메뉴 건너뛰기




Volumn 81, Issue , 2014, Pages 64-69

Recent insights into non-nuclear actions of estrogen receptor alpha

Author keywords

Bone mineralization; Caveolae; Endothelium; Estrogen receptor; Nitric oxide synthase; Vascular smooth muscle

Indexed keywords

26 HYDROXYCHOLESTEROL; CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR ALPHA; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE 2AC; PROTEIN KINASE B; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SPHINGOMYELIN; UNCLASSIFIED DRUG; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA, HUMAN; LIVER X RECEPTOR; ORPHAN NUCLEAR RECEPTOR;

EID: 84895546872     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2013.11.002     Document Type: Review
Times cited : (42)

References (58)
  • 1
    • 0025302288 scopus 로고
    • Steroid receptor family: Structure and functions
    • M.A. Carson-Jurica, W.T. Schrader, and B.W. O'Malley Steroid receptor family: structure and functions Endocr Rev 11 2 1990 201 220
    • (1990) Endocr Rev , vol.11 , Issue.2 , pp. 201-220
    • Carson-Jurica, M.A.1    Schrader, W.T.2    O'Malley, B.W.3
  • 2
    • 0023663885 scopus 로고
    • Functional domains of the human estrogen receptor
    • V. Kumar, S. Green, G. Stack, M. Berry, J.R. Jin, and P. Chambon Functional domains of the human estrogen receptor Cell 51 6 1987 941 951
    • (1987) Cell , vol.51 , Issue.6 , pp. 941-951
    • Kumar, V.1    Green, S.2    Stack, G.3    Berry, M.4    Jin, J.R.5    Chambon, P.6
  • 3
    • 37349081370 scopus 로고    scopus 로고
    • Extranuclear steroid receptors: Nature and actions
    • S.R. Hammes, and E.R. Levin Extranuclear steroid receptors: nature and actions Endocr Rev 28 7 2007 726 741
    • (2007) Endocr Rev , vol.28 , Issue.7 , pp. 726-741
    • Hammes, S.R.1    Levin, E.R.2
  • 4
    • 0345874610 scopus 로고    scopus 로고
    • Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model
    • A.W. Norman, M.T. Mizwicki, and D.P. Norman Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model Nat Rev Drug Discov 3 1 2004 27 41
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.1 , pp. 27-41
    • Norman, A.W.1    Mizwicki, M.T.2    Norman, D.P.3
  • 5
    • 0036798936 scopus 로고    scopus 로고
    • Estrogen modulation of endothelial nitric oxide synthase
    • K.L. Chambliss, and P.W. Shaul Estrogen modulation of endothelial nitric oxide synthase Endocr Rev 23 5 2002 665 686
    • (2002) Endocr Rev , vol.23 , Issue.5 , pp. 665-686
    • Chambliss, K.L.1    Shaul, P.W.2
  • 6
    • 15544379599 scopus 로고    scopus 로고
    • Estrogen-receptor biology: Continuing progress and therapeutic implications
    • C.K. Osborne, and R. Schiff Estrogen-receptor biology: continuing progress and therapeutic implications J Clin Oncol 23 8 2005 1616 1622
    • (2005) J Clin Oncol , vol.23 , Issue.8 , pp. 1616-1622
    • Osborne, C.K.1    Schiff, R.2
  • 7
    • 84881027754 scopus 로고    scopus 로고
    • Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation
    • K. Ueda, Q. Lu, W. Baur, M.J. Aronovitz, and R.H. Karas Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation Arterioscler Thromb Vasc Biol 33 8 2013 1837 1843
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.8 , pp. 1837-1843
    • Ueda, K.1    Lu, Q.2    Baur, W.3    Aronovitz, M.J.4    Karas, R.H.5
  • 8
    • 79955445707 scopus 로고    scopus 로고
    • Non-nuclear estrogen receptor signaling in the endothelium
    • Q. Wu, K. Chambliss, M. Umetani, C. Mineo, and P.W. Shaul Non-nuclear estrogen receptor signaling in the endothelium J Biol Chem 286 17 2011 14737 14743
    • (2011) J Biol Chem , vol.286 , Issue.17 , pp. 14737-14743
    • Wu, Q.1    Chambliss, K.2    Umetani, M.3    Mineo, C.4    Shaul, P.W.5
  • 9
    • 0030739144 scopus 로고    scopus 로고
    • Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium
    • R.L. Lantin-Hermoso, C.R. Rosenfeld, I.S. Yuhanna, Z. German, Z. Chen, and P.W. Shaul Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium Am J Physiol 273 1 Pt. 1 1997 L119 L126
    • (1997) Am J Physiol , vol.273 , Issue.PART 1
    • Lantin-Hermoso, R.L.1    Rosenfeld, C.R.2    Yuhanna, I.S.3    German, Z.4    Chen, Z.5    Shaul, P.W.6
  • 10
    • 0343247792 scopus 로고    scopus 로고
    • 17Beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization
    • T. Caulin-Glaser, G. Garcia-Cardena, P. Sarrel, W.C. Sessa, and J.R. Bender 17Beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization Circ Res 81 5 1997 885 892
    • (1997) Circ Res , vol.81 , Issue.5 , pp. 885-892
    • Caulin-Glaser, T.1    Garcia-Cardena, G.2    Sarrel, P.3    Sessa, W.C.4    Bender, J.R.5
  • 11
    • 33344476520 scopus 로고    scopus 로고
    • Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action
    • W.R. Harrington, S.H. Kim, C.C. Funk, Z. Madak-Erdogan, R. Schiff, and J.A. Katzenellenbogen et al. Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action Mol Endocrinol 20 3 2006 491 502
    • (2006) Mol Endocrinol , vol.20 , Issue.3 , pp. 491-502
    • Harrington, W.R.1    Kim, S.H.2    Funk, C.C.3    Madak-Erdogan, Z.4    Schiff, R.5    Katzenellenbogen, J.A.6
  • 12
    • 77955006975 scopus 로고    scopus 로고
    • Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice
    • K.L. Chambliss, Q. Wu, S. Oltmann, E.S. Konaniah, M. Umetani, and K.S. Korach et al. Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice J Clin Invest 120 7 2010 2319 2330
    • (2010) J Clin Invest , vol.120 , Issue.7 , pp. 2319-2330
    • Chambliss, K.L.1    Wu, Q.2    Oltmann, S.3    Konaniah, E.S.4    Umetani, M.5    Korach, K.S.6
  • 13
    • 0032589745 scopus 로고    scopus 로고
    • Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen
    • Z. Chen, I.S. Yuhanna, Z. Galcheva-Gargova, R.H. Karas, M.E. Mendelsohn, and P.W. Shaul Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen J Clin Invest 103 3 1999 401 406
    • (1999) J Clin Invest , vol.103 , Issue.3 , pp. 401-406
    • Chen, Z.1    Yuhanna, I.S.2    Galcheva-Gargova, Z.3    Karas, R.H.4    Mendelsohn, M.E.5    Shaul, P.W.6
  • 14
    • 4644264949 scopus 로고    scopus 로고
    • Estrogen induced changes in Akt-dependent activation of endothelial nitric oxide synthase and vasodilation
    • M. Florian, Y. Lu, M. Angle, and S. Magder Estrogen induced changes in Akt-dependent activation of endothelial nitric oxide synthase and vasodilation Steroids 69 10 2004 637 645
    • (2004) Steroids , vol.69 , Issue.10 , pp. 637-645
    • Florian, M.1    Lu, Y.2    Angle, M.3    Magder, S.4
  • 15
    • 21244506201 scopus 로고    scopus 로고
    • Estrogen induces vascular wall dilation: Mediation through kinase signaling to nitric oxide and estrogen receptors alpha and beta
    • X. Guo, M. Razandi, A. Pedram, G. Kassab, and E.R. Levin Estrogen induces vascular wall dilation: mediation through kinase signaling to nitric oxide and estrogen receptors alpha and beta J Biol Chem 280 20 2005 19704 19710
    • (2005) J Biol Chem , vol.280 , Issue.20 , pp. 19704-19710
    • Guo, X.1    Razandi, M.2    Pedram, A.3    Kassab, G.4    Levin, E.R.5
  • 16
    • 33747841976 scopus 로고    scopus 로고
    • Nature of functional estrogen receptors at the plasma membrane
    • A. Pedram, M. Razandi, and E.R. Levin Nature of functional estrogen receptors at the plasma membrane Mol Endocrinol 20 9 2006 1996 2009
    • (2006) Mol Endocrinol , vol.20 , Issue.9 , pp. 1996-2009
    • Pedram, A.1    Razandi, M.2    Levin, E.R.3
  • 17
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • T. Simoncini, A. Hafezi-Moghadam, D.P. Brazil, K. Ley, W.W. Chin, and J.K. Liao Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase Nature 407 6803 2000 538 541
    • (2000) Nature , vol.407 , Issue.6803 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 18
    • 0036199988 scopus 로고    scopus 로고
    • Regulation of endothelial nitric oxide synthase: Location, location, location
    • P.W. Shaul Regulation of endothelial nitric oxide synthase: location, location, location Annu Rev Physiol 64 2002 749 774
    • (2002) Annu Rev Physiol , vol.64 , pp. 749-774
    • Shaul, P.W.1
  • 19
    • 0034675994 scopus 로고    scopus 로고
    • Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
    • A. Migliaccio, G. Castoria, M. Di Domenico, A. de Falco, A. Bilancio, and M. Lombardi et al. Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation EMBO J 19 20 2000 5406 5417
    • (2000) EMBO J , vol.19 , Issue.20 , pp. 5406-5417
    • Migliaccio, A.1    Castoria, G.2    Di Domenico, M.3    De Falco, A.4    Bilancio, A.5    Lombardi, M.6
  • 20
    • 0037462671 scopus 로고    scopus 로고
    • Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen
    • M.P. Haynes, L. Li, D. Sinha, K.S. Russell, K. Hisamoto, and R. Baron et al. Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen J Biol Chem 278 4 2003 2118 2123
    • (2003) J Biol Chem , vol.278 , Issue.4 , pp. 2118-2123
    • Haynes, M.P.1    Li, L.2    Sinha, D.3    Russell, K.S.4    Hisamoto, K.5    Baron, R.6
  • 21
    • 36749003785 scopus 로고    scopus 로고
    • Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation
    • L. Li, K. Hisamoto, K.H. Kim, M.P. Haynes, P.M. Bauer, and A. Sanjay et al. Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation Proc Natl Acad Sci USA 104 42 2007 16468 16473
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.42 , pp. 16468-16473
    • Li, L.1    Hisamoto, K.2    Kim, K.H.3    Haynes, M.P.4    Bauer, P.M.5    Sanjay, A.6
  • 22
    • 0034711335 scopus 로고    scopus 로고
    • Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae
    • K.L. Chambliss, I.S. Yuhanna, C. Mineo, P. Liu, Z. German, and T.S. Sherman et al. Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae Circ Res 87 11 2000 E44 E52
    • (2000) Circ Res , vol.87 , Issue.11
    • Chambliss, K.L.1    Yuhanna, I.S.2    Mineo, C.3    Liu, P.4    German, Z.5    Sherman, T.S.6
  • 24
    • 0035920110 scopus 로고    scopus 로고
    • Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Galpha(i)
    • M.H. Wyckoff, K.L. Chambliss, C. Mineo, I.S. Yuhanna, M.E. Mendelsohn, and S.M. Mumby et al. Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Galpha(i) J Biol Chem 276 29 2001 27071 27076
    • (2001) J Biol Chem , vol.276 , Issue.29 , pp. 27071-27076
    • Wyckoff, M.H.1    Chambliss, K.L.2    Mineo, C.3    Yuhanna, I.S.4    Mendelsohn, M.E.5    Mumby, S.M.6
  • 25
    • 34250836804 scopus 로고    scopus 로고
    • Direct interactions with G alpha i and G beta gamma mediate nongenomic signaling by estrogen receptor alpha
    • P. Kumar, Q. Wu, K.L. Chambliss, I.S. Yuhanna, S.M. Mumby, and C. Mineo et al. Direct interactions with G alpha i and G beta gamma mediate nongenomic signaling by estrogen receptor alpha Mol Endocrinol 21 6 2007 1370 1380
    • (2007) Mol Endocrinol , vol.21 , Issue.6 , pp. 1370-1380
    • Kumar, P.1    Wu, Q.2    Chambliss, K.L.3    Yuhanna, I.S.4    Mumby, S.M.5    Mineo, C.6
  • 26
    • 17044455693 scopus 로고    scopus 로고
    • Cell-surface estrogen receptors mediate calcium-dependent nitric oxide release in human endothelia
    • G.B. Stefano, V. Prevot, J.C. Beauvillain, P. Cadet, C. Fimiani, and I. Welters et al. Cell-surface estrogen receptors mediate calcium-dependent nitric oxide release in human endothelia Circulation 101 13 2000 1594 1597
    • (2000) Circulation , vol.101 , Issue.13 , pp. 1594-1597
    • Stefano, G.B.1    Prevot, V.2    Beauvillain, J.C.3    Cadet, P.4    Fimiani, C.5    Welters, I.6
  • 28
    • 12344289207 scopus 로고    scopus 로고
    • Bovine serum albumin-estrogen compounds differentially alter gonadotropin-releasing hormone-1 neuronal activity
    • J.L. Temple, and S. Wray Bovine serum albumin-estrogen compounds differentially alter gonadotropin-releasing hormone-1 neuronal activity Endocrinology 146 2 2005 558 563
    • (2005) Endocrinology , vol.146 , Issue.2 , pp. 558-563
    • Temple, J.L.1    Wray, S.2
  • 29
    • 85047676039 scopus 로고    scopus 로고
    • 17Beta-estradiol increases intracellular calcium concentration through a short-term and nongenomic mechanism in rat vascular endothelium in culture
    • I. Rubio-Gayosso, A. Sierra-Ramirez, A. Garcia-Vazquez, A. Martinez-Martinez, O. Munoz-Garcia, and T. Morato et al. 17Beta-estradiol increases intracellular calcium concentration through a short-term and nongenomic mechanism in rat vascular endothelium in culture J Cardiovasc Pharmacol 36 2 2000 196 202
    • (2000) J Cardiovasc Pharmacol , vol.36 , Issue.2 , pp. 196-202
    • Rubio-Gayosso, I.1    Sierra-Ramirez, A.2    Garcia-Vazquez, A.3    Martinez-Martinez, A.4    Munoz-Garcia, O.5    Morato, T.6
  • 30
    • 0036488361 scopus 로고    scopus 로고
    • Endothelium-dependent effects of estrogen on vasomotor tone. Consequences of nongenomic actions
    • V.M. Miller, L. Li, and G.C. Sieck Endothelium-dependent effects of estrogen on vasomotor tone. Consequences of nongenomic actions Vascul Pharmacol 38 2 2002 109 113
    • (2002) Vascul Pharmacol , vol.38 , Issue.2 , pp. 109-113
    • Miller, V.M.1    Li, L.2    Sieck, G.C.3
  • 31
    • 0032981701 scopus 로고    scopus 로고
    • Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase
    • R.M. Goetz, H.S. Thatte, P. Prabhakar, M.R. Cho, T. Michel, and D.E. Golan Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase Proc Natl Acad Sci USA 96 6 1999 2788 2793
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.6 , pp. 2788-2793
    • Goetz, R.M.1    Thatte, H.S.2    Prabhakar, P.3    Cho, M.R.4    Michel, T.5    Golan, D.E.6
  • 32
    • 34447509229 scopus 로고    scopus 로고
    • Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells
    • T. Murata, M.I. Lin, R.V. Stan, P.M. Bauer, J. Yu, and W.C. Sessa Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells J Biol Chem 282 22 2007 16631 16643
    • (2007) J Biol Chem , vol.282 , Issue.22 , pp. 16631-16643
    • Murata, T.1    Lin, M.I.2    Stan, R.V.3    Bauer, P.M.4    Yu, J.5    Sessa, W.C.6
  • 33
    • 10344237581 scopus 로고    scopus 로고
    • Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha
    • Q. Lu, D.C. Pallas, H.K. Surks, W.E. Baur, M.E. Mendelsohn, and R.H. Karas Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha Proc Natl Acad Sci USA 101 49 2004 17126 17131
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.49 , pp. 17126-17131
    • Lu, Q.1    Pallas, D.C.2    Surks, H.K.3    Baur, W.E.4    Mendelsohn, M.E.5    Karas, R.H.6
  • 34
    • 84867574392 scopus 로고    scopus 로고
    • Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury
    • S.J. Bernelot Moens, G.R. Schnitzler, M. Nickerson, H. Guo, K. Ueda, and Q. Lu et al. Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury Circulation 126 16 2012 1993 2004
    • (2012) Circulation , vol.126 , Issue.16 , pp. 1993-2004
    • Bernelot Moens, S.J.1    Schnitzler, G.R.2    Nickerson, M.3    Guo, H.4    Ueda, K.5    Lu, Q.6
  • 35
    • 0030091218 scopus 로고    scopus 로고
    • Estradiol attenuates directed migration of vascular smooth muscle cells in vitro
    • F.D. Kolodgie, A. Jacob, P.S. Wilson, G.C. Carlson, A. Farb, and A. Verma et al. Estradiol attenuates directed migration of vascular smooth muscle cells in vitro Am J Pathol 148 3 1996 969 976
    • (1996) Am J Pathol , vol.148 , Issue.3 , pp. 969-976
    • Kolodgie, F.D.1    Jacob, A.2    Wilson, P.S.3    Carlson, G.C.4    Farb, A.5    Verma, A.6
  • 36
    • 0030948891 scopus 로고    scopus 로고
    • Estrogen reduces proliferation and agonist-induced calcium increase in coronary artery smooth muscle cells
    • R.C. Bhalla, K.F. Toth, R.A. Bhatty, L.P. Thompson, and R.V. Sharma Estrogen reduces proliferation and agonist-induced calcium increase in coronary artery smooth muscle cells Am J Physiol 272 4 Pt. 2 1997 H1996 H2003
    • (1997) Am J Physiol , vol.272 , Issue.PART 2
    • Bhalla, R.C.1    Toth, K.F.2    Bhatty, R.A.3    Thompson, L.P.4    Sharma, R.V.5
  • 37
    • 0037205290 scopus 로고    scopus 로고
    • Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury
    • G. Pare, A. Krust, R.H. Karas, S. Dupont, M. Aronovitz, and P. Chambon et al. Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury Circ Res 90 10 2002 1087 1092
    • (2002) Circ Res , vol.90 , Issue.10 , pp. 1087-1092
    • Pare, G.1    Krust, A.2    Karas, R.H.3    Dupont, S.4    Aronovitz, M.5    Chambon, P.6
  • 38
    • 33750489051 scopus 로고    scopus 로고
    • An inherent role of microtubule network in the action of nuclear receptor
    • B. Manavathi, F. Acconcia, S.K. Rayala, and R. Kumar An inherent role of microtubule network in the action of nuclear receptor Proc Natl Acad Sci USA 103 43 2006 15981 15986
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.43 , pp. 15981-15986
    • Manavathi, B.1    Acconcia, F.2    Rayala, S.K.3    Kumar, R.4
  • 39
    • 0036137605 scopus 로고    scopus 로고
    • Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation
    • R.X. Song, R.A. McPherson, L. Adam, Y. Bao, M. Shupnik, and R. Kumar et al. Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation Mol Endocrinol 16 1 2002 116 127
    • (2002) Mol Endocrinol , vol.16 , Issue.1 , pp. 116-127
    • Song, R.X.1    McPherson, R.A.2    Adam, L.3    Bao, Y.4    Shupnik, M.5    Kumar, R.6
  • 40
    • 2342470786 scopus 로고    scopus 로고
    • Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc
    • F. Barletta, C.W. Wong, C. McNally, B.S. Komm, B. Katzenellenbogen, and B.J. Cheskis Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc Mol Endocrinol 18 5 2004 1096 1108
    • (2004) Mol Endocrinol , vol.18 , Issue.5 , pp. 1096-1108
    • Barletta, F.1    Wong, C.W.2    McNally, C.3    Komm, B.S.4    Katzenellenbogen, B.5    Cheskis, B.J.6
  • 41
    • 0037371627 scopus 로고    scopus 로고
    • Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane
    • M. Razandi, G. Alton, A. Pedram, S. Ghonshani, P. Webb, and E.R. Levin Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane Mol Cell Biol 23 5 2003 1633 1646
    • (2003) Mol Cell Biol , vol.23 , Issue.5 , pp. 1633-1646
    • Razandi, M.1    Alton, G.2    Pedram, A.3    Ghonshani, S.4    Webb, P.5    Levin, E.R.6
  • 42
    • 0037446887 scopus 로고    scopus 로고
    • Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells
    • L. Li, M.P. Haynes, and J.R. Bender Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells Proc Natl Acad Sci USA 100 8 2003 4807 4812
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.8 , pp. 4807-4812
    • Li, L.1    Haynes, M.P.2    Bender, J.R.3
  • 44
    • 34547928773 scopus 로고    scopus 로고
    • A conserved mechanism for steroid receptor translocation to the plasma membrane
    • A. Pedram, M. Razandi, R.C. Sainson, J.K. Kim, C.C. Hughes, and E.R. Levin A conserved mechanism for steroid receptor translocation to the plasma membrane J Biol Chem 282 31 2007 22278 22288
    • (2007) J Biol Chem , vol.282 , Issue.31 , pp. 22278-22288
    • Pedram, A.1    Razandi, M.2    Sainson, R.C.3    Kim, J.K.4    Hughes, C.C.5    Levin, E.R.6
  • 45
    • 84860320810 scopus 로고    scopus 로고
    • Palmitoylation regulates 17beta-estradiol-induced estrogen receptor-alpha degradation and transcriptional activity
    • R.P. La, V. Pesiri, G. Leclercq, M. Marino, and F. Acconcia Palmitoylation regulates 17beta-estradiol-induced estrogen receptor-alpha degradation and transcriptional activity Mol Endocrinol 26 5 2012 762 774
    • (2012) Mol Endocrinol , vol.26 , Issue.5 , pp. 762-774
    • La, R.P.1    Pesiri, V.2    Leclercq, G.3    Marino, M.4    Acconcia, F.5
  • 46
    • 84871758853 scopus 로고    scopus 로고
    • Point mutations in the ERalpha Galphai binding domain segregate nonnuclear from nuclear receptor function
    • Q. Wu, K. Chambliss, W.R. Lee, I.S. Yuhanna, C. Mineo, and P.W. Shaul Point mutations in the ERalpha Galphai binding domain segregate nonnuclear from nuclear receptor function Mol Endocrinol 27 1 2013 2 11
    • (2013) Mol Endocrinol , vol.27 , Issue.1 , pp. 2-11
    • Wu, Q.1    Chambliss, K.2    Lee, W.R.3    Yuhanna, I.S.4    Mineo, C.5    Shaul, P.W.6
  • 47
    • 33751005875 scopus 로고    scopus 로고
    • Hormone-PAMAM dendrimer conjugates: Polymer dynamics and tether structure affect ligand access to receptors
    • S.H. Kim, and J.A. Katzenellenbogen Hormone-PAMAM dendrimer conjugates: polymer dynamics and tether structure affect ligand access to receptors Angew Chem Int Ed Engl 45 43 2006 7243 7248
    • (2006) Angew Chem Int Ed Engl , vol.45 , Issue.43 , pp. 7243-7248
    • Kim, S.H.1    Katzenellenbogen, J.A.2
  • 48
    • 34948820661 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
    • M. Umetani, H. Domoto, A.K. Gormley, I.S. Yuhanna, C.L. Cummins, and N.B. Javitt et al. 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen Nat Med 13 10 2007 1185 1192
    • (2007) Nat Med , vol.13 , Issue.10 , pp. 1185-1192
    • Umetani, M.1    Domoto, H.2    Gormley, A.K.3    Yuhanna, I.S.4    Cummins, C.L.5    Javitt, N.B.6
  • 49
    • 0038819062 scopus 로고    scopus 로고
    • Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
    • S. Kousteni, L. Han, J.R. Chen, M. Almeida, L.I. Plotkin, and T. Bellido et al. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids J Clin Invest 111 11 2003 1651 1664
    • (2003) J Clin Invest , vol.111 , Issue.11 , pp. 1651-1664
    • Kousteni, S.1    Han, L.2    Chen, J.R.3    Almeida, M.4    Plotkin, L.I.5    Bellido, T.6
  • 50
    • 0037174675 scopus 로고    scopus 로고
    • Reversal of bone loss in mice by nongenotropic signaling of sex steroids
    • S. Kousteni, J.R. Chen, T. Bellido, L. Han, A.A. Ali, and C.A. O'Brien et al. Reversal of bone loss in mice by nongenotropic signaling of sex steroids Science 298 5594 2002 843 846
    • (2002) Science , vol.298 , Issue.5594 , pp. 843-846
    • Kousteni, S.1    Chen, J.R.2    Bellido, T.3    Han, L.4    Ali, A.A.5    O'Brien, C.A.6
  • 51
    • 75149129597 scopus 로고    scopus 로고
    • From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis
    • S.C. Manolagas From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis Endocr Rev 31 3 2010 266 300
    • (2010) Endocr Rev , vol.31 , Issue.3 , pp. 266-300
    • Manolagas, S.C.1
  • 53
    • 84967614664 scopus 로고    scopus 로고
    • Sex steroids and the construction and conservation of the adult skeleton
    • B.L. Riggs, S. Khosla, and L.J. Melton III Sex steroids and the construction and conservation of the adult skeleton Endocr Rev 23 3 2002 279 302
    • (2002) Endocr Rev , vol.23 , Issue.3 , pp. 279-302
    • Riggs, B.L.1    Khosla, S.2    Melton III, L.J.3
  • 55
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways in cardiovascular disease
    • P. Tontonoz, and D.J. Mangelsdorf Liver X receptor signaling pathways in cardiovascular disease Mol Endocrinol 17 6 2003 985 993
    • (2003) Mol Endocrinol , vol.17 , Issue.6 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 56
    • 84881233906 scopus 로고    scopus 로고
    • LXRbeta/estrogen receptor-alpha signaling in lipid rafts preserves endothelial integrity
    • T. Ishikawa, I.S. Yuhanna, J. Umetani, W.R. Lee, K.S. Korach, and P.W. Shaul et al. LXRbeta/estrogen receptor-alpha signaling in lipid rafts preserves endothelial integrity J Clin Invest 123 8 2013 3488 3497
    • (2013) J Clin Invest , vol.123 , Issue.8 , pp. 3488-3497
    • Ishikawa, T.1    Yuhanna, I.S.2    Umetani, J.3    Lee, W.R.4    Korach, K.S.5    Shaul, P.W.6
  • 57
    • 33947625559 scopus 로고    scopus 로고
    • Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethylene glycol-modified polyamidoamine dendrimer
    • R.Q. Huang, Y.H. Qu, W.L. Ke, J.H. Zhu, Y.Y. Pei, and C. Jiang Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethylene glycol-modified polyamidoamine dendrimer FASEB J 21 4 2007 1117 1125
    • (2007) FASEB J , vol.21 , Issue.4 , pp. 1117-1125
    • Huang, R.Q.1    Qu, Y.H.2    Ke, W.L.3    Zhu, J.H.4    Pei, Y.Y.5    Jiang, C.6
  • 58
    • 70350200866 scopus 로고    scopus 로고
    • Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
    • W. Ke, K. Shao, R. Huang, L. Han, Y. Liu, and J. Li et al. Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer Biomaterials 30 36 2009 6976 6985
    • (2009) Biomaterials , vol.30 , Issue.36 , pp. 6976-6985
    • Ke, W.1    Shao, K.2    Huang, R.3    Han, L.4    Liu, Y.5    Li, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.