Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Manikkam, Mohan ^a   Haque, M Muksitul ^a   Guerrero Bosagna, Carlos ^a   Nilsson, Eric E ^a   Skinner, Michael K ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHOXYCHLOR; INSECTICIDE;

ADULT; ADULT ONSET DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE TRANSMISSION; DNA METHYLATION; DNA STRUCTURE; ENVIRONMENTAL EXPOSURE; EPIGENETIC TRANSGENERATIONAL INHERITANCE; EPIGENETICS; EPIMUTATION; FEMALE; FEMALE GERMLINE; GENERAL ASPECTS OF DISEASE; GENETIC ASSOCIATION; GERM LINE; GONAD DEVELOPMENT; HISTOPATHOLOGY; INCIDENCE; INHERITANCE; KIDNEY DISEASE; MALE; METRITIS; MOLECULAR DYNAMICS; NONHUMAN; OBESITY; OUTCROSSING; OVARY DISEASE; OVARY POLYCYSTIC DISEASE; PROGENY; PROMOTER REGION; PUBERTY DISORDERS; RAT; ANIMAL; DRUG EFFECTS; FETUS; GENETIC EPIGENESIS; GENETICS; GENOME; GROWTH, DEVELOPMENT AND AGING; KIDNEY; METABOLISM; OVARY; OVUM; PATHOLOGY; SEX DETERMINATION PROCESS; SPERMATOZOON; SPRAGUE DAWLEY RAT;

ANIMALS; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENESIS, GENETIC; FEMALE; FETUS; GENOME; INHERITANCE PATTERNS; INSECTICIDES; KIDNEY; MALE; METHOXYCHLOR; OBESITY; OVARY; OVUM; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; SEX DETERMINATION PROCESSES; SPERMATOZOA;

EID: 84904793407     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102091     Document Type: Article

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