Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations

Reproductive Toxicology

Volumn 36, Issue , 2013, Pages 104-116

  Tracey, Rebecca ^a   Manikkam, Mohan ^a   Guerrero Bosagna, Carlos ^a   Skinner, Michael K ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

DNA methylation; Environmental epigenetics; Hydrocarbons; Obesity; Ovary; Puberty; Systems biology; Transgenerational

Indexed keywords

FUEL; JET FUEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ECOLOGICAL GENETICS; ENVIRONMENTAL EXPOSURE; EPIGENETICS; EPIMUTATION; FEMALE; GENOTOXICITY; INHERITANCE; MALE; MUTATION; NONHUMAN; OBESITY; OVARY FOLLICLE; OVARY POLYCYSTIC DISEASE; RAT; REPRODUCTIVE TOXICITY;

ABNORMALITIES, DRUG-INDUCED; ABNORMALITIES, MULTIPLE; ANIMALS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENITALIA, MALE; HYDROCARBONS; INFERTILITY, FEMALE; INFERTILITY, MALE; MALE; MATERNAL EXPOSURE; MUTAGENS; MUTATION; OBESITY; OVARY; PATERNAL EXPOSURE; PREGNANCY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SPERMATOZOA;

RATTUS;

EID: 84875638440     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2012.11.011     Document Type: Article

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