Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging

Molecular Endocrinology

Volumn 25, Issue 12, 2011, Pages 2157-2168

  Gore, Andrea C ^a   Walker, Deena M ^a   Zama, Aparna M ^b   Armenti, Annmarie E ^b   Uzumcu, Mehmet ^b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOCRINE DISRUPTOR; ESTRADIOL BENZOATE; METASTIN; METHOXYCHLOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ESTRUS CYCLE; FEMALE; FEMALE GENITAL SYSTEM; GENE EXPRESSION; HYPOTHALAMUS; LIFESPAN; MEDIOBASAL HYPOTHALAMUS; NONHUMAN; NUCLEAR REPROGRAMMING; POSTNATAL DEVELOPMENT; PREMATURE AGING; PREMATURE REPRODUCTIVE AGING; PRENATAL EXPOSURE; PREOPTIC AREA; PRIORITY JOURNAL; PYROSEQUENCING; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCTIVE TOXICITY; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; BODY WEIGHT; CPG ISLANDS; DNA METHYLATION; ENDOCRINE DISRUPTORS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROUS CYCLE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; KISSPEPTINS; MATERNAL-FETAL EXCHANGE; MENOPAUSE, PREMATURE; METHOXYCHLOR; MOLECULAR SEQUENCE DATA; PREGNANCY; PREOPTIC AREA; PROGESTERONE; PROMOTER REGIONS, GENETIC; RATS; RATS, INBRED F344; REGULATORY SEQUENCES, NUCLEIC ACID; UP-REGULATION;

EID: 82055194388     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1210     Document Type: Article

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