Novel cinnamic acid derivatives as antioxidant and anticancer agents: Design, synthesis and modeling studies

Molecules

Volumn 19, Issue 7, 2014, Pages 9655-9674

  Pontiki, Eleni ^a   Hadjipavlou Litina, Dimitra ^a   Litinas, Konstantinos ^a   Geromichalos, George ^b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b THEAGENIO CANCER HOSPITAL   (Greece)

Author keywords

Antioxidant activity; Cancer; Cinnamic acids; Inflammation; Lipoxygenase; Molecular docking

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; CINNAMIC ACID; CINNAMIC ACID DERIVATIVE; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; SCAVENGER;

CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; HUMAN; IC50; METABOLISM; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL LINE, TUMOR; CELL SURVIVAL; CINNAMATES; DRUG DESIGN; FREE RADICAL SCAVENGERS; HUMANS; INHIBITORY CONCENTRATION 50; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PROTEIN CONFORMATION;

EID: 84904787124     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19079655     Document Type: Article

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