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Volumn 37, Issue 4, 2014, Pages 1050-1058

Bufalin, a bioactive component of the Chinese medicine Chansu, inhibits inflammation and invasion of human rheumatoid arthritis fibroblast-like synoviocytes

Author keywords

bufalin; invasion; nuclear factor kappa B (NF B); rheumatoid arthritis fibroblast like synoviocyte; tumor necrosis factor alpha (TNF )

Indexed keywords

BUFALIN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STROMELYSIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; BUFADIENOLIDE DERIVATIVE; CHAN SU; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN;

EID: 84904751597     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9828-y     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 33745612984 scopus 로고    scopus 로고
    • Synovial fibroblasts: Key players in rheumatoid arthritis
    • DOI 10.1093/rheumatology/kel065
    • Huber, L.C., O. Distler, I. Tarner, R.E. Gay, S. Gay, and T. Pap. 2006. Synovial fibroblasts: key players in rheumatoid arthritis. Rheumatology 45: 669-675. (Pubitemid 43985334)
    • (2006) Rheumatology , vol.45 , Issue.6 , pp. 669-675
    • Huber, L.C.1    Distler, O.2    Tarner, I.3    Gay, R.E.4    Gay, S.5    Pap, T.6
  • 2
    • 0024353803 scopus 로고
    • Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritic rats. Studies on secretion by synovial fibroblast-like cells and immunohistologic localization
    • Lafyatis, R., N.L. Thompson, E.F. Remmers, K.C. Flanders, N.S. Roche, S.J. Kim, J.P. Case, M.B. Sporn, A.B. Roberts, and R.L. Wilder. 1989. Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritic rats. Studies on secretion by synovial fibroblast-like cells and immunohistologic localization. Journal of Immunology 143: 1142-1148. (Pubitemid 19211338)
    • (1989) Journal of Immunology , vol.143 , Issue.4 , pp. 1142-1148
    • Lafyatis, R.1    Thompson, N.L.2    Remmers, E.F.3    Flanders, K.C.4    Roche, N.S.5    Kim, S.-J.6    Case, J.P.7    Sporn, M.B.8    Roberts, A.B.9    Wilder, R.L.10
  • 3
    • 0026091413 scopus 로고
    • Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
    • Chu, C.Q., M. Field, M. Feldmann, and R.N. Maini. 1991. Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis and Rheumatism 34: 1125-1132.
    • (1991) Arthritis and Rheumatism , vol.34 , pp. 1125-1132
    • Chu, C.Q.1    Field, M.2    Feldmann, M.3    Maini, R.N.4
  • 4
    • 0026802287 scopus 로고
    • Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair
    • Chu, C.Q., M. Field, S. Allard, E. Abney, M. Feldmann, and R.N. Maini. 1992. Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair. British Journal of Rheumatology 31: 653-661.
    • (1992) British Journal of Rheumatology , vol.31 , pp. 653-661
    • Chu, C.Q.1    Field, M.2    Allard, S.3    Abney, E.4    Feldmann, M.5    Maini, R.N.6
  • 5
    • 0035555275 scopus 로고    scopus 로고
    • Pathogenesis of arthritis: Recent research progression
    • Feldmann, M. 2001. Pathogenesis of arthritis: recent research progression. Nature Immunology 2: 771-773.
    • (2001) Nature Immunology , vol.2 , pp. 771-773
    • Feldmann, M.1
  • 6
    • 0032428729 scopus 로고    scopus 로고
    • AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis
    • Han, Z.N., D.L. Boyle, A.M. Manning, and G.S. Firestein. 1998. AP-1 and NF-κB regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity 28: 197-208. (Pubitemid 29027651)
    • (1998) Autoimmunity , vol.28 , Issue.4 , pp. 197-208
    • Han, Z.1    Boyle, D.L.2    Manning, A.M.3    Firestein, G.S.4
  • 7
    • 0029563524 scopus 로고
    • Nuclear factor-kappaB in rheumatoid synovium: Localization of p50 and p65
    • DOI 10.1002/art.1780381209
    • Handel, M.L., L.B. McMorrow, and E.M. Gravallese. 1995. Nuclear factor-κB in rheumatoid synovium: localization of p50 and p65. Arthritis and Rheumatism 38: 1762-1770. (Pubitemid 26010277)
    • (1995) Arthritis and Rheumatism , vol.38 , Issue.12 , pp. 1762-1770
    • Handel, M.L.1    McMorrow, L.B.2    Gravallese, E.M.3
  • 8
    • 18644375615 scopus 로고    scopus 로고
    • Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes
    • Granet, C., W. Maslinski, and P. Miossec. 2004. Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes. Arthritis Research and Therapy 6: R190-R198.
    • (2004) Arthritis Research and Therapy , vol.6
    • Granet, C.1    Maslinski, W.2    Miossec, P.3
  • 9
    • 0031886794 scopus 로고    scopus 로고
    • Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: Spontaneous activation of NF-kappaB and CBF1
    • Miyazawa, K., A. Mori, K. Yamamoto, and H. Okudaira. 1998. Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-κB and CBF1. American Journal of Pathology 152: 793-803. (Pubitemid 28110726)
    • (1998) American Journal of Pathology , vol.152 , Issue.3 , pp. 793-803
    • Miyazawa, K.1    Mori, A.2    Yamamoto, K.3    Okudaira, H.4
  • 10
    • 0033178749 scopus 로고    scopus 로고
    • Essential role of T cell NF-kappaB activation in collagen-induced arthritis
    • Seetharaman, R., A.L. Mora, G. Nabozny, M. Boothby, and J. Chen. 1999. Essential role of T cell NF-kappaB activation in collagen-induced arthritis. Journal of Immunology 163: 1577-1583. (Pubitemid 29352782)
    • (1999) Journal of Immunology , vol.163 , Issue.3 , pp. 1577-1583
    • Seetharaman, R.1    Mora, A.L.2    Nabozny, G.3    Boothby, M.4    Chen, J.5
  • 14
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis
    • Bartok, B., and G.S. Firestein. 2010. Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunology Reviews 233: 233-255.
    • (2010) Immunology Reviews , vol.233 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 16
    • 35648988128 scopus 로고    scopus 로고
    • New therapies for treatment of rheumatoid arthritis
    • DOI 10.1016/S0140-6736(07)60784-3, PII S0140673607607843
    • Smolen, J.S., D. Aletaha, M. Koeller, M.H. Weisman, and P. Emery. 2007. New therapies for treatment of rheumatoid arthritis. Lancet 370: 1861-1874. (Pubitemid 350180008)
    • (2007) Lancet , vol.370 , Issue.9602 , pp. 1861-1874
    • Smolen, J.S.1    Aletaha, D.2    Koeller, M.3    Weisman, M.H.4    Emery, P.5
  • 17
    • 0038131975 scopus 로고    scopus 로고
    • Therapeutic strategies for rheumatoid arthritis
    • DOI 10.1038/nrd1109
    • Smolen, J.S., and G. Steiner. 2003. Therapeutic strategies for rheumatoid arthritis. Nature Reviews Drug Discovery 2: 473-488. (Pubitemid 37361728)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.6 , pp. 473-488
    • Smolen, J.S.1    Steiner, G.2
  • 18
    • 84870381900 scopus 로고    scopus 로고
    • Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: Preparation, cellular uptake, tissue distribution, and anticancer activity
    • Yin, P., Y. Wang, Y. Qiu, L. Hou, X. Liu, J. Qin, Y. Duan, P. Liu, M. Qiu, and Q. Li. 2012. Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity. International Journal of Nanomedicine 7: 3961-3969.
    • (2012) International Journal of Nanomedicine , vol.7 , pp. 3961-3969
    • Yin, P.1    Wang, Y.2    Qiu, Y.3    Hou, L.4    Liu, X.5    Qin, J.6    Duan, Y.7    Liu, P.8    Qiu, M.9    Li, Q.10
  • 19
    • 84873642692 scopus 로고    scopus 로고
    • Bufalin prevents the migration and invasion of T24 bladder carcinoma cells through the inactivation of matrix metalloproteinases and modulation of tight junctions
    • Hong, S.H., G.Y. Kim, Y.C. Chang, S.K. Moon, W.J. Kim, and Y.H. Choi. 2013. Bufalin prevents the migration and invasion of T24 bladder carcinoma cells through the inactivation of matrix metalloproteinases and modulation of tight junctions. International Journal of Oncology 42: 277-286.
    • (2013) International Journal of Oncology , vol.42 , pp. 277-286
    • Hong, S.H.1    Kim, G.Y.2    Chang, Y.C.3    Moon, S.K.4    Kim, W.J.5    Choi, Y.H.6
  • 20
    • 84890565131 scopus 로고    scopus 로고
    • Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways
    • Chueh, F.S., Y.Y. Chen, A.C. Huang, H.C. Ho, C.L. Liao, J.S. Yang, C.L. Kuo, and J.G. Chung. 2014. Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways. Environmental Toxicology 29: 21-29.
    • (2014) Environmental Toxicology , vol.29 , pp. 21-29
    • Chueh, F.S.1    Chen, Y.Y.2    Huang, A.C.3    Ho, H.C.4    Liao, C.L.5    Yang, J.S.6    Kuo, C.L.7    Chung, J.G.8
  • 21
    • 84919847871 scopus 로고    scopus 로고
    • Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/- 9-signaling pathways
    • doi:10.1002/tox.21896
    • Chen, Y.Y., H.F. Lu, S.C. Hsu, C.L. Kuo, S.J. Chang, J.J. Lin, P.P.Wu, J.Y. Liu, C.H. Lee, J.G. Chung, and J.B. Chang. 2013. Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways. Environmental Toxicology. doi:10.1002/tox.21896.
    • (2013) Environmental Toxicology
    • Chen, Y.Y.1    Lu, H.F.2    Hsu, S.C.3    Kuo, C.L.4    Chang, S.J.5    Lin, J.J.6    Wu, P.P.7    Liu, J.Y.8    Lee, C.H.9    Chung, J.G.10    Chang, J.B.11
  • 22
    • 84880334418 scopus 로고    scopus 로고
    • Bufalin, a component in Chansu, inhibits proliferation and invasion of hepatocellular carcinoma cells
    • Qiu, D.Z., Z.J. Zhang, W.Z. Wu, and Y.K. Yang. 2013. Bufalin, a component in Chansu, inhibits proliferation and invasion of hepatocellular carcinoma cells. BMC Complementary and Alternative Medicine 13: 185.
    • (2013) BMC Complementary and Alternative Medicine , vol.13 , pp. 185
    • Qiu, D.Z.1    Zhang, Z.J.2    Wu, W.Z.3    Yang, Y.K.4
  • 24
    • 84879801389 scopus 로고    scopus 로고
    • Celastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-κB- mediated matrix metalloproteinase-9 expression
    • Li, G., D. Liu, Y. Zhang, Y. Qian, H. Zhang, S. Guo, M. Sunagawa, T. Hisamitsu, and Y. Liu. 2013. Celastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-κB-mediated matrix metalloproteinase-9 expression. PLoS One 8: e68905.
    • (2013) PLoS One , vol.8
    • Li, G.1    Liu, D.2    Zhang, Y.3    Qian, Y.4    Zhang, H.5    Guo, S.6    Sunagawa, M.7    Hisamitsu, T.8    Liu, Y.9
  • 25
    • 82455162312 scopus 로고    scopus 로고
    • Negative regulation of NF-κB and its involvement in rheumatoid arthritis
    • van Loo, G., and R. Beyaert. 2011. Negative regulation of NF-κB and its involvement in rheumatoid arthritis. Arthritis Research and Therapy 13: 221.
    • (2011) Arthritis Research and Therapy , vol.13 , pp. 221
    • Van Loo, G.1    Beyaert, R.2
  • 26
    • 0034942860 scopus 로고    scopus 로고
    • NF-kappaB in rheumatoid arthritis: A pivotal regulator of inflammation, hyperplasia, and tissue destruction
    • DOI 10.1186/ar300
    • Makarov, S.S. 2001. NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Research 3: 200-206. (Pubitemid 32621955)
    • (2001) Arthritis Research , vol.3 , Issue.4 , pp. 200-206
    • Makarov, S.S.1
  • 27
    • 80052026371 scopus 로고    scopus 로고
    • Anti-inflammatory activities of Chinese herbal medicine sinomenine and Liang Miao San on tumor necrosis factor-α-activated human fibroblast-like synoviocytes in rheumatoid arthritis
    • Chen, D.P., C.K. Wong, P.C. Leung, K.P. Fung, C.B. Lau, C.P. Lau, E.K. Li, L.S. Tam, and C.W. Lam. 2011. Anti-inflammatory activities of Chinese herbal medicine sinomenine and Liang Miao San on tumor necrosis factor-α- activated human fibroblast-like synoviocytes in rheumatoid arthritis. Journal of Ethnopharmacology 137: 457-468.
    • (2011) Journal of Ethnopharmacology , vol.137 , pp. 457-468
    • Chen, D.P.1    Wong, C.K.2    Leung, P.C.3    Fung, K.P.4    Lau, C.B.5    Lau, C.P.6    Li, E.K.7    Tam, L.S.8    Lam, C.W.9
  • 29
    • 34447324890 scopus 로고    scopus 로고
    • Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes
    • DOI 10.1093/rheumatology/kem014
    • Xu, H., Y. He, X. Yang, L. Liang, Z. Zhan, Y. Ye, X. Yang, F. Lian, and L. Sun. 2007. Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. Rheumatology (Oxford) 46: 920-926. (Pubitemid 47062496)
    • (2007) Rheumatology , vol.46 , Issue.6 , pp. 920-926
    • Xu, H.1    He, Y.2    Yang, X.3    Liang, L.4    Zhan, Z.5    Ye, Y.6    Yang, X.7    Lian, F.8    Sun, L.9


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