Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis

Toxicology

Volumn 176, Issue 1-2, 2002, Pages 67-75

  Latchoumycandane, C ^a   Mathur, P P ^a  

^a PONDICHERRY UNIVERSITY   (India)

Author keywords

Antioxidant enzymes; Lipid peroxidation; Methoxychlor; Microsome rich fractions; Mitochondrial fractions; Rat; Testis

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; METHOXYCHLOR; SUPEROXIDE DISMUTASE;

ANESTHESIA; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CENTRIFUGATION; CONTROLLED STUDY; DOSE RESPONSE; EPIDIDYMIS; LIPID PEROXIDATION; MICROSOME; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTATE VENTRAL LOBE; RAT; REPRODUCTION; SEMINAL VESICLE; TESTIS;

ANIMALS; ANTIOXIDANTS; CATALASE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENITALIA, MALE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALE; METHOXYCHLOR; MICROSOMES; MITOCHONDRIA; ORGAN SIZE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TESTIS;

ANIMALIA;

EID: 0036644278     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00138-5     Document Type: Article

References (35)

1. Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species
2. Lactoperoxidase catalyzed lipid peroxidation of microsome-rich and artificial membranes
3. Characteristics of monooxygenase-mediated covalent binding of methoxychlor in human and rat liver microsomes
4. Studies on the in vivo and in vitro estrogenic activities of methoxychlor and its metabolites. Role of hepatic mono-oxygenase in methoxychlor activation
5. Covalent binding of [14C] methoxychlor metabolite(s) to rat liver microsome-rich components
6. Purification and characterization of the flavoenzyme glutathione reductase from rat liver
7. Evidence for decreasing quality of semen during past 50 years
8. Hydroperoxide metabolism in mammalian organs
9. The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function
10. Endocrine disruptors and male reproductive function-a short review
11. Effect of lindane on antioxidant enzymes in epididymis and epididymal sperm of adult rats
12. Catalase
13. Effect of methoxychlor on the antioxidant system of goat epididymal sperm in vitro
14. A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat
15. The estrogenic and antiandrogenic pesticide methoxychlor alters the reproductive tract and behavior without affecting pituitary size or LH and prolactin secretion in male rats
16. Reactive oxygen species and human spermatozoa: Physiology and pathophysiology
17. Reactive oxygen species influence the acrosome reaction but not acrosin activity in human spermatozoa
18. 2+ with endoplasmic reticulum of rat liver
19. Toxicology of the male excurrent ducts and accessory sex glands
20. Possible estrogenic and/or antiandrogenic effects of methoxychlor on prolactin release in male rats
21. The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the mitochondrial and microsomal fractions of rat testis
22. The effect of methoxychlor on the epididymal antioxidant system of adult rat
23. Induction of oxidative stress in the epididymal sperm of rat after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
24. Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells
25. Involvement of superoxide anion radical in autooxidation of pyrogallol and a convenient assay for superoxide dismutase
26. Involvement of lysosomal enzymes in flutamide-induced stimulation in rat testis
27. Infections in the male genital tract and reactive oxygen species
28. Studies on quantitative and qualitative characterization of erythrocyte glutathione peroxidase
29. Lipid peroxidation and antioxidant enzyme activities in the rat testis after cigarette smoke inhalation or administration of polychlorinated biphenyls or polychlorinated naphthalenes
30. 2 production by chemically elicited peritoneal macrophages-induction by multiple nonphagocytic stimuli
31. Glutathione peroxidase, superoxide dismutase and catalase inactivation by peroxides and oxygen derived free radicals
32. Declining sperm counts in men-is there an endocrine cause?
33. Human cytochrome P450 catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP 1A2 in O-demethylation
34. Effect of lindane on testicular antioxidant system and steroidogenic enzymes in adult rats
35. Ligand-based identification of environmental estrogens