Neurogenic marker abnormalities in the hippocampus in dementia with Lewy bodies

Hippocampus

Volumn 21, Issue 10, 2011, Pages 1126-1136

  Johnson, Mary ^a   Ekonomou, Antigoni ^b   Hobbs, Carl ^b   Ballard, Clive G ^b   Perry, Robert H ^c   Perry, Elaine K ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

Hippocampus; Musashi 1; Subgranular layer; Subventricular zone

Indexed keywords

ALPHA SYNUCLEIN; CELL MARKER; CHOLINE ACETYLTRANSFERASE; CYCLINE; DOUBLECORTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MUSASHI 1 PROTEIN; NESTIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; EPENDYMA CELL; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PRIORITY JOURNAL; SCHOOL CHILD; STEM CELL NICHE; SUBGRANULAR LAYER; SUBVENTRICULAR ZONE;

AGED; AGED, 80 AND OVER; ALPHA-SYNUCLEIN; ASTROCYTES; CILIA; EPITHELIAL CELLS; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; LATERAL VENTRICLES; LEWY BODIES; LEWY BODY DISEASE; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; NEUROPEPTIDES; PROLIFERATING CELL NUCLEAR ANTIGEN; RETROSPECTIVE STUDIES; RNA-BINDING PROTEINS; TISSUE BANKS;

EID: 80053118710     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20826     Document Type: Article

References (58)

1. Aponso PM, Faull RL, Connor B. 2008. Increased progenitor cell proliferation and astrogenesis in the partial progressive 6-hydroxydopamine model of Parkinson's disease. Neuroscience 151: 1142-1153.
2. Bar M. 2009. A cognitive neuroscience hypothesis of mood and depression. Trends Cogn Sci 13: 456-463.
3. Bernier PJ, Vinet J, Cossette M, Parent A. 2000. Characterization of the subventricular zone of the adult human brain: evidence for the involvement of Bcl-2. Neurosci Res 37: 67-78.
4. Betts-Henderson J, Jaros E, Krishnan KJ, Perry RH, Reeve AK, Schaefer AM, Taylor RW, Turnbull DM. 2009. Alpha-synuclein pathology and Parkinsonism associated with POLG1 mutations and multiple mitochondrial DNA deletions. Neuropathol Appl Neurobiol 35: 120-124.
5. Boldrini M, Underwood MD, Hen R, Rosoklija GB, Dwork AJ, John Mann J, Arango V. 2009. Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology 34: 2376-2389.
6. Brown JP, Couillard-Despres S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG. 2003. Transient expression of doublecortin during adult neurogenesis. J Comp Neurol 467: 1-10.
7. Calza L, Giuliani A, Fernandez M, Pirondi S, D'Intino G, Aloe L, Giardino L. 2003. Neural stem cells and cholinergic neurons: Regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor. Proc Natl Acad Sci USA 100: 7325-7330.
8. Carlén M, Meletis K, Göritz C, Darsalia V, Evergren E, Tanigaki K, Amendola M, Barnabé-Heider F, Yeung MS, Naldini L, Honjo T, Kokaia Z, Shupliakov O, Cassidy RM, Lindvall O, Frisén J. 2009. Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat Neurosci 12: 259-267.
9. Cave JW, Baker H. 2009. Dopamine systems in the forebrain. Adv Exp Med Biol 651: 15-35.
10. Chojnacki AK, Mak GK, Weiss S. 2009. Identity crisis for adult periventricular neural stem cells: Subventricular zone astrocytes, ependymal cells or both? Nat Rev Neurosci 10: 153-163.
11. Cohen JE, Zimmerman G, Melamed-Book N, Friedman A, Dori A, Soreq H. 2008. Transgenic inactivation of AChsterase impairs homeostasis in mouse hippocampal granule cells. Hippocampus 18: 182-192.
12. Cooper-Kuhn CM, Winkler J, Kuhn HG. 2004. Decreased neurogenesis after cholinergic forebrain lesion in the adult rat. J Neurosci Res 77: 155-165.
13. Crespel A, Rigau V, Coubes P, Rousset MC, de Bock F, Okano H, Baldy-Moulinier M, Bockaert J, Lerner-Natoli M. 2005. Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiol Dis 19: 436-450.
14. Curtis MA, Penney EB, Pearson J, Dragunow M, Connor B, Faull RL. 2005. The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain. Neuroscience 132: 777-788.
15. Danzer SC. 2008. Postnatal and adult neurogenesis in the development of human disease. Neuroscientist 14: 446-458.
16. Drapeau E, Mayo W, Aurousseau C, Le Moal M, Piazza PV, Abrous DN. 2003. Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proc Natl Acad Sci USA 100: 14385-14390.
17. Eisch AJ, Cameron HA, Encinas JM, Meltzer LA, Ming GL, Overstreet-Wadiche LS. 2008. Adult neurogenesis, mental health, and mental illness: Hope or hype? J Neurosci 28: 11785-11791.
18. Eriksson PS, Perfilieva E, Bjork-Eriksson T, Alborn AM, Nordborg C, Peterson DA, Gage FH. 1998. Neurogenesis in the adult human hippocampus. Nat Med 4: 1313-1317.
19. Frechette M, Rennie K, Pappas BA. 2009. Developmental forebrain cholinergic lesion and environmental enrichment: Behaviour, CA1 cytoarchitecture and neurogenesis. Brain Res 1252: 172-182.
20. Gleason D, Fallon JH, Guerra M, Liu JC, Bryant PJ. 2008. Ependymal stem cells divide asymmetrically and transfer progeny into the subventricular zone when activated by injury. Neuroscience 156: 81-88.
21. Goldman SA. 1998. Adult neurogenesis: From canaries to the clinic. J Neurobiol 36: 267-286.
22. Hagg T. 2009. From neurotransmitters to neurotrophic factors to neurogenesis. Neuroscientist 15: 20-27.
23. Hoglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, Hirsch EC. 2004. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci 7: 726-735.
24. Jin K, Peel AL, Mao XO, Xie L, Cottrell BA, Henshall DC, Greenberg DA. 2004. Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci USA 101: 343-347.
25. Jin K, Xie L, Mao XO, Greenberg DA. 2006. Alzheimer's disease drugs promote neurogenesis. Brain Res 1085: 183-188.
26. Kanemura Y, Sakakibara S, Okano H. 2002. Identification of Musashi1-positive cells in human normal and neoplastic neuroepithelial tissues by immunohistochemical methods. Methods Mol Biol 198: 273-281.
27. Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH. 2006. Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci USA 103: 780-785.
28. Kotani S, Yamauchi T, Teramoto T, Ogura H. 2008. Donepezil, an AChsterase inhibitor, enhances adult hippocampal neurogenesis. Chem Biol Interact 175: 227-230.
29. Kronenberg G, Wang LP, Geraerts M, Babu H, Synowitz M, Vicens P, Lutsch G, Glass R, Yamaguchi M, Baekelandt V, Debyser Z, Kettenmann H, Kempermann G. 2007. Local origin and activity-dependent generation of nestin-expressing protoplasmic astrocytes in CA1. Brain Struct Funct 212: 19-35.
30. Kruglyakova EP, Khovryakov AV, Shikhanov NP, Maccann GM, II, Vael I, Kruglyakov PP, Sosunov AA. 2005. Nestin-expressing cells in the human hippocampus. Neurosci Behav Physiol 35: 891-897.
31. Kuhn HG, Dickinson-Anson H, Gage FH. 1996. Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation. J Neurosci 16: 2027-2033.
32. Liu YW, Curtis MA, Gibbons HM, Mee EW, Bergin PS, Teoh HH, Connor B, Dragunow M, Faull RL. 2008. Doublecortin expression in the normal and epileptic adult human brain. Eur J Neurosci 28: 2254-2265.
33. Marxreiter F, Nuber S, Kandasamy M, Klucken J, Aigner R, Burgmayer R, Couillard-Despres S, Riess O, Winkler J, Winner B. 2009. Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein. Eur J Neurosci 29: 879-890.
34. Mattiesen WR, Tauber SC, Gerber J, Bunkowski S, Bruck W, Nau R. 2009. Increased neurogenesis after hypoxic-ischemic encephalopathy in humans is age related. Acta Neuropathol 117: 525-534.
35. McKeith I, Mintzer J, Aarsland D, Burn D, Chiu H, Cohen-Mansfield J, Dickson D, Dubois B, Duda JE, Feldman H, Gauthier S, Halliday G, Lawlor B, Lippa C, Lopez OL, Carlos Machado J, O'Brien J, Playfer J, Reid W; International Psychogeriatric Association Expert Meeting on DLB. 2004. Dementia with Lewy bodies. Lancet Neurol 3: 19-28.
36. McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, Costa D, Del Ser T, Dubois B, Galasko D, Gauthier S, Goetz CG, Gomez-Tortosa E, Halliday G, Hansen LA, Hardy J, Iwatsubo T, Kalaria RN, Kaufer D, Kenny RA, Korczyn A, Kosaka K, Lee VM, Lees A, Litvan I, Londos E, Lopez OL, Minoshima S, Mizuno Y, Molina JA, Mukaetova-Ladinska EB, Pasquier F, Perry RH, Schulz JB, Trojanowski JQ, Yamada M.; Consortium on DLB. 2005. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium. Neurology 65: 1863-1872.
37. Mori M, Jefferson JJ, Hummel M, Garbe DS. 2008. CNTF: A putative link between dopamine D2 receptors and neurogenesis. J Neurosci 28: 5867-5869.
38. Muller S, Chakrapani BP, Schwegler H, Hofmann HD, Kirsch M. 2009. Neurogenesis in the dentate gyrus depends on ciliary neurotrophic factor and signal transducer and activator of transcription 3 signaling. Stem Cells 27: 431-441.
39. Naumann N, Alpár A, Ueberham U, Arendt T, Gärtner U. 2009. Transgenic expression of human wild-type amyloid precursor protein decreases neurogenesis in the adult hippocampus. Hippocampus. Aug. 27. [Epub ahead of print].
40. Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. 2008. Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci 28: 2471-2484.
41. Okano H, Imai T, Okabe M. 2002. Musashi: A translational regulator of cell fate. J Cell Sci 115(Pt 7): 1355-1359.
42. Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. 2005. Function of RNA-binding protein Musashi-1 in stem cells. Exp Cell Res 306: 349-356.
43. Parent JM. 2002. The role of seizure-induced neurogenesis in epileptogenesis and brain repair. Epilepsy Res 50(1-2): 179-189.
44. Piggott MA, Marshall EF, Thomas N, Lloyd S, Court JA, Jaros E, Burn D, Johnson M, Perry RH, McKeith IG, Ballard C, Perry EK. 1999. Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: Rostrocaudal distribution. Brain 122 (Pt 8): 1449-1468.
45. Quinones-Hinojosa A, Chaichana K. 2007. The human subventricular zone: A source of new cells and a potential source of brain tumors. Exp Neurol 205: 313-324.
46. Quinones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perez O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriguez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A. 2006. Cellular composition and cytoarchitecture of the adult human subventricular zone: A niche of neural stem cells. J Comp Neurol 494: 415-434.
47. Quinones-Hinojosa A, Sanai N, Gonzalez-Perez O, Garcia-Verdugo JM. 2007. The human brain subventricular zone: Stem cells in this niche and its organization. Neurosurg Clin N Am 18: 15-20, vii.
48. Reif A, Fritzen S, Finger M, Strobel A, Lauer M, Schmitt A, Lesch KP. 2006. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol Psychiatry 11: 514-522.
49. Sanai N, Tramontin AD, Quiñones-Hinojosa A, Barbaro NM, Gupta N, Kunwar S, Lawton MT, McDermott MW, Parsa AT, Manuel-García Verdugo J, Berger MS, Alvarez-Buylla A. 2004. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature 427: 740-744.
50. Shyu WC, Lin SZ, Yang HI, Tzeng YS, Pang CY, Yen PS, Li H. 2004. Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells. Circulation 110: 1847-1854.
51. Sotthibundhu A, Li QX, Thangnipon W, Coulson EJ. 2009. Abeta (1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor. Neurobiol Aging 30: 1975-1985.
52. Taupin P. 2009. Adult neurogenesis, neural stem cells and Alzheimer's disease: Developments, limitations, problems and promises. Curr Alzheimer Res 6: 461-470.
53. Thored P, Arvidsson A, Cacci E, Ahlenius H, Kallur T, Darsalia V, Ekdahl CT, Kokaia Z, Lindvall O. 2006. Persistent production of neurons from adult brain stem cells during recovery after stroke. Stem Cells 24: 739-747.
54. Verret L, Jankowsky JL, Xu GM, Borchelt DR, Rampon C. 2007. Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci 27: 6771-6780.
55. Waldau B, Shetty AK. 2008. Behavior of neural stem cells in the Alzheimer's brain. Cell Mol Life Sci 65: 2372-2384.
56. Winner B, Lie DC, Rockenstein E, Aigner R, Aigner L, Masliah E, Kuhn HG, Winkler J. 2004. Human wild-type alpha-synuclein impairs neurogenesis. J Neuropathol Exp Neurol 63: 1155-1166.
57. Zhang C, McNeil E, Dressler L, Siman R. 2007. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Exp Neurol 204: 77-87.
58. Ziabreva I, Ballard C, Johnson M, Larsen JP, McKeith I, Perry R, Aarsland D, Perry E. 2007. Loss of Musashi1 in Lewy body dementia associated with cholinergic deficit. Neuropathol Appl Neurobiol 33: 586-590.