메뉴 건너뛰기




Volumn 9, Issue 7, 2014, Pages

Lineage-specific regulation of epigenetic modifier genes in human liver and brain

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; BMI1 PROTEIN; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 7; HISTONE H3; LYSINE; METHYLTRANSFERASE; PROTEIN CBX7; PROTEIN CBX8; PROTEIN EZH1; PROTEIN KAT2B; PROTEIN PRMT8; PROTEIN SETD7; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; TRANSCRIPTOME;

EID: 84904675460     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102035     Document Type: Article
Times cited : (27)

References (85)
  • 1
    • 77954696793 scopus 로고    scopus 로고
    • Markers of murine embryonic and neural stem cells, neurons and astrocytes: Reference points for developmental neurotoxicity testing
    • Kuegler PB, Zimmer B, Waldmann T, Baudis B, Ilmjarv S, et al. (2010) Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. ALTEX 27: 17-42.
    • (2010) ALTEX , vol.27 , pp. 17-42
    • Kuegler, P.B.1    Zimmer, B.2    Waldmann, T.3    Baudis, B.4    Ilmjarv, S.5
  • 2
    • 79251544228 scopus 로고    scopus 로고
    • Regulating the regulators: The post-translational code of class I HDAC1 and HDAC2
    • Segre CV, Chiocca S (2011) Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2. J Biomed Biotechnol 2011: 690848.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 690848
    • Segre, C.V.1    Chiocca, S.2
  • 3
    • 79956064734 scopus 로고    scopus 로고
    • Chromatin: Constructing the big picture
    • van Steensel B (2011) Chromatin: constructing the big picture. EMBO J 30: 1885-1895.
    • (2011) EMBO J , vol.30 , pp. 1885-1895
    • Van Steensel, B.1
  • 4
    • 69249220176 scopus 로고    scopus 로고
    • DNA methylation and methyl-CpG binding proteins: Developmental requirements and function
    • Bogdanovic O, Veenstra GJ (2009) DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma 118: 549-565.
    • (2009) Chromosoma , vol.118 , pp. 549-565
    • Bogdanovic, O.1    Veenstra, G.J.2
  • 5
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T (2007) Chromatin modifications and their function. Cell 128: 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 6
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • Clapier CR, Cairns BR (2009) The biology of chromatin remodeling complexes. Annu Rev Biochem 78: 273-304.
    • (2009) Annu Rev Biochem , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 7
    • 80054760131 scopus 로고    scopus 로고
    • K-acetylation and its enzymes: Overview and new developments
    • Aka JA, Kim GW, Yang XJ (2011) K-acetylation and its enzymes: overview and new developments. Handb Exp Pharmacol 206: 1-12.
    • (2011) Handb Exp Pharmacol , vol.206 , pp. 1-12
    • Aka, J.A.1    Kim, G.W.2    Yang, X.J.3
  • 8
    • 79954547992 scopus 로고    scopus 로고
    • The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity
    • Kappes F, Waldmann T, Mathew V, Yu J, Zhang L, et al. (2011) The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. Genes Dev 25: 673-678.
    • (2011) Genes Dev , vol.25 , pp. 673-678
    • Kappes, F.1    Waldmann, T.2    Mathew, V.3    Yu, J.4    Zhang, L.5
  • 9
    • 0035019466 scopus 로고    scopus 로고
    • Heterochromatin formation in mammalian cells: Interaction between histones and HP1 Proteins
    • DOI 10.1016/S1097-2765(01)00218-0
    • Nielsen AL, Oulad-Abdelghani M, Ortiz JA, Remboutsika E, Chambon P, et al. (2001) Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol Cell 7: 729-739. (Pubitemid 32436434)
    • (2001) Molecular Cell , vol.7 , Issue.4 , pp. 729-739
    • Nielsen, A.L.1    Oulad-Abdelghani, M.2    Ortiz, J.A.3    Remboutsika, E.4    Chambon, P.5    Losson, R.6
  • 10
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A (2007) Perceptions of epigenetics. Nature 447: 396-398.
    • (2007) Nature , vol.447 , pp. 396-398
    • Bird, A.1
  • 11
    • 34547856653 scopus 로고    scopus 로고
    • The human Mi-2/NuRD complex and gene regulation
    • DOI 10.1038/sj.onc.1210611, PII 1210611
    • Denslow SA, Wade PA (2007) The human Mi-2/NuRD complex and gene regulation. Oncogene 26: 5433-5438. (Pubitemid 47255925)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5433-5438
    • Denslow, S.A.1    Wade, P.A.2
  • 12
    • 1842733449 scopus 로고    scopus 로고
    • HP1 and the dynamics of heterochromatin maintenance
    • DOI 10.1038/nrm1355
    • Maison C, Almouzni G (2004) HP1 and the dynamics of heterochromatin maintenance. Nat Rev Mol Cell Biol 5: 296-304. (Pubitemid 38480610)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.4 , pp. 296-304
    • Maison, C.1    Almouzni, G.2
  • 15
    • 80052400888 scopus 로고    scopus 로고
    • Role of the nuclear lamina in genome organization and gene expression
    • Peric-Hupkes D, van Steensel B (2010) Role of the nuclear lamina in genome organization and gene expression. Cold Spring Harb Symp Quant Biol 75: 517-524.
    • (2010) Cold Spring Harb Symp Quant Biol , vol.75 , pp. 517-524
    • Peric-Hupkes, D.1    Van Steensel, B.2
  • 16
    • 65249173999 scopus 로고    scopus 로고
    • An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
    • Ho L, Jothi R, Ronan JL, Cui K, Zhao K, et al. (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci U S A 106: 5187-5191.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5187-5191
    • Ho, L.1    Jothi, R.2    Ronan, J.L.3    Cui, K.4    Zhao, K.5
  • 17
    • 0034762645 scopus 로고    scopus 로고
    • Pictures in molecular medicine contemplating Alzheimer's disease as cancer: A loss of cell-cycle control
    • DOI 10.1016/S1471-4914(01)02158-X, PII S147149140102158X
    • Herrup K, Yang Y (2001) Pictures in molecular medicine: contemplating Alzheimer's disease as cancer: a loss of cell-cycle control. Trends Mol Med 7: 527. (Pubitemid 33021684)
    • (2001) Trends in Molecular Medicine , vol.7 , Issue.11 , pp. 527
    • Herrup, K.1    Yang, Y.2
  • 19
    • 0037064078 scopus 로고    scopus 로고
    • Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line
    • DOI 10.1074/jbc.M205518200
    • Lotharius J, Barg S, Wiekop P, Lundberg C, Raymon HK, et al. (2002) Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. J Biol Chem 277: 38884-38894. (Pubitemid 35154753)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.41 , pp. 38884-38894
    • Lotharius, J.1    Barg, S.2    Wiekop, P.3    Lundberg, C.4    Raymon, H.K.5    Brundin, P.6
  • 20
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
    • Shilatifard A (2006) Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem 75: 243-269.
    • (2006) Annu Rev Biochem , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 21
    • 81055127451 scopus 로고    scopus 로고
    • Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line
    • Scholz D, Poltl D, Genewsky A, Weng M, Waldmann T, et al. (2011) Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line. J Neurochem 119: 957-971.
    • (2011) J Neurochem , vol.119 , pp. 957-971
    • Scholz, D.1    Poltl, D.2    Genewsky, A.3    Weng, M.4    Waldmann, T.5
  • 22
    • 84883464564 scopus 로고    scopus 로고
    • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
    • Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, et al. (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol 87: 1315-1530.
    • (2013) Arch Toxicol , vol.87 , pp. 1315-1530
    • Godoy, P.1    Hewitt, N.J.2    Albrecht, U.3    Andersen, M.E.4    Ansari, N.5
  • 23
    • 0033984235 scopus 로고    scopus 로고
    • The Ki-67 protein: From the known and the unknown
    • DOI 10.1002/(SICI)1097-4652(200003)182:3<311::AID
    • Scholzen T, Gerdes J (2000) The Ki-67 protein: from the known and the unknown. J Cell Physiol 182: 311-322. (Pubitemid 30054364)
    • (2000) Journal of Cellular Physiology , vol.182 , Issue.3 , pp. 311-322
    • Scholzen, T.1    Gerdes, J.2
  • 24
    • 67650999336 scopus 로고    scopus 로고
    • Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis
    • Godoy P, Hengstler JG, Ilkavets I, Meyer C, Bachmann A, et al. (2009) Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis. Hepatology 49: 2031-2043.
    • (2009) Hepatology , vol.49 , pp. 2031-2043
    • Godoy, P.1    Hengstler, J.G.2    Ilkavets, I.3    Meyer, C.4    Bachmann, A.5
  • 26
    • 0025410464 scopus 로고
    • Metastatic brain tumors-recent trends
    • Takakura K (1990) [Metastatic brain tumors-recent trends]. Gan To Kagaku Ryoho 17: 768-770.
    • (1990) Gan to Kagaku Ryoho , vol.17 , pp. 768-770
    • Takakura, K.1
  • 27
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome biology 3: RESEARCH0034.
    • (2002) Genome Biology , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 29
    • 79951678616 scopus 로고    scopus 로고
    • Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing
    • Zimmer B, Kuegler PB, Baudis B, Genewsky A, Tanavde V, et al. (2011) Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing. Cell death and differentiation 18: 383-395.
    • (2011) Cell Death and Differentiation , vol.18 , pp. 383-395
    • Zimmer, B.1    Kuegler, P.B.2    Baudis, B.3    Genewsky, A.4    Tanavde, V.5
  • 30
  • 31
    • 84896084435 scopus 로고    scopus 로고
    • Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation
    • Doi D, Samata B, Katsukawa M, Kikuchi T, Morizane A, et al. (2014) Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem Cell Reports 2: 337-350.
    • (2014) Stem Cell Reports , vol.2 , pp. 337-350
    • Doi, D.1    Samata, B.2    Katsukawa, M.3    Kikuchi, T.4    Morizane, A.5
  • 32
    • 84861100147 scopus 로고    scopus 로고
    • Spatial partitioning of the regulatory landscape of the X-inactivation centre
    • Nora EP, Lajoie BR, Schulz EG, Giorgetti L, Okamoto I, et al. (2012) Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature 485: 381-385.
    • (2012) Nature , vol.485 , pp. 381-385
    • Nora, E.P.1    Lajoie, B.R.2    Schulz, E.G.3    Giorgetti, L.4    Okamoto, I.5
  • 34
    • 34247508686 scopus 로고    scopus 로고
    • Cell cycle regulation in the postmitotic neuron: Oxymoron or new biology?
    • DOI 10.1038/nrn2124, PII NRN2124
    • Herrup K, Yang Y (2007) Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci 8: 368-378. (Pubitemid 46652467)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.5 , pp. 368-378
    • Herrup, K.1    Yang, Y.2
  • 35
    • 84873397441 scopus 로고    scopus 로고
    • Established and emerging variants of glioblastoma multiforme: Review of morphological and molecular features
    • Karsy M, Gelbman M, Shah P, Balumbu O, Moy F, et al. (2012) Established and emerging variants of glioblastoma multiforme: review of morphological and molecular features. Folia Neuropathol 50: 301-321.
    • (2012) Folia Neuropathol , vol.50 , pp. 301-321
    • Karsy, M.1    Gelbman, M.2    Shah, P.3    Balumbu, O.4    Moy, F.5
  • 36
    • 34548498378 scopus 로고    scopus 로고
    • Inhibition of TGF-beta induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase
    • DOI 10.1016/j.ejphar.2007.06.036, PII S001429990700725X
    • Dunkern TR, Feurstein D, Rossi GA, Sabatini F, Hatzelmann A (2007) Inhibition of TGF-beta induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase. Eur J Pharmacol 572: 12-22. (Pubitemid 47374681)
    • (2007) European Journal of Pharmacology , vol.572 , Issue.1 , pp. 12-22
    • Dunkern, T.R.1    Feurstein, D.2    Rossi, G.A.3    Sabatini, F.4    Hatzelmann, A.5
  • 39
    • 21844442345 scopus 로고    scopus 로고
    • Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway
    • DOI 10.1523/JNEUROSCI.1746-05.2005
    • Lotharius J, Falsig J, van Beek J, Payne S, Dringen R, et al. (2005) Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway. J Neurosci 25: 6329-6342. (Pubitemid 40962528)
    • (2005) Journal of Neuroscience , vol.25 , Issue.27 , pp. 6329-6342
    • Lotharius, J.1    Falsig, J.2    Van Beek, J.3    Payne, S.4    Dringen, R.5    Brundin, P.6    Leist, M.7
  • 40
    • 0034717183 scopus 로고    scopus 로고
    • Structure and function of a human TAF(II)250 double bromodomain module
    • DOI 10.1126/science.288.5470.1422
    • Jacobson RH, Ladurner AG, King DS, Tjian R (2000) Structure and function of a human TAFII250 double bromodomain module. Science 288: 1422-1425. (Pubitemid 30366328)
    • (2000) Science , vol.288 , Issue.5470 , pp. 1422-1425
    • Jacobson, R.H.1    Ladurner, A.G.2    King, D.S.3    Tjian, R.4
  • 41
    • 79955379993 scopus 로고    scopus 로고
    • Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures
    • Stiegler NV, Krug AK, Matt F, Leist M (2011) Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures. Toxicol Sci 121: 73-87.
    • (2011) Toxicol Sci , vol.121 , pp. 73-87
    • Stiegler, N.V.1    Krug, A.K.2    Matt, F.3    Leist, M.4
  • 42
    • 41549115095 scopus 로고    scopus 로고
    • The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription
    • DOI 10.1016/j.molcel.2008.01.018, PII S1097276508001573
    • LeRoy G, Rickards B, Flint SJ (2008) The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Mol Cell 30: 51-60. (Pubitemid 351470152)
    • (2008) Molecular Cell , vol.30 , Issue.1 , pp. 51-60
    • LeRoy, G.1    Rickards, B.2    Flint, S.J.3
  • 43
    • 24344460521 scopus 로고    scopus 로고
    • 14-3-3 proteins-an update
    • Mhawech P (2005) 14-3-3 proteins-an update. Cell Res 15: 228-236.
    • (2005) Cell Res , vol.15 , pp. 228-236
    • Mhawech, P.1
  • 44
    • 78651162036 scopus 로고
    • Acetylation and Methylation of Histones and Their Possible Role in the Regulation of Rna Synthesis
    • Allfrey VG, Faulkner R, Mirsky AE (1964) Acetylation and Methylation of Histones and Their Possible Role in the Regulation of Rna Synthesis. Proc Natl Acad Sci U S A 51: 786-794.
    • (1964) Proc Natl Acad Sci U S A , vol.51 , pp. 786-794
    • Allfrey, V.G.1    Faulkner, R.2    Mirsky, A.E.3
  • 46
    • 80053924587 scopus 로고    scopus 로고
    • H3K9 histone acetylation predicts pluripotency and reprogramming capacity of ES cells
    • Hezroni H, Tzchori I, Davidi A, Mattout A, Biran A, et al. (2011) H3K9 histone acetylation predicts pluripotency and reprogramming capacity of ES cells. Nucleus 2: 300-309.
    • (2011) Nucleus , vol.2 , pp. 300-309
    • Hezroni, H.1    Tzchori, I.2    Davidi, A.3    Mattout, A.4    Biran, A.5
  • 47
    • 0003073157 scopus 로고    scopus 로고
    • Identification of neurogenin, a vertebrate neuronal determination gene
    • DOI 10.1016/S0092-8674(00)81321-5
    • Ma Q, Kintner C, Anderson DJ (1996) Identification of neurogenin, a vertebrate neuronal determination gene. Cell 87: 43-52. (Pubitemid 26337389)
    • (1996) Cell , vol.87 , Issue.1 , pp. 43-52
    • Ma, Q.1    Kintner, C.2    Anderson, D.J.3
  • 48
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage FH (2000) Mammalian neural stem cells. Science 287: 1433-1438.
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 49
    • 0035797485 scopus 로고    scopus 로고
    • The role of tangential migration in the establishment of mammalian cortex
    • DOI 10.1016/S0896-6273(01)00370-1
    • Maricich SM, Gilmore EC, Herrup K (2001) The role of tangential migration in the establishment of mammalian cortex. Neuron 31: 175-178. (Pubitemid 32762973)
    • (2001) Neuron , vol.31 , Issue.2 , pp. 175-178
    • Maricich, S.M.1    Gilmore, E.C.2    Herrup, K.3
  • 50
    • 84896730248 scopus 로고    scopus 로고
    • Human stem cell models of neurodegeneration: A novel approach to study mechanisms of disease development
    • Hargus G, Ehrlich M, Hallmann AL, Kuhlmann T (2014) Human stem cell models of neurodegeneration: a novel approach to study mechanisms of disease development. Acta Neuropathol 127: 151-173.
    • (2014) Acta Neuropathol , vol.127 , pp. 151-173
    • Hargus, G.1    Ehrlich, M.2    Hallmann, A.L.3    Kuhlmann, T.4
  • 51
    • 0042810707 scopus 로고    scopus 로고
    • The CDY-related gene family: Coordinated evolution in copy number, expression profile and protein sequence
    • DOI 10.1093/hmg/ddg185
    • Dorus S, Gilbert SL, Forster ML, Barndt RJ, Lahn BT (2003) The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. Hum Mol Genet 12: 1643-1650. (Pubitemid 36896657)
    • (2003) Human Molecular Genetics , vol.12 , Issue.14 , pp. 1643-1650
    • Dorus, S.1    Gilbert, S.L.2    Forster, M.L.3    Barndt, R.J.4    Lahn, B.T.5
  • 52
    • 32544459388 scopus 로고    scopus 로고
    • Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models
    • DOI 10.1523/JNEUROSCI.3707-05.2006
    • Yang Y, Varvel NH, Lamb BT, Herrup K (2006) Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models. J Neurosci 26: 775-784. (Pubitemid 43237070)
    • (2006) Journal of Neuroscience , vol.26 , Issue.3 , pp. 775-784
    • Yang, Y.1    Varvel, N.H.2    Lamb, B.T.3    Herrup, K.4
  • 53
    • 20044367108 scopus 로고    scopus 로고
    • Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
    • DOI 10.1523/JNEUROSCI.4637-04.2005
    • Andorfer C, Acker CM, Kress Y, Hof PR, Duff K, et al. (2005) Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci 25: 5446-5454. (Pubitemid 40770926)
    • (2005) Journal of Neuroscience , vol.25 , Issue.22 , pp. 5446-5454
    • Andorfer, C.1    Acker, C.M.2    Kress, Y.3    Hof, P.R.4    Duff, K.5    Davies, P.6
  • 54
    • 0036463405 scopus 로고    scopus 로고
    • A matter of life and death
    • DOI 10.1016/S1535-6108(02)00024-7
    • Green DR, Evan GI (2002) A matter of life and death. Cancer Cell 1: 19-30. (Pubitemid 41039172)
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 19-30
    • Green, D.R.1    Evan, G.I.2
  • 55
    • 84874546182 scopus 로고    scopus 로고
    • Epigenetic mechanisms in the development and maintenance of dopaminergic neurons
    • van Heesbeen HJ, Mesman S, Veenvliet JV, Smidt MP (2013) Epigenetic mechanisms in the development and maintenance of dopaminergic neurons. Development 140: 1159-1169.
    • (2013) Development , vol.140 , pp. 1159-1169
    • Van Heesbeen, H.J.1    Mesman, S.2    Veenvliet, J.V.3    Smidt, M.P.4
  • 56
    • 84862639469 scopus 로고    scopus 로고
    • DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina
    • Zullo JM, Demarco IA, Pique-Regi R, Gaffney DJ, Epstein CB, et al. (2012) DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell 149: 1474-1487.
    • (2012) Cell , vol.149 , pp. 1474-1487
    • Zullo, J.M.1    Demarco, I.A.2    Pique-Regi, R.3    Gaffney, D.J.4    Epstein, C.B.5
  • 57
    • 84888133742 scopus 로고    scopus 로고
    • Epigenetic changes in the progression of Alzheimer's disease
    • Bradley-Whitman MA, Lovell MA (2013) Epigenetic changes in the progression of Alzheimer's disease. Mech Ageing Dev 134: 486-495.
    • (2013) Mech Ageing Dev , vol.134 , pp. 486-495
    • Bradley-Whitman, M.A.1    Lovell, M.A.2
  • 58
    • 84877930649 scopus 로고    scopus 로고
    • Targeting histone modifications-epigenetics in cancer
    • Waldmann T, Schneider R (2013) Targeting histone modifications- epigenetics in cancer. Curr Opin Cell Biol 25: 184-189.
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 184-189
    • Waldmann, T.1    Schneider, R.2
  • 59
    • 0036008097 scopus 로고    scopus 로고
    • Deacetylase enzymes: Biological functions and the use of small-molecule inhibitors
    • DOI 10.1016/S1074-5521(02)00092-3, PII S1074552102000923
    • Grozinger CM, Schreiber SL (2002) Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. Chem Biol 9: 3-16. (Pubitemid 34155860)
    • (2002) Chemistry and Biology , vol.9 , Issue.1 , pp. 3-16
    • Grozinger, C.M.1    Schreiber, S.L.2
  • 61
    • 34347381069 scopus 로고    scopus 로고
    • Irreversible cell-cycle transitions are due to systems-level feedback
    • DOI 10.1038/ncb0707-724, PII NCB0707-724
    • Novak B, Tyson JJ, Gyorffy B, Csikasz-Nagy A (2007) Irreversible cell-cycle transitions are due to systems-level feedback. Nat Cell Biol 9: 724-728. (Pubitemid 47019454)
    • (2007) Nature Cell Biology , vol.9 , Issue.7 , pp. 724-728
    • Novak, B.1    Tyson, J.J.2    Gyorffy, B.3    Csikasz-Nagy, A.4
  • 63
    • 34250352746 scopus 로고    scopus 로고
    • 4 methyltransferase complex
    • DOI 10.1074/jbc.M609809200
    • Lee JH, Tate CM, You JS, Skalnik DG (2007) Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex. J Biol Chem 282: 13419-13428. (Pubitemid 47100496)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.18 , pp. 13419-13428
    • Lee, J.-H.1    Tate, C.M.2    You, J.-S.3    Skalnik, D.G.4
  • 64
    • 84864585700 scopus 로고    scopus 로고
    • Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity
    • Endoh M, Endo TA, Endoh T, Isono K, Sharif J, et al. (2012) Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet 8: e1002774.
    • (2012) PLoS Genet , vol.8
    • Endoh, M.1    Endo, T.A.2    Endoh, T.3    Isono, K.4    Sharif, J.5
  • 65
    • 9444244427 scopus 로고    scopus 로고
    • Chromatin compaction by a polycomb group protein complex
    • DOI 10.1126/science.1100576
    • Francis NJ, Kingston RE, Woodcock CL (2004) Chromatin compaction by a polycomb group protein complex. Science 306: 1574-1577. (Pubitemid 39564957)
    • (2004) Science , vol.306 , Issue.5701 , pp. 1574-1577
    • Francis, N.J.1    Kingston, R.E.2    Woodcock, C.L.3
  • 66
    • 79959537139 scopus 로고    scopus 로고
    • Continued stabilization of the nuclear higher-order structure of post-mitotic neurons in vivo
    • Alva-Medina J, Maya-Mendoza A, Dent MA, Aranda-Anzaldo A (2011) Continued stabilization of the nuclear higher-order structure of post-mitotic neurons in vivo. PLoS One 6: e21360.
    • (2011) PLoS One , vol.6
    • Alva-Medina, J.1    Maya-Mendoza, A.2    Dent, M.A.3    Aranda-Anzaldo, A.4
  • 67
    • 79955105138 scopus 로고    scopus 로고
    • The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion
    • Selige J, Hatzelmann A, Dunkern T (2011) The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion. J Cell Physiol 226: 1970-1980.
    • (2011) J Cell Physiol , vol.226 , pp. 1970-1980
    • Selige, J.1    Hatzelmann, A.2    Dunkern, T.3
  • 68
    • 84886240487 scopus 로고    scopus 로고
    • Epigenetics components of aging in the central nervous system
    • Zhao YQ, Jordan IK, Lunyak VV (2013) Epigenetics components of aging in the central nervous system. Neurotherapeutics 10: 647-663.
    • (2013) Neurotherapeutics , vol.10 , pp. 647-663
    • Zhao, Y.Q.1    Jordan, I.K.2    Lunyak, V.V.3
  • 70
    • 3042547731 scopus 로고    scopus 로고
    • Combining intensity, edge and shape information for 2D and 3D segmentation of cell nuclei in tissue sections
    • DOI 10.1111/j.0022-2720.2004.01338.x
    • Wahlby C, Sintorn IM, Erlandsson F, Borgefors G, Bengtsson E (2004) Combining intensity, edge and shape information for 2D and 3D segmentation of cell nuclei in tissue sections. J Microsc 215: 67-76. (Pubitemid 38845127)
    • (2004) Journal of Microscopy , vol.215 , Issue.1 , pp. 67-76
    • Wahlby, C.1    Sintorn, I.-M.2    Erlandsson, F.3    Borgefors, G.4    Bengtsson, E.5
  • 72
    • 84855610352 scopus 로고    scopus 로고
    • The DNA replication stress hypothesis of Alzheimer's disease
    • Yurov YB, Vorsanova SG, Iourov IY (2011) The DNA replication stress hypothesis of Alzheimer's disease. ScientificWorldJournal 11: 2602-2612.
    • (2011) ScientificWorldJournal , vol.11 , pp. 2602-2612
    • Yurov, Y.B.1    Vorsanova, S.G.2    Iourov, I.Y.3
  • 73
    • 33947289969 scopus 로고    scopus 로고
    • Cell division in the CNS: Protective response or lethal event in post-mitotic neurons?
    • DOI 10.1016/j.bbadis.2006.10.002, PII S0925443906001992
    • Yang Y, Herrup K (2007) Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta 1772: 457-466. (Pubitemid 46420409)
    • (2007) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1772 , Issue.4 , pp. 457-466
    • Yang, Y.1    Herrup, K.2
  • 74
    • 84878406298 scopus 로고    scopus 로고
    • Epigenetic mechanisms of gene expression regulation in neurological diseases
    • Gos M (2013) Epigenetic mechanisms of gene expression regulation in neurological diseases. Acta Neurobiol Exp (Wars) 73: 19-37.
    • (2013) Acta Neurobiol Exp (Wars) , vol.73 , pp. 19-37
    • Gos, M.1
  • 75
    • 84864700183 scopus 로고    scopus 로고
    • Epigenetic mechanisms in neurological disease
    • Jakovcevski M, Akbarian S (2012) Epigenetic mechanisms in neurological disease. Nat Med 18: 1194-1204.
    • (2012) Nat Med , vol.18 , pp. 1194-1204
    • Jakovcevski, M.1    Akbarian, S.2
  • 77
    • 0037305849 scopus 로고    scopus 로고
    • Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system
    • DOI 10.1128/MCB.23.3.1044-1053.2003
    • MacPherson D, Sage J, Crowley D, Trumpp A, Bronson RT, et al. (2003) Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol Cell Biol 23: 1044-1053. (Pubitemid 36133520)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.3 , pp. 1044-1053
    • MacPherson, D.1    Sage, J.2    Crowley, D.3    Trumpp, A.4    Bronson, R.T.5    Jacks, T.6
  • 78
    • 77957680712 scopus 로고    scopus 로고
    • Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
    • Pereira JD, Sansom SN, Smith J, Dobenecker MW, Tarakhovsky A, et al. (2010) Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci U S A 107: 15957-15962.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15957-15962
    • Pereira, J.D.1    Sansom, S.N.2    Smith, J.3    Dobenecker, M.W.4    Tarakhovsky, A.5
  • 79
    • 55949132133 scopus 로고    scopus 로고
    • Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms
    • Margueron R, Li G, Sarma K, Blais A, Zavadil J, et al. (2008) Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. Mol Cell 32: 503-518.
    • (2008) Mol Cell , vol.32 , pp. 503-518
    • Margueron, R.1    Li, G.2    Sarma, K.3    Blais, A.4    Zavadil, J.5
  • 80
    • 33749260519 scopus 로고    scopus 로고
    • Nuclear ADP-ribosylation reactions in mammalian cells: Where are we today and where are we going?
    • DOI 10.1128/MMBR.00040-05
    • Hassa PO, Haenni SS, Elser M, Hottiger MO (2006) Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? Microbiol Mol Biol Rev 70: 789-829. (Pubitemid 44484693)
    • (2006) Microbiology and Molecular Biology Reviews , vol.70 , Issue.3 , pp. 789-829
    • Hassa, P.O.1    Haenni, S.S.2    Elser, M.3    Hottiger, M.O.4
  • 81
    • 0016221697 scopus 로고
    • Chromatin structure: A repeating unit of histones and DNA
    • Kornberg RD (1974) Chromatin structure: a repeating unit of histones and DNA. Science 184: 868-871.
    • (1974) Science , vol.184 , pp. 868-871
    • Kornberg, R.D.1
  • 82
    • 18844413266 scopus 로고    scopus 로고
    • Acetylation in histone H3 globular domain regulates gene expression in yeast
    • DOI 10.1016/j.cell.2005.03.011, PII S0092867405002837
    • Xu F, Zhang K, Grunstein M (2005) Acetylation in histone H3 globular domain regulates gene expression in yeast. Cell 121: 375-385. (Pubitemid 40692298)
    • (2005) Cell , vol.121 , Issue.3 , pp. 375-385
    • Xu, F.1    Zhang, K.2    Grunstein, M.3
  • 83
    • 34548434716 scopus 로고    scopus 로고
    • Whole-Genome Analysis of Histone H3 Lysine 4 and Lysine 27 Methylation in Human Embryonic Stem Cells
    • DOI 10.1016/j.stem.2007.08.003, PII S1934590907001221
    • Pan G, Tian S, Nie J, Yang C, Ruotti V, et al. (2007) Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1: 299-312. (Pubitemid 47355329)
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 299-312
    • Pan, G.1    Tian, S.2    Nie, J.3    Yang, C.4    Ruotti, V.5    Wei, H.6    Jonsdottir, G.A.7    Stewart, R.8    Thomson, J.A.9
  • 85
    • 79952539053 scopus 로고    scopus 로고
    • ATP-dependent chromatin remodeling: Genetics, genomics and mechanisms
    • Hargreaves DC, Crabtree GR (2011) ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res 21: 396-420.
    • (2011) Cell Res , vol.21 , pp. 396-420
    • Hargreaves, D.C.1    Crabtree, G.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.