Synthesis of new spiroindolinones incorporating a benzothiazole moiety as antioxidant agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1068-1077

  Karali, Nilgün ^a   Güzel, Özlen ^a   Özsoy, Nurten ^a   Özbey, Süheyla ^b   Salman, Aydin ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

3 Spiroindolinone; Antioxidant activity; Benzothiazole; Cytotoxicity; Synthesis; X ray analyses

Indexed keywords

1' METHYL 5' TRIFLUOROMETHOXY 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' ONE; 1',5' DIMETHYL 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' ONE; 1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 AMINOTHIOPHENOL; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); 5' BROMO 1' METHYL 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' ONE; 5' CHLORO 1' METHYL 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' ONE; 5' CHLORO 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' (1'H)ONE; 5' METHYL 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' (1'H)ONE; 5' NITRO 3H SPIRO[1,3 BENZOTHIAZOLE 2,3' INDOL] 2' (1'H)ONE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BENZOTHIAZOLE DERIVATIVE; INDOLE DERIVATIVE; LIPOSOME; TROLOX C; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; FINITE ELEMENT ANALYSIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SCAVENGING SYSTEM; STRUCTURE ACTIVITY RELATION; X RAY ANALYSIS;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; BENZOTHIAZOLES; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; HUMANS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SPIRO COMPOUNDS;

EID: 75849130376     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.001     Document Type: Article

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