Perioperative stroke in noncardiac, nonneurosurgical surgery

Anesthesiology

Volumn 115, Issue 4, 2011, Pages 879-890

  Ng, Julie L W ^a   Chan, Matthew T V ^b   Gelb, Adrian W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; LOW MOLECULAR WEIGHT HEPARIN; TUMOR NECROSIS FACTOR ALPHA; UREA; WARFARIN;

AGE; ANTICOAGULANT THERAPY; ATHEROGENESIS; BLOOD PRESSURE REGULATION; BODY MASS; BRADYCARDIA; BRAIN EMBOLISM; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CAROTID ARTERY; CAROTID ARTERY STENTING; CEREBROVASCULAR DISEASE; CESAREAN SECTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; DELAYED DIAGNOSIS; DIABETES MELLITUS; DISEASE PREDISPOSITION; DRUG INDICATION; DRUG USE; ELECTIVE SURGERY; ENDARTERECTOMY; GENERAL ANESTHESIA; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEMICOLECTOMY; HIGH RISK POPULATION; HIP ARTHROPLASTY; HIP FRACTURE; HIP SURGERY; HUMAN; HYPERTENSION; HYPERURICEMIA; HYPOTENSION; IMMUNE RESPONSE; INFLAMMATION; KNEE ARTHROPLASTY; LOW DRUG DOSE; LUNG RESECTION; METABOLIC DISORDER; MORBIDITY; NEOPLASM; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCLUSIVE CEREBROVASCULAR DISEASE; ORTHOPEDIC SURGERY; PERIOPERATIVE COMPLICATION; PERIPHERAL VASCULAR DISEASE; POSTOPERATIVE PERIOD; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; REGIONAL ANESTHESIA; REVASCULARIZATION; REVIEW; RISK REDUCTION; SENESCENCE; SMOKING; STROKE; SURGICAL MORTALITY; SURGICAL RISK; THORAX SURGERY; THROMBOEMBOLISM; TRANSIENT ISCHEMIC ATTACK; UREA BLOOD LEVEL; VALVULAR HEART DISEASE; VASCULAR DISEASE; VASCULAR SURGERY;

EID: 80053344878     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31822e9499     Document Type: Review

References (116)

1. Wong GY, Warner DO, Schroeder DR, Offord KP, Warner MA, Maxson PM, Whisnant JP: Risk of surgery and anesthesia for ischemic stroke. ANESTHESIOLOGY 2000; 92:425-32 (Pubitemid 30078340)
2. Debette S, Markus HS: The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: Systematic review and meta-analysis. BMJ 2010; 341: c3666
3. Barber PA, Hach S, Tippett LJ, Ross L, Merry AF, Milsom P: Cerebral ischemic lesions on diffusion-weighted imaging are associated with neurocognitive decline after cardiac surgery. Stroke 2008; 39:1427-33
4. Knapp RB, Topkins MJ, Artusio JF, Jr: The cerebrovascular accident and coronary occlusion in anesthesia. JAMA 1962; 182:332-4
5. Cooperman M, Pflug B, Martin EW, Jr., Evans WE: Cardiovascular risk factors in patients with peripheral vascular disease. Surgery 1978; 84:505-9 (Pubitemid 9033946)
6. Turnipseed WD, Berkoff HA, Belzer FO: Postoperative stroke in cardiac and peripheral vascular disease. Ann Surg 1980; 192:365-8 (Pubitemid 10048283)
7. Hart R, Hindman B: Mechanisms of perioperative cerebral infarction. Stroke 1982; 13:766-73 (Pubitemid 13251487)
8. Larsen SF, Zaric D, Boysen G: Postoperative cerebrovascular accidents in general surgery. Acta Anaesthesiol Scand 1988; 32:698-701 (Pubitemid 19002364)
9. Landercasper J, Merz BJ, Cogbill TH, Strutt PJ, Cochrane RH, Olson RA, Hutter RD: Perioperative stroke risk in 173 consecutive patients with a past history of stroke. Arch Surg 1990; 125:986-9 (Pubitemid 20249334)
10. Parikh S, Cohen JR: Perioperative stroke after general surgical procedures. N Y State J Med 1993; 93:162-5 (Pubitemid 23127755)
11. Limburg M, Wijdicks EF, Li H: Ischemic stroke after surgical procedures: Clinical features, neuroimaging, and risk factors. Neurology 1998; 50:895-901 (Pubitemid 28212812)
12. Kikura M, Takada T, Sato S: Preexisting morbidity as an independent risk factor for perioperative acute thromboembolism syndrome. Arch Surg 2005; 140:1210-7 (Pubitemid 41815907)
13. Parvizi J, Mui A, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH: Total joint arthroplasty: When do fatal or near-fatal complications occur? J Bone Joint Surg Am 2007; 89:27-32 (Pubitemid 46059141)
14. Kikura M, Oikawa F, Yamamoto K, Iwamoto T, Tanaka KA, Sato S, Landesberg G: Myocardial infarction and cerebrovascular accident following non-cardiac surgery: Differences in postoperative temporal distribution and risk factors. J Thromb Haemost 2008; 6:742-8 (Pubitemid 351524532)
15. Popa AS, Rabinstein AA, Huddleston PM, Larson DR, Gullerud RE, Huddleston JM: Predictors of ischemic stroke after hip operation: A population-based study. J Hosp Med 2009; 4:298-303
16. Bateman BT, Schumacher HC, Wang S, Shaefi S, Berman MF: Perioperative acute ischemic stroke in noncardiac and nonvascular surgery: Incidence, risk factors, and outcomes. ANESTHESIOLOGY 2009; 110:231-8
17. Huang CJ, Fan YC, Tsai PS: Differential impacts of modes of anaesthesia on the risk of stroke among preeclamptic women who undergo Caesarean delivery: A populationbased study. Br J Anaesth 2010; 105:818-26
18. Kokotailo RA, Hill MD: Coding of stroke and stroke risk factors using international classification of diseases, revisions 9 and 10. Stroke 2005; 36:1776-81 (Pubitemid 41098778)
19. El-Saed A, Kuller LH, Newman AB, Lopez O, Costantino J, McTigue K, Cushman M, Kronmal R: Geographic variations in stroke incidence and mortality among older populations in four US communities. Stroke 2006; 37:1975-9 (Pubitemid 44309889)
20. Elkind MS: Inflammatory mechanisms of stroke. Stroke 2010; 41:S3-8
21. McColl BW, Allan SM, Rothwell NJ: Systemic infection, inflammation and acute ischemic stroke. Neuroscience 2009; 158:1049-61
22. McColl BW, Rothwell NJ, Allan SM: Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1 and neutrophil-dependent mechanisms. J Neurosci 2007; 27:4403-12 (Pubitemid 46640725)
23. Utagawa A, Truettner JS, Dietrich WD, Bramlett HM: Systemic inflammation exacerbates behavioral and histopathologic consequences of isolated traumatic brain injury in rats. Exp Neurol 2008; 211:283-91
24. Smith CJ, Emsley HC, Vail A, Georgiou RF, Rothwell NJ, Tyrrell PJ, Hopkins SJ: Variability of the systemic acute phase response after ischemic stroke. J Neurol Sci 2006; 251:77-81 (Pubitemid 44792143)
25. Zeller JA, Lenz A, Eschenfelder CC, Zunker P, Deuschl G: Platelet-leukocyte interaction and platelet activation in acute stroke with and without preceding infection. Arterioscler Thromb Vasc Biol 2005; 25:1519-23 (Pubitemid 40923378)
26. Palasik W, Fiszer U, Lechowicz W, Czartoryska B, Krzesiewicz M, Lugowska A: Assessment of relations between clinical outcome of ischemic stroke and activity of inflammatory processes in the acute phase based on examination of selected parameters. Eur Neurol 2005; 53:188-93 (Pubitemid 41404747)
27. Clayton TC, Thompson M, Meade TW: Recent respiratory infection and risk of cardiovascular disease: Case-control study through a general practice database. Eur Heart J 2008; 29:96-103
28. Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P: Risk of myocardial infarction and stroke after acute infection or vaccination. N Engl J Med 2004; 351: 2611-8 (Pubitemid 39628582)
29. Grau AJ, Buggle F, Heindl S, Steichen-Wiehn C, Banerjee T, Maiwald M, Rohlfs M, Suhr H, Fiehn W, Becher H, Werner H: Recent infection as a risk factor for cerebrovascular ischemia. Stroke 1995; 26:373-9
30. Bastian D, Tamburstuen MV, Lyngstadaas SP, Reikerås O: Systemic and local cytokine kinetics after total hip replacement surgery. Eur Surg Res 2008; 41:334-40
31. Riché F, Dosquet C, Panis Y, Valleur P, Laisne MJ, Briard C, Wautier JL: Levels of portal and systemic blood cytokines after colectomy in patients with carcinoma or Crohn's disease. J Am Coll Surg 1995; 180:718-24
32. Smith CJ, Emsley HC, Gavin CM, Georgiou RF, Vail A, Barberan EM, del Zoppo GJ, Hallenbeck JM, Rothwell NJ, Hopkins SJ, Tyrrell PJ: Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome. BMC Neurol 2004; 4:2
33. Rallidis LS, Vikelis M, Panagiotakos DB, Rizos I, Zolindaki MG, Kaliva K, Kremastinos DT: Inflammatory markers and in-hospital mortality in acute ischaemic stroke. Atherosclerosis 2006; 189:193-7 (Pubitemid 44441281)
34. Bamford J, Sandercock P, Dennis M, Burn J, Warlow C: Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991; 337:1521-6
35. Adams HP, Jr., Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24:35-41 (Pubitemid 23014379)
36. Mohr JP: Distal field infarction. Neurology 1969; 19:279
37. Momjian-Mayor I, Baron JC: The pathophysiology of watershed infarction in internal carotid artery disease: Review of cerebral perfusion studies. Stroke 2005; 36:567-77 (Pubitemid 40344158)
38. Caplan LR, Hennerici M: Impaired clearance of emboli (washout) is an important link between hypoperfusion, embolism, and ischemic stroke. Arch Neurol 1998; 55: 1475-82 (Pubitemid 28525511)
39. Likosky DS, Marrin CA, Caplan LR, Baribeau YR, Morton JR, Weintraub RM, Hartman GS, Hernandez F, Jr., Braff SP, Charlesworth DC, Malenka DJ, Ross CS, O'Connor GT, Northern New England Cardiovascular Disease Study Group: Determination of etiologic mechanisms of strokes secondary to coronary artery bypass graft surgery. Stroke 2003; 34:2830-4 (Pubitemid 37517751)
40. Abrams J: Role of endothelial dysfunction in coronary artery disease. Am J Cardiol 1997; 79:2-9 (Pubitemid 27305155)
41. Devereaux PJ, Chan MTV, Eikelboom J: Major vascular complications in patients undergoing non-cardiac surgery: Magnitude of the problem, risk prediction, surveillance, and prevention. Evidence based Cardiology, 3rd edition. Edited by Yusuf S, Cairns JA, Camm AJ, Fallen EL, Gersh BJ. West Sussex, UK; Wiley-Blackwell, 2010, pp 47-62
42. Myles PS, Chan MTV, Leslie K, Peyton P, Paech M, Forbes A: Effect of nitrous oxide on plasma homocysteine and folate in patients undergoing major surgery. Br J Anaesth 2008; 100:780-6 (Pubitemid 351774329)
43. Myles PS, Chan MTV, Kaye DM, McIlroy DR, Lau CW, Symons JA, Chen SH: Effect of nitrous oxide anesthesia on plasma homocysteine and endothelial dysfunction. ANESTHESIOLOGY 2008; 109: 657-63
44. Collins GJ, Jr., Barber JA, Zajtchuk R, Vanek D, Malogne LA: The effects of operative stress on the coagulation profile. Am J Surg 1977; 133:612-6 (Pubitemid 8105332)
45. Kluft C, Cooper P, Jie AF, Lowe GD, Forbes CD, Blamey SL, van de Putte LB: Evaluation of euglobulin methods for the study of blood fibrinolytic activity: Results for patients with rheumatoid arthritis and in the postoperative period. Haemostasis 1985; 15:144-50 (Pubitemid 15035502)
46. Dixon B, Santamaria J, Campbell D: Coagulation activation and organ dysfunction following cardiac surgery. Chest 2005; 128:229-36 (Pubitemid 40994478)
47. Hinterhuber G, Bohler K, Kittler H, Quehenberger P: Extended monitoring of hemostatic activation after varicose vein surgery under general anesthesia. Dermatol Surg 2006; 32:632-9 (Pubitemid 43742524)
48. Vagnerova K, Koerner IP, Hurn PD: Gender and the injured brain. Anesth Analg 2008; 107:201-14
49. Selim M: Perioperative stroke. N Engl J Med 2007; 356: 706-13
50. Ropper AH, Wechsler LR, Wilson LS: Carotid bruit and the risk of stroke in elective surgery. N Engl J Med 1982; 307:1388-90 (Pubitemid 13233016)
51. Naylor AR, Mehta Z, Rothwell PM, Bell PR: Carotid artery disease and stroke during coronary artery bypass: A critical review of the literature. Eur J Vasc Endovasc Surg 2002; 23:283-94 (Pubitemid 41079436)
52. Li Y, Walicki D, Mathiesen C, Jenny D, Li Q, Isayev Y, Reed JF, 3rd, Castaldo JE: Strokes after cardiac surgery and relationship to carotid stenosis. Arch Neurol 2009; 66:1091-6
53. Chimowitz MI, Lynn MJ, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel MR, Levine SR, Chaturvedi S, Kasner SE, Benesch CG, Sila CA, Jovin TG, Romano JG: Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 2005; 352:1305-16
54. Thompson SK, Southern DA, McKinnon JG, Dort JC, Ghali WA: Incidence of perioperative stroke after neck dissection for head and neck cancer: A regional outcome analysis. Ann Surg 2004; 239:428-31 (Pubitemid 38229074)
55. Rechtweg J, Wax MK, Shah R, Granke K, Jarmuz T: Neck dissection with simultaneous carotid endarterectomy. Laryngoscope 1998; 108:1150-3 (Pubitemid 28373476)
56. Nosan DK, Gomez CR, Maves MD: Perioperative stroke in patients undergoing head and neck surgery. Ann Otol Rhinol Laryngol 1993; 102:717-23 (Pubitemid 23284670)
57. Haynes JC, Machtay M, Weber RS, Weinstein GS, Chalian AA, Rosenthal DI: Relative risk of stroke in head and neck carcinoma patients treated with external cervical irradiation. Laryngoscope 2002; 112:1883-7
58. Abayomi OK: Neck irradiation, carotid injury and its consequences. Oral Oncol 2004; 40:872-8 (Pubitemid 39369558)
59. Lewis AF, Mullis TC, Wein RO, Eby TL: Postoperative carotid spasm in the setting of head and neck surgery. Am J Otolaryngol 2008; 29:291-4
60. Osguthorpe JD, Adkins WY: Carotid arteriospasm. Laryngoscope 1985; 95:942-4 (Pubitemid 15049874)
61. Smith PG, Killeen TE: Carotid artery vasospasm complicating extensive skull base surgery: Cause, prevention, and management. Otolaryngol Head Neck Surg 1987; 97:1-7 (Pubitemid 17097863)
62. Pohl A, Cullen DJ: Cerebral ischemia during shoulder sur-gery in the upright position: A case series. J Clin Anesth 2005; 17:463-9 (Pubitemid 41317994)
63. Tissington Tatlow WF, Bammer HG: Syndrome of vertebral artery compression. Neurology 1957; 7:331-40
64. Friedman DJ, Parnes NZ, Zimmer Z, Higgins LD, Warner JJ: Prevalence of cerebrovascular events during shoulder surgery and association with patient position. Orthopedics 2009; 32:256
65. Slater JP, Guarino T, Stack J, Vinod K, Bustami RT, Brown JM III, Rodriguez AL, Magovern CJ, Zaubler T, Freundlich K, Parr GV: Cerebral oxygen desaturation predicts cognitive decline and longer hospital stay after cardiac surgery. Ann Thorac Surg 2009; 87:36-44
66. Bangalore S, Wetterslev J, Pranesh S, Sawhney S, Gluud C, Messerli FH: Perioperative beta blockers in patients having non-cardiac surgery: A meta-analysis. Lancet 2008; 372: 1962-76
67. Devereaux PJ, Yang H, Yusuf S, Guyatt G, Leslie K, Villar JC, Xavier D, Chrolavicius S, Greenspan L, Pogue J, Pais P, Liu L, Xu S, Malaga G, Avezum A, Chan M, Montori VM, Jacka M, Choi P: Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): A randomised controlled trial. Lancet 2008; 371:1839-47
68. Ballotta E, Renon L, Da Giau G, Barbon B, De Rossi A, Baracchini C: Prospective randomized study on asymptomatic severe carotid stenosis and perioperative stroke risk in patients undergoing major vascular surgery: Prophylactic or deferred carotid endarterectomy? Ann Vasc Surg 2005; 19: 876-81 (Pubitemid 41570063)
69. Agnoli A, Fieschi C, Bozzao L, Battistini N, Prencipe M: Autoregulation of cerebral blood flow. Studies during druginduced hypertension in normal subjects and in patients with cerebral vascular diseases. Circulation 1968; 38: 800-12
70. Dawson SL, Blake MJ, Panerai RB, Potter JF: Dynamic but not static cerebral autoregulation is impaired in acute ischaemic stroke. Cerebrovasc Dis 2000; 10:126-32 (Pubitemid 30107507)
71. Rubin G, Levy EI, Scarrow AM, Firlik AD, Karakus A, Wechsler L, Jungreis CA, Yonas H: Remote effects of acute ischemic stroke: A xenon CT cerebral blood flow study. Cerebrovasc Dis 2000; 10:221-8 (Pubitemid 30219250)
72. Dawson SL, Panerai RB, Potter JF: Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke. Cerebrovasc Dis 2003; 16:69-75 (Pubitemid 36676999)
73. Aries MJ, Elting JW, De Keyser J, Kremer BP, Vroomen PC: Cerebral autoregulation in stroke: A review of transcranial Doppler studies. Stroke 2010; 41:2697-704
74. Blacker DJ, Flemming KD, Link MJ, Brown RD, Jr: The preoperative cerebrovascular consultation: Common cerebrovascular questions before general or cardiac surgery. Mayo Clin Proc 2004; 79: 223-9 (Pubitemid 38140806)
75. Liapis CD, Bell PR, Mikhailidis D, Sivenius J, Nicolaides A, Fernandes e Fernandes J, Biasi G, Norgren L: ESVS guidelines. Invasive treatment for carotid stenosis: Indications, techniques. Eur J Vasc Endovasc Surg 2009; 37:1-19
76. Spence JD: Secondary stroke prevention. Nat Rev Neurol 2010; 6:477-86
77. Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J, Pan H, Peto R, Potter J, Rahimi K, Rau A, Robertson S, Streifler J, Thomas D; Asymptomatic Carotid Surgery Trial (ACST-1) Collaborative Group: 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): A multicentre randomised trial. Lancet 2010; 376:1074-84
78. Epstein AE, Alexander JC, Gutterman DD, Maisel W, Wharton JM: Anticoagulation: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery. Chest 2005; 128:24S-7S (Pubitemid 41135934)
79. Douketis JD, Berger PB, Dunn AS, Jaffer AK, Spyropoulos AC, Becker RC, Ansell J: The perioperative management of antithrombotic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133:299S-339S (Pubitemid 351894915)
80. Garcia DA, Regan S, Henault LE, Upadhyay A, Baker J, Othman M, Hylek EM: Risk of thromboembolism with shortterm interruption of warfarin therapy. Arch Intern Med 2008; 168:63-9
81. McKenna R: Abnormal coagulation in the postoperative period contributing to excessive bleeding. Med Clin North Am 2001; 85:1277-310 (Pubitemid 32862143)
82. Torn M, Rosendaal FR: Oral anticoagulation in surgical procedures: Risks and recommendations. Br J Haematol 2003; 123:676-82 (Pubitemid 37468065)
83. Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet 2000; 355:1295-302
84. Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, Ramirez C, Sabate M, Jimenez-Quevedo P, Hernandez R, Moreno R, Escaned J, Alfonso F, Banuelos C, Costa MA, Bass TA, Macaya C: Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease. Diabetes 2006; 55: 780-4 (Pubitemid 43343236)
85. O'Riordan JM, Margey RJ, Blake G, O'Connell PR: Antiplatelet agents in the perioperative period. Arch Surg 2009; 144:69-76
86. Momjian-Mayor I, Barron J-C: The pathophysiology of watershed infarcts. Stroke 2005; 36:567-77
87. Kapoor K, Singh B, Dewan LI: Variations in the configuration of the circle of Willis. Anat Sci Int 2008; 83:96-106 (Pubitemid 351560248)
88. Bijker JB, van Klei WA, Kappen TH, van Wolfswinkel L, Moons KG, Kalkman CJ: Incidence of intraoperative hypotension as a function of the chosen definition: Literature definitions applied to a retrospective cohort using automated data collection. ANESTHESIOLOGY 2007; 107:213-20 (Pubitemid 47196483)
89. Bandera E, Botteri M, Minelli C, Sutton A, Abrams KR, Latronico N: Cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke: A systematic review. Stroke 2006; 37:1334-9 (Pubitemid 43731886)
90. Blacker DJ, Flemming KD, Wijdicks EF: Risk of ischemic stroke in patients with symptomatic vertebrobasilar stenosis undergoing surgical procedures. Stroke 2003; 34: 2659-63 (Pubitemid 37392761)
91. Larsen FS, Olsen KS, Hansen BA, Paulson OB, Knudsen GM: Transcranial Doppler is valid for determination of the lower limit of cerebral blood flow autoregulation. Stroke 1994; 25:1985-8 (Pubitemid 24291284)
92. Chillon J-M, Baumbach GL: Autoregulation: Arterial and Intracranial pressure, Cerebral Blood Flow and Metabolism, 2nd edition. Edited by Edvinsson L, Krause DN. Philadelphia, Lippincott Williams & Wilkins, 2002, pp395-412
93. Millar-Craig MW, Bishop CN, Raftery EB: Circadian variation of blood-pressure. Lancet 1978; 1:795-7
94. Howell SJ, Sear JW, Foëx P: Hypertension, hypertensive heart disease and perioperative cardiac risk. Br J Anaesth 2004; 92:570-83 (Pubitemid 38443862)
95. Soo JC, Lacey S, Kluger R, Silbert BS: Defining intra-operative hypotension-a pilot comparison of blood pressure during sleep and general anaesthesia. Anaesthesia 2011; 66: 354-60
96. Lipshutz AK, Gropper MA: Perioperative glycemic control: An evidence-based review. ANESTHESIOLOGY 2009; 110: 408-21
97. Duning T, Ellger B: Is hypoglycaemia dangerous? Best Pract Res Clin Anaesthesiol 2009; 23:473-85
98. van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lau-wers P, Bouillon R: Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345:1359-67
99. Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, Johnson MG, Williams AR, Cutshall SM, Mundy LM, Rizza RA, McMahon MM: Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: A randomized trial. Ann Intern Med 2007; 146:233-43 (Pubitemid 351650609)
100. Griesdale DE, de Souza RJ, van Dam RM, Heyland DK, Cook DJ, Malhotra A, Dhaliwal R, Henderson WR, Chittock DR, Finfer S, Talmor D: Intensive insulin therapy and mortality among critically ill patients: A meta-analysis including NICESUGAR study data. CMAJ 2009; 180:821-7
101. Marik PE, Preiser JC: Toward understanding tight glycemic control in the ICU: A systematic review and metaanalysis. Chest 2010; 137:544-51
102. Moghissi ES, Korytkowski MT, DiNardo M, Einhorn D, Hellman R, Hirsch IB, Inzucchi SE, Ismail-Beigi F, Kirkman MS, Umpierrez GE; American Association of Clinical Endocrinologists; American Diabetes Association: American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care 2009; 32:1119-31
103. Blanco M, Nombela F, Castellanos M, Rodriguez-Yanez M, Garcia-Gil M, Leira R, Lizasoain I, Serena J, Vivancos J, Moro MA, Davalos A, Castillo J: Statin treatment withdrawal in ischemic stroke: A controlled randomized study. Neurology 2007; 69:904-10 (Pubitemid 47329591)
104. Ní Chróinín D, Callaly EL, Duggan J, Merwick A, Hannon N, Sheehan O, Marnane M, Horgan G, Williams EB, Harris D, Kyne L, McCormack PM, Moroney J, Grant T, Williams D, Daly L, Kelly PJ: Association between acute statin therapy, survival, and improved functional outcome after ischemic stroke: The north Dublin population stroke study. Stroke 2011; 42:1021-9
105. Grocott HP, White WD, Morris RW, Podgoreanu MV, Mathew JP, Nielsen DM, Schwinn DA, Newman MF: Genetic polymorphisms and the risk of stroke after cardiac surgery. Stroke 2005; 36:1854-8 (Pubitemid 41266513)
106. Lanktree MB, Dichgans M, Hegele RA: Advances in genomic analysis of stroke: What have we learned and where are we headed? Stroke; 2010; 41:825-32
107. Rodgers A, Walker N, Schug S, McKee A, Kehlet H, van Zundert A, Sage D, Futter M, Saville G, Clark T, MacMahon S: Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results from overview of randomised trials. BMJ 2000; 321:1493
108. Rerkasem K, Rothwell PM: Local versus general anesthetic for carotid endarterectomy. Stroke 2009; 40:e584-5
109. Alberts MJ, Brass LM, Perry A, Webb D, Dawson DV: Evaluation times for patients with in-hospital strokes. Stroke 1993; 24:1817-22 (Pubitemid 23352709)
110. Nilanont Y, Komoltri C, Saposnik G, Cote R, Di Legge S, Jin Y, Prayoonwiwat N, Poungvarin N, Hachinski V: The Canadian Neurological Scale and the NIHSS: Development and validation of a simple conversion model. Cerebrovasc Dis 2010; 30:120-6
111. Whiteley WN, Wardlaw JM, Dennis MS, Sandercock PA. Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: A crosssectional study. J Neurol Neurosurg Psychiatry 2011; 82: 1006-10
112. Byrne B, O'Halloran P, Cardwell C. Accuracy of stroke diagnosis by registered nurses using the ROSIER tool compared to doctors using neurological assessment on a stroke unit: A prospective audit. Int J Nurs Stud 2011; 48:979-85
113. Adams HP, Jr., del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, Wijdicks EF: Guidelines for the early management of adults with ischemic stroke: A guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Stroke 2007; 38:1655-711
114. Mullins ME, Schaefer PW, Sorensen AG, Halpern EF, Ay H, He J, Koroshetz WJ, Gonzalez RG: CT and conventional and diffusion-weighted MR imaging in acute stroke: Study in 691 patients at presentation to the emergency department. Radiology 2002; 224:353-60 (Pubitemid 34809112)
115. Azzimondi G, Bassein L, Nonino F, Fiorani L, Vignatelli L, Re G, D'Alessandro R: Fever in acute stroke worsens prognosis. A prospective study. Stroke 1995; 26:2040-3
116. Reith J, Jorgensen HS, Pedersen PM, Nakayama H, Raaschou HO, Jeppesen LL, Olsen TS: Body temperature in acute stroke: Relation to stroke severity, infarct size, mortality, and outcome. Lancet 1996; 347:422-5 (Pubitemid 26054066)