Inhibition of brain ischemia-caused Notch activation in microglia may contribute to isoflurane postconditioning-induced neuroprotection in male rats

CNS and Neurological Disorders - Drug Targets

Volumn 13, Issue 4, 2014, Pages 718-732

  Yin, Jinbo ^a,b   Li, Hong ^a,b   Feng, Chenzhuo ^a   Zuo, Zhiyi ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Focal brain ischemia; Isoflurane; Microglia; Notch; Postconditioning

Indexed keywords

CASPASE 3; CYTOKINE; ISOFLURANE; LIPOPOLYSACCHARIDE; NOTCH RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CASP3 PROTEIN, RAT; CD11B ANTIGEN; GLUCOSE; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BODY TEMPERATURE; BRAIN INJURY; BRAIN ISCHEMIA; CELL DENSITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART RATE; IMMUNOFLUORESCENCE; ISCHEMIC POSTCONDITIONING; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXYGEN SATURATION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; BRAIN; CELL HYPOXIA; CELL LINE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIGENS, CD11B; BRAIN; BRAIN ISCHEMIA; CASPASE 3; CELL HYPOXIA; CELL LINE; CYTOKINES; DISEASE MODELS, ANIMAL; GLUCOSE; INFARCTION, MIDDLE CEREBRAL ARTERY; ISOFLURANE; LIPOPOLYSACCHARIDES; MALE; MICE; MICROGLIA; NEUROPROTECTIVE AGENTS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84904461027     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527313666140618110837     Document Type: Article

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