Discovery of novel steroidal pyran-oxindole hybrids as cytotoxic agents

Steroids

Volumn 88, Issue , 2014, Pages 44-52

  Yu, Bin ^a   Qi, Ping Ping ^a   Shi, Xiao Jing ^a   Shan, Li Hong ^a   Yu, De Quan ^a   Liu, Hong Min ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle arrest; Cytotoxicity; Pyran oxindole hybrids

Indexed keywords

3BETA ACETYL DEHYDROEPIANDROSTERONE; ANTINEOPLASTIC AGENT; FLUOROURACIL; STEROIDAL ALPHA, ALPHA DICYANOALKENE; STEROIDAL PYRAN OXINDOLE HYBRID; UNCLASSIFIED DRUG; INDOLE DERIVATIVE; OXINDOLE; PYRAN DERIVATIVE; STEROID;

ALDOL REACTION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL BOND; COLUMN CHROMATOGRAPHY; DRUG SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MCF 7 CELL LINE; PROTON NUCLEAR MAGNETIC RESONANCE; STEROIDOGENESIS; THIN LAYER CHROMATOGRAPHY; CELL CYCLE; CHEMISTRY; DOSE RESPONSE; DRUG DESIGN; DRUG EFFECTS; TIME; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HUMANS; INDOLES; PYRANS; STEROIDS; TIME FACTORS;

EID: 84904582012     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2014.05.022     Document Type: Article

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