Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite

eLife

Volumn 2014, Issue 3, 2014, Pages

  Clingman, Carina C ^a   Deveau, Laura M ^a   Hay, Samantha A ^a   Genga, Ryan M ^a   Shandilya, Shivender M D ^a   Massi, Francesca ^a   Ryder, Sean P ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; APTAMER; AURINTRICARBOXYLIC ACID; FATTY ACID BINDING PROTEIN; MERCAPTOETHANOL; MONOUNSATURATED FATTY ACID; MUSASHI PROTEIN; OLEIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PROTEIN; RECOMBINANT PROTEIN; RNA BINDING PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; MSI1H PROTEIN, MOUSE; NERVE PROTEIN;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CIRCULAR DICHROISM; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DOSE RESPONSE; FATTY ACID SYNTHESIS; FLUORESCENCE ANALYSIS; FLUORESCENCE POLARIZATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIPIDOMICS; MASS SPECTROMETRY; METABOLITE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NEUROBLASTOMA CELL LINE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OLIGODENDROGLIA; PLURIPOTENT STEM CELL; PROTEIN PURIFICATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; STRUCTURE ANALYSIS; WESTERN BLOTTING; ANIMAL; BINDING SITE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; STEM CELL; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ALLOSTERIC SITE; AMINO ACID MOTIFS; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MICE; MOLECULAR DYNAMICS SIMULATION; NERVE TISSUE PROTEINS; OLEIC ACID; PLURIPOTENT STEM CELLS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA-BINDING PROTEINS; STEAROYL-COA DESATURASE; STEM CELLS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84904438534     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.02848     Document Type: Article

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