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Volumn 13, Issue , 2013, Pages

Bufalin, a component in Chansu, inhibits proliferation and invasion of hepatocellular carcinoma cells

Author keywords

AKT signaling pathway; Bufalin; Hepatocellular carcinoma; Invasion; Proliferation

Indexed keywords

BETA CATENIN; BUFALIN; GELATINASE A; GELATINASE B; PROTEIN KINASE B; UVOMORULIN;

EID: 84880334418     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-13-185     Document Type: Article
Times cited : (73)

References (27)
  • 4
    • 3042742830 scopus 로고    scopus 로고
    • In vitro chemosensitivity of hepatocellular carcinoma for hepatic arterial infusion chemotherapy using the MTT assay with the combinations of antitumor drugs
    • Furukawa S. In vitro chemosensitivity of hepatocellular carcinoma for hepatic arterial infusion chemotherapy using the MTT assay with the combinations of antitumor drugs. Kurume Med J 2004, 51:25-33.
    • (2004) Kurume Med J , vol.51 , pp. 25-33
    • Furukawa, S.1
  • 5
    • 77952369613 scopus 로고    scopus 로고
    • Residual hepatocellular carcinoma after oxaliplatin treatment has increased metastatic potential in a nude mouse model and is attenuated by Songyou Yin
    • Xiong W, Ren ZG, Qiu SJ, Sun HC, Wang L, Liu BB, Li QS, Zhang W, Zhu XD, Liu L, et al. Residual hepatocellular carcinoma after oxaliplatin treatment has increased metastatic potential in a nude mouse model and is attenuated by Songyou Yin. BMC Cancer 2010, 10:1471-2407.
    • (2010) BMC Cancer , vol.10 , pp. 1471-2407
    • Xiong, W.1    Ren, Z.G.2    Qiu, S.J.3    Sun, H.C.4    Wang, L.5    Liu, B.B.6    Li, Q.S.7    Zhang, W.8    Zhu, X.D.9    Liu, L.10
  • 6
    • 0032076578 scopus 로고    scopus 로고
    • Bufadienolides from animal and plant sources
    • Krenn L, Kopp B. Bufadienolides from animal and plant sources. Phytochemistry 1998, 48:1-29.
    • (1998) Phytochemistry , vol.48 , pp. 1-29
    • Krenn, L.1    Kopp, B.2
  • 7
    • 70449376872 scopus 로고    scopus 로고
    • Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer
    • Meng Z, Yang P, Shen Y, Bei W, Zhang Y, Ge Y, Newman RA, Cohen L, Liu L, Thornton B, et al. Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer. Cancer 2009, 115:5309-5318.
    • (2009) Cancer , vol.115 , pp. 5309-5318
    • Meng, Z.1    Yang, P.2    Shen, Y.3    Bei, W.4    Zhang, Y.5    Ge, Y.6    Newman, R.A.7    Cohen, L.8    Liu, L.9    Thornton, B.10
  • 8
    • 58149229785 scopus 로고    scopus 로고
    • Efficacy and safety of gemcitabine-oxaliplatin combined with huachansu in patients with advanced gallbladder carcinoma
    • Qin TJ, Zhao XH, Yun J, Zhang LX, Ruan ZP, Pan BR. Efficacy and safety of gemcitabine-oxaliplatin combined with huachansu in patients with advanced gallbladder carcinoma. World J Gastroenterol 2008, 14:5210-5216.
    • (2008) World J Gastroenterol , vol.14 , pp. 5210-5216
    • Qin, T.J.1    Zhao, X.H.2    Yun, J.3    Zhang, L.X.4    Ruan, Z.P.5    Pan, B.R.6
  • 9
    • 79952101058 scopus 로고    scopus 로고
    • Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor
    • Qi F, Li A, Inagaki Y, Kokudo N, Tamura S, Nakata M, Tang W. Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor. Int Immunopharmacol 2011, 11:342-349.
    • (2011) Int Immunopharmacol , vol.11 , pp. 342-349
    • Qi, F.1    Li, A.2    Inagaki, Y.3    Kokudo, N.4    Tamura, S.5    Nakata, M.6    Tang, W.7
  • 11
    • 53649103519 scopus 로고    scopus 로고
    • Metastasis and AKT activation
    • Qiao M, Sheng S, Pardee AB. Metastasis and AKT activation. Cell Cycle 2008, 7:2991-2996.
    • (2008) Cell Cycle , vol.7 , pp. 2991-2996
    • Qiao, M.1    Sheng, S.2    Pardee, A.B.3
  • 13
    • 84855989334 scopus 로고    scopus 로고
    • HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway
    • Jung KH, Choi MJ, Hong S, Lee H, Hong SW, Zheng HM, Lee HS, Hong S, Hong SS. HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway. Cancer Lett 2012, 316:187-195.
    • (2012) Cancer Lett , vol.316 , pp. 187-195
    • Jung, K.H.1    Choi, M.J.2    Hong, S.3    Lee, H.4    Hong, S.W.5    Zheng, H.M.6    Lee, H.S.7    Hong, S.8    Hong, S.S.9
  • 14
    • 84855661853 scopus 로고    scopus 로고
    • Activation of PI3 kinase/Akt/HIF-1alpha pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma
    • Jiao M, Nan KJ. Activation of PI3 kinase/Akt/HIF-1alpha pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma. Int J Oncol 2012, 40:461-468.
    • (2012) Int J Oncol , vol.40 , pp. 461-468
    • Jiao, M.1    Nan, K.J.2
  • 15
    • 77950683362 scopus 로고    scopus 로고
    • Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling
    • Heuberger J, Birchmeier W. Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol 2010, 2:a2915.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Heuberger, J.1    Birchmeier, W.2
  • 16
    • 0031686745 scopus 로고    scopus 로고
    • Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression
    • Llorens A, Rodrigo I, Lopez-Barcons L, Gonzalez-Garrigues M, Lozano E, Vinyals A, Quintanilla M, Cano A, Fabra A. Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression. Lab Invest 1998, 78:1131-1142.
    • (1998) Lab Invest , vol.78 , pp. 1131-1142
    • Llorens, A.1    Rodrigo, I.2    Lopez-Barcons, L.3    Gonzalez-Garrigues, M.4    Lozano, E.5    Vinyals, A.6    Quintanilla, M.7    Cano, A.8    Fabra, A.9
  • 17
    • 0033178761 scopus 로고    scopus 로고
    • Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection
    • Luo J, Lubaroff DM, Hendrix MJ. Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection. Cancer Res 1999, 59:3552-3556.
    • (1999) Cancer Res , vol.59 , pp. 3552-3556
    • Luo, J.1    Lubaroff, D.M.2    Hendrix, M.J.3
  • 18
    • 47549098328 scopus 로고    scopus 로고
    • New insights of epithelial-mesenchymal transition in cancer metastasis
    • Wu Y, Zhou BP. New insights of epithelial-mesenchymal transition in cancer metastasis. Acta Biochim Biophys Sin (Shanghai) 2008, 40:643-650.
    • (2008) Acta Biochim Biophys Sin (Shanghai) , vol.40 , pp. 643-650
    • Wu, Y.1    Zhou, B.P.2
  • 20
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways
    • Larue L, Bellacosa A. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways. Oncogene 2005, 24:7443-7454.
    • (2005) Oncogene , vol.24 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2
  • 21
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 22
    • 75149180021 scopus 로고    scopus 로고
    • Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth
    • Baryawno N, Sveinbjörnsson B, Eksborg S, Chen CS, Kogner P, Johnsen JI. Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth. Cancer Res 2010, 70:266-276.
    • (2010) Cancer Res , vol.70 , pp. 266-276
    • Baryawno, N.1    Sveinbjörnsson, B.2    Eksborg, S.3    Chen, C.S.4    Kogner, P.5    Johnsen, J.I.6
  • 24
    • 0033383637 scopus 로고    scopus 로고
    • Digitoxin is a potential anticancer agent for several types of cancer
    • Haux J. Digitoxin is a potential anticancer agent for several types of cancer. Med Hypotheses 1999, 53:543-548.
    • (1999) Med Hypotheses , vol.53 , pp. 543-548
    • Haux, J.1
  • 25
    • 68249093818 scopus 로고    scopus 로고
    • Targeting the phosphoinositide 3-kinase pathway in cancer
    • Liu P, Cheng H, Roberts TM, Zhao JJ. Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov 2009, 8:627-644.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 627-644
    • Liu, P.1    Cheng, H.2    Roberts, T.M.3    Zhao, J.J.4
  • 26
    • 78651518059 scopus 로고    scopus 로고
    • Effects of bufalin on the proliferation of human lung cancer cells and its molecular mechanisms of action
    • Jiang Y, Zhang Y, Luan J, Duan H, Zhang F, Yagasaki K, Zhang G. Effects of bufalin on the proliferation of human lung cancer cells and its molecular mechanisms of action. Cytotechnology 2010, 62:573-583.
    • (2010) Cytotechnology , vol.62 , pp. 573-583
    • Jiang, Y.1    Zhang, Y.2    Luan, J.3    Duan, H.4    Zhang, F.5    Yagasaki, K.6    Zhang, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.