Synthesis and biological activities of novel indole derivatives as potent and selective PPARγ modulators

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 4, 2010, Pages 1399-1404

  Lamotte, Yann ^a   Martres, Paul ^a   Faucher, Nicolas ^a   Laroze, Alain ^a   Grillot, Didier ^a   Ancellin, Nicolas ^a   Saintillan, Yannick ^a   Beneton, Véronique ^a   Gampe Jr , Robert T ^b  

^a GLAXOSMITHKLINE   (France)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Diabetes; Modulator; Peroxisome proliferator activated receptor; PPAR ; Telmisartan

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TELMISARTAN;

ARTICLE; CRYSTAL STRUCTURE; DRUG BIOAVAILABILITY; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BENZIMIDAZOLES; BENZOATES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PPAR GAMMA; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 75449102617     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.107     Document Type: Article

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