The reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1, 1,1-trichloroethane, inhibits testosterone formation by cultured Leydig cells from neonatal rats

Reproductive Toxicology

Volumn 20, Issue 4, 2005, Pages 503-513

  Murono, Eisuke P ^a   Derk, Raymond C ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

HPTE; Neonatal Leydig cell; Testosterone

Indexed keywords

ANDROGEN RECEPTOR; CHLORPHENOTANE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; ESTROGEN RECEPTOR; METHOXYCHLOR; PREGNENOLONE; TESTOSTERONE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FETUS; LEYDIG CELL; MALE; NEWBORN; NONHUMAN; RAT; TESTOSTERONE SYNTHESIS;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHORIONIC GONADOTROPIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; INSECTICIDES; LEYDIG CELLS; MALE; METHOXYCHLOR; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE; TIME FACTORS;

EID: 25844525451     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2005.03.002     Document Type: Article

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