-
1
-
-
84857145742
-
The nuclear receptor signalling scaffold: Insights from full-length structures
-
Nwachukwu, J. C., Nettles, K. W. The nuclear receptor signalling scaffold: insights from full-length structures. EMBO J. 31, 251-253 (2012).
-
(2012)
EMBO J
, vol.31
, pp. 251-253
-
-
Nwachukwu, J.C.1
Nettles, K.W.2
-
2
-
-
84875363845
-
Multidomain integration in the structure of the HNF-4alpha nuclear receptor complex
-
Chandra, V. et al. Multidomain integration in the structure of the HNF-4alpha nuclear receptor complex. Nature 495, 394-398 (2013).
-
(2013)
Nature
, vol.495
, pp. 394-398
-
-
Chandra, V.1
-
3
-
-
56749130032
-
Structure of the intact PPAR-gamma-RXR-alpha nuclear receptor complex on DNA
-
Chandra, V. et al. Structure of the intact PPAR-gamma-RXR-alpha nuclear receptor complex on DNA. Nature 456, 350-356 (2008).
-
(2008)
Nature
, vol.456
, pp. 350-356
-
-
Chandra, V.1
-
4
-
-
84857183093
-
Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA
-
Orlov, I., Rochel, N., Moras, D., Klaholz, B. P. Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA. EMBO J. 31, 291-300 (2012).
-
(2012)
EMBO J
, vol.31
, pp. 291-300
-
-
Orlov, I.1
Rochel, N.2
Moras, D.3
Klaholz, B.P.4
-
5
-
-
79955581636
-
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings
-
Rochel, N. et al. Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings. Nat. Struct. Mol. Biol. 18, 564-570 (2011).
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 564-570
-
-
Rochel, N.1
-
6
-
-
79955586601
-
DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex
-
Zhang, J. et al. DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex. Nat. Struct. Mol. Biol. 18, 556-563 (2011).
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 556-563
-
-
Zhang, J.1
-
7
-
-
33646772536
-
The nuclear receptor superfamily and drug discovery
-
Moore, J. T., Collins, J. L., Pearce, K. H. The nuclear receptor superfamily and drug discovery. Chem. Med. Chem. 1, 504-523 (2006).
-
(2006)
Chem. Med. Chem
, vol.1
, pp. 504-523
-
-
Moore, J.T.1
Collins, J.L.2
Pearce, K.H.3
-
8
-
-
0029643780
-
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid
-
Renaud, J. P. et al. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature 378, 681-689 (1995).
-
(1995)
Nature
, vol.378
, pp. 681-689
-
-
Renaud, J.P.1
-
9
-
-
3242784885
-
Mechanism of the nuclear receptor molecular switch
-
Nagy, L., Schwabe, J. W. Mechanism of the nuclear receptor molecular switch. Trends Biochem. Sci. 29, 317-324 (2004).
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 317-324
-
-
Nagy, L.1
Schwabe, J.W.2
-
10
-
-
80053131732
-
Antidiabetic actions of a non-agonist PPARgamma ligand blocking Cdk5-mediated phosphorylation
-
Choi, J. H. et al. Antidiabetic actions of a non-agonist PPARgamma ligand blocking Cdk5-mediated phosphorylation. Nature 477, 477-481 (2011).
-
(2011)
Nature
, vol.477
, pp. 477-481
-
-
Choi, J.H.1
-
11
-
-
77954941113
-
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5
-
Choi, J. H. et al. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature 466, 451-456 (2010).
-
(2010)
Nature
, vol.466
, pp. 451-456
-
-
Choi, J.H.1
-
12
-
-
84855795379
-
Ligand and receptor dynamics contribute to the mechanism of graded PPARg agonism
-
Hughes, T. S. et al. Ligand and receptor dynamics contribute to the mechanism of graded PPARg agonism. Structure 20, 139-150 (2012).
-
(2012)
Structure
, vol.20
, pp. 139-150
-
-
Hughes, T.S.1
-
13
-
-
35148887302
-
Partial agonists activate PPARgamma using a helix 12 independent mechanism
-
Bruning, J. B. et al. Partial agonists activate PPARgamma using a helix 12 independent mechanism. Structure 15, 1258-1271 (2007).
-
(2007)
Structure
, vol.15
, pp. 1258-1271
-
-
Bruning, J.B.1
-
14
-
-
77957766183
-
The nuclear receptor PPARgamma individually responds to serotonin-and fatty acid-metabolites
-
Waku, T. et al. The nuclear receptor PPARgamma individually responds to serotonin-and fatty acid-metabolites. EMBO J. 29, 3395-3407 (2010).
-
(2010)
EMBO J
, vol.29
, pp. 3395-3407
-
-
Waku, T.1
-
15
-
-
10644293716
-
Benzoyl 2-methyl indoles as selective PPARgamma modulators
-
Acton, 3rd J. J. et al. Benzoyl 2-methyl indoles as selective PPARgamma modulators. Bioorg. Med. Chem. Lett. 15, 357-362 (2005).
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 357-362
-
-
Acton, J.J.1
-
16
-
-
24344484674
-
Sequential backbone assignment of peroxisome proliferatoractivated receptor-gamma ligand binding domain
-
Riepl, H. et al. Sequential backbone assignment of peroxisome proliferatoractivated receptor-gamma ligand binding domain. J. Biomol. NMR 32, 259 (2005).
-
(2005)
J. Biomol. NMR
, vol.32
, pp. 259
-
-
Riepl, H.1
-
17
-
-
79958837339
-
An introduction to NMR-based approaches for measuring protein dynamics
-
Kleckner, I. R., Foster, M. P. An introduction to NMR-based approaches for measuring protein dynamics. Biochim. Biophys. Acta 1814, 942-968 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1814
, pp. 942-968
-
-
Kleckner, I.R.1
Foster, M.P.2
-
18
-
-
80051791753
-
Ligand entry pathways in the ligand binding domain of PPARgamma receptor
-
Aci-Seche, S., Genest, M., Garnier, N. Ligand entry pathways in the ligand binding domain of PPARgamma receptor. FEBS Lett. 585, 2599-2603 (2011).
-
(2011)
FEBS Lett
, vol.585
, pp. 2599-2603
-
-
Aci-Seche, S.1
Genest, M.2
Garnier, N.3
-
19
-
-
41049092350
-
Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations
-
Genest, D. et al. Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations. Eur. Biophys. J. 37, 369-379 (2008).
-
(2008)
Eur. Biophys. J
, vol.37
, pp. 369-379
-
-
Genest, D.1
-
20
-
-
18444412555
-
Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662
-
Leesnitzer, L. M. et al. Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. Biochemistry 41, 6640-6650 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 6640-6650
-
-
Leesnitzer, L.M.1
-
21
-
-
18844467411
-
T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities
-
Lee, G. et al. T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J. Biol. Chem. 277, 19649-19657 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19649-19657
-
-
Lee, G.1
-
22
-
-
33644539839
-
NMR distinction of single-and multiple-mode binding of small-molecule protein ligands
-
Reibarkh, M., Malia, T. J., Wagner, G. NMR distinction of single-and multiple-mode binding of small-molecule protein ligands. J. Am. Chem. Soc. 128, 2160-2161 (2006).
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 2160-2161
-
-
Reibarkh, M.1
Malia, T.J.2
Wagner, G.3
-
23
-
-
75449102617
-
Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators
-
Lamotte, Y. et al. Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators. Bioorg. Med. Chem. Lett. 20, 1399-1404 (2010).
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 1399-1404
-
-
Lamotte, Y.1
-
24
-
-
17144381253
-
Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma
-
Shiraki, T. et al. Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 280, 14145-14153 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 14145-14153
-
-
Shiraki, T.1
-
25
-
-
26444464734
-
Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma
-
Soares, A. F. et al. Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma. Biochem. Biophys. Res. Commun. 337, 521-525 (2005).
-
(2005)
Biochem. Biophys. Res. Commun
, vol.337
, pp. 521-525
-
-
Soares, A.F.1
-
26
-
-
51349100657
-
Structural basis for the activation of PPARgamma by oxidized fatty acids
-
Itoh, T. et al. Structural basis for the activation of PPARgamma by oxidized fatty acids. Nat. Struct. Mol. Biol. 15, 924-931 (2008).
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 924-931
-
-
Itoh, T.1
-
27
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma
-
Lehmann, J. M. et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270, 12953-12956 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
-
28
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
-
Nolte, R. T. et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature 395, 137-143 (1998).
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
-
29
-
-
0028972025
-
15-Deoxy-D12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARg
-
Forman, B. M. et al. 15-Deoxy-D12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARg. Cell 83, 803-812 (1995).
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
-
30
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer, S. A. et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83, 813-819 (1995).
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
-
31
-
-
49449087925
-
Molecular recognition of nitrated fatty acids by PPAR gamma
-
Li, Y. et al. Molecular recognition of nitrated fatty acids by PPAR gamma. Nat. Struct. Mol. Biol. 15, 865-867 (2008).
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 865-867
-
-
Li, Y.1
-
32
-
-
57849098033
-
Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids
-
Waku, T. et al. Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. J. Mol. Biol. 385, 188-199 (2009).
-
(2009)
J. Mol. Biol
, vol.385
, pp. 188-199
-
-
Waku, T.1
-
33
-
-
58249099266
-
Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: Novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands
-
Waku, T., Shiraki, T., Oyama, T., Morikawa, K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. FEBS Lett. 583, 320-324 (2009).
-
(2009)
FEBS Lett
, vol.583
, pp. 320-324
-
-
Waku, T.1
Shiraki, T.2
Oyama, T.3
Morikawa, K.4
-
34
-
-
79955138219
-
Comparative gene expression profiles induced by PPARgamma and PPARalpha/gamma agonists in human hepatocytes
-
Rogue, A. et al. Comparative gene expression profiles induced by PPARgamma and PPARalpha/gamma agonists in human hepatocytes. PLoS One 6, e18816 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e18816
-
-
Rogue, A.1
-
35
-
-
84861732424
-
Daidzein has neuroprotective effects through ligand-bindingindependent PPARgamma activation
-
Hurtado, O. et al. Daidzein has neuroprotective effects through ligand-bindingindependent PPARgamma activation. Neurochem. Int. 61, 119-127 (2012).
-
(2012)
Neurochem. Int
, vol.61
, pp. 119-127
-
-
Hurtado, O.1
-
36
-
-
84871393949
-
Targeting PPARgamma signaling cascade for the prevention and treatment of prostate cancer
-
Sikka, S., Chen, L., Sethi, G., Kumar, A. P. Targeting PPARgamma signaling cascade for the prevention and treatment of prostate cancer. PPAR Res. 2012, 968040 (2012).
-
(2012)
PPAR Res
, vol.2012
, pp. 968040
-
-
Sikka, S.1
Chen, L.2
Sethi, G.3
Kumar, A.P.4
-
37
-
-
79958811217
-
Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPARgamma-independent mechanism
-
Akinyeke, T. O., Stewart, L. V. Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPARgamma-independent mechanism. Cancer Biol. Ther. 11, 1046-1058 (2011).
-
(2011)
Cancer Biol. Ther
, vol.11
, pp. 1046-1058
-
-
Akinyeke, T.O.1
Stewart, L.V.2
-
38
-
-
58549099485
-
Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways
-
Lyles, B. E., Akinyeke, T. O., Moss, P. E., Stewart, L. V. Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways. Cell Cycle 8, 268-277 (2009).
-
(2009)
Cell Cycle
, vol.8
, pp. 268-277
-
-
Lyles, B.E.1
Akinyeke, T.O.2
Moss, P.E.3
Stewart, L.V.4
-
39
-
-
84859254879
-
PPAR gamma, bioactive lipids, and cancer progression
-
Robbins, G. T., Nie, D. PPAR gamma, bioactive lipids, and cancer progression. Front. Biosci. 17, 1816-1834 (2012).
-
(2012)
Front. Biosci
, vol.17
, pp. 1816-1834
-
-
Robbins, G.T.1
Nie, D.2
-
40
-
-
6444238770
-
Inhibition of cell proliferation by potential peroxisome proliferator-activated receptor (PPAR) gamma agonists and antagonists
-
Lea, M. A., Sura, M., Desbordes, C. Inhibition of cell proliferation by potential peroxisome proliferator-activated receptor (PPAR) gamma agonists and antagonists. Anticancer Res. 24, 2765-2771 (2004).
-
(2004)
Anticancer Res
, vol.24
, pp. 2765-2771
-
-
Lea, M.A.1
Sura, M.2
Desbordes, C.3
-
41
-
-
51349162561
-
Insights into PPARgamma from structures with endogenous and covalently bound ligands
-
Nettles, K. W. Insights into PPARgamma from structures with endogenous and covalently bound ligands. Nat. Struct. Mol. Biol. 15, 893-895 (2008).
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 893-895
-
-
Nettles, K.W.1
-
42
-
-
44049104049
-
T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties
-
Li, Y. et al. T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties. J. Biol. Chem. 283, 9168-9176 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9168-9176
-
-
Li, Y.1
-
43
-
-
77950442251
-
Minireview: Not picking pockets: Nuclear receptor alternate-site modulators (NRAMs
-
Moore, T. W., Mayne, C. G., Katzenellenbogen, J. A. Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs). Mol. Endocrinol. 24, 683-695 (2010).
-
(2010)
Mol. Endocrinol
, vol.24
, pp. 683-695
-
-
Moore, T.W.1
Mayne, C.G.2
Katzenellenbogen, J.A.3
-
44
-
-
33745632097
-
A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor b
-
Wang, Y. et al. A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor b. Proc. Natl Acad. Sci. USA 103, 9908-9911 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 9908-9911
-
-
Wang, Y.1
-
45
-
-
58249126793
-
Implications of the binding of tamoxifen to the coactivator recognition site of the estrogen receptor
-
Kojetin, D. J., Burris, T. P., Jensen, E. V., Khan, S. A. Implications of the binding of tamoxifen to the coactivator recognition site of the estrogen receptor. Endocr. Relat. Cancer 15, 851-870 (2008).
-
(2008)
Endocr. Relat. Cancer
, vol.15
, pp. 851-870
-
-
Kojetin, D.J.1
Burris, T.P.2
Jensen, E.V.3
Khan, S.A.4
-
46
-
-
8344221130
-
A two-site model for antiestrogen action
-
Jensen, E. V., Khan, S. A. A two-site model for antiestrogen action. Mech. Ageing Dev. 125, 679-682 (2004).
-
(2004)
Mech. Ageing Dev
, vol.125
, pp. 679-682
-
-
Jensen, E.V.1
Khan, S.A.2
-
47
-
-
82655181823
-
A conserved surface on the ligand binding domain of nuclear receptors for allosteric control
-
Buzon, V., Carbo, L. R., Estruch, S. B., Fletterick, R. J., Estebanez-Perpina, E. A conserved surface on the ligand binding domain of nuclear receptors for allosteric control. Mol. Cell Endocrinol. 348, 394-402 (2012).
-
(2012)
Mol. Cell Endocrinol
, vol.348
, pp. 394-402
-
-
Buzon, V.1
Carbo, L.R.2
Estruch, S.B.3
Fletterick, R.J.4
Estebanez-Perpina, E.5
-
48
-
-
84863336768
-
Allosteric conversation in the androgen receptor ligand-binding domain surfaces
-
Grosdidier, S. et al. Allosteric conversation in the androgen receptor ligand-binding domain surfaces. Mol. Endocrinol. 26, 1078-1090 (2012).
-
(2012)
Mol. Endocrinol
, vol.26
, pp. 1078-1090
-
-
Grosdidier, S.1
-
49
-
-
35348812462
-
A surface on the androgen receptor that allosterically regulates coactivator binding
-
Estébanez-Perpinã, E. et al. A surface on the androgen receptor that allosterically regulates coactivator binding. Proc. Natl Acad. Sci. USA 104, 16074-16079 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 16074-16079
-
-
Estébanez-Perpinã, E.1
-
50
-
-
36849059727
-
Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor
-
Estébanez-Perpinã, E. et al. Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor. Mol. Endocrinol. 21, 2919-2928 (2007).
-
(2007)
Mol. Endocrinol
, vol.21
, pp. 2919-2928
-
-
Estébanez-Perpinã, E.1
-
51
-
-
30044433051
-
Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators
-
Arnold, L. A. et al. Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators. J. Biol. Chem. 280, 43048-43055 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 43048-43055
-
-
Arnold, L.A.1
-
52
-
-
80054988658
-
Similarities and differences between two modes of antagonism of the thyroid hormone receptor
-
Sadana, P. et al. Similarities and differences between two modes of antagonism of the thyroid hormone receptor. ACS Chem. Biol. 6, 1096-1106 (2011).
-
(2011)
ACS Chem. Biol
, vol.6
, pp. 1096-1106
-
-
Sadana, P.1
-
53
-
-
4444273468
-
Identification of an alternative ligand-binding pocket in the nuclear Vitamin D receptor and its functional importance in 1alpha,25(OH)2-Vitamin D3 signaling
-
Mizwicki, M. T. et al. Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling. Proc. Natl Acad. Sci. USA 101, 12876-12881 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 12876-12881
-
-
Mizwicki, M.T.1
-
54
-
-
33947165807
-
New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model
-
Mizwicki, M. T., Bula, C. M., Bishop, J. E., Norman, A. W. New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model. J. Steroid Biochem. Mol. Biol. 103, 243-262 (2007).
-
(2007)
J. Steroid Biochem. Mol. Biol
, vol.103
, pp. 243-262
-
-
Mizwicki, M.T.1
Bula, C.M.2
Bishop, J.E.3
Norman, A.W.4
-
55
-
-
27544454645
-
A perspective on how the Vitamin D sterol/Vitamin D receptor (VDR) conformational ensemble model can potentially be used to understand the structure-function results of A-ring modified Vitamin D sterols
-
Mizwicki, M. T., Bula, C. M., Bishop, J. E., Norman, A. W. A perspective on how the Vitamin D sterol/Vitamin D receptor (VDR) conformational ensemble model can potentially be used to understand the structure-function results of A-ring modified Vitamin D sterols. J. Steroid Biochem. Mol. Biol. 97, 69-82 (2005).
-
(2005)
J. Steroid Biochem. Mol. Biol
, vol.97
, pp. 69-82
-
-
Mizwicki, M.T.1
Bula, C.M.2
Bishop, J.E.3
Norman, A.W.4
-
56
-
-
68849103260
-
The Vitamin D sterol-Vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling
-
Mizwicki, M. T., Norman, A. W. The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling. Sci. Signal. 2, re4 (2009).
-
(2009)
Sci. Signal
, vol.2
, pp. 4
-
-
Mizwicki, M.T.1
Norman, A.W.2
-
57
-
-
79960978543
-
Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP
-
Menegaz, D. et al. Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP). Mol. Endocrinol. 25, 1289-1300 (2011).
-
(2011)
Mol. Endocrinol
, vol.25
, pp. 1289-1300
-
-
Menegaz, D.1
-
58
-
-
60849095073
-
INT131: A selective modulator of PPAR gamma
-
Motani, A. et al. INT131: a selective modulator of PPAR gamma. J. Mol. Biol. 386, 1301-1311 (2009).
-
(2009)
J. Mol. Biol
, vol.386
, pp. 1301-1311
-
-
Motani, A.1
-
59
-
-
84860291442
-
Regulation of circadian behavior and metabolism by synthetic REV-ERB agonists
-
Solt, L. A. et al. Regulation of circadian behavior and metabolism by synthetic REV-ERB agonists. Nature 485, 62-68 (2012).
-
(2012)
Nature
, vol.485
, pp. 62-68
-
-
Solt, L.A.1
-
60
-
-
33846626899
-
A 1H-NMR thermometer suitable for cryoprobes
-
Findeisen, M., Brand, T., Berger, S. A 1H-NMR thermometer suitable for cryoprobes. Magn. Reson. Chem. 45, 175-178 (2007).
-
(2007)
Magn. Reson. Chem
, vol.45
, pp. 175-178
-
-
Findeisen, M.1
Brand, T.2
Berger, S.3
-
61
-
-
77949411905
-
Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins
-
Otten, R., Chu, B., Krewulak, K. D., Vogel, H. J., Mulder, F. A. Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins. J. Am. Chem. Soc. 132, 2952-2960 (2010).
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 2952-2960
-
-
Otten, R.1
Chu, B.2
Krewulak, K.D.3
Vogel, H.J.4
Mulder, F.A.5
-
62
-
-
84865166917
-
NMR line shapes and multi-state binding equilibria
-
Kovrigin, E. L. NMR line shapes and multi-state binding equilibria. J. Biomol. NMR 53, 257-270 (2012).
-
(2012)
J. Biomol. NMR
, vol.53
, pp. 257-270
-
-
Kovrigin, E.L.1
-
63
-
-
33144462544
-
Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry
-
Chalmers, M. J. et al. Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry. Anal. Chem. 78, 1005-1014 (2006).
-
(2006)
Anal. Chem
, vol.78
, pp. 1005-1014
-
-
Chalmers, M.J.1
-
64
-
-
33750617803
-
Improving digestion efficiency under H/D exchange conditions with activated pepsinogen coupled columns
-
Busby, S. A., Chalmers, M. J., Griffin, P. R. Improving digestion efficiency under H/D exchange conditions with activated pepsinogen coupled columns. Int. J. Mass. Spectrom. 259, 130-139 (2007).
-
(2007)
Int. J. Mass. Spectrom
, vol.259
, pp. 130-139
-
-
Busby, S.A.1
Chalmers, M.J.2
Griffin, P.R.3
-
65
-
-
84865763488
-
HDX workbench: Software for the analysis of H/D exchange MS data
-
Pascal, B. D. et al. HDX workbench: software for the analysis of H/D exchange MS data. J. Am. Soc. Mass. Spectrom. 23, 1512-1521 (2012).
-
(2012)
J. Am. Soc. Mass. Spectrom
, vol.23
, pp. 1512-1521
-
-
Pascal, B.D.1
-
66
-
-
76149120388
-
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
-
Trott, O., Olson, A. J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem. 31, 455-461 (2010).
-
(2010)
J. Comput. Chem
, vol.31
, pp. 455-461
-
-
Trott, O.1
Olson, A.J.2
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