Danning tablets attenuates α-naphthylisothiocyanate-induced cholestasis by modulating the expression of transporters and metabolic enzymes

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Ding, Lili ^a,b   Zhang, Binfeng ^a,b   Zhan, Changsen ^a,c   Yang, Li ^a,b   Wang, Zhengtao ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai R and D Center for Standardization of Traditional Chinese Medicines   (China)

^c Hutchison MediPharma Limited   (China)

Author keywords

Cholestasis; Danning tablet; Metabolic enzyme; Transporter; naphthylisothiocyanate (ANIT)

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILE SALT EXPORT PUMP; BILIRUBIN; BILIRUBIN GLUCURONIDE; CHOLAGOGUE; CYTOCHROME P450 2B1; DANNING TABLET; GLUCURONOSYLTRANSFERASE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID BLOOD LEVEL; BILIARY EXCRETION; BILIRUBIN BLOOD LEVEL; CHOLESTASIS; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; LIVER INJURY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; TABLET; TREATMENT DURATION; UPREGULATION;

1-NAPHTHYLISOTHIOCYANATE; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BILE ACIDS AND SALTS; BILIRUBIN; BIOLOGICAL TRANSPORT; CHOLESTASIS; DRUGS, CHINESE HERBAL; LIVER; MALE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; RANDOM ALLOCATION; RATS; RATS, WISTAR;

EID: 84904275121     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-249     Document Type: Article

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