Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways

Journal of Clinical Investigation

Volumn 124, Issue 1, 2014, Pages 367-384

  Onodera, Yasuhito ^a,b   Nam, Jin Min ^c   Bissell, Mina J ^a  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b Department of Molecular Biology ^*  (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE KINASE; ANTIPORTER; BETA1 INTEGRIN; CYCLIC AMP; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCOSE; GLUCOSE TRANSPORTER 3; HEXOSAMINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; N ACETYLGLUCOSAMINE; O LINKED N ACETYLGLUCOSAMINE; PROTEIN KINASE B; PYRUVATE KINASE; RAP1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; BREAST CELL; CANCER CELL; CARCINOGENESIS; CELL POLARITY; CELL TRANSPORT; CHEMICAL MODIFICATION; CONTROLLED STUDY; EPITHELIUM; EXPERIMENTAL MODEL; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUGAR TRANSPORT; THREE DIMENSIONAL IMAGING;

EID: 84892909254     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI63146     Document Type: Article

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