-
1
-
-
77950938389
-
Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments
-
Bernard, H.U.; Burk, R.D.; Chen, Z.; van Doorslaer, K.; Hausen, H.; de Villiers, E.M. Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments. Virology 2010, 401, 70-79.
-
(2010)
Virology
, vol.401
, pp. 70-79
-
-
Bernard, H.U.1
Burk, R.D.2
Chen, Z.3
van Doorslaer, K.4
Hausen, H.5
de Villiers, E.M.6
-
2
-
-
77954955259
-
Human papillomavirus oncoproteins: Pathways to transformation
-
Moody, C.A.; Laimins, L.A. Human papillomavirus oncoproteins: Pathways to transformation. Nat. Rev. Cancer 2010, 10, 550-560.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 550-560
-
-
Moody, C.A.1
Laimins, L.A.2
-
3
-
-
0037421589
-
Epidemiologic classification of human papillomavirus types associated with cervical cancer
-
Munoz, N.; Bosch, F.X.; de Sanjose, S.; Herrero, R.; Castellsague, X.; Shah, K.V.; Snijders, P.J.; Meijer, C.J. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N. Engl. J. Med. 2003, 348, 518-527.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 518-527
-
-
Munoz, N.1
Bosch, F.X.2
de Sanjose, S.3
Herrero, R.4
Castellsague, X.5
Shah, K.V.6
Snijders, P.J.7
Meijer, C.J.8
-
4
-
-
84873606312
-
Annual report to the nation on the status of cancer, 1975-2009, Featuring the burden and trends in human papillomavirus(HPV)-associated cancers and HPV vaccination coverage levels
-
Jemal, A.; Simard, E.P.; Dorell, C.; Noone, A.M.; Markowitz, L.E.; Kohler, B.; Eheman, C.; Saraiya, M.; Bandi, P.; Saslow, D. et al. Annual report to the nation on the status of cancer, 1975-2009, Featuring the burden and trends in human papillomavirus(HPV)-associated cancers and HPV vaccination coverage levels. J. Nat. Cancer Inst. 2013, 105, 175-201.
-
(2013)
J. Nat. Cancer Inst
, vol.105
, pp. 175-201
-
-
Jemal, A.1
Simard, E.P.2
Dorell, C.3
Noone, A.M.4
Markowitz, L.E.5
Kohler, B.6
Eheman, C.7
Saraiya, M.8
Bandi, P.9
Saslow, D.10
-
5
-
-
84877074785
-
Implementation of human papillomavirus immunization in the developing world
-
Kane, M.A.; Serrano, B.; de Sanjose, S.; Wittet, S. Implementation of human papillomavirus immunization in the developing world. Vaccine 2012, 30 (Suppl. 5), F192-F200.
-
(2012)
Vaccine
, vol.30
, Issue.SUPPL. 5
-
-
Kane, M.A.1
Serrano, B.2
de Sanjose, S.3
Wittet, S.4
-
6
-
-
0345827680
-
Prevention of cervical cancer through papillomavirus vaccination
-
Frazer, I.H. Prevention of cervical cancer through papillomavirus vaccination. Nat. Rev. Immunol. 2004, 4, 46-54.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 46-54
-
-
Frazer, I.H.1
-
7
-
-
33645211201
-
Human papillomaviruses: Basic mechanisms of pathogenesis and oncogenicity
-
Hebner, C.M.; Laimins, L.A. Human papillomaviruses: Basic mechanisms of pathogenesis and oncogenicity. Rev. Med. Virol. 2006, 16, 83-97.
-
(2006)
Rev. Med. Virol
, vol.16
, pp. 83-97
-
-
Hebner, C.M.1
Laimins, L.A.2
-
8
-
-
78650748371
-
Persistence of human papillomavirus infection: Keys to malignant progression
-
Bodily, J.; Laimins, L.A. Persistence of human papillomavirus infection: Keys to malignant progression. Trends Microbiol. 2011, 19, 33-39.
-
(2011)
Trends Microbiol
, vol.19
, pp. 33-39
-
-
Bodily, J.1
Laimins, L.A.2
-
9
-
-
0023144684
-
Structural and translational analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
-
Baker, C.C.; Phelps, W.C.; Lindgren, V.; Braun, M.J.; Gonda, M.A.; Howley, P.M. Structural and translational analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J. Virol. 1987, 61, 962-971.
-
(1987)
J. Virol
, vol.61
, pp. 962-971
-
-
Baker, C.C.1
Phelps, W.C.2
Lindgren, V.3
Braun, M.J.4
Gonda, M.A.5
Howley, P.M.6
-
10
-
-
0021986880
-
Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
-
Schwarz, E.; Freese, U.K.; Gissmann, L.; Mayer, W.; Roggenbuck, B.; Stremlau, A.; Zur Hausen, H. Structure and transcription of human papillomavirus sequences in cervical carcinoma cells. Nature 1985, 314, 111-114.
-
(1985)
Nature
, vol.314
, pp. 111-114
-
-
Schwarz, E.1
Freese, U.K.2
Gissmann, L.3
Mayer, W.4
Roggenbuck, B.5
Stremlau, A.6
Zur, H.H.7
-
11
-
-
68949194550
-
Oncogenic activities of human papillomaviruses
-
McLaughlin-Drubin, M.E.; Munger, K. Oncogenic activities of human papillomaviruses. Virus Res. 2009, 143, 195-208.
-
(2009)
Virus Res
, vol.143
, pp. 195-208
-
-
McLaughlin-Drubin, M.E.1
Munger, K.2
-
12
-
-
0042440926
-
Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis
-
Riley, R.R.; Duensing, S.; Brake, T.; Munger, K.; Lambert, P.F.; Arbeit, J.M. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res. 2003, 63, 4862-4871.
-
(2003)
Cancer Res
, vol.63
, pp. 4862-4871
-
-
Riley, R.R.1
Duensing, S.2
Brake, T.3
Munger, K.4
Lambert, P.F.5
Arbeit, J.M.6
-
13
-
-
0342948594
-
Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells
-
Francis, D.A.; Schmid, S.I.; Howley, P.M. Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells. J. Virol. 2000, 74, 2679-2686.
-
(2000)
J. Virol
, vol.74
, pp. 2679-2686
-
-
Francis, D.A.1
Schmid, S.I.2
Howley, P.M.3
-
14
-
-
0033740178
-
Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways
-
Goodwin, E.C.; DiMaio, D. Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways. Proc. Natl. Acad. Sci. USA 2000, 97, 12513-81251.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12513-81251
-
-
Goodwin, E.C.1
Dimaio, D.2
-
15
-
-
0023441712
-
The BPV-1 E2 trans-acting protein can be either an activator or repressor of the HPV-18 regulatory region
-
Thierry, F.; Yaniv, M. The BPV-1 E2 trans-acting protein can be either an activator or repressor of the HPV-18 regulatory region. EMBO 1987, 6, 3391-3397.
-
(1987)
EMBO
, vol.6
, pp. 3391-3397
-
-
Thierry, F.1
Yaniv, M.2
-
16
-
-
70350500219
-
Polycomb group proteins: Navigators of lineage pathways led astray in cancer
-
Bracken, A.P.; Helin, K. Polycomb group proteins: Navigators of lineage pathways led astray in cancer. Nat. Rev. Cancer 2009, 9, 773-784.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 773-784
-
-
Bracken, A.P.1
Helin, K.2
-
17
-
-
79955972412
-
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure
-
Trojer, P.; Cao, A.R.; Gao, Z.; Li, Y.; Zhang, J.; Xu, X.; Li, G.; Losson, R.; Erdjument-Bromage, H.; Tempst, P. et al. L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure. Mol. Cell 2011, 42, 438-450.
-
(2011)
Mol. Cell
, vol.42
, pp. 438-450
-
-
Trojer, P.1
Cao, A.R.2
Gao, Z.3
Li, Y.4
Zhang, J.5
Xu, X.6
Li, G.7
Losson, R.8
Erdjument-Bromage, H.9
Tempst, P.10
-
18
-
-
84866139087
-
The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development
-
Qin, J.; Whyte, W.A.; Anderssen, E.; Apostolou, E.; Chen, H.H.; Akbarian, S.; Bronson, R.T.; Hochedlinger, K.; Ramaswamy, S.; Young, R.A. et al. The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell 2012, 11, 319-332.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 319-332
-
-
Qin, J.1
Whyte, W.A.2
Anderssen, E.3
Apostolou, E.4
Chen, H.H.5
Akbarian, S.6
Bronson, R.T.7
Hochedlinger, K.8
Ramaswamy, S.9
Young, R.A.10
-
19
-
-
84862894023
-
Epigenetic regulation of skin: Focus on the Polycomb complex
-
Zhang, J.; Bardot, E.; Ezhkova, E. Epigenetic regulation of skin: Focus on the Polycomb complex. Cell Mol. Life Sci. 2012, 69, 2161-2172.
-
(2012)
Cell Mol. Life Sci
, vol.69
, pp. 2161-2172
-
-
Zhang, J.1
Bardot, E.2
Ezhkova, E.3
-
20
-
-
78651402346
-
Polycomb group proteins are key regulators of keratinocyte function
-
Eckert, R.L.; Adhikary, G.; Rorke, E.A.; Chew, Y.C.; Balasubramanian, S. Polycomb group proteins are key regulators of keratinocyte function. J. Invest. Dermatol. 2011, 131, 295-301.
-
(2011)
J. Invest. Dermatol
, vol.131
, pp. 295-301
-
-
Eckert, R.L.1
Adhikary, G.2
Rorke, E.A.3
Chew, Y.C.4
Balasubramanian, S.5
-
21
-
-
68249128477
-
Epigenetic reprogramming during wound healing: Loss of polycomb-mediated silencing may enable upregulation of repair genes
-
Shaw, T.; Martin, P. Epigenetic reprogramming during wound healing: Loss of polycomb-mediated silencing may enable upregulation of repair genes. EMBO Rep. 2009, 10, 881-886.
-
(2009)
EMBO Rep
, vol.10
, pp. 881-886
-
-
Shaw, T.1
Martin, P.2
-
22
-
-
83255191898
-
The role of Hox proteins in leukemogenesis: Insights into key regulatory events in hematopoiesis
-
Eklund, E. The role of Hox proteins in leukemogenesis: Insights into key regulatory events in hematopoiesis. Crit. Rev. Oncog. 2011, 16, 65-76.
-
(2011)
Crit. Rev. Oncog
, vol.16
, pp. 65-76
-
-
Eklund, E.1
-
23
-
-
80052561657
-
HOX genes in ovarian cancer
-
Kelly, Z.L.; Michael, A.; Butler-Manuel, S.; Pandha, H.S.; Morgan, R.G. HOX genes in ovarian cancer. J. Ovarian. Res. 2011, 4, e16.
-
(2011)
J. Ovarian. Res
, vol.4
-
-
Kelly, Z.L.1
Michael, A.2
Butler-Manuel, S.3
Pandha, H.S.4
Morgan, R.G.5
-
24
-
-
84856176782
-
Germline mutations in HOXB13 and prostate-cancer risk
-
Ewing, C.M.; Ray, A.M.; Lange, E.M.; Zuhlke, K.A.; Robbins, C.M.; Tembe, W.D.; Wiley, K.E.; Isaacs, S.D.; Johng, D.; Wang, Y. et al. Germline mutations in HOXB13 and prostate-cancer risk. N. Engl. J. Med. 2012, 366, 141-149.
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 141-149
-
-
Ewing, C.M.1
Ray, A.M.2
Lange, E.M.3
Zuhlke, K.A.4
Robbins, C.M.5
Tembe, W.D.6
Wiley, K.E.7
Isaacs, S.D.8
Johng, D.9
Wang, Y.10
-
25
-
-
84875921843
-
Interplay between homeobox proteins and polycomb repressive complexes in p16 regulation
-
Martin, N.; Popov, N.; Aguilo, F.; O'Loghlen, A.; Raguz, S.; Snijders, A.P.; Dharmalingam, G.; Li, S.; Thymiakou, E.; Carroll, T. et al. Interplay between homeobox proteins and polycomb repressive complexes in p16 regulation. EMBO 2013, 32, 982-995
-
(2013)
EMBO
, vol.32
, pp. 982-995
-
-
Martin, N.1
Popov, N.2
Aguilo, F.3
O'Loghlen, A.4
Raguz, S.5
Snijders, A.P.6
Dharmalingam, G.7
Li, S.8
Thymiakou, E.9
Carroll, T.10
-
26
-
-
0037743898
-
Homeobox gene expression and mutation in cervical carcinoma cells
-
Hung, Y.C.; Ueda, M.; Terai, Y.; Kumagai, K.; Ueki, K.; Kanda, K.; Yamaguchi, H.; Akise, D.; Ueki, M. Homeobox gene expression and mutation in cervical carcinoma cells. Cancer Sci. 2003, 94, 437-441.
-
(2003)
Cancer Sci
, vol.94
, pp. 437-441
-
-
Hung, Y.C.1
Ueda, M.2
Terai, Y.3
Kumagai, K.4
Ueki, K.5
Kanda, K.6
Yamaguchi, H.7
Akise, D.8
Ueki, M.9
-
27
-
-
0033590974
-
HOXC5 and HOXC8 expression are selectively turned on in human cervical cancer cells compared to normal keratinocytes
-
Alami, Y.; Castronovo, V.; Belotti, D.; Flagiello, D.; Clausse, N. HOXC5 and HOXC8 expression are selectively turned on in human cervical cancer cells compared to normal keratinocytes. Biochem. Biophys. Res. Commun. 1999, 257, 738-745.
-
(1999)
Biochem. Biophys. Res. Commun
, vol.257
, pp. 738-745
-
-
Alami, Y.1
Castronovo, V.2
Belotti, D.3
Flagiello, D.4
Clausse, N.5
-
28
-
-
84857036615
-
Hox B4 as potential marker of non-differentiated cells in human cervical cancer cells
-
Barba-de Rosa A. P., Briones-Cerecero E., Lugo-Melchor O., de Leon-Rodriguez A., Santos L., Castelo-Ruelas J., Valdivia A., Pina P., Chagolla-Lopez A., Hernandez-Cueto D. et al. Hox B4 as potential marker of non-differentiated cells in human cervical cancer cells. J. Cancer Res. Clin. Oncol. 2012, 138, 293-300.
-
(2012)
J. Cancer Res. Clin. Oncol
, vol.138
, pp. 293-300
-
-
Barba-De, R.A.P.1
Briones-Cerecero, E.2
Lugo-Melchor, O.3
de Leon-Rodriguez, A.4
Santos, L.5
Castelo-Ruelas, J.6
Valdivia, A.7
Pina, P.8
Chagolla-Lopez, A.9
Hernandez-Cueto, D.10
-
29
-
-
35948969388
-
Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion
-
Zhai, Y.; Kuick, R.; Nan, B.; Ota, I.; Weiss, S.J.; Trimble, C.L.; Fearon, E.R.; Cho, K.R. Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Res. 2007, 67, 10163-10172.
-
(2007)
Cancer Res
, vol.67
, pp. 10163-10172
-
-
Zhai, Y.1
Kuick, R.2
Nan, B.3
Ota, I.4
Weiss, S.J.5
Trimble, C.L.6
Fearon, E.R.7
Cho, K.R.8
-
30
-
-
84870725909
-
Proteomic approaches to the study of papillomavirus-host interactions
-
White, E.A.; Howley, P.M. Proteomic approaches to the study of papillomavirus-host interactions. Virology 2013, 435, 57-69.
-
(2013)
Virology
, vol.435
, pp. 57-69
-
-
White, E.A.1
Howley, P.M.2
-
31
-
-
23844456912
-
Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600
-
Huh, K.W.; DeMasi, J.; Ogawa, H.; Nakatani, Y.; Howley, P.M.; Munger, K. Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600. Proc. Natl. Acad. Sci. USA 2005, 102, 11492-11497.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11492-11497
-
-
Huh, K.W.1
Demasi, J.2
Ogawa, H.3
Nakatani, Y.4
Howley, P.M.5
Munger, K.6
-
32
-
-
50149100141
-
Human papillomavirus type 16 E7 oncoprotein associates with E2F6
-
McLaughlin-Drubin, M.E.; Huh, K.W.; Munger, K. Human papillomavirus type 16 E7 oncoprotein associates with E2F6. J. Virol. 2008, 82, 8695-8705.
-
(2008)
J. Virol
, vol.82
, pp. 8695-8705
-
-
McLaughlin-Drubin, M.E.1
Huh, K.W.2
Munger, K.3
-
33
-
-
0032490832
-
E2F-6: A novel member of the E2F family is an inhibitor of E2F-dependent transcription
-
Cartwright, P.; Muller, H.; Wagener, C.; Holm, K.; Helin, K. E2F-6: A novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 1998, 17, 611-623.
-
(1998)
Oncogene
, vol.17
, pp. 611-623
-
-
Cartwright, P.1
Muller, H.2
Wagener, C.3
Holm, K.4
Helin, K.5
-
34
-
-
0032482981
-
Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6
-
Gaubatz, S.; Wood, J.G.; Livingston, D.M. Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc. Natl. Acad. Sci. USA 1998, 95, 9190-9195.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9190-9195
-
-
Gaubatz, S.1
Wood, J.G.2
Livingston, D.M.3
-
35
-
-
0035852632
-
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
-
Trimarchi, J.M.; Fairchild, B.; Wen, J.; Lees, J.A. The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc. Natl. Acad. Sci. USA 2001, 98, 1519-1524.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1519-1524
-
-
Trimarchi, J.M.1
Fairchild, B.2
Wen, J.3
Lees, J.A.4
-
36
-
-
0037052539
-
A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
-
Ogawa, H.; Ishiguro, K.; Gaubatz, S.; Livingston, D.M.; Nakatani, Y. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science 2002, 296, 1132-1136.
-
(2002)
Science
, vol.296
, pp. 1132-1136
-
-
Ogawa, H.1
Ishiguro, K.2
Gaubatz, S.3
Livingston, D.M.4
Nakatani, Y.5
-
37
-
-
19944431321
-
A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner
-
Attwooll, C.; Oddi, S.; Cartwright, P.; Prosperini, E.; Agger, K.; Steensgaard, P.; Wagener, C.; Sardet, C.; Moroni, M.C.; Helin, K. A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner. J. Biol. Chem. 2005, 280, 1199-1208.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 1199-1208
-
-
Attwooll, C.1
Oddi, S.2
Cartwright, P.3
Prosperini, E.4
Agger, K.5
Steensgaard, P.6
Wagener, C.7
Sardet, C.8
Moroni, M.C.9
Helin, K.10
-
38
-
-
33947253984
-
PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors
-
Deshpande, A.M.; Akunowicz, J.D.; Reveles, X.T.; Patel, B.B.; Saria, E.A.; Gorlick, R.G.; Naylor, S.L.; Leach, R.J.; Hansen, M.F. PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors. Oncogene 2007, 26, 1714-1722.
-
(2007)
Oncogene
, vol.26
, pp. 1714-1722
-
-
Deshpande, A.M.1
Akunowicz, J.D.2
Reveles, X.T.3
Patel, B.B.4
Saria, E.A.5
Gorlick, R.G.6
Naylor, S.L.7
Leach, R.J.8
Hansen, M.F.9
-
39
-
-
79952140358
-
Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming
-
McLaughlin-Drubin, M.E.; Crum, C.P.; Munger, K. Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming. Proc. Natl. Acad. Sci. USA 2011, 108, 2130-2135.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2130-2135
-
-
McLaughlin-Drubin, M.E.1
Crum, C.P.2
Munger, K.3
-
40
-
-
80055108218
-
Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes
-
Hyland, P.L.; McDade, S.S.; McCloskey, R.; Dickson, G.J.; Arthur, K.; McCance, D.J.; Patel, D. Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. J. Virol. 2011, 85, 10999-11006.
-
(2011)
J. Virol
, vol.85
, pp. 10999-11006
-
-
Hyland, P.L.1
McDade, S.S.2
McCloskey, R.3
Dickson, G.J.4
Arthur, K.5
McCance, D.J.6
Patel, D.7
-
41
-
-
0142105414
-
EZH2 is downstream of the pRB-E2F pathway, Essential for proliferation and amplified in cancer
-
Bracken, A.P.; Pasini, D.; Capra, M.; Prosperini, E.; Colli, E.; Helin, K. EZH2 is downstream of the pRB-E2F pathway, Essential for proliferation and amplified in cancer. EMBO J. 2003, 22, 5323-5335.
-
(2003)
EMBO J
, vol.22
, pp. 5323-5335
-
-
Bracken, A.P.1
Pasini, D.2
Capra, M.3
Prosperini, E.4
Colli, E.5
Helin, K.6
-
42
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin, R.D.; Johnson, N.A.; Severson, T.M.; Mungall, A.J.; An, J.; Goya, R.; Paul, J.E.; Boyle, M.; Woolcock, B.W.; Kuchenbauer, F. et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat. Genet. 2010, 42, 181-185.
-
(2010)
Nat. Genet
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
Mungall, A.J.4
An, J.5
Goya, R.6
Paul, J.E.7
Boyle, M.8
Woolcock, B.W.9
Kuchenbauer, F.10
-
43
-
-
79955513100
-
Aberrations of EZH2 in cancer
-
Chase, A.; Cross, N.C. Aberrations of EZH2 in cancer. Clin. Cancer Res. 2011, 17, 2613-2618.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 2613-2618
-
-
Chase, A.1
Cross, N.C.2
-
44
-
-
57149107384
-
Activation of the enhancer of zeste homologue 2 gene by the human papillomavirus E7 oncoprotein
-
Holland, D.; Hoppe-Seyler, K.; Schuller, B.; Lohrey, C.; Maroldt, J.; Durst, M.; Hoppe-Seyler, F. Activation of the enhancer of zeste homologue 2 gene by the human papillomavirus E7 oncoprotein. Cancer Res. 2008, 68, 9964-9972.
-
(2008)
Cancer Res
, vol.68
, pp. 9964-9972
-
-
Holland, D.1
Hoppe-Seyler, K.2
Schuller, B.3
Lohrey, C.4
Maroldt, J.5
Durst, M.6
Hoppe-Seyler, F.7
-
45
-
-
26844520965
-
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
-
Cha, T.L.; Zhou, B.P.; Xia, W.; Wu, Y.; Yang, C.C.; Chen, C.T.; Ping, B.; Otte, A.P.; Hung, M.C. Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science 2005, 310, 306-310.
-
(2005)
Science
, vol.310
, pp. 306-310
-
-
Cha, T.L.1
Zhou, B.P.2
Xia, W.3
Wu, Y.4
Yang, C.C.5
Chen, C.T.6
Ping, B.7
Otte, A.P.8
Hung, M.C.9
-
46
-
-
33745241083
-
Human papillomavirus type 16 E7 up-regulates AKT activity through the retinoblastoma protein
-
Menges, C.W.; Baglia, L.A.; Lapoint, R.; McCance, D.J. Human papillomavirus type 16 E7 up-regulates AKT activity through the retinoblastoma protein. Cancer Res. 2006, 66, 5555-5559.
-
(2006)
Cancer Res
, vol.66
, pp. 5555-5559
-
-
Menges, C.W.1
Baglia, L.A.2
Lapoint, R.3
McCance, D.J.4
-
47
-
-
77956024826
-
The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis
-
Spangle, J.M.; Munger, K. The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. J. Virol. 2010, 84, 9398-9407.
-
(2010)
J. Virol
, vol.84
, pp. 9398-9407
-
-
Spangle, J.M.1
Munger, K.2
-
48
-
-
84871052080
-
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
-
Xu, K.; Wu, Z.J.; Groner, A.C.; He, H.H.; Cai, C.; Lis, R.T.; Wu, X.; Stack, E.C.; Loda, M.; Liu, T. et al. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science 2012, 338, 1465-1469.
-
(2012)
Science
, vol.338
, pp. 1465-1469
-
-
Xu, K.1
Wu, Z.J.2
Groner, A.C.3
He, H.H.4
Cai, C.5
Lis, R.T.6
Wu, X.7
Stack, E.C.8
Loda, M.9
Liu, T.10
-
49
-
-
13844315463
-
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation
-
Kuzmichev, A.; Margueron, R.; Vaquero, A.; Preissner, T.S.; Scher, M.; Kirmizis, A.; Ouyang, X.; Brockdorff, N.; Abate-Shen, C.; Farnham, P. et al. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc. Natl. Acad. Sci. USA 2005, 102, 1859-1864.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1859-1864
-
-
Kuzmichev, A.1
Margueron, R.2
Vaquero, A.3
Preissner, T.S.4
Scher, M.5
Kirmizis, A.6
Ouyang, X.7
Brockdorff, N.8
Abate-Shen, C.9
Farnham, P.10
-
50
-
-
77954600171
-
Overexpression of polycomb protein BMI-1 in human specimens of breast, Ovarian, endometrial and cervical cancer
-
Honig, A.; Weidler, C.; Hausler, S.; Krockenberger, M.; Buchholz, S.; Koster, F.; Segerer, S.E.; Dietl, J.; Engel, J.B. Overexpression of polycomb protein BMI-1 in human specimens of breast, Ovarian, endometrial and cervical cancer. Anticancer Res. 2010, 30, 1559-1564.
-
(2010)
Anticancer Res
, vol.30
, pp. 1559-1564
-
-
Honig, A.1
Weidler, C.2
Hausler, S.3
Krockenberger, M.4
Buchholz, S.5
Koster, F.6
Segerer, S.E.7
Dietl, J.8
Engel, J.B.9
-
51
-
-
79959829390
-
Clinicopathological and prognostic significance of Bmi-1 expression in human cervical cancer
-
Min, L.; Dong-Xiang, S.; Xiao-Tong, G.; Ting, G.; Xiao-Dong, C. Clinicopathological and prognostic significance of Bmi-1 expression in human cervical cancer. Acta Obstet. Gynecol. Scand. 2011, 90, 737-745.
-
(2011)
Acta Obstet. Gynecol. Scand
, vol.90
, pp. 737-745
-
-
Min, L.1
Dong-Xiang, S.2
Xiao-Tong, G.3
Ting, G.4
Xiao-Dong, C.5
-
52
-
-
84875338713
-
Overexpression of Bmi-1 in uterine cervical cancer: Correlation with clinicopathology and prognosis
-
Zhang, X.; Wang, C.X.; Zhu, C.B.; Zhang, J.; Kan, S.F.; Du, L.T.; Li, W.; Wang, L.L.; Wang, S. Overexpression of Bmi-1 in uterine cervical cancer: Correlation with clinicopathology and prognosis. Int. J. Gynecol. Cancer 2010, 20, 1597-1603.
-
(2010)
Int. J. Gynecol. Cancer
, vol.20
, pp. 1597-1603
-
-
Zhang, X.1
Wang, C.X.2
Zhu, C.B.3
Zhang, J.4
Kan, S.F.5
Du, L.T.6
Li, W.7
Wang, L.L.8
Wang, S.9
-
53
-
-
84860222900
-
Detection of circulating Bmi-1 mRNA in plasma and its potential diagnostic and prognostic value for uterine cervical cancer
-
Zhang, X.; Wang, C.; Wang, L.; Du, L.; Wang, S.; Zheng, G.; Li, W.; Zhuang, X.; Dong, Z. Detection of circulating Bmi-1 mRNA in plasma and its potential diagnostic and prognostic value for uterine cervical cancer. Int. J. Cancer 2012, 131, 165-172.
-
(2012)
Int. J. Cancer
, vol.131
, pp. 165-172
-
-
Zhang, X.1
Wang, C.2
Wang, L.3
Du, L.4
Wang, S.5
Zheng, G.6
Li, W.7
Zhuang, X.8
Dong, Z.9
-
54
-
-
81455140663
-
BMI-1 autoantibody as a new potential biomarker for cervical carcinoma
-
Tong, Y.Q.; Liu, B.; Zheng, H.Y.; He, Y.J.; Gu, J.; Li, F.; Li, Y. BMI-1 autoantibody as a new potential biomarker for cervical carcinoma. PLoS One 2011, 6, e27804.
-
(2011)
PLoS One
, vol.6
-
-
Tong, Y.Q.1
Liu, B.2
Zheng, H.Y.3
He, Y.J.4
Gu, J.5
Li, F.6
Li, Y.7
-
55
-
-
84876817779
-
HPV16 E7 Protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytes
-
Miller, J.; Dakic, A.; Chen, R.; Palechor-Ceron, N.; Dai, Y.; Kallakury, B.; Schlegel, R.; Liu, X. HPV16 E7 Protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytes. PLoS Pathog. 2013, 9, e1003284.
-
(2013)
PLoS Pathog
, vol.9
-
-
Miller, J.1
Dakic, A.2
Chen, R.3
Palechor-Ceron, N.4
Dai, Y.5
Kallakury, B.6
Schlegel, R.7
Liu, X.8
-
56
-
-
84655170252
-
Knockdown of BMI-1 causes cell-cycle arrest and derepresses p16INK4a, HOXA9 and HOXC13 mRNA expression in HeLa cells
-
Chen, F.; Li, Y.; Wang, L.; Hu, L. Knockdown of BMI-1 causes cell-cycle arrest and derepresses p16INK4a, HOXA9 and HOXC13 mRNA expression in HeLa cells. Med. Oncol. 2011, 28, 1201-1209.
-
(2011)
Med. Oncol
, vol.28
, pp. 1201-1209
-
-
Chen, F.1
Li, Y.2
Wang, L.3
Hu, L.4
-
57
-
-
6844242334
-
The UTX gene escapes X inactivation in mice and humans
-
Greenfield, A.; Carrel, L.; Pennisi, D.; Philippe, C.; Quaderi, N.; Siggers, P.; Steiner, K.; Tam, P.P.; Monaco, A.P.; Willard, H.F. et al. The UTX gene escapes X inactivation in mice and humans. Hum. Mol. Genet. 1998, 7, 737-742.
-
(1998)
Hum. Mol. Genet
, vol.7
, pp. 737-742
-
-
Greenfield, A.1
Carrel, L.2
Pennisi, D.3
Philippe, C.4
Quaderi, N.5
Siggers, P.6
Steiner, K.7
Tam, P.P.8
Monaco, A.P.9
Willard, H.F.10
-
58
-
-
84866912634
-
UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development
-
Shpargel, K.B.; Sengoku, T.; Yokoyama, S.; Magnuson, T. UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012, 8, e1002964.
-
(2012)
PLoS Genet
, vol.8
-
-
Shpargel, K.B.1
Sengoku, T.2
Yokoyama, S.3
Magnuson, T.4
-
59
-
-
84855957128
-
UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program
-
Lee, S.; Lee, J.W.; Lee, S.K. UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program. Dev. Cell 2012, 22, 25-37.
-
(2012)
Dev. Cell
, vol.22
, pp. 25-37
-
-
Lee, S.1
Lee, J.W.2
Lee, S.K.3
-
60
-
-
84864663969
-
X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner
-
Welstead, G.G.; Creyghton, M.P.; Bilodeau, S.; Cheng, A.W.; Markoulaki, S.; Young, R.A.; Jaenisch, R. X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner. Proc. Natl. Acad. Sci. USA 2012, 109, 13004-13009.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 13004-13009
-
-
Welstead, G.G.1
Creyghton, M.P.2
Bilodeau, S.3
Cheng, A.W.4
Markoulaki, S.5
Young, R.A.6
Jaenisch, R.7
-
61
-
-
84866530722
-
Regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity
-
Wang, C.; Lee, J.E.; Cho, Y.W.; Xiao, Y.; Jin, Q.; Liu, C.; Ge, K. UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity. Proc. Natl. Acad. Sci. USA 2012, 109, 15324-15329.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 15324-15329
-
-
Wang, C.1
Lee, J.E.2
Cho, Y.W.3
Xiao, Y.4
Jin, Q.5
Liu, C.6
Ge, K.U.T.X.7
-
62
-
-
84870400666
-
The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, Neonatal breathing, and survival
-
Burgold, T.; Voituron, N.; Caganova, M.; Tripathi, P.P.; Menuet, C.; Tusi, B.K.; Spreafico, F.; Bevengut, M.; Gestreau, C.; Buontempo, S. et al. The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, Neonatal breathing, and survival. Cell Rep. 2012, 2, 1244-1258.
-
(2012)
Cell Rep
, vol.2
, pp. 1244-1258
-
-
Burgold, T.1
Voituron, N.2
Caganova, M.3
Tripathi, P.P.4
Menuet, C.5
Tusi, B.K.6
Spreafico, F.7
Bevengut, M.8
Gestreau, C.9
Buontempo, S.10
-
63
-
-
34548644772
-
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
De Santa, F.; Totaro, M.G.; Prosperini, E.; Notarbartolo, S.; Testa, G.; Natoli, G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007, 130, 1083-1094.
-
(2007)
Cell
, vol.130
, pp. 1083-1094
-
-
de Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
64
-
-
70350754328
-
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
-
De Santa, F.; Narang, V.; Yap, Z.H.; Tusi, B.K.; Burgold, T.; Austenaa, L.; Bucci, G.; Caganova, M.; Notarbartolo, S.; Casola, S. et al. Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. EMBO 2009, 28, 3341-3352.
-
(2009)
EMBO
, vol.28
, pp. 3341-3352
-
-
de Santa, F.1
Narang, V.2
Yap, Z.H.3
Tusi, B.K.4
Burgold, T.5
Austenaa, L.6
Bucci, G.7
Caganova, M.8
Notarbartolo, S.9
Casola, S.10
-
65
-
-
35348993743
-
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
-
Lee, M.G.; Villa, R.; Trojer, P.; Norman, J.; Yan, K.P.; Reinberg, D.; Di Croce, L.; Shiekhattar, R. Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science 2007, 318, 447-450.
-
(2007)
Science
, vol.318
, pp. 447-450
-
-
Lee, M.G.1
Villa, R.2
Trojer, P.3
Norman, J.4
Yan, K.P.5
Reinberg, D.6
Di, C.L.7
Shiekhattar, R.8
-
66
-
-
33847219608
-
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
-
Issaeva, I.; Zonis, Y.; Rozovskaia, T.; Orlovsky, K.; Croce, C.M.; Nakamura, T.; Mazo, A.; Eisenbach, L.; Canaani, E. Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth. Mol. Cell Biol. 2007, 27, 1889-1903.
-
(2007)
Mol. Cell Biol
, vol.27
, pp. 1889-1903
-
-
Issaeva, I.1
Zonis, Y.2
Rozovskaia, T.3
Orlovsky, K.4
Croce, C.M.5
Nakamura, T.6
Mazo, A.7
Eisenbach, L.8
Canaani, E.9
-
67
-
-
67349203626
-
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
-
van Haaften, G.; Dalgliesh, G.L.; Davies, H.; Chen, L.; Bignell, G.; Greenman, C.; Edkins, S.; Hardy, C.; O'Meara, S.; Teague, J. et al. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat. Genet. 2009, 41, 521-523.
-
(2009)
Nat. Genet
, vol.41
, pp. 521-523
-
-
van Haaften, G.1
Dalgliesh, G.L.2
Davies, H.3
Chen, L.4
Bignell, G.5
Greenman, C.6
Edkins, S.7
Hardy, C.8
O'Meara, S.9
Teague, J.10
-
68
-
-
35348826654
-
JMJD3 is a histone H3K27 demethylase
-
Xiang, Y.; Zhu, Z.; Han, G.; Lin, H.; Xu, L.; Chen, C.D. JMJD3 is a histone H3K27 demethylase. Cell Res. 2007, 17, 850-857.
-
(2007)
Cell Res
, vol.17
, pp. 850-857
-
-
Xiang, Y.1
Zhu, Z.2
Han, G.3
Lin, H.4
Xu, L.5
Chen, C.D.6
-
69
-
-
47549105128
-
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
-
Sen, G.L.; Webster, D.E.; Barragan, D.I.; Chang, H.Y.; Khavari, P.A. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Gene. Develop. 2008, 22, 1865-1870.
-
(2008)
Gene. Develop
, vol.22
, pp. 1865-1870
-
-
Sen, G.L.1
Webster, D.E.2
Barragan, D.I.3
Chang, H.Y.4
Khavari, P.A.5
-
70
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M.; Lin, A.W.; McCurrach, M.E.; Beach, D.; Lowe, S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
71
-
-
66149135288
-
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
-
Barradas, M.; Anderton, E.; Acosta, J.C.; Li, S.; Banito, A.; Rodriguez-Niedenfuhr, M.; Maertens, G.; Banck, M.; Zhou, M.M.; Walsh, M.J. et al. Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Gene. Develop. 2009, 23, 1177-1182.
-
(2009)
Gene. Develop
, vol.23
, pp. 1177-1182
-
-
Barradas, M.1
Anderton, E.2
Acosta, J.C.3
Li, S.4
Banito, A.5
Rodriguez-Niedenfuhr, M.6
Maertens, G.7
Banck, M.8
Zhou, M.M.9
Walsh, M.J.10
-
72
-
-
66149138053
-
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
-
Agger, K.; Cloos, P.A.; Rudkjaer, L.; Williams, K.; Andersen, G.; Christensen, J.; Helin, K. The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence. Gene. Develop. 2009, 23, 1171-1176.
-
(2009)
Gene. Develop
, vol.23
, pp. 1171-1176
-
-
Agger, K.1
Cloos, P.A.2
Rudkjaer, L.3
Williams, K.4
Andersen, G.5
Christensen, J.6
Helin, K.7
-
73
-
-
0031740497
-
Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
-
Sano, T.; Oyama, T.; Kashiwabara, K.; Fukuda, T.; Nakajima, T. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Amer. J. Pathol. 1998, 153, 1741-1748.
-
(1998)
Amer. J. Pathol
, vol.153
, pp. 1741-1748
-
-
Sano, T.1
Oyama, T.2
Kashiwabara, K.3
Fukuda, T.4
Nakajima, T.5
-
74
-
-
0035871985
-
Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri
-
Klaes, R.; Friedrich, T.; Spitkovsky, D.; Ridder, R.; Rudy, W.; Petry, U.; Dallenbach-Hellweg, G.; Schmidt, D.; von Knebel Doeberitz, M. Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int. J. Cancer 2001, 92, 276-284.
-
(2001)
Int. J. Cancer
, vol.92
, pp. 276-284
-
-
Klaes, R.1
Friedrich, T.2
Spitkovsky, D.3
Ridder, R.4
Rudy, W.5
Petry, U.6
Dallenbach-Hellweg, G.7
Schmidt, D.8
von Knebel Doeberitz, M.9
-
75
-
-
0029975913
-
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity
-
Khleif, S.N.; DeGregori, J.; Yee, C.L.; Otterson, G.A.; Kaye, F.J.; Nevins, J.R.; Howley, P.M. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc. Natl. Acad. Sci. USA 1996, 93, 4350-4354.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4350-4354
-
-
Khleif, S.N.1
Degregori, J.2
Yee, C.L.3
Otterson, G.A.4
Kaye, F.J.5
Nevins, J.R.6
Howley, P.M.7
-
76
-
-
0034899522
-
Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7
-
Gonzalez, S.L.; Stremlau, M.; He, X.; Basile, J.R.; Münger, K. Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7. J. Virol. 2001, 75, 7583-7591.
-
(2001)
J. Virol
, vol.75
, pp. 7583-7591
-
-
Gonzalez, S.L.1
Stremlau, M.2
He, X.3
Basile, J.R.4
Münger, K.5
-
77
-
-
84874772161
-
Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr Virus (EBV) transforms primary B cells into lymphoblastoid cell lines
-
Skalska, L.; White, R.E.; Parker, G.A.; Sinclair, A.J.; Paschos, K.; Allday, M.J. Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr Virus (EBV) transforms primary B cells into lymphoblastoid cell lines. PLoS Pathog. 2013, 9, e1003187.
-
(2013)
PLoS Pathog
, vol.9
-
-
Skalska, L.1
White, R.E.2
Parker, G.A.3
Sinclair, A.J.4
Paschos, K.5
Allday, M.J.6
-
78
-
-
77954664053
-
Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP
-
Skalska, L.; White, R.E.; Franz, M.; Ruhmann, M.; Allday, M.J. Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP. PLoS Pathog. 2010, 6, e1000951.
-
(2010)
PLoS Pathog
, vol.6
-
-
Skalska, L.1
White, R.E.2
Franz, M.3
Ruhmann, M.4
Allday, M.J.5
-
79
-
-
78649746843
-
Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification
-
White, R.E.; Groves, I.J.; Turro, E.; Yee, J.; Kremmer, E.; Allday, M.J. Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification. PLoS One 2010, 5, e13979.
-
(2010)
PLoS One
, vol.5
-
-
White, R.E.1
Groves, I.J.2
Turro, E.3
Yee, J.4
Kremmer, E.5
Allday, M.J.6
-
80
-
-
84867288340
-
BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV
-
Paschos, K.; Parker, G.A.; Watanatanasup, E.; White, R.E.; Allday, M.J. BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV. Nucleic Acids Res. 2012, 40, 7233-7246.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 7233-7246
-
-
Paschos, K.1
Parker, G.A.2
Watanatanasup, E.3
White, R.E.4
Allday, M.J.5
-
81
-
-
84875347265
-
Deregulation of epigenetic mechanisms by the hepatitis B virus x protein in hepatocarcinogenesis
-
Andrisani, O.M. Deregulation of epigenetic mechanisms by the hepatitis B virus x protein in hepatocarcinogenesis. Viruses 2013, 5, 858-872.
-
(2013)
Viruses
, vol.5
, pp. 858-872
-
-
Andrisani, O.M.1
-
82
-
-
59449086167
-
The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas
-
Herschkowitz, J.I.; He, X.; Fan, C.; Perou, C.M. The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas. Breast Cancer Res. 2008, 10, R75.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Herschkowitz, J.I.1
He, X.2
Fan, C.3
Perou, C.M.4
-
83
-
-
0037191509
-
Alterations in the p16/pRb cell cycle checkpoint occur commonly in primary and metastatic human prostate cancer
-
Jarrard, D.F.; Modder, J.; Fadden, P.; Fu, V.; Sebree, L.; Heisey, D.; Schwarze, S.R.; Friedl, A. Alterations in the p16/pRb cell cycle checkpoint occur commonly in primary and metastatic human prostate cancer. Cancer Lett. 2002, 185, 191-199.
-
(2002)
Cancer Lett
, vol.185
, pp. 191-199
-
-
Jarrard, D.F.1
Modder, J.2
Fadden, P.3
Fu, V.4
Sebree, L.5
Heisey, D.6
Schwarze, S.R.7
Friedl, A.8
-
84
-
-
33846527856
-
Independent prognostic significance of cell cycle regulator proteins p16(INK4a) and pRb in advanced-stage ovarian carcinoma including optimally debulked patients: A translational research subprotocol of a randomised study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group
-
Kommoss, S.; du Bois, A.; Ridder, R.; Trunk, M.J.; Schmidt, D.; Pfisterer, J.; Kommoss, F. Independent prognostic significance of cell cycle regulator proteins p16(INK4a) and pRb in advanced-stage ovarian carcinoma including optimally debulked patients: a translational research subprotocol of a randomised study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group. Br. J. Cancer 2007, 96, 306-313.
-
(2007)
Br. J. Cancer
, vol.96
, pp. 306-313
-
-
Kommoss, S.1
du Bois, A.2
Ridder, R.3
Trunk, M.J.4
Schmidt, D.5
Pfisterer, J.6
Kommoss, F.7
-
85
-
-
71849104873
-
P16ink4a inactivation mechanisms in non-small-cell lung cancer patients occupationally exposed to asbestos
-
Andujar, P.; Wang, J.; Descatha, A.; Galateau-Salle, F.; Abd-Alsamad, I.; Billon-Galland, M.A.; Blons, H.; Clin, B.; Danel, C.; Housset, B. et al. p16INK4A inactivation mechanisms in non-small-cell lung cancer patients occupationally exposed to asbestos. Lung Cancer 2010, 67, 23-30.
-
(2010)
Lung Cancer
, vol.67
, pp. 23-30
-
-
Andujar, P.1
Wang, J.2
Descatha, A.3
Galateau-Salle, F.4
Abd-Alsamad, I.5
Billon-Galland, M.A.6
Blons, H.7
Clin, B.8
Danel, C.9
Housset, B.10
-
86
-
-
0035754080
-
To cycle or not to cycle: A critical decision in cancer
-
Malumbres, M.; Barbacid, M. To cycle or not to cycle: a critical decision in cancer. Nat. Rev. Cancer 2001, 1, 222-231.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
87
-
-
1842484279
-
Repression of the human papillomavirus E6 gene initiates p53-dependent, Telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells
-
Horner, S.M.; DeFilippis, R.A.; Manuelidis, L.; DiMaio, D. Repression of the human papillomavirus E6 gene initiates p53-dependent, Telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. J. Virol. 2004, 78, 4063-4073.
-
(2004)
J. Virol
, vol.78
, pp. 4063-4073
-
-
Horner, S.M.1
Defilippis, R.A.2
Manuelidis, L.3
Dimaio, D.4
-
88
-
-
2342478606
-
Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells
-
Psyrri, A.; DeFilippis, R.A.; Edwards, A.P.; Yates, K.E.; Manuelidis, L.; DiMaio, D. Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells. Cancer Res. 2004, 64, 3079-3086.
-
(2004)
Cancer Res
, vol.64
, pp. 3079-3086
-
-
Psyrri, A.1
Defilippis, R.A.2
Edwards, A.P.3
Yates, K.E.4
Manuelidis, L.5
Dimaio, D.6
-
89
-
-
0037229178
-
Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells
-
DeFilippis, R.A.; Goodwin, E.C.; Wu, L.; DiMaio, D. Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells. J. Virol. 2003, 77, 1551-1563.
-
(2003)
J. Virol
, vol.77
, pp. 1551-1563
-
-
Defilippis, R.A.1
Goodwin, E.C.2
Wu, L.3
Dimaio, D.4
-
90
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook, T.F.; Martin, E.S.; Schlabach, M.R.; Leng, Y.; Liang, A.C.; Feng, B.; Zhao, J.J.; Roberts, T.M.; Mandel, G.; Hannon, G.J. et al. A genetic screen for candidate tumor suppressors identifies REST. Cell 2005, 121, 837-848.
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
Martin, E.S.2
Schlabach, M.R.3
Leng, Y.4
Liang, A.C.5
Feng, B.6
Zhao, J.J.7
Roberts, T.M.8
Mandel, G.9
Hannon, G.J.10
-
91
-
-
0034127794
-
A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: A potential role in derepression of neuroendocrine genes and a useful clinical marker
-
Coulson, J.M.; Edgson, J.L.; Woll, P.J.; Quinn, J.P. A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: A potential role in derepression of neuroendocrine genes and a useful clinical marker. Cancer Res. 2000, 60, 1840-1844.
-
(2000)
Cancer Res
, vol.60
, pp. 1840-1844
-
-
Coulson, J.M.1
Edgson, J.L.2
Woll, P.J.3
Quinn, J.P.4
-
92
-
-
41149119961
-
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation
-
Westbrook, T.F.; Hu, G.; Ang, X.L.; Mulligan, P.; Pavlova, N.N.; Liang, A.; Leng, Y.; Maehr, R.; Shi, Y.; Harper, J.W. et al. SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature 2008, 452, 370-374.
-
(2008)
Nature
, vol.452
, pp. 370-374
-
-
Westbrook, T.F.1
Hu, G.2
Ang, X.L.3
Mulligan, P.4
Pavlova, N.N.5
Liang, A.6
Leng, Y.7
Maehr, R.8
Shi, Y.9
Harper, J.W.10
-
93
-
-
84865120905
-
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
-
Kruidenier, L.; Chung, C.W.; Cheng, Z.; Liddle, J.; Che, K.; Joberty, G.; Bantscheff, M.; Bountra, C.; Bridges, A.; Diallo, H. et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 2012, 488, 404-408.
-
(2012)
Nature
, vol.488
, pp. 404-408
-
-
Kruidenier, L.1
Chung, C.W.2
Cheng, Z.3
Liddle, J.4
Che, K.5
Joberty, G.6
Bantscheff, M.7
Bountra, C.8
Bridges, A.9
Diallo, H.10
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