-
1
-
-
0037062609
-
The prevalence of frontotemporal dementia
-
Ratnavalli E, Brayne C, Dawson K, Hodges JR,. The prevalence of frontotemporal dementia. Neurology 2002; 58: 1615-1621. (Pubitemid 34602891)
-
(2002)
Neurology
, vol.58
, Issue.11
, pp. 1615-1621
-
-
Ratnavalli, E.1
Brayne, C.2
Dawson, K.3
Hodges, J.R.4
-
2
-
-
24644437283
-
Frontotemporal dementia progresses to death faster than Alzheimer disease
-
DOI 10.1212/01.wnl.0000173837.82820.9f
-
Roberson ED, Hesse JH, Rose KD, et al. Frontotemporal dementia progresses to death faster than Alzheimer disease. Neurology 2005; 65: 719-725. (Pubitemid 41285851)
-
(2005)
Neurology
, vol.65
, Issue.5
, pp. 719-725
-
-
Roberson, E.D.1
Hesse, J.H.2
Rose, K.D.3
Slama, H.4
Johnson, J.K.5
Yaffe, K.6
Forman, M.S.7
Miller, C.A.8
Trojanowski, J.Q.9
Kramer, J.H.10
Miller, B.L.11
-
3
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
DOI 10.1038/nature01262
-
Mouse Genome Sequencing Consortium, Waterston RH, Lindblad-Toh K, et al. Initial sequencing and comparative analysis of the mouse genome. Nature 2002; 420: 520-562. (Pubitemid 35477048)
-
(2002)
Nature
, vol.420
, Issue.6915
, pp. 520-562
-
-
Waterston, R.H.1
Lindblad-Toh, K.2
Birney, E.3
Rogers, J.4
Abril, J.F.5
Agarwal, P.6
Agarwala, R.7
Ainscough, R.8
Alexandersson, M.9
An, P.10
Antonarakis, S.E.11
Attwood, J.12
Baertsch, R.13
Bailey, J.14
Barlow, K.15
Beck, S.16
Berry, E.17
Birren, B.18
Bloom, T.19
Bork, P.20
Botcherby, M.21
Bray, N.22
Brent, M.R.23
Brown, D.G.24
Brown, S.D.25
Bult, C.26
Burton, J.27
Butler, J.28
Campbell, R.D.29
Carninci, P.30
Cawley, S.31
Chiaromonte, F.32
Chinwalla, A.T.33
Church, D.M.34
Clamp, M.35
Clee, C.36
Collins, F.S.37
Cook, L.L.38
Copley, R.R.39
Coulson, A.40
Couronne, O.41
Cuff, J.42
Curwen, V.43
Cutts, T.44
Daly, M.45
David, R.46
Davies, J.47
Delehaunty, K.D.48
Deri, J.49
Dermitzakis, E.T.50
Dewey, C.51
Dickens, N.J.52
Diekhans, M.53
Dodge, S.54
Dubchak, I.55
Dunn, D.M.56
Eddy, S.R.57
Elnitski, L.58
Emes, R.D.59
Eswara, P.60
Eyras, E.61
Felsenfeld, A.62
Fewell, G.A.63
Flicek, P.64
Foley, K.65
Frankel, W.N.66
Fulton, L.A.67
Fulton, R.S.68
Furey, T.S.69
Gage, D.70
Gibbs, R.A.71
Glusman, G.72
Gnerre, S.73
Goldman, N.74
Goodstadt, L.75
Grafham, D.76
Graves, T.A.77
Green, E.D.78
Gregory, S.79
Guigo, R.80
Guyer, M.81
Hardison, R.C.82
Haussler, D.83
Hayashizaki, Y.84
Hillier, L.W.85
Hinrichs, A.86
Hlavina, W.87
Holzer, T.88
Hsu, F.89
Hua, A.90
Hubbard, T.91
Hunt, A.92
Jackson, I.93
Jaffe, D.B.94
Steven Johnson, L.95
Jones, M.96
Jones, T.A.97
Joy, A.98
Kamal, M.99
more..
-
4
-
-
34247554428
-
Conservation of regional gene expression in mouse and human brain
-
Strand AD, Aragaki AK, Baquet ZC, et al. Conservation of regional gene expression in mouse and human brain. PLoS Genet 2007; 3: e59.
-
(2007)
PLoS Genet
, vol.3
-
-
Strand, A.D.1
Aragaki, A.K.2
Baquet, Z.C.3
-
5
-
-
64149093013
-
Neurodegenerative diseases target large-scale human brain networks
-
Seeley WW, Crawford RK, Zhou J, et al. Neurodegenerative diseases target large-scale human brain networks. Neuron 2009; 62: 42-52.
-
(2009)
Neuron
, vol.62
, pp. 42-52
-
-
Seeley, W.W.1
Crawford, R.K.2
Zhou, J.3
-
6
-
-
20844443269
-
Frontotemporal lobar degeneration: Demographic characteristics of 353 patients
-
DOI 10.1001/archneur.62.6.925
-
Johnson JK, Diehl J, Mendez MF, et al. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol 2005; 62: 925-930. (Pubitemid 40973454)
-
(2005)
Archives of Neurology
, vol.62
, Issue.6
, pp. 925-930
-
-
Johnson, J.K.1
Diehl, J.2
Mendez, M.F.3
Neuhaus, J.4
Shapira, J.S.5
Forman, M.6
Chute, D.J.7
Roberson, E.D.8
Pace-Savitsky, C.9
Neumann, M.10
Chow, T.W.11
Rosen, H.J.12
Forstl, H.13
Kurz, A.14
Miller, B.L.15
-
7
-
-
77649187519
-
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: An update
-
Mackenzie IR, Neumann M, Bigio EH, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol 2010; 119: 1-4.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 1-4
-
-
MacKenzie, I.R.1
Neumann, M.2
Bigio, E.H.3
-
8
-
-
79959599081
-
A harmonized classification system for FTLD-TDP pathology
-
Mackenzie IR, Neumann M, Baborie A, et al. A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol 2011; 122: 111-113.
-
(2011)
Acta Neuropathol
, vol.122
, pp. 111-113
-
-
MacKenzie, I.R.1
Neumann, M.2
Baborie, A.3
-
9
-
-
84863393788
-
Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72
-
Boeve BF, Boylan KB, Graff-Radford NR, et al. Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72. Brain 2012; 135: 765-783.
-
(2012)
Brain
, vol.135
, pp. 765-783
-
-
Boeve, B.F.1
Boylan, K.B.2
Graff-Radford, N.R.3
-
10
-
-
34547663747
-
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
-
DOI 10.2353/ajpath.2007.070182
-
Cairns NJ, Neumann M, Bigio EH, et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol 2007; 171: 227-240. (Pubitemid 47342406)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.1
, pp. 227-240
-
-
Cairns, N.J.1
Neumann, M.2
Bigio, E.H.3
Holm, I.E.4
Troost, D.5
Hatanpaa, K.J.6
Foong, C.7
White III, C.L.8
Schneider, J.A.9
Kretzschmar, H.A.10
Carter, D.11
Taylor-Reinwald, L.12
Paulsmeyer, K.13
Strider, J.14
Gitcho, M.15
Goate, A.M.16
Morris, J.C.17
Mishra, M.18
Kwong, L.K.19
Stieber, A.20
Xu, Y.21
Forman, M.S.22
Trojanowski, J.Q.23
Lee, V.M.-Y.24
Mackenzie, I.R.A.25
more..
-
11
-
-
80052636880
-
Mutational analysis of TARDBP in neurodegenerative diseases
-
Ticozzi N, Leclerc AL, van Blitterswijk M, et al. Mutational analysis of TARDBP in neurodegenerative diseases. Neurobiol Aging 2011; 32: 2096-2099.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 2096-2099
-
-
Ticozzi, N.1
Leclerc, A.L.2
Van Blitterswijk, M.3
-
12
-
-
65649112431
-
TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration
-
Benajiba L, Le Ber I, Camuzat A, et al. TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration. Ann Neurol 2009; 65: 470-473.
-
(2009)
Ann Neurol
, vol.65
, pp. 470-473
-
-
Benajiba, L.1
Le Ber, I.2
Camuzat, A.3
-
13
-
-
70449528427
-
TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy
-
Gitcho MA, Bigio EH, Mishra M, et al. TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy. Acta Neuropathol 2009; 118: 633-645.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 633-645
-
-
Gitcho, M.A.1
Bigio, E.H.2
Mishra, M.3
-
14
-
-
70350572209
-
TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea
-
Kovacs GG, Murrell JR, Horvath S, et al. TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea. Mov Disord 2009; 24: 1843-1847.
-
(2009)
Mov Disord
, vol.24
, pp. 1843-1847
-
-
Kovacs, G.G.1
Murrell, J.R.2
Horvath, S.3
-
15
-
-
78349241067
-
Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: Disease-associated pathways
-
Barmada SJ, Finkbeiner S,. Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways. Rev Neurosci 2010; 21: 251-272.
-
(2010)
Rev Neurosci
, vol.21
, pp. 251-272
-
-
Barmada, S.J.1
Finkbeiner, S.2
-
16
-
-
0029066110
-
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
-
Ou SH, Wu F, Harrich D, et al. Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J Virol 1995; 69: 3584-3596.
-
(1995)
J Virol
, vol.69
, pp. 3584-3596
-
-
Ou, S.H.1
Wu, F.2
Harrich, D.3
-
17
-
-
74749107048
-
TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis
-
Wu LS, Cheng WC, Hou SC, et al. TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis. Genesis 2010; 48: 56-62.
-
(2010)
Genesis
, vol.48
, pp. 56-62
-
-
Wu, L.S.1
Cheng, W.C.2
Hou, S.C.3
-
18
-
-
77949878273
-
TDP-43 is a developmentally regulated protein essential for early embryonic development
-
Sephton CF, Good SK, Atkin S, et al. TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem 2010; 285: 6826-6834.
-
(2010)
J Biol Chem
, vol.285
, pp. 6826-6834
-
-
Sephton, C.F.1
Good, S.K.2
Atkin, S.3
-
19
-
-
77953026500
-
Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis
-
Kraemer BC, Schuck T, Wheeler JM, et al. Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis. Acta Neuropathol 2010; 119: 409-419.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 409-419
-
-
Kraemer, B.C.1
Schuck, T.2
Wheeler, J.M.3
-
20
-
-
77958012134
-
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
-
Chiang P-M, Ling J, Jeong YH, et al. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci U S A 2010; 107: 16320-16324.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16320-16324
-
-
Chiang, P.-M.1
Ling, J.2
Jeong, Y.H.3
-
21
-
-
84865028374
-
Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice
-
Wu L-S, Cheng W-C, Shen C-K,. Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice. J Biol Chem 2012; 287: 27335-27344.
-
(2012)
J Biol Chem
, vol.287
, pp. 27335-27344
-
-
Wu, L.-S.1
Cheng, W.-C.2
Shen, C.-K.3
-
22
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska I, Bell S, Cairns NJ, et al. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A 2009; 106: 18809-18814.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
-
23
-
-
77649269011
-
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
-
Wils H, Kleinberger G, Janssens J, et al. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A 2010; 107: 3858-3863.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3858-3863
-
-
Wils, H.1
Kleinberger, G.2
Janssens, J.3
-
24
-
-
77956199371
-
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice
-
Xu YF, Gendron TF, Zhang YJ, et al. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci 2010; 30: 10851-10859.
-
(2010)
J Neurosci
, vol.30
, pp. 10851-10859
-
-
Xu, Y.F.1
Gendron, T.F.2
Zhang, Y.J.3
-
25
-
-
79251518539
-
Progressive motor weakness in transgenic mice expressing human TDP-43
-
Stallings NR, Puttaparthi K, Luther CM, et al. Progressive motor weakness in transgenic mice expressing human TDP-43. Neurobiol Dis 2010; 40: 404-414.
-
(2010)
Neurobiol Dis
, vol.40
, pp. 404-414
-
-
Stallings, N.R.1
Puttaparthi, K.2
Luther, C.M.3
-
26
-
-
77958022745
-
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
-
Shan X, Chiang PM, Price DL, Wong PC,. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc Natl Acad Sci U S A 2010; 107: 16325-16330.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16325-16330
-
-
Shan, X.1
Chiang, P.M.2
Price, D.L.3
Wong, P.C.4
-
27
-
-
0036940998
-
Constant involvement of the Betz cells and pyramidal tract in amyotrophic lateral sclerosis with dementia: A clinicopathological study of eight autopsy cases
-
Tsuchiya K, Ikeda K, Mimura M, et al. Constant involvement of the Betz cells and pyramidal tract in amyotrophic lateral sclerosis with dementia: a clinicopathological study of eight autopsy cases. Acta Neuropathol 2002; 104: 249-259. (Pubitemid 36075385)
-
(2002)
Acta Neuropathologica
, vol.104
, Issue.3
, pp. 249-259
-
-
Tsuchiya, K.1
Ikeda, K.2
Mimura, M.3
Takahashi, M.4
Miyazaki, H.5
Anno, M.6
Shiotsu, H.7
Akabane, H.8
Niizato, K.9
Uchihara, T.10
Tominaga, I.11
Nakano, I.12
-
28
-
-
33846019601
-
Early frontotemporal dementia targets neurons unique to apes and humans
-
DOI 10.1002/ana.21055
-
Seeley WW, Carlin DA, Allman JM, et al. Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol 2006; 60: 660-667. (Pubitemid 46048483)
-
(2006)
Annals of Neurology
, vol.60
, Issue.6
, pp. 660-667
-
-
Seeley, W.W.1
Carlin, D.A.2
Allman, J.M.3
Macedo, M.N.4
Bush, C.5
Miller, B.L.6
DeArmond, S.J.7
-
29
-
-
77955395385
-
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
-
Tsai K-J, Yang C-H, Fang Y-H, et al. Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U. J Exp Med 2010; 207: 1661-1673.
-
(2010)
J Exp Med
, vol.207
, pp. 1661-1673
-
-
Tsai, K.-J.1
Yang, C.-H.2
Fang, Y.-H.3
-
30
-
-
79551523377
-
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
-
Igaz LM, Kwong LK, Lee EB, et al. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. J Clin Invest 2011; 121: 726-738.
-
(2011)
J Clin Invest
, vol.121
, pp. 726-738
-
-
Igaz, L.M.1
Kwong, L.K.2
Lee, E.B.3
-
31
-
-
80052936462
-
Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
-
Swarup V, Phaneuf D, Bareil C, et al. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain 2011; 134 (pt 9): 2610-2626.
-
(2011)
Brain
, vol.134
, Issue.PART 9
, pp. 2610-2626
-
-
Swarup, V.1
Phaneuf, D.2
Bareil, C.3
-
32
-
-
33749568019
-
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration
-
DOI 10.1093/hmg/ddl241
-
Gass J, Cannon A, Mackenzie IR, et al. Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Hum Mol Genet 2006; 15: 2988-3001. (Pubitemid 44530703)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.20
, pp. 2988-3001
-
-
Gass, J.1
Cannon, A.2
Mackenzie, I.R.3
Boeve, B.4
Baker, M.5
Adamson, J.6
Crook, R.7
Melquist, S.8
Kuntz, K.9
Petersen, R.10
Josephs, K.11
Pickering-Brown, S.M.12
Graff-Radford, N.13
Uitti, R.14
Dickson, D.15
Wszolek, Z.16
Gonzalez, J.17
Beach, T.G.18
Bigio, E.19
Johnson, N.20
Weintraub, S.21
Mesulam, M.22
White III, C.L.23
Woodruff, B.24
Caselli, R.25
Hsiung, G.-Y.26
Feldman, H.27
Knopman, D.28
Hutton, M.29
Rademakers, R.30
more..
-
33
-
-
79953879390
-
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration
-
Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Arch Neurol 2011; 68: 488-497.
-
(2011)
Arch Neurol
, vol.68
, pp. 488-497
-
-
Chen-Plotkin, A.S.1
Martinez-Lage, M.2
Sleiman, P.M.3
-
35
-
-
33746919083
-
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
-
DOI 10.1038/nature05016, PII NATURE05016
-
Baker M, Mackenzie IR, Pickering-Brown SM, et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 2006; 442: 916-919. (Pubitemid 44285946)
-
(2006)
Nature
, vol.442
, Issue.7105
, pp. 916-919
-
-
Baker, M.1
Mackenzie, I.R.2
Pickering-Brown, S.M.3
Gass, J.4
Rademakers, R.5
Lindholm, C.6
Snowden, J.7
Adamson, J.8
Sadovnick, A.D.9
Rollinson, S.10
Cannon, A.11
Dwosh, E.12
Neary, D.13
Melquist, S.14
Richardson, A.15
Dickson, D.16
Berger, Z.17
Eriksen, J.18
Robinson, T.19
Zehr, C.20
Dickey, C.A.21
Crook, R.22
McGowan, E.23
Mann, D.24
Boeve, B.25
Feldman, H.26
Hutton, M.27
more..
-
36
-
-
33746910649
-
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
-
DOI 10.1038/nature05017, PII NATURE05017
-
Cruts M, Gijselinck I, van der Zee J, et al. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 2006; 442: 920-924. (Pubitemid 44285947)
-
(2006)
Nature
, vol.442
, Issue.7105
, pp. 920-924
-
-
Cruts, M.1
Gijselinck, I.2
Van Der Zee, J.3
Engelborghs, S.4
Wils, H.5
Pirici, D.6
Rademakers, R.7
Vandenberghe, R.8
Dermaut, B.9
Martin, J.-J.10
Van Duijn, C.11
Peeters, K.12
Sciot, R.13
Santens, P.14
De Pooter, T.15
Mattheijssens, M.16
Van Den Broeck, M.17
Cuijt, I.18
Vennekens, K.19
De Deyn, P.P.20
Kumar-Singh, S.21
Van Broeckhoven, C.22
more..
-
37
-
-
38149123302
-
Progranulin locus deletion in frontotemporal dementia
-
Gijselinck I, van der Zee J, Engelborghs S, et al. Progranulin locus deletion in frontotemporal dementia. Hum Mutat 2008; 29: 53-58.
-
(2008)
Hum Mutat
, vol.29
, pp. 53-58
-
-
Gijselinck, I.1
Van Der Zee, J.2
Engelborghs, S.3
-
38
-
-
42049108445
-
Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia
-
DOI 10.1002/humu.20681
-
Mukherjee O, Wang J, Gitcho M, et al. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia. Hum Mutat 2008; 29: 512-521. (Pubitemid 351536990)
-
(2008)
Human Mutation
, vol.29
, Issue.4
, pp. 512-521
-
-
Mukherjee, O.1
Wang, J.2
Gitcho, M.3
Chakraverty, S.4
Taylor-Reinwald, L.5
Shears, S.6
Kauwe, J.S.K.7
Norton, J.8
Levitch, D.9
Bigio, E.H.10
Hatanpaa, K.J.11
White, C.L.12
Morris, J.C.13
Cairns, N.J.14
Goate, A.15
-
39
-
-
38349173569
-
Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion
-
Shankaran SS, Capell A, Hruscha AT, et al. Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. J Biol Chem 2008; 283: 1744-1753.
-
(2008)
J Biol Chem
, vol.283
, pp. 1744-1753
-
-
Shankaran, S.S.1
Capell, A.2
Hruscha, A.T.3
-
40
-
-
75949130374
-
Pathogenic cysteine mutations affect progranulin function and production of mature granulins
-
Wang J, Van Damme P, Cruchaga C, et al. Pathogenic cysteine mutations affect progranulin function and production of mature granulins. J Neurochem 2010; 112: 1305-1315.
-
(2010)
J Neurochem
, vol.112
, pp. 1305-1315
-
-
Wang, J.1
Van Damme, P.2
Cruchaga, C.3
-
41
-
-
35448929818
-
Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene
-
DOI 10.1016/j.bbr.2007.07.020, PII S0166432807003695
-
Kayasuga Y, Chiba S, Suzuki M, et al. Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene. Behav Brain Res 2007; 185: 110-118. (Pubitemid 47633696)
-
(2007)
Behavioural Brain Research
, vol.185
, Issue.2
, pp. 110-118
-
-
Kayasuga, Y.1
Chiba, S.2
Suzuki, M.3
Kikusui, T.4
Matsuwaki, T.5
Yamanouchi, K.6
Kotaki, H.7
Horai, R.8
Iwakura, Y.9
Nishihara, M.10
-
42
-
-
78149296002
-
Behavioral deficits and progressive neuropathology in progranulin-deficient mice: A mouse model of frontotemporal dementia
-
Yin F, Dumont M, Banerjee R, et al. Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia. FASEB J 2010; 24: 4639-4647.
-
(2010)
FASEB J
, vol.24
, pp. 4639-4647
-
-
Yin, F.1
Dumont, M.2
Banerjee, R.3
-
43
-
-
81955160693
-
Core features of frontotemporal dementia recapitulated in progranulin knockout mice
-
Ghoshal N, Dearborn JT, Wozniak DF, Cairns NJ,. Core features of frontotemporal dementia recapitulated in progranulin knockout mice. Neurobiol Dis 2012; 45: 395-408.
-
(2012)
Neurobiol Dis
, vol.45
, pp. 395-408
-
-
Ghoshal, N.1
Dearborn, J.T.2
Wozniak, D.F.3
Cairns, N.J.4
-
44
-
-
76149118401
-
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
-
Yin F, Banerjee R, Thomas B, et al. Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. J Exp Med 2010; 207: 117-128.
-
(2010)
J Exp Med
, vol.207
, pp. 117-128
-
-
Yin, F.1
Banerjee, R.2
Thomas, B.3
-
45
-
-
77954578417
-
Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging
-
Ahmed Z, Sheng H, Xu YF, et al. Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging. Am J Pathol 2010; 177: 311-324.
-
(2010)
Am J Pathol
, vol.177
, pp. 311-324
-
-
Ahmed, Z.1
Sheng, H.2
Xu, Y.F.3
-
46
-
-
79952712455
-
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
-
Kao AW, Eisenhut RJ, Martens LH, et al. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proc Natl Acad Sci U S A 2011; 108: 4441-4446.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 4441-4446
-
-
Kao, A.W.1
Eisenhut, R.J.2
Martens, L.H.3
-
47
-
-
79955477738
-
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice
-
Tang W, Lu Y, Tian QY, et al. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science 2011; 332: 478-484.
-
(2011)
Science
, vol.332
, pp. 478-484
-
-
Tang, W.1
Lu, Y.2
Tian, Q.Y.3
-
48
-
-
77955707871
-
Progranulin expression in the developing and adult murine brain
-
Petkau TL, Neal SJ, Orban PC, et al. Progranulin expression in the developing and adult murine brain. J Comp Neurol 2010; 518: 3931-3947.
-
(2010)
J Comp Neurol
, vol.518
, pp. 3931-3947
-
-
Petkau, T.L.1
Neal, S.J.2
Orban, P.C.3
-
49
-
-
84862134180
-
Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage
-
Smith KR, Damiano J, Franceschetti S, et al. Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage. Am J Hum Genet 2012; 90: 1102-1107.
-
(2012)
Am J Hum Genet
, vol.90
, pp. 1102-1107
-
-
Smith, K.R.1
Damiano, J.2
Franceschetti, S.3
-
50
-
-
1842483843
-
Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
-
DOI 10.1038/ng1332
-
Watts GD, Wymer J, Kovach MJ, et al. Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat Genet 2004; 36: 377-381. (Pubitemid 38437260)
-
(2004)
Nature Genetics
, vol.36
, Issue.4
, pp. 377-381
-
-
Watts, G.D.J.1
Wymer, J.2
Kovach, M.J.3
Mehta, S.G.4
Mumm, S.5
Darvish, D.6
Pestronk, A.7
Whyte, M.P.8
Kimonis, V.E.9
-
51
-
-
18244381306
-
Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: Hereditary inclusion body myopathy, paget disease of bone, and frontotemporal dementia
-
DOI 10.1006/mgme.2001.3256
-
Kovach MJ, Waggoner B, Leal SM, et al. Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy, Paget disease of bone, and frontotemporal dementia. Mol Genet Metab 2001; 74: 458-475. (Pubitemid 34084655)
-
(2001)
Molecular Genetics and Metabolism
, vol.74
, Issue.4
, pp. 458-475
-
-
Kovach, M.J.1
Waggoner, B.2
Leal, S.M.3
Gelber, D.4
Khardori, R.5
Levenstien, M.A.6
Shanks, C.A.7
Gregg, G.8
Al-Lozi, M.T.9
Miller, T.10
Rakowicz, W.11
Lopate, G.12
Florence, J.13
Glosser, G.14
Simmons, Z.15
Morris, J.C.16
Whyte, M.P.17
Pestronk, A.18
Kimonis, V.E.19
-
52
-
-
69449108742
-
Clinical heterogeneity in 3 unrelated families linked to VCP p.Arg159His
-
van der Zee J, Pirici D, Van Langenhove T, et al. Clinical heterogeneity in 3 unrelated families linked to VCP p.Arg159His. Neurology 2009; 73: 626-632.
-
(2009)
Neurology
, vol.73
, pp. 626-632
-
-
Van Der Zee, J.1
Pirici, D.2
Van Langenhove, T.3
-
53
-
-
79958699242
-
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia linked to VCP p.Arg155Cys in a Korean family
-
Kim EJ, Park YE, Kim DS, et al. Inclusion body myopathy with Paget disease of bone and frontotemporal dementia linked to VCP p.Arg155Cys in a Korean family. Arch Neurol 2011; 68: 787-796.
-
(2011)
Arch Neurol
, vol.68
, pp. 787-796
-
-
Kim, E.J.1
Park, Y.E.2
Kim, D.S.3
-
54
-
-
33746693220
-
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations
-
PII 0000507220060600000005
-
Forman MS, Mackenzie IR, Cairns NJ, et al. Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations. J Neuropathol Exp Neurol 2006; 65: 571-581. (Pubitemid 44288941)
-
(2006)
Journal of Neuropathology and Experimental Neurology
, vol.65
, Issue.6
, pp. 571-581
-
-
Forman, M.S.1
Mackenzie, I.R.2
Cairns, N.J.3
Swanson, E.4
Boyer, P.J.5
Drachman, D.A.6
Jhaveri, B.S.7
Karlawish, J.H.8
Pestronk, A.9
Smith, T.W.10
Tu, P.-H.11
Watts, G.D.J.12
Markesbery, W.R.13
Smith, C.D.14
Kimonis, V.E.15
-
55
-
-
33846506651
-
Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality
-
DOI 10.1016/j.bbrc.2006.12.206, PII S0006291X07000083
-
Müller JM, Deinhardt K, Rosewell I, et al. Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality. Biochem Biophys Res Commun 2007; 354: 459-465. (Pubitemid 46161346)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.354
, Issue.2
, pp. 459-465
-
-
Muller, J.M.M.1
Deinhardt, K.2
Rosewell, I.3
Warren, G.4
Shima, D.T.5
-
56
-
-
35348909072
-
Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia
-
DOI 10.1111/j.1399-0004.2007.00887.x
-
Watts GD, Thomasova D, Ramdeen SK, et al. Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia. Clin Genet 2007; 72: 420-426. (Pubitemid 47570695)
-
(2007)
Clinical Genetics
, vol.72
, Issue.5
, pp. 420-426
-
-
Watts, G.D.G.1
Thomasova, D.2
Ramdeen, S.K.3
Fulchiero, E.C.4
Mehta, S.G.5
Drachman, D.A.6
Weihl, C.C.7
Jamrozik, Z.8
Kwiecinski, H.9
Kaminska, A.10
Kimonis, V.E.11
-
57
-
-
77953894192
-
Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: A disorder of autophagy
-
Ju JS, Weihl CC,. Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy. Hum Mol Genet 2010; 19: R38-R45.
-
(2010)
Hum Mol Genet
, vol.19
-
-
Ju, J.S.1
Weihl, C.C.2
-
58
-
-
77952486387
-
Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone
-
Custer SK, Neumann M, Lu H, et al. Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone. Hum Mol Genet 2010; 19: 1741-1755.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 1741-1755
-
-
Custer, S.K.1
Neumann, M.2
Lu, H.3
-
59
-
-
78049244477
-
VCP associated inclusion body myopathy and Paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease
-
Badadani M, Nalbandian A, Watts GD, et al. VCP associated inclusion body myopathy and Paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease. PLoS One 2010; 5: e13183.
-
(2010)
PLoS One
, vol.5
-
-
Badadani, M.1
Nalbandian, A.2
Watts, G.D.3
-
60
-
-
0037180476
-
Chromosome 3 linked frontotemporal dementia (FTD-3)
-
Gydesen S, Brown JM, Brun A, et al. Chromosome 3 linked frontotemporal dementia (FTD-3). Neurology 2002; 59: 1585-1594. (Pubitemid 35387067)
-
(2002)
Neurology
, vol.59
, Issue.10
, pp. 1585-1594
-
-
Gydesen, S.1
Brown, J.M.2
Brun, A.3
Chakrabarti, L.4
Gade, A.5
Johannsen, P.6
Rossor, M.7
Thusgaard, T.8
Grove, A.9
Yancopoulou, D.10
Spillantini, M.G.11
Fisher, E.M.C.12
Collinge, J.13
Sorensen, S.A.14
-
61
-
-
79956277415
-
Frontotemporal dementia caused by CHMP2B mutations
-
Isaacs AM, Johannsen P, Holm I, et al. Frontotemporal dementia caused by CHMP2B mutations. Curr Alzheimer Res 2011; 8: 246-251.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 246-251
-
-
Isaacs, A.M.1
Johannsen, P.2
Holm, I.3
-
62
-
-
34948838317
-
A reassessment of the neuropathology of frontotemporal dementia linked to chromosome 3
-
DOI 10.1097/nen.0b013e3181567f02, PII 0000507220071000000002
-
Holm IE, Englund E, Mackenzie IR, et al. A reassessment of the neuropathology of frontotemporal dementia linked to chromosome 3. J Neuropathol Exp Neurol 2007; 66: 884-891. (Pubitemid 47530827)
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.10
, pp. 884-891
-
-
Holm, I.E.1
Englund, E.2
Mackenzie, I.R.A.3
Johannsen, P.4
Isaacs, A.M.5
-
63
-
-
70449517337
-
Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene
-
Holm IE, Isaacs AM, Mackenzie IR,. Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene. Acta Neuropathol 2009; 118: 719-720.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 719-720
-
-
Holm, I.E.1
Isaacs, A.M.2
MacKenzie, I.R.3
-
64
-
-
77956392186
-
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)
-
Cox LE, Ferraiuolo L, Goodall EF, et al. Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS). PLoS One 2010; 5: e9872.
-
(2010)
PLoS One
, vol.5
-
-
Cox, L.E.1
Ferraiuolo, L.2
Goodall, E.F.3
-
65
-
-
23044471011
-
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
-
DOI 10.1038/ng1609
-
Skibinski G, Parkinson NJ, Brown JM, et al. Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nat Genet 2005; 37: 806-808. (Pubitemid 41077105)
-
(2005)
Nature Genetics
, vol.37
, Issue.8
, pp. 806-808
-
-
Skibinski, G.1
Parkinson, N.J.2
Brown, J.M.3
Chakrabarti, L.4
Lloyd, S.L.5
Hummerich, H.6
Nielsen, J.E.7
Hodges, J.R.8
Spillantini, M.G.9
Thusgaard, T.10
Brandner, S.11
Brun, A.12
Rossor, M.N.13
Gade, A.14
Johannsen, P.15
Sorensen, S.A.16
Gydesen, S.17
Fisher, E.M.C.18
Collinge, J.19
-
66
-
-
34548492271
-
ESCRT-III Dysfunction Causes Autophagosome Accumulation and Neurodegeneration
-
DOI 10.1016/j.cub.2007.07.029, PII S0960982207017071
-
Lee JA, Beigneux A, Ahmad ST, et al. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr Biol 2007; 17: 1561-1567. (Pubitemid 47380392)
-
(2007)
Current Biology
, vol.17
, Issue.18
, pp. 1561-1567
-
-
Lee, J.-A.1
Beigneux, A.2
Ahmad, S.T.3
Young, S.G.4
Gao, F.-B.5
-
67
-
-
84857568926
-
Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice
-
Ghazi-Noori S, Froud KE, Mizielinska S, et al. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain 2012; 135: 819-832.
-
(2012)
Brain
, vol.135
, pp. 819-832
-
-
Ghazi-Noori, S.1
Froud, K.E.2
Mizielinska, S.3
-
69
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
DeJesus-Hernandez M, Mackenzie IR, Boeve BF, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011; 72: 245-256.
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
Dejesus-Hernandez, M.1
MacKenzie, I.R.2
Boeve, B.F.3
-
70
-
-
33847194237
-
Hereditary frontotemporal dementia caused by Tau gene mutations
-
van Swieten J, Spillantini MG,. Hereditary frontotemporal dementia caused by Tau gene mutations. Brain Pathol 2007; 17: 63-73.
-
(2007)
Brain Pathol
, vol.17
, pp. 63-73
-
-
Van Swieten, J.1
Spillantini, M.G.2
-
71
-
-
33144463940
-
Global hairpin folding of tau in solution
-
DOI 10.1021/bi0521543
-
Jeganathan S, von Bergen M, Brutlach H, et al. Global hairpin folding of tau in solution. Biochemistry 2006; 45: 2283-2293. (Pubitemid 43271328)
-
(2006)
Biochemistry
, vol.45
, Issue.7
, pp. 2283-2293
-
-
Jeganathan, S.1
Von Bergen, M.2
Brutlach, H.3
Steinhoff, H.-J.4
Mandelkow, E.5
-
72
-
-
5044235577
-
The role of tau (MAPT) in frontotemporal dementia and related tauopathies
-
DOI 10.1002/humu.20086
-
Rademakers R, Cruts M, van Broeckhoven C,. The role of tau (MAPT) in frontotemporal dementia and related tauopathies. Hum Mutat 2004; 24: 277-295. (Pubitemid 39336634)
-
(2004)
Human Mutation
, vol.24
, Issue.4
, pp. 277-295
-
-
Rademakers, R.1
Cruts, M.2
Van Broeckhoven, C.3
-
74
-
-
33847199377
-
A decade of tau transgenic animal models and beyond
-
Götz J, Deters N, Doldissen A, et al. A decade of tau transgenic animal models and beyond. Brain Pathol 2007; 17: 91-103.
-
(2007)
Brain Pathol
, vol.17
, pp. 91-103
-
-
Götz, J.1
Deters, N.2
Doldissen, A.3
-
75
-
-
20044367108
-
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
-
DOI 10.1523/JNEUROSCI.4637-04.2005
-
Andorfer C, Acker CM, Kress Y, et al. Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci 2005; 25: 5446-5454. (Pubitemid 40770926)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.22
, pp. 5446-5454
-
-
Andorfer, C.1
Acker, C.M.2
Kress, Y.3
Hof, P.R.4
Duff, K.5
Davies, P.6
-
76
-
-
33646519920
-
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
-
Spires TL, Orne JD, SantaCruz K, et al. Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy. Am J Pathol 2006; 168: 1598-1607.
-
(2006)
Am J Pathol
, vol.168
, pp. 1598-1607
-
-
Spires, T.L.1
Orne, J.D.2
Santacruz, K.3
-
77
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
de Calignon A, Fox LM, Pitstick R, et al. Caspase activation precedes and leads to tangles. Nature 2010; 464: 1201-1204.
-
(2010)
Nature
, vol.464
, pp. 1201-1204
-
-
De Calignon, A.1
Fox, L.M.2
Pitstick, R.3
-
78
-
-
38549129613
-
The potential for β-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
-
DOI 10.1523/JNEUROSCI.2824-07.2008
-
Mocanu MM, Nissen A, Eckermann K, et al. The potential for β-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous tau in inducible mouse models of tauopathy. J Neurosci 2008; 28: 737-748. (Pubitemid 351159036)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.3
, pp. 737-748
-
-
Mocanu, M.-M.1
Nissen, A.2
Eckermann, K.3
Khlistunova, I.4
Biernat, J.5
Drexler, D.6
Petrova, O.7
Schonig, K.8
Bujard, H.9
Mandelkow, E.10
Zhou, L.11
Rune, G.12
Mandelkow, E.-M.13
-
79
-
-
33846538660
-
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
-
DOI 10.1016/j.neuron.2007.01.010, PII S089662730700030X
-
Yoshiyama Y, Higuchi M, Zhang B, et al. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 2007; 53: 337-351. (Pubitemid 46161268)
-
(2007)
Neuron
, vol.53
, Issue.3
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.-M.4
Iwata, N.5
Saido, TakaomiC.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.-Y.10
-
80
-
-
22344438508
-
Medicine: Tau suppression in a neurodegenerative mouse model improves memory function
-
DOI 10.1126/science.1113694
-
Santacruz K, Lewis J, Spires T, et al. Tau suppression in a neurodegenerative mouse model improves memory function. Science 2005; 309: 476-481. (Pubitemid 40994688)
-
(2005)
Science
, vol.309
, Issue.5733
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McCowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
81
-
-
79951818085
-
Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant
-
Sydow A, Van der Jeugd A, Zheng F, et al. Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant. J Neurosci 2011; 31: 2511-2525.
-
(2011)
J Neurosci
, vol.31
, pp. 2511-2525
-
-
Sydow, A.1
Van Der Jeugd, A.2
Zheng, F.3
-
82
-
-
78650251838
-
Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration
-
Hoover BR, Reed MN, Su J, et al. Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron 2010; 68: 1067-1081.
-
(2010)
Neuron
, vol.68
, pp. 1067-1081
-
-
Hoover, B.R.1
Reed, M.N.2
Su, J.3
-
83
-
-
84863337784
-
Predicting regional neurodegeneration from the healthy brain functional connectome
-
Zhou J, Gennatas ED, Kramer JH, et al. Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron 2012; 73: 1216-1227.
-
(2012)
Neuron
, vol.73
, pp. 1216-1227
-
-
Zhou, J.1
Gennatas, E.D.2
Kramer, J.H.3
-
84
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost B, Jacks RL, Diamond MI,. Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem 2009; 284: 12845-12852.
-
(2009)
J Biol Chem
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
85
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera F, Bolmont T, Crowther RA, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol 2009; 11: 909-913.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
-
86
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
de Calignon A, Polydoro M, Suárez-Calvet M, et al. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 2012; 73: 685-697.
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
De Calignon, A.1
Polydoro, M.2
Suárez-Calvet, M.3
-
87
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu L, Drouet V, Wu JW, et al. Trans-synaptic spread of tau pathology in vivo. PLoS One 2012; 7: e31302.
-
(2012)
PLoS One
, vol.7
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
-
88
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
DOI 10.1073/pnas.0500466102
-
Noble W, Planel E, Zehr C, et al. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc Natl Acad Sci U S A 2005; 102: 6990-6995. (Pubitemid 40675429)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.19
, pp. 6990-6995
-
-
Noble, W.1
Planel, E.2
Zehr, C.3
Olm, V.4
Meyerson, J.5
Suleman, F.6
Gaynor, K.7
Wang, L.8
LaFrancois, J.9
Feinstein, B.10
Burns, M.11
Krishnamurthy, P.12
Wen, Y.13
Bhat, R.14
Lewis, J.15
Dickson, D.16
Duff, K.17
-
89
-
-
33745449875
-
An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice
-
DOI 10.1073/pnas.0602913103
-
Le Corre S, Klafki HW, Plesnila N, et al. An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice. Proc Natl Acad Sci U S A 2006; 103: 9673-9678. (Pubitemid 43955883)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.25
, pp. 9673-9678
-
-
Le Corre, S.1
Klafki, H.W.2
Plesnila, N.3
Hubinger, G.4
Obermeier, A.5
Sahagun, H.6
Monse, B.7
Seneci, P.8
Lewis, J.9
Eriksen, J.10
Zehr, C.11
Yue, M.12
McGowan, E.13
Dickson, D.W.14
Hutton, M.15
Roder, H.M.16
-
90
-
-
77958065504
-
Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy
-
Brunden KR, Zhang B, Carroll J, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci 2010; 30: 13861-13866.
-
(2010)
J Neurosci
, vol.30
, pp. 13861-13866
-
-
Brunden, K.R.1
Zhang, B.2
Carroll, J.3
-
91
-
-
34548146119
-
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
-
DOI 10.1523/JNEUROSCI.2361-07.2007
-
Asuni AA, Boutajangout A, Quartermain D, Sigurdsson EM,. Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements. J Neurosci 2007; 27: 9115-9129. (Pubitemid 47312068)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.34
, pp. 9115-9129
-
-
Asuni, A.A.1
Boutajangout, A.2
Quartermain, D.3
Sigurdsson, E.M.4
-
92
-
-
80053202160
-
Passive immunization with anti-Tau antibodies in two transgenic models: Reduction of Tau pathology and delay of disease progression
-
Chai X, Wu S, Murray TK, et al. Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression. J Biol Chem 2011; 286: 34457-34467.
-
(2011)
J Biol Chem
, vol.286
, pp. 34457-34467
-
-
Chai, X.1
Wu, S.2
Murray, T.K.3
-
93
-
-
82955194797
-
Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice
-
Bi M, Ittner A, Ke YD, et al. Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice. PLoS One 2011; 6: e26860.
-
(2011)
PLoS One
, vol.6
-
-
Bi, M.1
Ittner, A.2
Ke, Y.D.3
-
94
-
-
77958566761
-
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
-
O'Leary JC III, Li Q, Marinec P, et al. Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden. Mol Neurodegener 2010; 5: 45.
-
(2010)
Mol Neurodegener
, vol.5
, pp. 45
-
-
O'Leary Iii, J.C.1
Li, Q.2
Marinec, P.3
-
95
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
Renton AE, Majounie E, Waite A, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011; 72: 257-268.
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
-
96
-
-
84857612209
-
Familial frontotemporal dementia and amyotrophic lateral sclerosis associated with the C9ORF72 hexanucleotide repeat
-
Hodges J,. Familial frontotemporal dementia and amyotrophic lateral sclerosis associated with the C9ORF72 hexanucleotide repeat. Brain 2012; 135: 652-655.
-
(2012)
Brain
, vol.135
, pp. 652-655
-
-
Hodges, J.1
-
97
-
-
84863251089
-
Rat brains also have a default mode network
-
Lu H, Zou Q, Gu H, et al. Rat brains also have a default mode network. Proc Natl Acad Sci U S A 2012; 109: 3979-3984.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 3979-3984
-
-
Lu, H.1
Zou, Q.2
Gu, H.3
-
98
-
-
70349274112
-
Evolution of the neocortex: A perspective from developmental biology
-
Rakic P,. Evolution of the neocortex: a perspective from developmental biology. Nat Rev Neurosci 2009; 10: 724-735.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 724-735
-
-
Rakic, P.1
-
99
-
-
10044251348
-
Frontotemporal dementia as a neural system disease
-
DOI 10.1016/j.neurobiolaging.2004.02.019, PII S0197458004001228
-
Boccardi M, Sabattoli F, Laakso MP, et al. Frontotemporal dementia as a neural system disease. Neurobiol Aging 2005; 26: 37-44. (Pubitemid 39600589)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.1
, pp. 37-44
-
-
Boccardi, M.1
Sabattoli, F.2
Laakso, M.P.3
Testa, C.4
Rossi, R.5
Beltramello, A.6
Soininen, H.7
Frisoni, G.B.8
-
100
-
-
37349009196
-
Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia
-
DOI 10.1001/archneurol.2007.38
-
Seeley WW, Crawford R, Rascovsky K, et al. Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia. Arch Neurol 2008; 65: 249-255. (Pubitemid 351240789)
-
(2008)
Archives of Neurology
, vol.65
, Issue.2
, pp. 249-255
-
-
Seeley, W.W.1
Crawford, R.2
Rascovsky, K.3
Kramer, J.H.4
Weiner, M.5
Miller, B.L.6
Gorno-Tempini, M.L.7
-
101
-
-
38949104395
-
Neural networks in frontotemporal dementia-A meta-analysis
-
DOI 10.1016/j.neurobiolaging.2006.10.023, PII S0197458006003939
-
Schroeter ML, Raczka K, Neumann J, von Cramon DY,. Neural networks in frontotemporal dementia-a meta-analysis. Neurobiol Aging 2008; 29: 418-426. (Pubitemid 351215583)
-
(2008)
Neurobiology of Aging
, vol.29
, Issue.3
, pp. 418-426
-
-
Schroeter, M.L.1
Raczka, K.2
Neumann, J.3
Von Cramon, D.Y.4
-
102
-
-
33847343843
-
Dissociable intrinsic connectivity networks for salience processing and executive control
-
DOI 10.1523/JNEUROSCI.5587-06.2007
-
Seeley WW, Menon V, Schatzberg AF, et al. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 2007; 27: 2349-2356. (Pubitemid 46340968)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.9
, pp. 2349-2356
-
-
Seeley, W.W.1
Menon, V.2
Schatzberg, A.F.3
Keller, J.4
Glover, G.H.5
Kenna, H.6
Reiss, A.L.7
Greicius, M.D.8
-
103
-
-
69249122462
-
Two systems of resting state connectivity between the insula and cingulate cortex
-
Taylor KS, Seminowicz DA, Davis KD,. Two systems of resting state connectivity between the insula and cingulate cortex. Hum Brain Mapp 2009; 30: 2731-2745.
-
(2009)
Hum Brain Mapp
, vol.30
, pp. 2731-2745
-
-
Taylor, K.S.1
Seminowicz, D.A.2
Davis, K.D.3
-
105
-
-
57549117980
-
Ventral pallidum roles in reward and motivation
-
Smith KS, Tindell AJ, Aldridge JW, Berridge KC,. Ventral pallidum roles in reward and motivation. Behav Brain Res 2009; 196: 155-167.
-
(2009)
Behav Brain Res
, vol.196
, pp. 155-167
-
-
Smith, K.S.1
Tindell, A.J.2
Aldridge, J.W.3
Berridge, K.C.4
-
106
-
-
35348858152
-
The amygdala
-
LeDoux J,. The amygdala. Curr Biol 2007; 17: R868-R874.
-
(2007)
Curr Biol
, vol.17
-
-
Ledoux, J.1
-
107
-
-
85027933622
-
The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans
-
Allman JM, Tetreault NA, Hakeem AY, et al. The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans. Brain Struct Funct 2010; 214: 495-517.
-
(2010)
Brain Struct Funct
, vol.214
, pp. 495-517
-
-
Allman, J.M.1
Tetreault, N.A.2
Hakeem, A.Y.3
-
108
-
-
0031672540
-
Frontotemporal lobar degeneration: A consensus on clinical diagnostic criteria
-
Neary D, Snowden JS, Gustafson L, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998; 51: 1546-1554.
-
(1998)
Neurology
, vol.51
, pp. 1546-1554
-
-
Neary, D.1
Snowden, J.S.2
Gustafson, L.3
-
109
-
-
80052938441
-
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
-
Rascovsky K, Hodges JR, Knopman D, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 2011; 134 (pt 9): 2456-2477.
-
(2011)
Brain
, vol.134
, Issue.PART 9
, pp. 2456-2477
-
-
Rascovsky, K.1
Hodges, J.R.2
Knopman, D.3
-
110
-
-
35148821488
-
Mouse behavioral assays relevant to the symptoms of autism
-
DOI 10.1111/j.1750-3639.2007.00096.x
-
Crawley JN,. Mouse behavioral assays relevant to the symptoms of autism. Brain Pathol 2007; 17: 448-459. (Pubitemid 47537604)
-
(2007)
Brain Pathology
, vol.17
, Issue.4
, pp. 448-459
-
-
Crawley, J.N.1
-
111
-
-
4644373224
-
Sociability and preference for social novelty in five inbred strains: An approach to assess autistic-like behavior in mice
-
DOI 10.1111/j.1601-1848.2004.00076.x
-
Moy SS, Nadler JJ, Perez A, et al. Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice. Genes Brain Behav 2004; 3: 287-302. (Pubitemid 39277416)
-
(2004)
Genes, Brain and Behavior
, vol.3
, Issue.5
, pp. 287-302
-
-
Moy, S.S.1
Nadler, J.J.2
Perez, A.3
Barbaro, R.P.4
Johns, J.M.5
Magnuson, T.R.6
Piven, J.7
Crawley, J.N.8
-
112
-
-
33745620162
-
Social modulation of pain as evidence for empathy in mice
-
DOI 10.1126/science.1128322
-
Langford DJ, Crager SE, Shehzad Z, et al. Social modulation of pain as evidence for empathy in mice. Science 2006; 312: 1967-1970. (Pubitemid 43993726)
-
(2006)
Science
, vol.312
, Issue.5782
, pp. 1967-1970
-
-
Langford, D.J.1
Crager, S.E.2
Shehzad, Z.3
Smith, S.B.4
Sotocinal, S.G.5
Levenstadt, J.S.6
Chanda, M.L.7
Levitin, D.J.8
Mogil, J.S.9
-
113
-
-
77950188817
-
Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC
-
Jeon D, Kim S, Chetana M, et al. Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC. Nat Neurosci 2010; 13: 482-488.
-
(2010)
Nat Neurosci
, vol.13
, pp. 482-488
-
-
Jeon, D.1
Kim, S.2
Chetana, M.3
-
114
-
-
0037469226
-
Double dissociation of social functioning in frontotemporal dementia
-
Rankin KP, Kramer JH, Mychack P, Miller BL,. Double dissociation of social functioning in frontotemporal dementia. Neurology 2003; 60: 266-271. (Pubitemid 36152020)
-
(2003)
Neurology
, vol.60
, Issue.2
, pp. 266-271
-
-
Rankin, K.P.1
Kramer, J.H.2
Mychack, P.3
Miller, B.L.4
-
115
-
-
0000145720
-
Social dominance in inbred mouse strains
-
Lindzey G, Winston H, Manosevitz M,. Social dominance in inbred mouse strains. Nature 1961; 191: 474-476.
-
(1961)
Nature
, vol.191
, pp. 474-476
-
-
Lindzey, G.1
Winston, H.2
Manosevitz, M.3
-
116
-
-
33750594405
-
Structural anatomy of empathy in neurodegenerative disease
-
DOI 10.1093/brain/awl254
-
Rankin KP, Gorno-Tempini ML, Allison SC, et al. Structural anatomy of empathy in neurodegenerative disease. Brain 2006; 129: 2945-2956. (Pubitemid 44684515)
-
(2006)
Brain
, vol.129
, Issue.11
, pp. 2945-2956
-
-
Rankin, K.P.1
Gorno-Tempini, M.L.2
Allison, S.C.3
Stanley, C.M.4
Glenn, S.5
Weiner, M.W.6
Miller, B.L.7
-
117
-
-
41749100596
-
Abnormal social behaviors in mice lacking Fgf17
-
DOI 10.1111/j.1601-183X.2007.00357.x
-
Scearce-Levie K, Roberson ED, Gerstein H, et al. Abnormal social behaviors in mice lacking Fgf17. Genes Brain Behav 2008; 7: 344-354. (Pubitemid 351490238)
-
(2008)
Genes, Brain and Behavior
, vol.7
, Issue.3
, pp. 344-354
-
-
Scearce-Levie, K.1
Roberson, E.D.2
Gerstein, H.3
Cholfin, J.A.4
Mandiyan, V.S.5
Shah, N.M.6
Rubenstein, J.L.R.7
Mucke, L.8
-
118
-
-
0029017613
-
Dietary changes, compulsions and sexual behavior in frontotemporal degeneration
-
Miller BL, Darby AL, Swartz JR, et al. Dietary changes, compulsions and sexual behavior in frontotemporal degeneration. Dementia 1995; 6: 195-199.
-
(1995)
Dementia
, vol.6
, pp. 195-199
-
-
Miller, B.L.1
Darby, A.L.2
Swartz, J.R.3
-
119
-
-
22844432332
-
Stereotypical movements and frontotemporal dementia
-
DOI 10.1002/mds.20465
-
Mendez MF, Shapira JS, Miller BL,. Stereotypical movements and frontotemporal dementia. Mov Disord 2005; 20: 742-745. (Pubitemid 41051787)
-
(2005)
Movement Disorders
, vol.20
, Issue.6
, pp. 742-745
-
-
Mendez, M.F.1
Shapira, J.S.2
Miller, B.L.3
-
120
-
-
0037012082
-
Hoxb8 Is Required for Normal Grooming Behavior in Mice
-
DOI 10.1016/S0896-6273(01)00564-5
-
Greer JM, Capecchi MR,. Hoxb8 is required for normal grooming behavior in mice. Neuron 2002; 33: 23-34. (Pubitemid 34088176)
-
(2002)
Neuron
, vol.33
, Issue.1
, pp. 23-34
-
-
Greer, J.M.1
Capecchi, M.R.2
-
121
-
-
34548147472
-
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice
-
DOI 10.1038/nature06104, PII NATURE06104
-
Welch JM, Lu J, Rodriguiz RM, et al. Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature 2007; 448: 894-900. (Pubitemid 47312780)
-
(2007)
Nature
, vol.448
, Issue.7156
, pp. 894-900
-
-
Welch, J.M.1
Lu, J.2
Rodriguiz, R.M.3
Trotta, N.C.4
Peca, J.5
Ding, J.-D.6
Feliciano, C.7
Chen, M.8
Adams, J.P.9
Luo, J.10
Dudek, S.M.11
Weinberg, R.J.12
Calakos, N.13
Wetsel, W.C.14
Feng, G.15
-
122
-
-
77952243965
-
Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice
-
Shmelkov SV, Hormigo A, Jing D, et al. Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice. Nat Med 2010; 16: 598-602.
-
(2010)
Nat Med
, vol.16
, pp. 598-602
-
-
Shmelkov, S.V.1
Hormigo, A.2
Jing, D.3
-
123
-
-
53649096105
-
Anatomic correlates of stereotypies in frontotemporal lobar degeneration
-
Josephs KA, Whitwell JL, Jack CR Jr,. Anatomic correlates of stereotypies in frontotemporal lobar degeneration. Neurobiol Aging 2008; 29: 1859-1863.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1859-1863
-
-
Josephs, K.A.1
Whitwell, J.L.2
Jack, Jr.C.R.3
-
124
-
-
84874225352
-
Patterns of striatal degeneration in frontotemporal dementia
-
. doi: 10.1097/WAD.0b013e31824a7df4.
-
Halabi C, Halabi A, Dean DL, et al. Patterns of striatal degeneration in frontotemporal dementia. Alzheimer Dis Assoc Disord. doi: 10.1097/WAD. 0b013e31824a7df4.
-
Alzheimer Dis Assoc Disord.
-
-
Halabi, C.1
Halabi, A.2
Dean, D.L.3
-
125
-
-
34447340926
-
Emotional reactivity and emotion recognition in frontotemporal lobar degeneration
-
DOI 10.1212/01.wnl.0000265589.32060.d3, PII 0000611420070710000005
-
Werner KH, Roberts NA, Rosen HJ, et al. Emotional reactivity and emotion recognition in frontotemporal lobar degeneration. Neurology 2007; 69: 148-155. (Pubitemid 47051719)
-
(2007)
Neurology
, vol.69
, Issue.2
, pp. 148-155
-
-
Werner, K.H.1
Roberts, N.A.2
Rosen, H.J.3
Dean, D.L.4
Kramer, J.H.5
Weiner, M.W.6
Miller, B.L.7
Levenson, R.W.8
-
126
-
-
44949087532
-
Fear conditioning in frontotemporal lobar degeneration and Alzheimer's disease
-
DOI 10.1093/brain/awn082
-
Hoefer M, Allison SC, Schauer GF, et al. Fear conditioning in frontotemporal lobar degeneration and Alzheimer's disease. Brain 2008; 131: 1646-1657. (Pubitemid 351806464)
-
(2008)
Brain
, vol.131
, Issue.6
, pp. 1646-1657
-
-
Hoefer, M.1
Allison, S.C.2
Schauer, G.F.3
Neuhaus, J.M.4
Hall, J.5
Dang, J.N.6
Weiner, M.W.7
Miller, B.L.8
Rosen, H.J.9
-
127
-
-
0042317090
-
The emotional brain, fear, and the amygdala
-
LeDoux J,. The emotional brain, fear, and the amygdala. Cell Mol Neurobiol 2003; 23: 727-738.
-
(2003)
Cell Mol Neurobiol
, vol.23
, pp. 727-738
-
-
Ledoux, J.1
-
128
-
-
70350338847
-
Of mice and men: Bridging the translational disconnect in CNS drug discovery
-
Geerts H,. Of mice and men: bridging the translational disconnect in CNS drug discovery. CNS Drugs 2009; 23: 915-926.
-
(2009)
CNS Drugs
, vol.23
, pp. 915-926
-
-
Geerts, H.1
-
129
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L)tau protein
-
DOI 10.1038/78078
-
Lewis J, McGowan E, Rockwood J, et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat Genet 2000; 25: 402-405. (Pubitemid 32983430)
-
(2000)
Nature Genetics
, vol.25
, Issue.4
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Murphy, M.P.8
Baker, M.9
Yu, X.10
Duff, K.11
Hardy, J.12
Corral, A.13
Lin, W.-L.14
Yen, S.-H.15
Dickson, D.W.16
Davies, P.17
Hutton, M.18
-
130
-
-
27944491109
-
Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)
-
DOI 10.1523/JNEUROSCI.3279-05.2005
-
Ramsden M, Kotilinek L, Forster C, et al. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L). J Neurosci 2005; 25: 10637-10647. (Pubitemid 41681911)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.46
, pp. 10637-10647
-
-
Ramsden, M.1
Kotilinek, L.2
Forster, C.3
Paulson, J.4
McGowan, E.5
SantaCruz, K.6
Guimaraes, A.7
Yue, M.8
Lewis, J.9
Carlson, G.10
Hutton, M.11
Ashe, K.H.12
-
131
-
-
0035808361
-
Tau filament formation in transgenic mice expressing P301L tau
-
DOI 10.1074/jbc.M006531200
-
Götz J, Chen F, Barmettler R, Nitsch RM,. Tau filament formation in transgenic mice expressing P301L tau. J Biol Chem 2001; 276: 529-534. (Pubitemid 32050347)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.1
, pp. 529-534
-
-
Gotz, J.1
Chen, F.2
Barmettler, R.3
Nitsch, R.M.4
-
132
-
-
0034016093
-
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes
-
DOI 10.1006/nbdi.1999.0279
-
Duff K, Knight H, Refolo LM, et al. Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes. Neurobiol Dis 2000; 7: 87-98. (Pubitemid 30241205)
-
(2000)
Neurobiology of Disease
, vol.7
, Issue.2
, pp. 87-98
-
-
Duff, K.1
Knight, H.2
Refolo, L.M.3
Sanders, S.4
Yu, X.5
Picciano, M.6
Malester, B.7
Hutton, M.8
Adamson, J.9
Goedert, M.10
Burki, K.11
Davies, P.12
-
133
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
DOI 10.1046/j.1471-4159.2003.01879.x
-
Andorfer C, Kress Y, Espinoza M, et al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem 2003; 86: 582-590. (Pubitemid 36897439)
-
(2003)
Journal of Neurochemistry
, vol.86
, Issue.3
, pp. 582-590
-
-
Andorfer, C.1
Kress, Y.2
Espinoza, M.3
De Silva, R.4
Tucker, K.L.5
Barde, Y.-A.6
Duff, K.7
Davies, P.8
|