Loss of A1 adenosine receptor attenuates alpha-naphthylisothiocyanate- induced cholestatic liver injury in mice

Toxicological Sciences

Volumn 131, Issue 1, 2013, Pages 128-138

  Yang, Ping ^a   Chen, Peng ^a,b   Wang, Tao ^a   Zhan, Yibei ^a   Zhou, Mengyi ^a   Xia, Lin ^a   Cheng, Rui ^a   Guo, Yating ^a   Zhu, Lin ^c   Zhang, Jianfa ^a  

^a NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c JINLING HOSPITAL   (China)

Author keywords

A1AR; ANIT; Bile acid; Cholestasis; DPCPX

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; ADENOSINE A1 RECEPTOR; BILE ACID; BILIRUBIN; BSEP PROTEIN; CYTOCHROME P450 3A11; MDR2 PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTASIS; CONTROLLED STUDY; GENE EXPRESSION; GLOMERULUS FILTRATION RATE; HISTOPATHOLOGY; HYDROXYLATION; KIDNEY FUNCTION; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WILD TYPE;

1-NAPHTHYLISOTHIOCYANATE; ADENOSINE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; BLOTTING, WESTERN; CHOLESTASIS, EXTRAHEPATIC; CYTOCHROME P-450 CYP3A; GENE EXPRESSION; GLOMERULAR FILTRATION RATE; KIDNEY; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; P-GLYCOPROTEINS; RECEPTOR, ADENOSINE A1;

MUS;

EID: 84872417025     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs263     Document Type: Article

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