Interaction of biphenylimidazole and imidazoleacrylic acid nonpeptide antagonists with valine 108 in TM III of the AT1 angiotensin receptor

British Journal of Pharmacology

Volumn 119, Issue 8, 1996, Pages 1505-1507

  Nirula, Vaneet ^a   Zheng, Wei ^a   Sothinathan, Renuka ^a   Sandberg, Kathryn ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Angiotensin; Angiotensin receptors; Biphenylimidazoles; Imidazoleacrylic acids; Ligand binding; Nonpeptide antagonists; Site directed mutagenesis

Indexed keywords

3 [2' [(BUTOXYCARBONYL)AMINOSULFONYL] 5' (3 METHOXYBENZYL) 4 BIPHENYLYLMETHYL] 2 ETHYL 5,7 DIMETHYL 3H IMIDAZO[4,5 B]PYRIDINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; EPROSARTAN; IMIDAZOLE DERIVATIVE; L 162017; L 162313; L 162389; LOSARTAN; SB 203220; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BLOCKING;

EID: 0030466265     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16065.x     Document Type: Article

References (6)

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