Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine

Journal of Biological Chemistry

Volumn 288, Issue 18, 2013, Pages 12818-12827

  Than, Jonathan Y X L ^a   Li, Lin ^a   Hasan, Raquibul ^a   Zhang, Xuming ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHANNEL BLOCKERS; DORSAL ROOT GANGLION NEURONS; PHOSPHOLIPASE C; PHOSPHOLIPASES; SENSORY NEURONS; TRANSIENT RECEPTOR POTENTIALS;

HEALTH;

NEURONS;

CHLOROQUINE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; PHOSPHOLIPASE C; PROTEIN KINASE C; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; VANILLOID RECEPTOR 1;

ANIMAL CELL; ARTICLE; COLD SENSATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NERVE CELL EXCITABILITY; NEUROMODULATION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PAIN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PRURITUS; SENSITIZATION; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION;

CALCIUM IMAGING; CHLOROQUINE; ELECTROPHYSIOLOGY; G PROTEIN-COUPLED RECEPTOR (GPCR); ITCH; PAIN; SENSORY TRANSDUCTION; SIGNAL TRANSDUCTION; TRP CHANNELS;

ACETANILIDES; AMEBICIDES; ANILIDES; ANIMALS; CHLOROQUINE; GANGLIA, SPINAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HUMANS; MICE; PURINES; PYRAZOLES; SENSATION; SENSORY RECEPTOR CELLS; THIADIAZOLES; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPM CATION CHANNELS; TRPV CATION CHANNELS; TYPE C PHOSPHOLIPASES;

EID: 84877143340     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.450072     Document Type: Article

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