Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex

Nature Communications

Volumn 4, Issue , 2013, Pages

  Krauß, Sybille ^a   Griesche, Nadine ^a   Jastrzebska, Ewa ^b,c   Chen, Changwei ^d   Rutschow, Désiree ^d   Achmuller, Clemens ^e,f,j   Dorn, Stephanie ^a   Boesch, Sylvia M ^f   Lalowski, Maciej ^g,h   Wanker, Erich ^g   Schneider, Rainer ^c,e   Schweiger, Susann ^c,d,i  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

^e UNIVERSITY OF INNSBRUCK   (Austria)

^f INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^g MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^h UNIVERSITY OF HELSINKI   (Finland)

ⁱ JOHANNES GUTENBERG UNIVERSITY   (Germany)

^j NOVARTIS PHARMA AG   (Switzerland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MID1 PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; MAMMAL; PROTEIN; RNA;

ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; CAG REPEAT; CHEMICAL STRUCTURE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; HELA CELLS; HUMANS; LUCIFERASES; MICE; MICROTUBULE PROTEINS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; NUCLEOTIDE MOTIFS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN PHOSPHATASE 2; RNA, MESSENGER; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84874607780     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2514     Document Type: Article

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