-
1
-
-
0025286174
-
Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord
-
Aanonsen L.M., Lei S., and Wilcox G.L. Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord. Pain 41 (1990) 309-321
-
(1990)
Pain
, vol.41
, pp. 309-321
-
-
Aanonsen, L.M.1
Lei, S.2
Wilcox, G.L.3
-
2
-
-
0037172990
-
Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule
-
Bender E., Buist A., Jurzak M., Langlois X., Baggerman G., Verhasselt P., Ercken M., Guo H.Q., Wintmolders C., Van W.I., Van O.I., Schoofs L., and Luyten W. Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 8573-8578
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 8573-8578
-
-
Bender, E.1
Buist, A.2
Jurzak, M.3
Langlois, X.4
Baggerman, G.5
Verhasselt, P.6
Ercken, M.7
Guo, H.Q.8
Wintmolders, C.9
Van, W.I.10
Van, O.I.11
Schoofs, L.12
Luyten, W.13
-
3
-
-
0025011298
-
Localization of nitric oxide synthase indicating a neural role for nitric oxide
-
Bredt D.S., Hwang P.M., and Snyder S.H. Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 347 (1990) 768-770
-
(1990)
Nature
, vol.347
, pp. 768-770
-
-
Bredt, D.S.1
Hwang, P.M.2
Snyder, S.H.3
-
4
-
-
0028284167
-
Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type
-
Bunzow J.R., Saez C., Mortrud M., Bouvier C., Williams J.T., Low M., and Grandy D.K. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type. FEBS Lett. 347 (1994) 284-288
-
(1994)
FEBS Lett.
, vol.347
, pp. 284-288
-
-
Bunzow, J.R.1
Saez, C.2
Mortrud, M.3
Bouvier, C.4
Williams, J.T.5
Low, M.6
Grandy, D.K.7
-
5
-
-
34548309102
-
The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing
-
Cai M., Chen T., Quirion R., and Hong Y. The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing. Eur. J. Neurosci. 26 (2007) 1128-1138
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 1128-1138
-
-
Cai, M.1
Chen, T.2
Quirion, R.3
Hong, Y.4
-
6
-
-
23644438900
-
Structure-activity studies on different modifications of nociceptin/orphanin FQ: identification of highly potent agonists and antagonists of its receptor
-
Chang M., Peng Y.L., Dong S.L., Han R.W., Li W., Yang D.J., Chen Q., and Wang R. Structure-activity studies on different modifications of nociceptin/orphanin FQ: identification of highly potent agonists and antagonists of its receptor. Regul. Pept. 130 (2005) 116-122
-
(2005)
Regul. Pept.
, vol.130
, pp. 116-122
-
-
Chang, M.1
Peng, Y.L.2
Dong, S.L.3
Han, R.W.4
Li, W.5
Yang, D.J.6
Chen, Q.7
Wang, R.8
-
7
-
-
33746001396
-
Intrathecal sensory neuron-specific receptor agonists bovine adrenal medulla 8-22 and (Tyr6)-gamma2-MSH-6-12 inhibit formalin-evoked nociception and neuronal Fos-like immunoreactivity in the spinal cord of the rat
-
Chen T., Cai Q., and Hong Y. Intrathecal sensory neuron-specific receptor agonists bovine adrenal medulla 8-22 and (Tyr6)-gamma2-MSH-6-12 inhibit formalin-evoked nociception and neuronal Fos-like immunoreactivity in the spinal cord of the rat. Neuroscience 141 (2006) 965-975
-
(2006)
Neuroscience
, vol.141
, pp. 965-975
-
-
Chen, T.1
Cai, Q.2
Hong, Y.3
-
8
-
-
40849120477
-
Modulation of NMDA receptors by intrathecal administration of the sensory neuron-specific receptor agonist BAM8-22
-
Chen T., Hu Z., Quirion R., and Hong Y. Modulation of NMDA receptors by intrathecal administration of the sensory neuron-specific receptor agonist BAM8-22. Neuropharmacology 54 (2008) 796-803
-
(2008)
Neuropharmacology
, vol.54
, pp. 796-803
-
-
Chen, T.1
Hu, Z.2
Quirion, R.3
Hong, Y.4
-
9
-
-
0142092547
-
Adaptive evolution of MRG, a neuron-specific gene family implicated in nociception
-
Choi S.S., and Lahn B.T. Adaptive evolution of MRG, a neuron-specific gene family implicated in nociception. Genome Res. 13 (2003) 2252-2259
-
(2003)
Genome Res.
, vol.13
, pp. 2252-2259
-
-
Choi, S.S.1
Lahn, B.T.2
-
10
-
-
0027477465
-
Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence
-
Coderre T.J., Katz J., Vaccarino A.L., and Melzack R. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 52 (1993) 259-285
-
(1993)
Pain
, vol.52
, pp. 259-285
-
-
Coderre, T.J.1
Katz, J.2
Vaccarino, A.L.3
Melzack, R.4
-
11
-
-
3242727746
-
Evidence for an exclusive antinociceptive effect of nociceptin/orphanin FQ, an endogenous ligand for the ORL1 receptor, in two animal models of neuropathic pain
-
Courteix C., Coudore-Civiale M.A., Privat A.M., Pelissier T., Eschalier A., and Fialip J. Evidence for an exclusive antinociceptive effect of nociceptin/orphanin FQ, an endogenous ligand for the ORL1 receptor, in two animal models of neuropathic pain. Pain 110 (2004) 236-245
-
(2004)
Pain
, vol.110
, pp. 236-245
-
-
Courteix, C.1
Coudore-Civiale, M.A.2
Privat, A.M.3
Pelissier, T.4
Eschalier, A.5
Fialip, J.6
-
12
-
-
39449105335
-
The effect of deletion of the orphan G - protein coupled receptor (GPCR) gene MrgE on pain-like behaviours in mice
-
Cox P.J., Pitcher T., Trim S.A., Bell C.H., Qin W., and Kinloch R.A. The effect of deletion of the orphan G - protein coupled receptor (GPCR) gene MrgE on pain-like behaviours in mice. Mol. Pain 4 (2008) 2
-
(2008)
Mol. Pain
, vol.4
, pp. 2
-
-
Cox, P.J.1
Pitcher, T.2
Trim, S.A.3
Bell, C.H.4
Qin, W.5
Kinloch, R.A.6
-
13
-
-
0035822998
-
A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons
-
Dong X., Han S., Zylka M.J., Simon M.I., and Anderson D.J. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell 106 (2001) 619-632
-
(2001)
Cell
, vol.106
, pp. 619-632
-
-
Dong, X.1
Han, S.2
Zylka, M.J.3
Simon, M.I.4
Anderson, D.J.5
-
14
-
-
0142043854
-
Spinal delivery of analgesics in experimental models of pain and analgesia
-
Fairbanks C.A. Spinal delivery of analgesics in experimental models of pain and analgesia. Adv. Drug Deliv. Rev. 55 (2003) 1007-1041
-
(2003)
Adv. Drug Deliv. Rev.
, vol.55
, pp. 1007-1041
-
-
Fairbanks, C.A.1
-
15
-
-
0022501437
-
Nociceptive behavior after intrathecal injections of substance P, neurokinin A and calcitonin gene-related peptide in mice
-
Gamse R., and Saria A. Nociceptive behavior after intrathecal injections of substance P, neurokinin A and calcitonin gene-related peptide in mice. Neurosci. Lett. 70 (1986) 143-147
-
(1986)
Neurosci. Lett.
, vol.70
, pp. 143-147
-
-
Gamse, R.1
Saria, A.2
-
16
-
-
0026077959
-
Glutamate, nitric oxide and cell-cell signalling in the nervous system
-
Garthwaite J. Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14 (1991) 60-67
-
(1991)
Trends Neurosci.
, vol.14
, pp. 60-67
-
-
Garthwaite, J.1
-
17
-
-
0024296032
-
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
-
Garthwaite J., Charles S.L., and Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 336 (1988) 385-388
-
(1988)
Nature
, vol.336
, pp. 385-388
-
-
Garthwaite, J.1
Charles, S.L.2
Chess-Williams, R.3
-
18
-
-
2342621285
-
Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats
-
Grazzini E., Puma C., Roy M.O., Yu X.H., O'Donnell D., Schmidt R., Dautrey S., Ducharme J., Perkins M., Panetta R., Laird J.M., Ahmad S., and Lembo P.M. Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 7175-7180
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7175-7180
-
-
Grazzini, E.1
Puma, C.2
Roy, M.O.3
Yu, X.H.4
O'Donnell, D.5
Schmidt, R.6
Dautrey, S.7
Ducharme, J.8
Perkins, M.9
Panetta, R.10
Laird, J.M.11
Ahmad, S.12
Lembo, P.M.13
-
19
-
-
27844516042
-
Regulation of two rat mas-related genes in a model of neuropathic pain
-
Gustafson E.L., Maguire M., Campanella M., Tarozzo G., Jia Y., Dong X.W., Laverty M., Murgolo N., Priestley T., Reggiani A., Monsma F., and Beltramo M. Regulation of two rat mas-related genes in a model of neuropathic pain. Brain Res. Mol. Brain Res. 142 (2005) 58-64
-
(2005)
Brain Res. Mol. Brain Res.
, vol.142
, pp. 58-64
-
-
Gustafson, E.L.1
Maguire, M.2
Campanella, M.3
Tarozzo, G.4
Jia, Y.5
Dong, X.W.6
Laverty, M.7
Murgolo, N.8
Priestley, T.9
Reggiani, A.10
Monsma, F.11
Beltramo, M.12
-
20
-
-
37849014283
-
Morphological characterization of rat Mas-related G-protein-coupled receptor C and functional analysis of agonists
-
Hager U.A., Hein A., Lennerz J.K., Zimmermann K., Neuhuber W.L., and Reeh P.W. Morphological characterization of rat Mas-related G-protein-coupled receptor C and functional analysis of agonists. Neuroscience 151 (2008) 242-254
-
(2008)
Neuroscience
, vol.151
, pp. 242-254
-
-
Hager, U.A.1
Hein, A.2
Lennerz, J.K.3
Zimmermann, K.4
Neuhuber, W.L.5
Reeh, P.W.6
-
21
-
-
0037069391
-
Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway
-
Han S.K., Dong X., Hwang J.I., Zylka M.J., Anderson D.J., and Simon M.I. Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 14740-14745
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 14740-14745
-
-
Han, S.K.1
Dong, X.2
Hwang, J.I.3
Zylka, M.J.4
Anderson, D.J.5
Simon, M.I.6
-
22
-
-
0032104547
-
Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation
-
Hao J.X., Xu I.S., Wiesenfeld-Hallin Z., and Xu X.J. Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation. Pain 76 (1998) 385-393
-
(1998)
Pain
, vol.76
, pp. 385-393
-
-
Hao, J.X.1
Xu, I.S.2
Wiesenfeld-Hallin, Z.3
Xu, X.J.4
-
23
-
-
8244243943
-
Characterization of nociceptin hyperalgesia and allodynia in conscious mice
-
Hara N., Minami T., Okuda-Ashitaka E., Sugimoto T., Sakai M., Onaka M., Mori H., Imanishi T., Shingu K., and Ito S. Characterization of nociceptin hyperalgesia and allodynia in conscious mice. Br. J. Pharmacol. 121 (1997) 401-408
-
(1997)
Br. J. Pharmacol.
, vol.121
, pp. 401-408
-
-
Hara, N.1
Minami, T.2
Okuda-Ashitaka, E.3
Sugimoto, T.4
Sakai, M.5
Onaka, M.6
Mori, H.7
Imanishi, T.8
Shingu, K.9
Ito, S.10
-
24
-
-
34447523393
-
Sensitisation of TRPV1 in rat sensory neurones by activation of SNSRs
-
Honan S.A., and McNaughton P.A. Sensitisation of TRPV1 in rat sensory neurones by activation of SNSRs. Neurosci. Lett. 422 (2007) 1-6
-
(2007)
Neurosci. Lett.
, vol.422
, pp. 1-6
-
-
Honan, S.A.1
McNaughton, P.A.2
-
25
-
-
1542359654
-
Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain - potential function of a novel receptor
-
Hong Y., Dai P., Jiang J., and Zeng X. Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain - potential function of a novel receptor. Br. J. Pharmacol. 141 (2004) 423-430
-
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 423-430
-
-
Hong, Y.1
Dai, P.2
Jiang, J.3
Zeng, X.4
-
26
-
-
0018956018
-
Intrathecal morphine in mice: a new technique
-
Hylden J.L., and Wilcox G.L. Intrathecal morphine in mice: a new technique. Eur. J. Pharmacol. 67 (1980) 313-316
-
(1980)
Eur. J. Pharmacol.
, vol.67
, pp. 313-316
-
-
Hylden, J.L.1
Wilcox, G.L.2
-
27
-
-
0032842949
-
Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord
-
Inoue M., Shimohira I., Yoshida A., Zimmer A., Takeshima H., Sakurada T., and Ueda H. Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord. J. Pharmacol. Exp. Ther. 291 (1999) 308-313
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.291
, pp. 308-313
-
-
Inoue, M.1
Shimohira, I.2
Yoshida, A.3
Zimmer, A.4
Takeshima, H.5
Sakurada, T.6
Ueda, H.7
-
28
-
-
0037405722
-
In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord
-
Inoue M., Kawashima T., Takeshima H., Calo G., Inoue A., Nakata Y., and Ueda H. In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord. J. Pharmacol. Exp. Ther. 305 (2003) 495-501
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 495-501
-
-
Inoue, M.1
Kawashima, T.2
Takeshima, H.3
Calo, G.4
Inoue, A.5
Nakata, Y.6
Ueda, H.7
-
29
-
-
20144386808
-
Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides
-
Kamohara M., Matsuo A., Takasaki J., Kohda M., Matsumoto M., Matsumoto S., Soga T., Hiyama H., Kobori M., and Katou M. Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides. Biochem. Biophys. Res. Commun. 330 (2005) 1146-1152
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.330
, pp. 1146-1152
-
-
Kamohara, M.1
Matsuo, A.2
Takasaki, J.3
Kohda, M.4
Matsumoto, M.5
Matsumoto, S.6
Soga, T.7
Hiyama, H.8
Kobori, M.9
Katou, M.10
-
30
-
-
0031041294
-
Spinal analgesic activity of orphanin FQ/nociceptin and its fragments
-
King M.A., Rossi G.C., Chang A.H., Williams L., and Pasternak G.W. Spinal analgesic activity of orphanin FQ/nociceptin and its fragments. Neurosci. Lett. 223 (1997) 113-116
-
(1997)
Neurosci. Lett.
, vol.223
, pp. 113-116
-
-
King, M.A.1
Rossi, G.C.2
Chang, A.H.3
Williams, L.4
Pasternak, G.W.5
-
31
-
-
0026739958
-
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse
-
Kitto K.F., Haley J.E., and Wilcox G.L. Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse. Neurosci. Lett. 148 (1992) 1-5
-
(1992)
Neurosci. Lett.
, vol.148
, pp. 1-5
-
-
Kitto, K.F.1
Haley, J.E.2
Wilcox, G.L.3
-
32
-
-
0028349156
-
Nitric oxide synthases in mammals
-
Knowles R.G., and Moncada S. Nitric oxide synthases in mammals. Biochem. J. 298 Pt 2 (1994) 249-258
-
(1994)
Biochem. J.
, vol.298
, Issue.PART 2
, pp. 249-258
-
-
Knowles, R.G.1
Moncada, S.2
-
33
-
-
0027363622
-
Characterization of the role of spinal N-methyl-d-aspartate receptors in thermal nociception in the rat
-
Kolhekar R., Meller S.T., and Gebhart G.F. Characterization of the role of spinal N-methyl-d-aspartate receptors in thermal nociception in the rat. Neuroscience 57 (1993) 385-395
-
(1993)
Neuroscience
, vol.57
, pp. 385-395
-
-
Kolhekar, R.1
Meller, S.T.2
Gebhart, G.F.3
-
34
-
-
34047134223
-
Extracellular signal-regulated kinase (ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior
-
Komatsu T., Sakurada C., Sasaki M., Sanai K., Tsuzuki M., Bagetta G., Sakurada S., and Sakurada T. Extracellular signal-regulated kinase (ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior. Neuropharmacology 52 (2007) 1237-1243
-
(2007)
Neuropharmacology
, vol.52
, pp. 1237-1243
-
-
Komatsu, T.1
Sakurada, C.2
Sasaki, M.3
Sanai, K.4
Tsuzuki, M.5
Bagetta, G.6
Sakurada, S.7
Sakurada, T.8
-
35
-
-
0036180376
-
Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs
-
Lembo P.M., Grazzini E., Groblewski T., O'Donnell D., Roy M.O., Zhang J., Hoffert C., Cao J., Schmidt R., Pelletier M., Labarre M., Gosselin M., Fortin Y., Banville D., Shen S.H., Strom P., Payza K., Dray A., Walker P., and Ahmad S. Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs. Nat. Neurosci. 5 (2002) 201-209
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 201-209
-
-
Lembo, P.M.1
Grazzini, E.2
Groblewski, T.3
O'Donnell, D.4
Roy, M.O.5
Zhang, J.6
Hoffert, C.7
Cao, J.8
Schmidt, R.9
Pelletier, M.10
Labarre, M.11
Gosselin, M.12
Fortin, Y.13
Banville, D.14
Shen, S.H.15
Strom, P.16
Payza, K.17
Dray, A.18
Walker, P.19
Ahmad, S.20
more..
-
36
-
-
0027239945
-
Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats
-
Malmberg A.B., and Yaksh T.L. Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats. Pain 54 (1993) 291-300
-
(1993)
Pain
, vol.54
, pp. 291-300
-
-
Malmberg, A.B.1
Yaksh, T.L.2
-
37
-
-
0021944147
-
Characterization of the hyperalgesic effect induced by intrathecal injection of substance P
-
Matsumura H., Sakurada T., Hara A., Sakurada S., and Kisara K. Characterization of the hyperalgesic effect induced by intrathecal injection of substance P. Neuropharmacology 24 (1985) 421-426
-
(1985)
Neuropharmacology
, vol.24
, pp. 421-426
-
-
Matsumura, H.1
Sakurada, T.2
Hara, A.3
Sakurada, S.4
Kisara, K.5
-
38
-
-
0027502194
-
Nitric oxide (NO) and nociceptive processing in the spinal cord
-
Meller S.T., and Gebhart G.F. Nitric oxide (NO) and nociceptive processing in the spinal cord. Pain 52 (1993) 127-136
-
(1993)
Pain
, vol.52
, pp. 127-136
-
-
Meller, S.T.1
Gebhart, G.F.2
-
39
-
-
0026559148
-
Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-d-aspartate-produced facilitation of the nociceptive tail-flick reflex
-
Meller S.T., Dykstra C., and Gebhart G.F. Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-d-aspartate-produced facilitation of the nociceptive tail-flick reflex. Eur. J. Pharmacol. 214 (1992) 93-96
-
(1992)
Eur. J. Pharmacol.
, vol.214
, pp. 93-96
-
-
Meller, S.T.1
Dykstra, C.2
Gebhart, G.F.3
-
40
-
-
0026726106
-
Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat
-
Meller S.T., Pechman P.S., Gebhart G.F., and Maves T.J. Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat. Neuroscience 50 (1992) 7-10
-
(1992)
Neuroscience
, vol.50
, pp. 7-10
-
-
Meller, S.T.1
Pechman, P.S.2
Gebhart, G.F.3
Maves, T.J.4
-
41
-
-
0028361631
-
The role of nitric oxide in the development and maintenance of the hyperalgesia produced by intraplantar injection of carrageenan in the rat
-
Meller S.T., Cummings C.P., Traub R.J., and Gebhart G.F. The role of nitric oxide in the development and maintenance of the hyperalgesia produced by intraplantar injection of carrageenan in the rat. Neuroscience 60 (1994) 367-374
-
(1994)
Neuroscience
, vol.60
, pp. 367-374
-
-
Meller, S.T.1
Cummings, C.P.2
Traub, R.J.3
Gebhart, G.F.4
-
42
-
-
0030050543
-
Acute thermal hyperalgesia in the rat is produced by activation of N-methyl-d-aspartate receptors and protein kinase C and production of nitric oxide
-
Meller S.T., Dykstra C., and Gebhart G.F. Acute thermal hyperalgesia in the rat is produced by activation of N-methyl-d-aspartate receptors and protein kinase C and production of nitric oxide. Neuroscience 71 (1996) 327-335
-
(1996)
Neuroscience
, vol.71
, pp. 327-335
-
-
Meller, S.T.1
Dykstra, C.2
Gebhart, G.F.3
-
43
-
-
0027215472
-
Reduction of NMDA-induced behaviour after acute and chronic administration of desipramine in mice
-
Mjellem N., Lund A., and Hole K. Reduction of NMDA-induced behaviour after acute and chronic administration of desipramine in mice. Neuropharmacology 32 (1993) 591-595
-
(1993)
Neuropharmacology
, vol.32
, pp. 591-595
-
-
Mjellem, N.1
Lund, A.2
Hole, K.3
-
44
-
-
0027752805
-
The l-arginine-nitric oxide pathway
-
Moncada S., and Higgs A. The l-arginine-nitric oxide pathway. N. Engl. J. Med. 329 (1993) 2002-2012
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 2002-2012
-
-
Moncada, S.1
Higgs, A.2
-
45
-
-
0021277125
-
Hyperalgesia produced by intrathecal substance P and related peptides: desensitization and cross desensitization
-
Moochhala S.M., and Sawynok J. Hyperalgesia produced by intrathecal substance P and related peptides: desensitization and cross desensitization. Br. J. Pharmacol. 82 (1984) 381-388
-
(1984)
Br. J. Pharmacol.
, vol.82
, pp. 381-388
-
-
Moochhala, S.M.1
Sawynok, J.2
-
46
-
-
0025922196
-
L-NG-nitro arginine methyl ester exhibits antinociceptive activity in the mouse
-
Moore P.K., Oluyomi A.O., Babbedge R.C., Wallace P., and Hart S.L. L-NG-nitro arginine methyl ester exhibits antinociceptive activity in the mouse. Br. J. Pharmacol. 102 (1991) 198-202
-
(1991)
Br. J. Pharmacol.
, vol.102
, pp. 198-202
-
-
Moore, P.K.1
Oluyomi, A.O.2
Babbedge, R.C.3
Wallace, P.4
Hart, S.L.5
-
47
-
-
0026078084
-
Effect of neurokinin A, substance P and calcitonin gene related peptide in peripheral hyperalgesia in the rat paw
-
Nakamura-Craig M., and Gill B.K. Effect of neurokinin A, substance P and calcitonin gene related peptide in peripheral hyperalgesia in the rat paw. Neurosci. Lett. 124 (1991) 49-51
-
(1991)
Neurosci. Lett.
, vol.124
, pp. 49-51
-
-
Nakamura-Craig, M.1
Gill, B.K.2
-
48
-
-
33846813597
-
UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ: behavioral and electrophysiological studies in mice
-
Nazzaro C., Rizzi A., Salvadori S., Guerrini R., Regoli D., Zeilhofer H.U., and Calo G. UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ: behavioral and electrophysiological studies in mice. Peptides 28 (2007) 663-669
-
(2007)
Peptides
, vol.28
, pp. 663-669
-
-
Nazzaro, C.1
Rizzi, A.2
Salvadori, S.3
Guerrini, R.4
Regoli, D.5
Zeilhofer, H.U.6
Calo, G.7
-
50
-
-
33646177255
-
2 of nociceptin/orphanin FQ receptor
-
2 of nociceptin/orphanin FQ receptor. Regul. Pept. 134 (2006) 75-81
-
(2006)
Regul. Pept.
, vol.134
, pp. 75-81
-
-
Peng, Y.L.1
Chang, M.2
Dong, S.L.3
Li, W.4
Han, R.W.5
Fu, G.X.6
Chen, Q.7
Wang, R.8
-
51
-
-
0023271762
-
Intrathecal N-methyl-d-aspartate (NMDA) activates both nociceptive and antinociceptive systems
-
Raigorodsky G., and Urca G. Intrathecal N-methyl-d-aspartate (NMDA) activates both nociceptive and antinociceptive systems. Brain Res. 422 (1987) 158-162
-
(1987)
Brain Res.
, vol.422
, pp. 158-162
-
-
Raigorodsky, G.1
Urca, G.2
-
52
-
-
0029767435
-
Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord
-
Riedl M., Shuster S., Vulchanova L., Wang J., Loh H.H., and Elde R. Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord. NeuroReport 7 (1996) 1369-1372
-
(1996)
NeuroReport
, vol.7
, pp. 1369-1372
-
-
Riedl, M.1
Shuster, S.2
Vulchanova, L.3
Wang, J.4
Loh, H.H.5
Elde, R.6
-
53
-
-
33746812739
-
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences
-
Rizzi A., Nazzaro C., Marzola G.G., Zucchini S., Trapella C., Guerrini R., Zeilhofer H.U., Regoli D., and Calo' G. Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences. Pain 124 (2006) 100-108
-
(2006)
Pain
, vol.124
, pp. 100-108
-
-
Rizzi, A.1
Nazzaro, C.2
Marzola, G.G.3
Zucchini, S.4
Trapella, C.5
Guerrini, R.6
Zeilhofer, H.U.7
Regoli, D.8
Calo', G.9
-
54
-
-
0242666360
-
MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion
-
Robas N., Mead E., and Fidock M. MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion. J. Biol. Chem. 278 (2003) 44400-44404
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44400-44404
-
-
Robas, N.1
Mead, E.2
Fidock, M.3
-
55
-
-
0025184549
-
The effects of substance P analogues on the scratching, biting and licking response induced by intrathecal injection of N-methyl-d-aspartate in mice
-
Sakurada T., Manome Y., Tan-No K., Sakurada S., and Kisara K. The effects of substance P analogues on the scratching, biting and licking response induced by intrathecal injection of N-methyl-d-aspartate in mice. Br. J. Pharmacol. 101 (1990) 307-310
-
(1990)
Br. J. Pharmacol.
, vol.101
, pp. 307-310
-
-
Sakurada, T.1
Manome, Y.2
Tan-No, K.3
Sakurada, S.4
Kisara, K.5
-
56
-
-
0030245813
-
Involvement of nitric oxide in spinally mediated capsaicin- and glutamate-induced behavioural responses in the mouse
-
Sakurada T., Sugiyama A., Sakurada C., Tanno K., Sakurada S., Kisara K., Hara A., and Abiko Y. Involvement of nitric oxide in spinally mediated capsaicin- and glutamate-induced behavioural responses in the mouse. Neurochem. Int. 29 (1996) 271-278
-
(1996)
Neurochem. Int.
, vol.29
, pp. 271-278
-
-
Sakurada, T.1
Sugiyama, A.2
Sakurada, C.3
Tanno, K.4
Sakurada, S.5
Kisara, K.6
Hara, A.7
Abiko, Y.8
-
58
-
-
0032810815
-
1 receptors
-
1 receptors. Br. J. Pharmacol. 127 (1999) 1712-1718
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 1712-1718
-
-
Sakurada, T.1
Katsuyama, S.2
Sakurada, S.3
Inoue, M.4
Tan-No, K.5
Kisara, K.6
Sakurada, C.7
Ueda, H.8
Sasaki, J.9
-
59
-
-
0037005745
-
Possible involvement of tachykinin NK(1) and NMDA receptors in histamine-induced hyperalgesia in mice
-
Sakurada S., Orito T., Sakurada C., Sato T., Hayashi T., Mobarakeh J.I., Yanai K., Onodera K., Watanabe T., and Sakurada T. Possible involvement of tachykinin NK(1) and NMDA receptors in histamine-induced hyperalgesia in mice. Eur. J. Pharmacol. 434 (2002) 29-34
-
(2002)
Eur. J. Pharmacol.
, vol.434
, pp. 29-34
-
-
Sakurada, S.1
Orito, T.2
Sakurada, C.3
Sato, T.4
Hayashi, T.5
Mobarakeh, J.I.6
Yanai, K.7
Onodera, K.8
Watanabe, T.9
Sakurada, T.10
-
60
-
-
0037203852
-
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors
-
Sakurada T., Watanabe C., Okuda K., Sugiyama A., Moriyama T., Sakurada C., Tan-No K., and Sakurada S. Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors. Brain Res. Mol. Brain Res. 98 (2002) 111-118
-
(2002)
Brain Res. Mol. Brain Res.
, vol.98
, pp. 111-118
-
-
Sakurada, T.1
Watanabe, C.2
Okuda, K.3
Sugiyama, A.4
Moriyama, T.5
Sakurada, C.6
Tan-No, K.7
Sakurada, S.8
-
61
-
-
5644292376
-
Involvement of the histaminergic system in the nociceptin-induced pain-related behaviors in the mouse spinal cord
-
Sakurada S., Watanabe H., Mizoguchi H., Yonezawa A., Orito T., Katsuyama S., Kuramasu A., Sakurada C., Yanai K., and Sakurada T. Involvement of the histaminergic system in the nociceptin-induced pain-related behaviors in the mouse spinal cord. Pain 112 (2004) 171-182
-
(2004)
Pain
, vol.112
, pp. 171-182
-
-
Sakurada, S.1
Watanabe, H.2
Mizoguchi, H.3
Yonezawa, A.4
Orito, T.5
Katsuyama, S.6
Kuramasu, A.7
Sakurada, C.8
Yanai, K.9
Sakurada, T.10
-
62
-
-
26444539532
-
Mechanisms of nociception evoked by intrathecal high-dose morphine
-
Sakurada T., Komatsu T., and Sakurada S. Mechanisms of nociception evoked by intrathecal high-dose morphine. Neurotoxicology 26 (2005) 801-809
-
(2005)
Neurotoxicology
, vol.26
, pp. 801-809
-
-
Sakurada, T.1
Komatsu, T.2
Sakurada, S.3
-
63
-
-
0030218947
-
The nitric oxide-cyclic GMP pathway is required for nociceptive signalling at specific loci within the somatosensory pathway
-
Salter M., Strijbos P.J., Neale S., Duffy C., Follenfant R.L., and Garthwaite J. The nitric oxide-cyclic GMP pathway is required for nociceptive signalling at specific loci within the somatosensory pathway. Neuroscience 73 (1996) 649-655
-
(1996)
Neuroscience
, vol.73
, pp. 649-655
-
-
Salter, M.1
Strijbos, P.J.2
Neale, S.3
Duffy, C.4
Follenfant, R.L.5
Garthwaite, J.6
-
64
-
-
0027433726
-
Afferent and spinal mechanisms of joint pain
-
Schaible H.G., and Grubb B.D. Afferent and spinal mechanisms of joint pain. Pain 55 (1993) 5-54
-
(1993)
Pain
, vol.55
, pp. 5-54
-
-
Schaible, H.G.1
Grubb, B.D.2
-
65
-
-
0030901503
-
Determination of nociceptin-like immunoreactivity in the rat dorsal spinal cord
-
Schuligoi R., Amann R., Angelberger P., and Peskar B.A. Determination of nociceptin-like immunoreactivity in the rat dorsal spinal cord. Neurosci. Lett. 224 (1997) 136-138
-
(1997)
Neurosci. Lett.
, vol.224
, pp. 136-138
-
-
Schuligoi, R.1
Amann, R.2
Angelberger, P.3
Peskar, B.A.4
-
66
-
-
0030454376
-
Nociceptin/orphanin FQ and opioid peptides show overlapping distribution but not co-localization in pain-modulatory brain regions
-
Schulz S., Schreff M., Nuss D., Gramsch C., and Hollt V. Nociceptin/orphanin FQ and opioid peptides show overlapping distribution but not co-localization in pain-modulatory brain regions. NeuroReport 7 (1996) 3021-3025
-
(1996)
NeuroReport
, vol.7
, pp. 3021-3025
-
-
Schulz, S.1
Schreff, M.2
Nuss, D.3
Gramsch, C.4
Hollt, V.5
-
67
-
-
2542437000
-
Identification of a G protein-coupled receptor specifically responsive to beta-alanine
-
Shinohara T., Harada M., Ogi K., Maruyama M., Fujii R., Tanaka H., Fukusumi S., Komatsu H., Hosoya M., Noguchi Y., Watanabe T., Moriya T., Itoh Y., and Hinuma S. Identification of a G protein-coupled receptor specifically responsive to beta-alanine. J. Biol. Chem. 279 (2004) 23559-23564
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23559-23564
-
-
Shinohara, T.1
Harada, M.2
Ogi, K.3
Maruyama, M.4
Fujii, R.5
Tanaka, H.6
Fukusumi, S.7
Komatsu, H.8
Hosoya, M.9
Noguchi, Y.10
Watanabe, T.11
Moriya, T.12
Itoh, Y.13
Hinuma, S.14
-
68
-
-
0023635234
-
Behavioural characterization of substance P-induced nociceptive response in mice
-
Takahasi K., Sakurada T., Sakurada S., Kuwahara H., Yonezawa A., Ando R., and Kisara K. Behavioural characterization of substance P-induced nociceptive response in mice. Neuropharmacology 26 (1987) 1289-1293
-
(1987)
Neuropharmacology
, vol.26
, pp. 1289-1293
-
-
Takahasi, K.1
Sakurada, T.2
Sakurada, S.3
Kuwahara, H.4
Yonezawa, A.5
Ando, R.6
Kisara, K.7
-
69
-
-
0034194879
-
Intrathecally administered spermine produces the scratching, biting and licking behaviour in mice
-
Tan-No K., Taira A., Wako K., Niijima F., Nakagawasai O., Tadano T., Sakurada C., Sakurada T., and Kisara K. Intrathecally administered spermine produces the scratching, biting and licking behaviour in mice. Pain 86 (2000) 55-61
-
(2000)
Pain
, vol.86
, pp. 55-61
-
-
Tan-No, K.1
Taira, A.2
Wako, K.3
Niijima, F.4
Nakagawasai, O.5
Tadano, T.6
Sakurada, C.7
Sakurada, T.8
Kisara, K.9
-
70
-
-
0037064235
-
Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-d-aspartate receptor mechanism
-
Tan-No K., Esashi A., Nakagawasai O., Niijima F., Tadano T., Sakurada C., Sakurada T., Bakalkin G., Terenius L., and Kisara K. Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-d-aspartate receptor mechanism. Brain Res. 952 (2002) 7-14
-
(2002)
Brain Res.
, vol.952
, pp. 7-14
-
-
Tan-No, K.1
Esashi, A.2
Nakagawasai, O.3
Niijima, F.4
Tadano, T.5
Sakurada, C.6
Sakurada, T.7
Bakalkin, G.8
Terenius, L.9
Kisara, K.10
-
71
-
-
1842815269
-
Nociceptive behavior induced by poly-l-lysine and other basic compounds involves the spinal NMDA receptors
-
Tan-No K., Esashi A., Nakagawasai O., Niijima F., Sakurada C., Sakurada T., Bakalkin G., Terenius L., and Tadano T. Nociceptive behavior induced by poly-l-lysine and other basic compounds involves the spinal NMDA receptors. Brain Res. 1008 (2004) 49-53
-
(2004)
Brain Res.
, vol.1008
, pp. 49-53
-
-
Tan-No, K.1
Esashi, A.2
Nakagawasai, O.3
Niijima, F.4
Sakurada, C.5
Sakurada, T.6
Bakalkin, G.7
Terenius, L.8
Tadano, T.9
-
72
-
-
0033036741
-
In vivo pathway of thermal hyperalgesia by intrathecal administration of alpha,beta-methylene ATP in mouse spinal cord: involvement of the glutamate-NMDA receptor system
-
Tsuda M., Ueno S., and Inoue K. In vivo pathway of thermal hyperalgesia by intrathecal administration of alpha,beta-methylene ATP in mouse spinal cord: involvement of the glutamate-NMDA receptor system. Br. J. Pharmacol. 127 (1999) 449-456
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 449-456
-
-
Tsuda, M.1
Ueno, S.2
Inoue, K.3
-
73
-
-
0023726747
-
Behavioral classification of excitatory amino acid receptors in mouse spinal cord
-
Urca G., and Raigorodsky G. Behavioral classification of excitatory amino acid receptors in mouse spinal cord. Eur. J. Pharmacol. 153 (1988) 211-220
-
(1988)
Eur. J. Pharmacol.
, vol.153
, pp. 211-220
-
-
Urca, G.1
Raigorodsky, G.2
-
75
-
-
33646883475
-
Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1
-
Wang Z., Takahashi T., Saito Y., Nagasaki H., Ly N.K., Nothacker H.P., Reinscheid R.K., Yang J., Chang J.K., Shichiri M., and Civelli O. Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1. Eur. J. Pharmacol. 539 (2006) 145-150
-
(2006)
Eur. J. Pharmacol.
, vol.539
, pp. 145-150
-
-
Wang, Z.1
Takahashi, T.2
Saito, Y.3
Nagasaki, H.4
Ly, N.K.5
Nothacker, H.P.6
Reinscheid, R.K.7
Yang, J.8
Chang, J.K.9
Shichiri, M.10
Civelli, O.11
-
76
-
-
38549126603
-
Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors
-
Watanabe C., Orito T., Watanabe H., Mizoguchi H., Yonezawa A., Yanai K., Mobarakeh J.I., Onodera K., Sakurada T., and Sakurada S. Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors. Eur. J. Pharmacol. 581 (2008) 54-63
-
(2008)
Eur. J. Pharmacol.
, vol.581
, pp. 54-63
-
-
Watanabe, C.1
Orito, T.2
Watanabe, H.3
Mizoguchi, H.4
Yonezawa, A.5
Yanai, K.6
Mobarakeh, J.I.7
Onodera, K.8
Sakurada, T.9
Sakurada, S.10
-
77
-
-
0029121976
-
Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines
-
Wick M.J., Minnerath S.R., Roy S., Ramakrishnan S., and Loh H.H. Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines. Brain Res. Mol. Brain Res. 32 (1995) 342-347
-
(1995)
Brain Res. Mol. Brain Res.
, vol.32
, pp. 342-347
-
-
Wick, M.J.1
Minnerath, S.R.2
Roy, S.3
Ramakrishnan, S.4
Loh, H.H.5
-
78
-
-
0021750080
-
Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat
-
Wiesenfeld-Hallin Z., Hokfelt T., Lundberg J.M., Forssmann W.G., Reinecke M., Tschopp F.A., and Fischer J.A. Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat. Neurosci. Lett. 52 (1984) 199-204
-
(1984)
Neurosci. Lett.
, vol.52
, pp. 199-204
-
-
Wiesenfeld-Hallin, Z.1
Hokfelt, T.2
Lundberg, J.M.3
Forssmann, W.G.4
Reinecke, M.5
Tschopp, F.A.6
Fischer, J.A.7
-
79
-
-
0029806549
-
Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat
-
Xu X.J., Hao J.X., and Wiesenfeld-Hallin Z. Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat. NeuroReport 7 (1996) 2092-2094
-
(1996)
NeuroReport
, vol.7
, pp. 2092-2094
-
-
Xu, X.J.1
Hao, J.X.2
Wiesenfeld-Hallin, Z.3
-
80
-
-
0030830192
-
Analgesic effect of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, in the rat formalin test
-
Yamamoto T., Nozaki-Taguchi N., and Kimura S. Analgesic effect of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, in the rat formalin test. Neuroscience 81 (1997) 249-254
-
(1997)
Neuroscience
, vol.81
, pp. 249-254
-
-
Yamamoto, T.1
Nozaki-Taguchi, N.2
Kimura, S.3
-
81
-
-
0038298252
-
Nociceptin/orphanin FQ and its receptor-potential targets for pain therapy?
-
Zeilhofer H.U., and Calo G. Nociceptin/orphanin FQ and its receptor-potential targets for pain therapy?. J. Pharmacol. Exp. Ther. 306 (2003) 423-429
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 423-429
-
-
Zeilhofer, H.U.1
Calo, G.2
-
82
-
-
7444261339
-
Effects of intrathecal BAM22 on noxious stimulus-evoked c-fos expression in the rat spinal dorsal horn
-
Zeng X., Huang H., and Hong Y. Effects of intrathecal BAM22 on noxious stimulus-evoked c-fos expression in the rat spinal dorsal horn. Brain Res. 1028 (2004) 170-179
-
(2004)
Brain Res.
, vol.1028
, pp. 170-179
-
-
Zeng, X.1
Huang, H.2
Hong, Y.3
-
83
-
-
0043192823
-
Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family
-
Zylka M.J., Dong X., Southwell A.L., and Anderson D.J. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 10043-10048
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 10043-10048
-
-
Zylka, M.J.1
Dong, X.2
Southwell, A.L.3
Anderson, D.J.4
|