Atypical signaling and functional desensitization response of MAS receptor to peptide ligands

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Tirupula, Kalyan C ^a   Desnoyer, Russell ^a   Speth, Robert C ^b   Karnik, Sadashiva S ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NOVA SOUTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACLERASTIDE; ANGIOTENSIN DERIVATIVE; CALCIUM; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; LUCIFERASE; NEUROPEPTIDE FF; PHOSPHOLIPASE C; PROTEIN MAS; UNCLASSIFIED DRUG; ANGIOTENSIN I; ANGIOTENSIN I (1-7); LIGAND; NEUROPEPTIDE; OLIGOPEPTIDE; ONCOPROTEIN; PEPTIDE; PEPTIDE FRAGMENT; PHENYLALANYL-LEUCYL-PHENYLALANYL-GLUTAMINYL-PROLYL-GLUTAMINYL-ARGINYL-PHENYLALANINAMIDE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-MAS-1;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; RECEPTOR DOWN REGULATION; REPORTER GENE; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; INTRACELLULAR SPACE; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ANGIOTENSIN I; BINDING SITES; CALCIUM; HEK293 CELLS; HUMANS; INOSITOL PHOSPHATES; INTRACELLULAR SPACE; LIGANDS; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NEUROPEPTIDES; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84904864057     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103520     Document Type: Article

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