High glucose induces enhanced expression of resistin in human U937 monocyte-like cell line by MAPK- and NF-kB-dependent mechanisms; the modulating effect of insulin

Cell and Tissue Research

Volumn 343, Issue 2, 2011, Pages 379-387

  Stan, Daniela ^a   Calin, Manuela ^a,b   Manduteanu, Ileana ^a   Pirvulescu, Monica ^a   Gan, Ana Maria ^a   Butoi, Elena Dragomir ^a   Simion, Viorel ^a   Simionescu, Maya ^a  

^a INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

^b PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

Author keywords

High glucose; Human monocytic cell line U937; Insulin; Mitogenactivated protein kinases; Nuclear factor kappa B; Resistin; Signalling pathways

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PYRROLIDINE DITHIOCARBAMATE; RESISTIN; SYNAPTOPHYSIN;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; GLUCOSE; HUMANS; IMIDAZOLES; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; NF-KAPPA B; PYRIDINES; RESISTIN; U937 CELLS; UP-REGULATION;

EID: 79953874256     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-010-1092-3     Document Type: Article

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