Yuwen02f1 suppresses LPS-induced endotoxemia and adjuvant-induced arthritis primarily through blockade of ROS formation, NFkB and MAPK activation

Biochemical Pharmacology

Volumn 85, Issue 3, 2013, Pages 385-395

  Hsu, Chun Chieh ^a   Lien, Jin Cherng ^b   Chang, Chia Wen ^a   Chang, Chien Hsin ^a   Kuo, Sheng Chu ^b   Huang, Tur Fu ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Diphenylpyrazole; Inflammatory animal; MAPK; NF B; ROS

Indexed keywords

1 (4 FLUOROBENZYL) 5 (5 ETHOXYCARBONYL 2 FURYL) 3 PHENYLPYRAZOLE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN P47; PROTEIN P67; PYRAZOLE DERIVATIVE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; YUWEN 02F1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CELL MEMBRANE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; ENDOTOXEMIA; MALE; MOUSE; NONHUMAN; PAW EDEMA; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CELL LINE; CELL MOVEMENT; CELL SURVIVAL; CYCLOOXYGENASE 2; ENDOTOXEMIA; FURANS; GENE EXPRESSION REGULATION; HUMANS; L-LACTATE DEHYDROGENASE; LIPOPROTEINS; MACROPHAGES; MALE; MICE; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; MONOCYTES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PYRAZOLES; REACTIVE OXYGEN SPECIES;

EID: 84872684244     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.11.002     Document Type: Article

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