Discovery and validation of novel peptide agonists for G-protein-coupled receptors

Journal of Biological Chemistry

Volumn 283, Issue 50, 2008, Pages 34643-34649

  Shemesh, Ronen ^a   Toporik, Amir ^a   Levine, Zurit ^a   Hecht, Iris ^a   Rotman, Galit ^a   Wool, Assaf ^a   Dahary, Dvir ^a   Gofer, Eyal ^a   Kliger, Yossef ^a   Soffer, Michal Ayalon ^a   Rosenberg, Avi ^a   Eshel, Dani ^a   Cohen, Yossi ^a  

^a Compugen Limited ^*  (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CALCIUM; FETAL MONITORING; LEARNING ALGORITHMS; LEARNING SYSTEMS; PEPTIDES; PROTEINS;

COUPLED RECEPTORS; GPCRS ,; HUMAN GENOMES; HUMAN PROTEOME; IN VITRO; IN-VIVO; INTRACELLULAR CALCIUM MEASUREMENTS; MACHINE LEARNING ALGORITHMS; NATURAL LIGANDS; ORPHAN RECEPTORS; PEPTIDE LIGANDS; POTENTIAL DRUGS;

LIGANDS;

CALCIUM; CYCLIC AMP; FORMYLPEPTIDE RECEPTOR LIKE 1; G PROTEIN COUPLED RECEPTOR; PROTEIN P58; PROTEOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; COMPUTER MODEL; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MACHINE LEARNING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN TARGETING; VALIDATION STUDY;

ALGORITHMS; ANIMALS; COMPUTATIONAL BIOLOGY; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HUMANS; INFLAMMATION; LIGANDS; MICE; PEPTIDES; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEOMICS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 58049193594     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805181200     Document Type: Article

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