A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1- trichloroethane, reduces testosterone biosynthesis in rat Leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme

Biology of Reproduction

Volumn 62, Issue 3, 2000, Pages 571-578

  Akingbemi, Benson T ^a   Ge, Ren Shan ^a   Klinefelter, Gary R ^b   Gunsalus, Glen L ^a   Hardy, Matthew P ^a  

^a POPULATION COUNCIL   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; BUCLADESINE; CHLORPHENOTANE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); LUTEINIZING HORMONE; MESSENGER RNA; METHOXYCHLOR; PESTICIDE; PREGNENOLONE; PROGESTERONE; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; INFERTILITY; LEYDIG CELL; MALE; MALE INFERTILITY; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEADY STATE; STEROIDOGENESIS; TESTOSTERONE SYNTHESIS;

ANIMALIA;

EID: 0034003004     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod62.3.571     Document Type: Article

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