Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Xu, Ning ^a   Kwon, Soonil ^a   Abbott, David H ^b   Geller, David H ^a   Dumesic, Daniel A ^b,c   Azziz, Ricardo ^a,d   Guo, Xiuqing ^a   Goodarzi, Mark O ^a,c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRIZZLED PROTEIN; INSULIN; PROTEIN; PROTEIN TOB; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA3; TESTOSTERONE; UNCLASSIFIED DRUG; ANDROGEN; TRANSFORMING GROWTH FACTOR BETA;

ADIPOGENESIS; ANDROGEN RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DISEASE PREDISPOSITION; DNA METHYLATION; DNA PROBE; FEMALE; GENE; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC EPIGENESIS; GENETIC VARIABILITY; INSULIN BLOOD LEVEL; INTRAABDOMINAL FAT; INTRACELLULAR SIGNALING; MORPHOLOGICAL TRAIT; NONHUMAN; OVARY POLYCYSTIC DISEASE; PATHOPHYSIOLOGY; PHENOTYPE; RHESUS MONKEY; TESTOSTERONE BLOOD LEVEL; TIGHT JUNCTION; TOB GENE; ANIMAL; BAYES THEOREM; COMPARATIVE STUDY; GONADAL DISEASE; MACACA MULATTA; METABOLISM; NEWBORN; PATHOLOGY; PILOT STUDY; PREGNANCY; PREGNANCY COMPLICATION; PRENATAL EXPOSURE; SIGNAL TRANSDUCTION;

MACACA MULATTA; PRIMATES;

ANDROGENS; ANIMALS; ANIMALS, NEWBORN; BAYES THEOREM; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; INTRA-ABDOMINAL FAT; MACACA MULATTA; PILOT PROJECTS; POLYCYSTIC OVARY SYNDROME; PREGNANCY; PREGNANCY COMPLICATIONS, NEOPLASTIC; PRENATAL EXPOSURE DELAYED EFFECTS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; VIRILISM;

EID: 80455156236     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027286     Document Type: Article

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