-
-
Veronesi, U.1
Maisonneuve, P.2
Rotmensz, N.3
Bonanni, B.4
Boyle, P.5
Viale, G.6
-
16
-
-
33847793068
-
Long-term results of tamoxifen prophylaxis for breast cancer-96-month follow-up of the randomized IBIS-I trial
-
doi:10.1093/jnci/djk049
-
Cuzick J, Forbes JF, Sestak I, Cawthorn S, Hamed H, Holli K, et al. Long-term results of tamoxifen prophylaxis for breast cancer-96-month follow-up of the randomized IBIS-I trial. J Natl Cancer Inst (2007) 99:272-82. doi:10.1093/jnci/djk049
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 272-282
-
-
Cuzick, J.1
Forbes, J.F.2
Sestak, I.3
Cawthorn, S.4
Hamed, H.5
Holli, K.6
-
17
-
-
0033575083
-
The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple outcomes of raloxifene evaluation
-
Cummings SR, Eckert S, Krueger KA, Grady D, Powles TJ, Cauley JA, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple outcomes of raloxifene evaluation. JAMA (1999) 281:2189-97.
-
(1999)
JAMA
, vol.281
, pp. 2189-2197
-
-
Cummings, S.R.1
Eckert, S.2
Krueger, K.A.3
Grady, D.4
Powles, T.J.5
Cauley, J.A.6
-
18
-
-
10644283864
-
Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
-
doi:10.1093/jnci/djh319
-
Martino S, Cauley JA, Barrett-Connor E, Powles TJ, Mershon J, Disch D, et al. Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. J Natl Cancer Inst (2004) 96:1751-61. doi:10.1093/jnci/djh319
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1751-1761
-
-
Martino, S.1
Cauley, J.A.2
Barrett-Connor, E.3
Powles, T.J.4
Mershon, J.5
Disch, D.6
-
19
-
-
33745876266
-
Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women
-
doi:10.1056/NEJMoa062462
-
Barrett-Connor E, Mosca L, Collins P, Geiger MJ, Grady D, Kornitzer M, et al. Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women. N Engl J Med (2006) 355:125-37. doi:10.1056/NEJMoa062462
-
(2006)
N Engl J Med
, vol.355
, pp. 125-137
-
-
Barrett-Connor, E.1
Mosca, L.2
Collins, P.3
Geiger, M.J.4
Grady, D.5
Kornitzer, M.6
-
20
-
-
33745249570
-
Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
-
doi:10.1001/jama.295.23.joc60074
-
Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN, et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA (2006) 295:2727-41. doi:10.1001/jama.295.23.joc60074
-
(2006)
JAMA
, vol.295
, pp. 2727-2741
-
-
Vogel, V.G.1
Costantino, J.P.2
Wickerham, D.L.3
Cronin, W.M.4
Cecchini, R.S.5
Atkins, J.N.6
-
21
-
-
77349090257
-
Lasofoxifene in postmenopausal women with osteoporosis
-
doi:10.1056/NEJMoa0808692
-
Cummings SR, Ensrud K, Delmas PD, Lacroix AZ, Vukicevic S, Reid DM, et al. Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med (2010) 362:686-96. doi:10.1056/NEJMoa0808692
-
(2010)
N Engl J Med
, vol.362
, pp. 686-696
-
-
Cummings, S.R.1
Ensrud, K.2
Delmas, P.D.3
Lacroix, A.Z.4
Vukicevic, S.5
Reid, D.M.6
-
22
-
-
55249120962
-
IBIS II: a breast cancer prevention trial in postmenopausal women using the aromatase inhibitor anastrozole
-
doi:10.1586/14737140.8.9.1377
-
Cuzick J. IBIS II: a breast cancer prevention trial in postmenopausal women using the aromatase inhibitor anastrozole. Expert Rev Anticancer Ther (2008) 8:1377-85. doi:10.1586/14737140.8.9.1377
-
(2008)
Expert Rev Anticancer Ther
, vol.8
, pp. 1377-1385
-
-
Cuzick, J.1
-
23
-
-
38049037988
-
National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: evaluation of exemestane to prevent breast cancer in postmenopausal women
-
doi:10.3816/CBC.2007.n.057
-
Goss PE, Richardson H, Chlebowski R, Johnston D, Sarto GE, Maunsell E, et al. National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: evaluation of exemestane to prevent breast cancer in postmenopausal women. Clin Breast Cancer (2007) 7:895-900. doi:10.3816/CBC.2007.n.057
-
(2007)
Clin Breast Cancer
, vol.7
, pp. 895-900
-
-
Goss, P.E.1
Richardson, H.2
Chlebowski, R.3
Johnston, D.4
Sarto, G.E.5
Maunsell, E.6
-
24
-
-
79959403574
-
Exemestane for breast-cancer prevention in postmenopausal women
-
doi:10.1056/NEJMoa1103507
-
Goss PE, Ingle JN, Ales-Martinez JE, Cheung AM, Chlebowski RT, Wactawski-Wende J, et al. Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med (2011) 364:2381-91. doi:10.1056/NEJMoa1103507
-
(2011)
N Engl J Med
, vol.364
, pp. 2381-2391
-
-
Goss, P.E.1
Ingle, J.N.2
Ales-Martinez, J.E.3
Cheung, A.M.4
Chlebowski, R.T.5
Wactawski-Wende, J.6
-
25
-
-
78650711397
-
Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast
-
doi:10.1002/cncr.25399
-
Kuerer HM, Buzdar AU, Mittendorf EA, Esteva FJ, Lucci A, Vence LM, et al. Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast. Cancer (2011) 117:39-47. doi:10.1002/cncr.25399
-
(2011)
Cancer
, vol.117
, pp. 39-47
-
-
Kuerer, H.M.1
Buzdar, A.U.2
Mittendorf, E.A.3
Esteva, F.J.4
Lucci, A.5
Vence, L.M.6
-
26
-
-
80051495503
-
Lapatinib activity in premalignant lesions and T cancer of the breast in a randomized, placebo-controlled presurgical trial
-
doi:10.1158/1940-6207.CAPR-10-0337
-
Decensi A, Puntoni M, Pruneri G, Guerrieri-Gonzaga A, Lazzeroni M, Serrano D, et al. Lapatinib activity in premalignant lesions and T cancer of the breast in a randomized, placebo-controlled presurgical trial. Cancer Prev Res (Phila) (2011) 4:1181-9. doi:10.1158/1940-6207.CAPR-10-0337
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 1181-1189
-
-
Decensi, A.1
Puntoni, M.2
Pruneri, G.3
Guerrieri-Gonzaga, A.4
Lazzeroni, M.5
Serrano, D.6
-
27
-
-
84857750670
-
Abstract CN04-04: phase II trial of bexarotene in women at high risk of breast cancer: comparison of protein and RNA biomarkers
-
CN04-04. doi:10.1158/1940-6207.PREV-08-CN04-04
-
Brown P, Arun B, Miller A, Isaacs C, Gutierrez C, Huang J, et al. Abstract CN04-04: phase II trial of bexarotene in women at high risk of breast cancer: comparison of protein and RNA biomarkers. Cancer Prev Res (2008) 1:CN04-04. doi:10.1158/1940-6207.PREV-08-CN04-04
-
(2008)
Cancer Prev Res
, vol.1
-
-
Brown, P.1
Arun, B.2
Miller, A.3
Isaacs, C.4
Gutierrez, C.5
Huang, J.6
-
28
-
-
0024353118
-
A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer
-
doi:10.1038/bjc.1989.235
-
Powles TJ, Hardy JR, Ashley SE, Farrington GM, Cosgrove D, Davey JB, et al. A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer. Br J Cancer (1989) 60:126-31. doi:10.1038/bjc.1989.235
-
(1989)
Br J Cancer
, vol.60
, pp. 126-131
-
-
Powles, T.J.1
Hardy, J.R.2
Ashley, S.E.3
Farrington, G.M.4
Cosgrove, D.5
Davey, J.B.6
-
29
-
-
0032508294
-
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
-
doi:10.1016/S0140-6736(98)85012-5
-
Powles T, Eeles R, Ashley S, Easton D, Chang J, Dowsett M, et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet (1998) 352:98-101. doi:10.1016/S0140-6736(98)85012-5
-
(1998)
Lancet
, vol.352
, pp. 98-101
-
-
Powles, T.1
Eeles, R.2
Ashley, S.3
Easton, D.4
Chang, J.5
Dowsett, M.6
-
30
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
-
doi:10.1093/jnci/90.18.1371
-
Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst (1998) 90:1371-88. doi:10.1093/jnci/90.18.1371
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Redmond, C.K.4
Kavanah, M.5
Cronin, W.M.6
-
31
-
-
0032508293
-
Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study
-
doi:10.1016/S0140-6736(98)04394-3
-
Veronesi U, Maisonneuve P, Costa A, Sacchini V, Maltoni C, Robertson C, et al. Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study. Lancet (1998) 352:93-7. doi:10.1016/S0140-6736(98)04394-3
-
(1998)
Lancet
, vol.352
, pp. 93-97
-
-
Veronesi, U.1
Maisonneuve, P.2
Costa, A.3
Sacchini, V.4
Maltoni, C.5
Robertson, C.6
-
32
-
-
80052059849
-
First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial
-
doi:10.1016/S0140-6736(02)09962-2
-
Cuzick J, Forbes J, Edwards R, Baum M, Cawthorn S, Coates A, et al. First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial. Lancet (2002) 360:817-24. doi:10.1016/S0140-6736(02)09962-2
-
(2002)
Lancet
, vol.360
, pp. 817-824
-
-
Cuzick, J.1
Forbes, J.2
Edwards, R.3
Baum, M.4
Cawthorn, S.5
Coates, A.6
-
33
-
-
65649087426
-
Incidence of invasive breast cancer in postmenopausal women after discontinuation of long-term raloxifene administration
-
doi:10.3816/CBC.2009.n.008
-
Vogel VG, Qu Y, Wong M, Mitchell B, Mershon JL. Incidence of invasive breast cancer in postmenopausal women after discontinuation of long-term raloxifene administration. Clin Breast Cancer (2009) 9:45-50. doi:10.3816/CBC.2009.n.008
-
(2009)
Clin Breast Cancer
, vol.9
, pp. 45-50
-
-
Vogel, V.G.1
Qu, Y.2
Wong, M.3
Mitchell, B.4
Mershon, J.L.5
-
34
-
-
45849148006
-
Reduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk
-
doi:10.1093/jnci/djn153
-
Grady D, Cauley JA, Geiger MJ, Kornitzer M, Mosca L, Collins P, et al. Reduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk. J Natl Cancer Inst (2008) 100:854-61. doi:10.1093/jnci/djn153
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 854-861
-
-
Grady, D.1
Cauley, J.A.2
Geiger, M.J.3
Kornitzer, M.4
Mosca, L.5
Collins, P.6
-
35
-
-
77953529620
-
Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 trial: preventing breast cancer
-
doi:10.1158/1940-6207.CAPR-10-0076
-
Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN, et al. Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 trial: preventing breast cancer. Cancer Prev Res (Phila) (2010) 3:696-706. doi:10.1158/1940-6207.CAPR-10-0076
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 696-706
-
-
Vogel, V.G.1
Costantino, J.P.2
Wickerham, D.L.3
Cronin, W.M.4
Cecchini, R.S.5
Atkins, J.N.6
-
36
-
-
0141499607
-
The pharmacology of letrozole
-
doi:10.1016/S0960-0760(03)00384-4
-
Haynes BP, Dowsett M, Miller WR, Dixon JM, Bhatnagar AS. The pharmacology of letrozole. J Steroid Biochem Mol Biol (2003) 87:35-45. doi:10.1016/S0960-0760(03)00384-4
-
(2003)
J Steroid Biochem Mol Biol
, vol.87
, pp. 35-45
-
-
Haynes, B.P.1
Dowsett, M.2
Miller, W.R.3
Dixon, J.M.4
Bhatnagar, A.S.5
-
37
-
-
77950348421
-
Aromatase and in situ estrogen production in DCIS (ductal carcinoma in situ) of human breast
-
doi:10.1016/j.jsbmb.2009.09.008
-
Sasano H, Miki Y, Shibuya R, Suzuki T. Aromatase and in situ estrogen production in DCIS (ductal carcinoma in situ) of human breast. J Steroid Biochem Mol Biol (2010) 118:242-5. doi:10.1016/j.jsbmb.2009.09.008
-
(2010)
J Steroid Biochem Mol Biol
, vol.118
, pp. 242-245
-
-
Sasano, H.1
Miki, Y.2
Shibuya, R.3
Suzuki, T.4
-
38
-
-
0642375461
-
Aromatase inhibitors in prevention-data from the ATAC (Arimidex, tamoxifen alone or in combination) trial and the design of IBIS-II (the second International Breast Cancer Intervention Study)
-
doi:10.1007/978-3-642-55647-0_9 discussion 264-106
-
Cuzick J. Aromatase inhibitors in prevention-data from the ATAC (Arimidex, tamoxifen alone or in combination) trial and the design of IBIS-II (the second International Breast Cancer Intervention Study). Recent Results Cancer Res (2003) 163:96-103. doi:10.1007/978-3-642-55647-0_9 discussion 264-106
-
(2003)
Recent Results Cancer Res
, vol.163
, pp. 96-103
-
-
Cuzick, J.1
-
39
-
-
68949172393
-
Clinical perspectives on the utility of aromatase inhibitors for the adjuvant treatment of breast cancer
-
doi:10.1016/S0960-9776(09)70002-5
-
Chlebowski R, Cuzick J, Amakye D, Bauerfeind I, Buzdar A, Chia S, et al. Clinical perspectives on the utility of aromatase inhibitors for the adjuvant treatment of breast cancer. Breast (2009) 18(Suppl 2):S1-11. doi:10.1016/S0960-9776(09)70002-5
-
(2009)
Breast
, vol.18
, Issue.SUPPL. 2
-
-
Chlebowski, R.1
Cuzick, J.2
Amakye, D.3
Bauerfeind, I.4
Buzdar, A.5
Chia, S.6
-
40
-
-
24744450378
-
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17
-
doi:10.1093/jnci/dji250
-
Goss PE, Ingle JN, Martino S, Robert NJ, Muss HB, Piccart MJ, et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. J Natl Cancer Inst (2005) 97:1262-71. doi:10.1093/jnci/dji250
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1262-1271
-
-
Goss, P.E.1
Ingle, J.N.2
Martino, S.3
Robert, N.J.4
Muss, H.B.5
Piccart, M.J.6
-
41
-
-
37449028688
-
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial
-
doi:10.1016/S1470-2045(07)70385-6
-
Forbes JF, Cuzick J, Buzdar A, Howell A, Tobias JS, Baum M. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet Oncol (2008) 9:45-53. doi:10.1016/S1470-2045(07)70385-6
-
(2008)
Lancet Oncol
, vol.9
, pp. 45-53
-
-
Forbes, J.F.1
Cuzick, J.2
Buzdar, A.3
Howell, A.4
Tobias, J.S.5
Baum, M.6
-
42
-
-
34547625250
-
The National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: an international breast cancer prevention trial
-
doi:10.3747/co.2007.117
-
Richardson H, Johnston D, Pater J, Goss P. The National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: an international breast cancer prevention trial. Curr Oncol (2007) 14:89-96. doi:10.3747/co.2007.117
-
(2007)
Curr Oncol
, vol.14
, pp. 89-96
-
-
Richardson, H.1
Johnston, D.2
Pater, J.3
Goss, P.4
-
43
-
-
22644440299
-
Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma
-
doi:10.1111/j.1075-122x.2005.21463.x
-
Ariga R, Zarif A, Korasick J, Reddy V, Siziopikou K, Gattuso P. Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma. Breast J (2005) 11:278-80. doi:10.1111/j.1075-122x.2005.21463.x
-
(2005)
Breast J
, vol.11
, pp. 278-280
-
-
Ariga, R.1
Zarif, A.2
Korasick, J.3
Reddy, V.4
Siziopikou, K.5
Gattuso, P.6
-
44
-
-
18344390418
-
ERBB receptors and cancer: the complexity of targeted inhibitors
-
doi:10.1038/nrc1667
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer (2005) 5:341-54. doi:10.1038/nrc1667
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
45
-
-
59049104410
-
Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice
-
doi:10.1093/jnci/djn436
-
Strecker TE, Shen Q, Zhang Y, Hill JL, Li Y, Wang C, et al. Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice. J Natl Cancer Inst (2009) 101:107-13. doi:10.1093/jnci/djn436
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 107-113
-
-
Strecker, T.E.1
Shen, Q.2
Zhang, Y.3
Hill, J.L.4
Li, Y.5
Wang, C.6
-
46
-
-
0348230978
-
Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors
-
doi:10.1093/jnci/djg117
-
Lu C, Speers C, Zhang Y, Xu X, Hill J, Steinbis E, et al. Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors. J Natl Cancer Inst (2003) 95:1825-33. doi:10.1093/jnci/djg117
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1825-1833
-
-
Lu, C.1
Speers, C.2
Zhang, Y.3
Xu, X.4
Hill, J.5
Steinbis, E.6
-
47
-
-
84866511734
-
Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera
-
doi:10.1158/1940-6207.CAPR-11-0558
-
Lu H, Ladd J, Feng Z, Wu M, Goodell V, Pitteri SJ, et al. Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera. Cancer Prev Res (Phila) (2012) 5:1036-43. doi:10.1158/1940-6207.CAPR-11-0558
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 1036-1043
-
-
Lu, H.1
Ladd, J.2
Feng, Z.3
Wu, M.4
Goodell, V.5
Pitteri, S.J.6
-
48
-
-
77953398645
-
HER-2/neu as a target for cancer vaccines
-
doi:10.2217/imt.09.89
-
Baxevanis CN, Voutsas IF, Gritzapis AD, Perez SA, Papamichail M. HER-2/neu as a target for cancer vaccines. Immunotherapy (2010) 2:213-26. doi:10.2217/imt.09.89
-
(2010)
Immunotherapy
, vol.2
, pp. 213-226
-
-
Baxevanis, C.N.1
Voutsas, I.F.2
Gritzapis, A.D.3
Perez, S.A.4
Papamichail, M.5
-
49
-
-
49149117772
-
Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide (AE37) vaccine
-
doi:10.1200/JCO.2007.15.7842
-
Holmes JP, Benavides LC, Gates JD, Carmichael MG, Hueman MT, Mittendorf EA, et al. Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide (AE37) vaccine. J Clin Oncol (2008) 26:3426-33. doi:10.1200/JCO.2007.15.7842
-
(2008)
J Clin Oncol
, vol.26
, pp. 3426-3433
-
-
Holmes, J.P.1
Benavides, L.C.2
Gates, J.D.3
Carmichael, M.G.4
Hueman, M.T.5
Mittendorf, E.A.6
-
50
-
-
75649136936
-
Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients: United States Military Cancer Institute Clinical Trials Group Study I-04
-
doi:10.1002/cncr.24756
-
Carmichael MG, Benavides LC, Holmes JP, Gates JD, Mittendorf EA, Ponniah S, et al. Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients: United States Military Cancer Institute Clinical Trials Group Study I-04. Cancer (2010) 116:292-301. doi:10.1002/cncr.24756
-
(2010)
Cancer
, vol.116
, pp. 292-301
-
-
Carmichael, M.G.1
Benavides, L.C.2
Holmes, J.P.3
Gates, J.D.4
Mittendorf, E.A.5
Ponniah, S.6
-
51
-
-
84860700518
-
Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
doi:10.1002/cncr.26574
-
Mittendorf EA, Clifton GT, Holmes JP, Clive KS, Patil R, Benavides LC, et al. Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer (2012) 118:2594-602. doi:10.1002/cncr.26574
-
(2012)
Cancer
, vol.118
, pp. 2594-2602
-
-
Mittendorf, E.A.1
Clifton, G.T.2
Holmes, J.P.3
Clive, K.S.4
Patil, R.5
Benavides, L.C.6
-
52
-
-
70350235064
-
Identification of novel kinase targets for the treatment of estrogen receptor-negative breast cancer
-
doi:10.1158/1078-0432.CCR-09-1107
-
Speers C, Tsimelzon A, Sexton K, Herrick AM, Gutierrez C, Culhane A, et al. Identification of novel kinase targets for the treatment of estrogen receptor-negative breast cancer. Clin Cancer Res (2009) 15:6327-40. doi:10.1158/1078-0432.CCR-09-1107
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6327-6340
-
-
Speers, C.1
Tsimelzon, A.2
Sexton, K.3
Herrick, A.M.4
Gutierrez, C.5
Culhane, A.6
-
53
-
-
12844252576
-
Retinoid X receptors: X-ploring their (patho)physiological functions
-
doi:10.1038/sj.cdd.4401533
-
Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L. Retinoid X receptors: X-ploring their (patho)physiological functions. Cell Death Differ (2004) 11(Suppl 2):S126-43. doi:10.1038/sj.cdd.4401533
-
(2004)
Cell Death Differ
, vol.11
, Issue.SUPPL. 2
-
-
Szanto, A.1
Narkar, V.2
Shen, Q.3
Uray, I.P.4
Davies, P.J.5
Nagy, L.6
-
54
-
-
0033813160
-
9-Cis-retinoic acid suppresses mammary tumorigenesis in C3(1)-simian virus 40 T antigen-transgenic mice
-
Wu K, Kim HT, Rodriquez JL, Munoz-Medellin D, Mohsin SK, Hilsenbeck SG, et al. 9-Cis-retinoic acid suppresses mammary tumorigenesis in C3(1)-simian virus 40 T antigen-transgenic mice. Clin Cancer Res (2000) 6:3696-704.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3696-3704
-
-
Wu, K.1
Kim, H.T.2
Rodriquez, J.L.3
Munoz-Medellin, D.4
Mohsin, S.K.5
Hilsenbeck, S.G.6
-
55
-
-
0036094845
-
Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid
-
Wu K, Kim HT, Rodriquez JL, Hilsenbeck SG, Mohsin SK, Xu XC, et al. Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid. Cancer Epidemiol Biomarkers Prev (2002) 11:467-74.
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 467-474
-
-
Wu, K.1
Kim, H.T.2
Rodriquez, J.L.3
Hilsenbeck, S.G.4
Mohsin, S.K.5
Xu, X.C.6
-
56
-
-
0037112520
-
The retinoid X receptor-selective retinoid, LGD1069, prevents the development of estrogen receptor-negative mammary tumors in transgenic mice
-
Wu K, Zhang Y, Xu XC, Hill J, Celestino J, Kim HT, et al. The retinoid X receptor-selective retinoid, LGD1069, prevents the development of estrogen receptor-negative mammary tumors in transgenic mice. Cancer Res (2002) 62:6376-80.
-
(2002)
Cancer Res
, vol.62
, pp. 6376-6380
-
-
Wu, K.1
Zhang, Y.2
Xu, X.C.3
Hill, J.4
Celestino, J.5
Kim, H.T.6
-
57
-
-
35949000084
-
The rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice
-
doi:10.1158/1078-0432.CCR-06-2681
-
Li Y, Zhang Y, Hill J, Shen Q, Kim HT, Xu X, et al. The rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice. Clin Cancer Res (2007) 13:6224-31. doi:10.1158/1078-0432.CCR-06-2681
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6224-6231
-
-
Li, Y.1
Zhang, Y.2
Hill, J.3
Shen, Q.4
Kim, H.T.5
Xu, X.6
-
58
-
-
42149183454
-
The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice
-
doi:10.1038/sj.bjc.6604320
-
Li Y, Zhang Y, Hill J, Kim HT, Shen Q, Bissonnette RP, et al. The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice. Br J Cancer (2008) 98:1380-8. doi:10.1038/sj.bjc.6604320
-
(2008)
Br J Cancer
, vol.98
, pp. 1380-1388
-
-
Li, Y.1
Zhang, Y.2
Hill, J.3
Kim, H.T.4
Shen, Q.5
Bissonnette, R.P.6
-
59
-
-
84989611379
-
Tissue changes following deprivation of fat-soluble a vitamin
-
doi:10.1084/jem.42.6.753
-
Wolbach SB, Howe PR. Tissue changes following deprivation of fat-soluble a vitamin. J Exp Med (1925) 42:753-77. doi:10.1084/jem.42.6.753
-
(1925)
J Exp Med
, vol.42
, pp. 753-777
-
-
Wolbach, S.B.1
Howe, P.R.2
-
60
-
-
0018778594
-
N-(4-hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat
-
Moon RC, Thompson HJ, Becci PJ, Grubbs CJ, Gander RJ, Newton DL, et al. N-(4-hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat. Cancer Res (1979) 39:1339-46.
-
(1979)
Cancer Res
, vol.39
, pp. 1339-1346
-
-
Moon, R.C.1
Thompson, H.J.2
Becci, P.J.3
Grubbs, C.J.4
Gander, R.J.5
Newton, D.L.6
-
61
-
-
0025091456
-
Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck
-
doi:10.1056/NEJM199009203231205
-
Hong WK, Lippman SM, Itri LM, Karp DD, Lee JS, Byers RM, et al. Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Engl J Med (1990) 323:795-801. doi:10.1056/NEJM199009203231205
-
(1990)
N Engl J Med
, vol.323
, pp. 795-801
-
-
Hong, W.K.1
Lippman, S.M.2
Itri, L.M.3
Karp, D.D.4
Lee, J.S.5
Byers, R.M.6
-
62
-
-
19244371699
-
Phase I clinical trial of alitretinoin and tamoxifen in breast cancer patients: toxicity, pharmacokinetic, and biomarker evaluations
-
Lawrence JA, Adamson PC, Caruso R, Chow C, Kleiner D, Murphy RF, et al. Phase I clinical trial of alitretinoin and tamoxifen in breast cancer patients: toxicity, pharmacokinetic, and biomarker evaluations. J Clin Oncol (2001) 19:2754-63.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2754-2763
-
-
Lawrence, J.A.1
Adamson, P.C.2
Caruso, R.3
Chow, C.4
Kleiner, D.5
Murphy, R.F.6
-
63
-
-
12244302882
-
The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: results of a randomized double-blind clinical trial
-
Alvarez RD, Conner MG, Weiss H, Klug PM, Niwas S, Manne U, et al. The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: results of a randomized double-blind clinical trial. Cancer Epidemiol Biomarkers Prev (2003) 12:114-9.
-
(2003)
Cancer Epidemiol Biomarkers Prev
, vol.12
, pp. 114-119
-
-
Alvarez, R.D.1
Conner, M.G.2
Weiss, H.3
Klug, P.M.4
Niwas, S.5
Manne, U.6
-
64
-
-
0033520713
-
Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer
-
doi:10.1093/jnci/91.21.1847
-
Veronesi U, De Palo G, Marubini E, Costa A, Formelli F, Mariani L, et al. Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer. J Natl Cancer Inst (1999) 91:1847-56. doi:10.1093/jnci/91.21.1847
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1847-1856
-
-
Veronesi, U.1
De Palo, G.2
Marubini, E.3
Costa, A.4
Formelli, F.5
Mariani, L.6
-
65
-
-
33745613818
-
Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancer
-
doi:10.1093/annonc/mdl047
-
Veronesi U, Mariani L, Decensi A, Formelli F, Camerini T, Miceli R, et al. Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancer. Ann Oncol (2006) 17:1065-71. doi:10.1093/annonc/mdl047
-
(2006)
Ann Oncol
, vol.17
, pp. 1065-1071
-
-
Veronesi, U.1
Mariani, L.2
Decensi, A.3
Formelli, F.4
Camerini, T.5
Miceli, R.6
-
66
-
-
0036311173
-
Effect of fenretinide on ovarian carcinoma occurrence
-
doi:10.1006/gyno.2002.6663
-
De Palo G, Mariani L, Camerini T, Marubini E, Formelli F, Pasini B, et al. Effect of fenretinide on ovarian carcinoma occurrence. Gynecol Oncol (2002) 86:24-7. doi:10.1006/gyno.2002.6663
-
(2002)
Gynecol Oncol
, vol.86
, pp. 24-27
-
-
De Palo, G.1
Mariani, L.2
Camerini, T.3
Marubini, E.4
Formelli, F.5
Pasini, B.6
-
67
-
-
33746038942
-
The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells
-
doi:10.1158/1535-7163.MCT-06-0136
-
Ji Y, Lee HJ, Goodman C, Uskokovic M, Liby K, Sporn M, et al. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells. Mol Cancer Ther (2006) 5:1452-8. doi:10.1158/1535-7163.MCT-06-0136
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1452-1458
-
-
Ji, Y.1
Lee, H.J.2
Goodman, C.3
Uskokovic, M.4
Liby, K.5
Sporn, M.6
-
68
-
-
84867373769
-
The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice
-
doi:10.1158/1940-6207.CAPR-11-0524
-
Mazumdar A, Medina D, Kittrell FS, Zhang Y, Hill JL, Edwards DE, et al. The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice. Cancer Prev Res (Phila) (2012) 5:1195-202. doi:10.1158/1940-6207.CAPR-11-0524
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 1195-1202
-
-
Mazumdar, A.1
Medina, D.2
Kittrell, F.S.3
Zhang, Y.4
Hill, J.L.5
Edwards, D.E.6
-
69
-
-
0036143027
-
Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast
-
Chan KC, Knox WF, Gee JM, Morris J, Nicholson RI, Potten CS, et al. Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast. Cancer Res (2002) 62:122-8.
-
(2002)
Cancer Res
, vol.62
, pp. 122-128
-
-
Chan, K.C.1
Knox, W.F.2
Gee, J.M.3
Morris, J.4
Nicholson, R.I.5
Potten, C.S.6
-
70
-
-
40349096373
-
Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu
-
doi:10.1002/ijc.23231
-
Piechocki MP, Dibbley SK, Lonardo F, Yoo GH. Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu. Int J Cancer (2008) 122:1722-9. doi:10.1002/ijc.23231
-
(2008)
Int J Cancer
, vol.122
, pp. 1722-1729
-
-
Piechocki, M.P.1
Dibbley, S.K.2
Lonardo, F.3
Yoo, G.H.4
-
71
-
-
75849118878
-
Targeting the PI3K signaling pathway in cancer
-
doi:10.1016/j.gde.2009.11.002
-
Wong KK, Engelman JA, Cantley LC. Targeting the PI3K signaling pathway in cancer. Curr Opin Genet Dev (2010) 20:87-90. doi:10.1016/j.gde.2009.11.002
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 87-90
-
-
Wong, K.K.1
Engelman, J.A.2
Cantley, L.C.3
-
72
-
-
74549131244
-
Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
-
doi:10.4161/cc.9.1.10407
-
Anisimov VN, Egormin PA, Piskunova TS, Popovich IG, Tyndyk ML, Yurova MN, et al. Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle (2010) 9:188-97. doi:10.4161/cc.9.1.10407
-
(2010)
Cell Cycle
, vol.9
, pp. 188-197
-
-
Anisimov, V.N.1
Egormin, P.A.2
Piskunova, T.S.3
Popovich, I.G.4
Tyndyk, M.L.5
Yurova, M.N.6
-
73
-
-
33845745288
-
Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland
-
doi:10.1158/0008-5472.CAN-06-2316
-
Torres-Arzayus MI, Yuan J, Dellagatta JL, Lane H, Kung AL, Brown M. Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland. Cancer Res (2006) 66:11381-8. doi:10.1158/0008-5472.CAN-06-2316
-
(2006)
Cancer Res
, vol.66
, pp. 11381-11388
-
-
Torres-Arzayus, M.I.1
Yuan, J.2
Dellagatta, J.L.3
Lane, H.4
Kung, A.L.5
Brown, M.6
-
74
-
-
64949114063
-
Rapamycin effects on mTOR signaling in benign, premalignant and malignant human breast epithelial cells
-
Kim SH, Zukowski K, Novak RF. Rapamycin effects on mTOR signaling in benign, premalignant and malignant human breast epithelial cells. Anticancer Res (2009) 29:1143-50.
-
(2009)
Anticancer Res
, vol.29
, pp. 1143-1150
-
-
Kim, S.H.1
Zukowski, K.2
Novak, R.F.3
-
75
-
-
84862646284
-
Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug
-
doi:10.1016/j.ajpath.2012.03.017
-
Mercier I, Camacho J, Titchen K, Gonzales DM, Quann K, Bryant KG, et al. Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug. Am J Pathol (2012) 181:278-93. doi:10.1016/j.ajpath.2012.03.017
-
(2012)
Am J Pathol
, vol.181
, pp. 278-293
-
-
Mercier, I.1
Camacho, J.2
Titchen, K.3
Gonzales, D.M.4
Quann, K.5
Bryant, K.G.6
-
76
-
-
58849129168
-
BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells
-
doi:10.1158/1078-0432.CCR-08-0801
-
Litzenburger BC, Kim HJ, Kuiatse I, Carboni JM, Attar RM, Gottardis MM, et al. BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells. Clin Cancer Res (2009) 15:226-37. doi:10.1158/1078-0432.CCR-08-0801
-
(2009)
Clin Cancer Res
, vol.15
, pp. 226-237
-
-
Litzenburger, B.C.1
Kim, H.J.2
Kuiatse, I.3
Carboni, J.M.4
Attar, R.M.5
Gottardis, M.M.6
-
77
-
-
0036177671
-
Cyclooxygenase-2: a therapeutic target
-
doi:10.1146/annurev.med.53.082901.103952
-
Turini ME, DuBois RN. Cyclooxygenase-2: a therapeutic target. Annu Rev Med (2002) 53:35-57. doi:10.1146/annurev.med.53.082901.103952
-
(2002)
Annu Rev Med
, vol.53
, pp. 35-57
-
-
Turini, M.E.1
DuBois, R.N.2
-
78
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
doi:10.1056/NEJM200006293422603
-
Steinbach G, Lynch PM, Phillips RK, Wallace MH, Hawk E, Gordon GB, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med (2000) 342:1946-52. doi:10.1056/NEJM200006293422603
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
Wallace, M.H.4
Hawk, E.5
Gordon, G.B.6
-
79
-
-
33845288081
-
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas
-
doi:10.1053/j.gastro.2006.08.079
-
Baron JA, Sandler RS, Bresalier RS, Quan H, Riddell R, Lanas A, et al. A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology (2006) 131:1674-82. doi:10.1053/j.gastro.2006.08.079
-
(2006)
Gastroenterology
, vol.131
, pp. 1674-1682
-
-
Baron, J.A.1
Sandler, R.S.2
Bresalier, R.S.3
Quan, H.4
Riddell, R.5
Lanas, A.6
-
80
-
-
33748180713
-
Celecoxib for the prevention of colorectal adenomatous polyps
-
doi:10.1056/NEJMoa061652
-
Arber N, Eagle CJ, Spicak J, Racz I, Dite P, Hajer J, et al. Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med (2006) 355:885-95. doi:10.1056/NEJMoa061652
-
(2006)
N Engl J Med
, vol.355
, pp. 885-895
-
-
Arber, N.1
Eagle, C.J.2
Spicak, J.3
Racz, I.4
Dite, P.5
Hajer, J.6
-
81
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
doi:10.1056/NEJMoa050405
-
Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R, Finn P, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med (2005) 352:1071-80. doi:10.1056/NEJMoa050405
-
(2005)
N Engl J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
-
82
-
-
0036792206
-
Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer
-
Howe LR, Subbaramaiah K, Patel J, Masferrer JL, Deora A, Hudis C, et al. Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer. Cancer Res (2002) 62:5405-7.
-
(2002)
Cancer Res
, vol.62
, pp. 5405-5407
-
-
Howe, L.R.1
Subbaramaiah, K.2
Patel, J.3
Masferrer, J.L.4
Deora, A.5
Hudis, C.6
-
83
-
-
0035805054
-
Breast cancer and NSAID use: a meta-analysis
-
doi:10.1054/bjoc.2000.1709
-
Khuder SA, Mutgi AB. Breast cancer and NSAID use: a meta-analysis. Br J Cancer (2001) 84:1188-92. doi:10.1054/bjoc.2000.1709
-
(2001)
Br J Cancer
, vol.84
, pp. 1188-1192
-
-
Khuder, S.A.1
Mutgi, A.B.2
-
84
-
-
54049109591
-
Breast cancer and use of nonsteroidal anti-inflammatory drugs: a meta-analysis
-
doi:10.1093/jnci/djn324
-
Takkouche B, Regueira-Mendez C, Etminan M. Breast cancer and use of nonsteroidal anti-inflammatory drugs: a meta-analysis. J Natl Cancer Inst (2008) 100:1439-47. doi:10.1093/jnci/djn324
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1439-1447
-
-
Takkouche, B.1
Regueira-Mendez, C.2
Etminan, M.3
-
85
-
-
34547127614
-
Diabetes mellitus and risk of breast cancer: a meta-analysis
-
doi:10.1002/ijc.22717
-
Larsson SC, Mantzoros CS, Wolk A. Diabetes mellitus and risk of breast cancer: a meta-analysis. Int J Cancer (2007) 121:856-62. doi:10.1002/ijc.22717
-
(2007)
Int J Cancer
, vol.121
, pp. 856-862
-
-
Larsson, S.C.1
Mantzoros, C.S.2
Wolk, A.3
-
86
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
doi:10.1126/science.1120781
-
Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science (2005) 310:1642-6. doi:10.1126/science.1120781
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.H.4
Bardeesy, N.5
Depinho, R.A.6
-
87
-
-
33751284806
-
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
-
doi:10.1158/0008-5472.CAN-06-1500
-
Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M. Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res (2006) 66:10269-73. doi:10.1158/0008-5472.CAN-06-1500
-
(2006)
Cancer Res
, vol.66
, pp. 10269-10273
-
-
Zakikhani, M.1
Dowling, R.2
Fantus, I.G.3
Sonenberg, N.4
Pollak, M.5
-
88
-
-
60749108023
-
The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells
-
doi:10.4161/cc.8.1.7499
-
Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA. The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells. Cell Cycle (2009) 8:88-96. doi:10.4161/cc.8.1.7499
-
(2009)
Cell Cycle
, vol.8
, pp. 88-96
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Menendez, J.A.3
-
89
-
-
25444462729
-
Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice
-
doi:10.1007/s10517-005-0389-9
-
Anisimov VN, Egormin PA, Bershtein LM, Zabezhinskii MA, Piskunova TS, Popovich IG, et al. Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice. Bull Exp Biol Med (2005) 139:721-3. doi:10.1007/s10517-005-0389-9
-
(2005)
Bull Exp Biol Med
, vol.139
, pp. 721-723
-
-
Anisimov, V.N.1
Egormin, P.A.2
Bershtein, L.M.3
Zabezhinskii, M.A.4
Piskunova, T.S.5
Popovich, I.G.6
-
90
-
-
79151478459
-
Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents
-
doi:10.1007/s10549-010-1224-1
-
Goodwin PJ, Stambolic V, Lemieux J, Chen BE, Parulekar WR, Gelmon KA, et al. Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents. Breast Cancer Res Treat (2011) 126:215-20. doi:10.1007/s10549-010-1224-1
-
(2011)
Breast Cancer Res Treat
, vol.126
, pp. 215-220
-
-
Goodwin, P.J.1
Stambolic, V.2
Lemieux, J.3
Chen, B.E.4
Parulekar, W.R.5
Gelmon, K.A.6
-
91
-
-
79960845901
-
Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial
-
doi:10.1007/s10549-011-1612-1
-
Hadad S, Iwamoto T, Jordan L, Purdie C, Bray S, Baker L, et al. Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial. Breast Cancer Res Treat (2011) 128:783-94. doi:10.1007/s10549-011-1612-1
-
(2011)
Breast Cancer Res Treat
, vol.128
, pp. 783-794
-
-
Hadad, S.1
Iwamoto, T.2
Jordan, L.3
Purdie, C.4
Bray, S.5
Baker, L.6
-
92
-
-
84864075329
-
Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial
-
doi:10.1200/JCO.2011.39.3769
-
Bonanni B, Puntoni M, Cazzaniga M, Pruneri G, Serrano D, Guerrieri-Gonzaga A, et al. Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial. J Clin Oncol (2012) 30:2593-600. doi:10.1200/JCO.2011.39.3769
-
(2012)
J Clin Oncol
, vol.30
, pp. 2593-2600
-
-
Bonanni, B.1
Puntoni, M.2
Cazzaniga, M.3
Pruneri, G.4
Serrano, D.5
Guerrieri-Gonzaga, A.6
-
93
-
-
84866538325
-
Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study
-
doi:10.1007/s10549-012-2223-1
-
Niraula S, Dowling RJ, Ennis M, Chang MC, Done SJ, Hood N, et al. Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study. Breast Cancer Res Treat (2012) 135:821-30. doi:10.1007/s10549-012-2223-1
-
(2012)
Breast Cancer Res Treat
, vol.135
, pp. 821-830
-
-
Niraula, S.1
Dowling, R.J.2
Ennis, M.3
Chang, M.C.4
Done, S.J.5
Hood, N.6
-
94
-
-
0037489726
-
Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells
-
doi:10.1097/01.GME.0000055485.06076.00
-
Mueck AO, Seeger H, Wallwiener D. Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells. Menopause (2003) 10:332-6. doi:10.1097/01.GME.0000055485.06076.00
-
(2003)
Menopause
, vol.10
, pp. 332-336
-
-
Mueck, A.O.1
Seeger, H.2
Wallwiener, D.3
-
95
-
-
33749040295
-
Breast cancer growth prevention by statins
-
doi:10.1158/0008-5472.CAN-05-4061
-
Campbell MJ, Esserman LJ, Zhou Y, Shoemaker M, Lobo M, Borman E, et al. Breast cancer growth prevention by statins. Cancer Res (2006) 66:8707-14. doi:10.1158/0008-5472.CAN-05-4061
-
(2006)
Cancer Res
, vol.66
, pp. 8707-8714
-
-
Campbell, M.J.1
Esserman, L.J.2
Zhou, Y.3
Shoemaker, M.4
Lobo, M.5
Borman, E.6
-
96
-
-
0036227123
-
Statin use and the risk of breast and prostate cancer
-
doi:10.1097/00001648-200205000-00005
-
Coogan PF, Rosenberg L, Palmer JR, Strom BL, Zauber AG, Shapiro S. Statin use and the risk of breast and prostate cancer. Epidemiology (2002) 13:262-7. doi:10.1097/00001648-200205000-00005
-
(2002)
Epidemiology
, vol.13
, pp. 262-267
-
-
Coogan, P.F.1
Rosenberg, L.2
Palmer, J.R.3
Strom, B.L.4
Zauber, A.G.5
Shapiro, S.6
-
97
-
-
84865144986
-
Statin use and risk of breast cancer: a meta-analysis of observational studies
-
doi:10.1007/s10549-012-2154-x
-
Undela K, Srikanth V, Bansal D. Statin use and risk of breast cancer: a meta-analysis of observational studies. Breast Cancer Res Treat (2012) 135:261-9. doi:10.1007/s10549-012-2154-x
-
(2012)
Breast Cancer Res Treat
, vol.135
, pp. 261-269
-
-
Undela, K.1
Srikanth, V.2
Bansal, D.3
-
98
-
-
33646450789
-
A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes
-
doi:10.1200/JCO.2005.04.9882 author reply 2127-2128
-
Kumar AS, Campbell M, Benz CC, Esserman LJ. A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes. J Clin Oncol (2006) 24:2127. doi:10.1200/JCO.2005.04.9882 author reply 2127-2128
-
(2006)
J Clin Oncol
, vol.24
, pp. 2127
-
-
Kumar, A.S.1
Campbell, M.2
Benz, C.C.3
Esserman, L.J.4
-
99
-
-
33644846806
-
Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies
-
doi:10.1200/JCO.2005.02.7045
-
Bonovas S, Filioussi K, Tsavaris N, Sitaras NM. Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies. J Clin Oncol (2005) 23:8606-12. doi:10.1200/JCO.2005.02.7045
-
(2005)
J Clin Oncol
, vol.23
, pp. 8606-8612
-
-
Bonovas, S.1
Filioussi, K.2
Tsavaris, N.3
Sitaras, N.M.4
-
100
-
-
72449163475
-
Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer
-
doi:10.1007/s10549-009-0507-x
-
Garwood ER, Kumar AS, Baehner FL, Moore DH, Au A, Hylton N, et al. Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer. Breast Cancer Res Treat (2010) 119:137-44. doi:10.1007/s10549-009-0507-x
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 137-144
-
-
Garwood, E.R.1
Kumar, A.S.2
Baehner, F.L.3
Moore, D.H.4
Au, A.5
Hylton, N.6
-
101
-
-
84856235374
-
A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer
-
doi:10.1007/s10549-011-1858-7
-
Higgins MJ, Prowell TM, Blackford AL, Byrne C, Khouri NF, Slater SA, et al. A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer. Breast Cancer Res Treat (2012) 131:915-24. doi:10.1007/s10549-011-1858-7
-
(2012)
Breast Cancer Res Treat
, vol.131
, pp. 915-924
-
-
Higgins, M.J.1
Prowell, T.M.2
Blackford, A.L.3
Byrne, C.4
Khouri, N.F.5
Slater, S.A.6
-
102
-
-
79551513949
-
Chemoprevention of hormone receptor-negative breast cancer: new approaches needed
-
doi:10.1007/978-3-642-10858-7_13
-
Uray IP, Brown PH. Chemoprevention of hormone receptor-negative breast cancer: new approaches needed. Recent Results Cancer Res (2011) 188:147-62. doi:10.1007/978-3-642-10858-7_13
-
(2011)
Recent Results Cancer Res
, vol.188
, pp. 147-162
-
-
Uray, I.P.1
Brown, P.H.2
-
103
-
-
33745225169
-
Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair
-
doi:10.1016/S0076-6879(05)09029-4
-
Dantzer F, Ame JC, Schreiber V, Nakamura J, Menissier-de Murcia J, de Murcia G. Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair. Methods Enzymol (2006) 409:493-510. doi:10.1016/S0076-6879(05)09029-4
-
(2006)
Methods Enzymol
, vol.409
, pp. 493-510
-
-
Dantzer, F.1
Ame, J.C.2
Schreiber, V.3
Nakamura, J.4
Menissier-de Murcia, J.5
de Murcia, G.6
-
104
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
doi:10.1038/nature03443
-
Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature (2005) 434:913-7. doi:10.1038/nature03443
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
-
105
-
-
84878594500
-
Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers
-
doi:10.1038/bjc.2013.144
-
Lips EH, Mulder L, Oonk A, van der Kolk LE, Hogervorst FB, Imholz AL, et al. Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers. Br J Cancer (2013) 108:2172-7. doi:10.1038/bjc.2013.144
-
(2013)
Br J Cancer
, vol.108
, pp. 2172-2177
-
-
Lips, E.H.1
Mulder, L.2
Oonk, A.3
van der Kolk, L.E.4
Hogervorst, F.B.5
Imholz, A.L.6
-
106
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
doi:10.1056/NEJMoa0900212
-
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med (2009) 361:123-34. doi:10.1056/NEJMoa0900212
-
(2009)
N Engl J Med
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
Mergui-Roelvink, M.6
-
107
-
-
77956224281
-
Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer
-
Liang H, Tan AR. Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer. IDrugs (2010) 13:646-56.
-
(2010)
IDrugs
, vol.13
, pp. 646-656
-
-
Liang, H.1
Tan, A.R.2
-
108
-
-
31544464616
-
In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417
-
doi:10.1158/0008-5472.CAN-05-1107
-
Haluska P, Carboni JM, Loegering DA, Lee FY, Wittman M, Saulnier MG, et al. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417. Cancer Res (2006) 66:362-71. doi:10.1158/0008-5472.CAN-05-1107
-
(2006)
Cancer Res
, vol.66
, pp. 362-371
-
-
Haluska, P.1
Carboni, J.M.2
Loegering, D.A.3
Lee, F.Y.4
Wittman, M.5
Saulnier, M.G.6
-
109
-
-
79954575067
-
High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy
-
doi:10.1158/1078-0432.CCR-10-1903
-
Litzenburger BC, Creighton CJ, Tsimelzon A, Chan BT, Hilsenbeck SG, Wang T, et al. High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res (2011) 17:2314-27. doi:10.1158/1078-0432.CCR-10-1903
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2314-2327
-
-
Litzenburger, B.C.1
Creighton, C.J.2
Tsimelzon, A.3
Chan, B.T.4
Hilsenbeck, S.G.5
Wang, T.6
-
110
-
-
33746637660
-
Current development of mTOR inhibitors as anticancer agents
-
doi:10.1038/nrd2062
-
Faivre S, Kroemer G, Raymond E. Current development of mTOR inhibitors as anticancer agents. Nat Rev Drug Discov (2006) 5:671-88. doi:10.1038/nrd2062
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 671-688
-
-
Faivre, S.1
Kroemer, G.2
Raymond, E.3
-
112
-
-
18244391514
-
Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
-
doi:10.1038/sj.bjc.6600126
-
Perez-Tenorio G, Stal O. Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br J Cancer (2002) 86:540-5. doi:10.1038/sj.bjc.6600126
-
(2002)
Br J Cancer
, vol.86
, pp. 540-545
-
-
Perez-Tenorio, G.1
Stal, O.2
-
113
-
-
16644393213
-
The PIK3CA gene is mutated with high frequency in human breast cancers
-
doi:10.4161/cbt.3.8.994
-
Bachman KE, Argani P, Samuels Y, Silliman N, Ptak J, Szabo S, et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther (2004) 3:772-5. doi:10.4161/cbt.3.8.994
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 772-775
-
-
Bachman, K.E.1
Argani, P.2
Samuels, Y.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
-
114
-
-
2342559981
-
The TOR pathway: a target for cancer therapy
-
doi:10.1038/nrc1362
-
Bjornsti MA, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev Cancer (2004) 4:335-48. doi:10.1038/nrc1362
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
115
-
-
4043171462
-
Upstream and downstream of mTOR
-
doi:10.1101/gad.1212704
-
Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev (2004) 18:1926-45. doi:10.1101/gad.1212704
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
116
-
-
84874217042
-
Combining mTOR inhibitors with chemotherapy and other targeted therapies in advanced breast cancer: rationale, clinical experience, and future directions
-
doi:10.4137/BCBCR.S10071
-
Yardley DA. Combining mTOR inhibitors with chemotherapy and other targeted therapies in advanced breast cancer: rationale, clinical experience, and future directions. Breast Cancer (Auckl) (2013) 7:7-22. doi:10.4137/BCBCR.S10071
-
(2013)
Breast Cancer (Auckl)
, vol.7
, pp. 7-22
-
-
Yardley, D.A.1
-
117
-
-
84856444501
-
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial
-
doi:10.1016/S1470-2045(11)70397-7
-
Untch M, Loibl S, Bischoff J, Eidtmann H, Kaufmann M, Blohmer JU, et al. Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial. Lancet Oncol (2012) 13:135-44. doi:10.1016/S1470-2045(11)70397-7
-
(2012)
Lancet Oncol
, vol.13
, pp. 135-144
-
-
Untch, M.1
Loibl, S.2
Bischoff, J.3
Eidtmann, H.4
Kaufmann, M.5
Blohmer, J.U.6
-
118
-
-
84878396894
-
Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab-results of the randomised GeparQuinto study (GBG 44)
-
doi:10.1016/j.ejca.2013.02.027
-
Huober J, Fasching PA, Hanusch C, Rezai M, Eidtmann H, Kittel K, et al. Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab-results of the randomised GeparQuinto study (GBG 44). Eur J Cancer (2013) 49(10):2284-93. doi:10.1016/j.ejca.2013.02.027
-
(2013)
Eur J Cancer
, vol.49
, Issue.10
, pp. 2284-2293
-
-
Huober, J.1
Fasching, P.A.2
Hanusch, C.3
Rezai, M.4
Eidtmann, H.5
Kittel, K.6
-
119
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
-
doi:10.1056/NEJMoa1109653
-
Baselga J, Campone M, Piccart M, Burris HA III, Rugo HS, Sahmoud T, et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Engl J Med (2012) 366:520-9. doi:10.1056/NEJMoa1109653
-
(2012)
N Engl J Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
Campone, M.2
Piccart, M.3
Burris I.I.I, H.A.4
Rugo, H.S.5
Sahmoud, T.6
-
120
-
-
6944235337
-
Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt activity
-
doi:10.1158/1078-0432.CCR-04-0035
-
deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, et al. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt activity. Clin Cancer Res (2004) 10:8059-67. doi:10.1158/1078-0432.CCR-04-0035
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8059-8067
-
-
deGraffenried, L.A.1
Friedrichs, W.E.2
Russell, D.H.3
Donzis, E.J.4
Middleton, A.K.5
Silva, J.M.6
-
121
-
-
84876438500
-
The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001
-
doi:10.1002/mc.21878
-
De Angel RE, Conti CJ, Wheatley KE, Brenner AJ, Otto G, deGraffenried LA, et al. The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001. Mol Carcinog (2013) 52:446-58. doi:10.1002/mc.21878
-
(2013)
Mol Carcinog
, vol.52
, pp. 446-458
-
-
De Angel, R.E.1
Conti, C.J.2
Wheatley, K.E.3
Brenner, A.J.4
Otto, G.5
deGraffenried, L.A.6
-
122
-
-
84874333622
-
Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways
-
doi:10.1371/journal.pone.0056567
-
Andrade-Vieira R, Xu Z, Colp P, Marignani PA. Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways. PLoS One (2013) 8:e56567. doi:10.1371/journal.pone.0056567
-
(2013)
PLoS One
, vol.8
-
-
Andrade-Vieira, R.1
Xu, Z.2
Colp, P.3
Marignani, P.A.4
-
123
-
-
84875366769
-
Inhibition of S6K1 enhances glucose deprivation-induced cell death via downregulation of anti-apoptotic proteins in MCF-7 breast cancer cells
-
doi:10.1016/j.bbrc.2013.01.074
-
Choi HN, Jin HO, Kim JH, Hong SE, Kim HA, Kim EK, et al. Inhibition of S6K1 enhances glucose deprivation-induced cell death via downregulation of anti-apoptotic proteins in MCF-7 breast cancer cells. Biochem Biophys Res Commun (2013) 432:123-8. doi:10.1016/j.bbrc.2013.01.074
-
(2013)
Biochem Biophys Res Commun
, vol.432
, pp. 123-128
-
-
Choi, H.N.1
Jin, H.O.2
Kim, J.H.3
Hong, S.E.4
Kim, H.A.5
Kim, E.K.6
-
124
-
-
79952135852
-
The IGF pathway regulates ERalpha through a S6K1-dependent mechanism in breast cancer cells
-
doi:10.1210/me.2010-0373
-
Becker MA, Ibrahim YH, Cui X, Lee AV, Yee D. The IGF pathway regulates ERalpha through a S6K1-dependent mechanism in breast cancer cells. Mol Endocrinol (2011) 25:516-28. doi:10.1210/me.2010-0373
-
(2011)
Mol Endocrinol
, vol.25
, pp. 516-528
-
-
Becker, M.A.1
Ibrahim, Y.H.2
Cui, X.3
Lee, A.V.4
Yee, D.5
-
125
-
-
62649113168
-
Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells
-
doi:10.1186/bcr2202
-
Stratford AL, Fry CJ, Desilets C, Davies AH, Cho YY, Li Y, et al. Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells. Breast Cancer Res (2008) 10:R99. doi:10.1186/bcr2202
-
(2008)
Breast Cancer Res
, vol.10
-
-
Stratford, A.L.1
Fry, C.J.2
Desilets, C.3
Davies, A.H.4
Cho, Y.Y.5
Li, Y.6
-
126
-
-
77958556510
-
Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability
-
doi:10.1371/journal.pone.0012661
-
Law JH, Li Y, To K, Wang M, Astanehe A, Lambie K, et al. Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability. PLoS One (2010) 5(9):e12661. doi:10.1371/journal.pone.0012661
-
(2010)
PLoS One
, vol.5
, Issue.9
-
-
Law, J.H.1
Li, Y.2
To, K.3
Wang, M.4
Astanehe, A.5
Lambie, K.6
-
127
-
-
84874886131
-
Why US adults use dietary supplements
-
doi:10.1001/jamainternmed.2013.2299
-
Bailey RL, Gahche JJ, Miller PE, Thomas PR, Dwyer JT. Why US adults use dietary supplements. JAMA Intern Med (2013) 173:355-61. doi:10.1001/jamainternmed.2013.2299
-
(2013)
JAMA Intern Med
, vol.173
, pp. 355-361
-
-
Bailey, R.L.1
Gahche, J.J.2
Miller, P.E.3
Thomas, P.R.4
Dwyer, J.T.5
-
128
-
-
74849114005
-
Green tea consumption and breast cancer risk or recurrence: a meta-analysis
-
doi:10.1007/s10549-009-0415-0
-
Ogunleye AA, Xue F, Michels KB. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat (2010) 119:477-84. doi:10.1007/s10549-009-0415-0
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 477-484
-
-
Ogunleye, A.A.1
Xue, F.2
Michels, K.B.3
-
129
-
-
84866145433
-
Phase IB randomized, double-blinded, placebo-controlled, dose escalation study of polyphenon E in women with hormone receptor-negative breast cancer
-
doi:10.1158/1940-6207.CAPR-12-0117
-
Crew KD, Brown P, Greenlee H, Bevers TB, Arun B, Hudis C, et al. Phase IB randomized, double-blinded, placebo-controlled, dose escalation study of polyphenon E in women with hormone receptor-negative breast cancer. Cancer Prev Res (Phila) (2012) 5:1144-54. doi:10.1158/1940-6207.CAPR-12-0117
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 1144-1154
-
-
Crew, K.D.1
Brown, P.2
Greenlee, H.3
Bevers, T.B.4
Arun, B.5
Hudis, C.6
-
130
-
-
84871975530
-
Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice
-
doi:10.1186/1472-6882-13-6
-
Castillo-Pichardo L, Cubano LA, Dharmawardhane S. Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice. BMC Complement Altern Med (2013) 13:6. doi:10.1186/1472-6882-13-6
-
(2013)
BMC Complement Altern Med
, vol.13
, pp. 6
-
-
Castillo-Pichardo, L.1
Cubano, L.A.2
Dharmawardhane, S.3
-
131
-
-
84880036340
-
Regulatory effects of resveratrol on antioxidant enzymes: a mechanism of growth inhibition and apoptosis induction in cancer cells
-
doi:10.1007/s10059-013-2259-z
-
Khan MA, Chen HC, Wan XX, Tania M, Xu AH, Chen FZ, et al. Regulatory effects of resveratrol on antioxidant enzymes: a mechanism of growth inhibition and apoptosis induction in cancer cells. Mol Cells (2013) 35:219-25. doi:10.1007/s10059-013-2259-z
-
(2013)
Mol Cells
, vol.35
, pp. 219-225
-
-
Khan, M.A.1
Chen, H.C.2
Wan, X.X.3
Tania, M.4
Xu, A.H.5
Chen, F.Z.6
-
132
-
-
77956016499
-
Cancer prevention with natural compounds
-
doi:10.1053/j.seminoncol.2010.06.014
-
Gullett NP, Ruhul Amin AR, Bayraktar S, Pezzuto JM, Shin DM, Khuri FR, et al. Cancer prevention with natural compounds. Semin Oncol (2010) 37:258-81. doi:10.1053/j.seminoncol.2010.06.014
-
(2010)
Semin Oncol
, vol.37
, pp. 258-281
-
-
Gullett, N.P.1
Ruhul Amin, A.R.2
Bayraktar, S.3
Pezzuto, J.M.4
Shin, D.M.5
Khuri, F.R.6
-
133
-
-
84877639012
-
Cancer prevention and treatment using combination therapy with plant-and animal-derived compounds
-
doi:10.1586/ecp.12.62
-
Uzoigwe J, Sauter ER. Cancer prevention and treatment using combination therapy with plant-and animal-derived compounds. Expert Rev Clin Pharmacol (2012) 5:701-9. doi:10.1586/ecp.12.62
-
(2012)
Expert Rev Clin Pharmacol
, vol.5
, pp. 701-709
-
-
Uzoigwe, J.1
Sauter, E.R.2
|