Altered integrity and decreased expression of hepatocyte tight junctions in rifampicin-induced cholestasis in mice

Toxicology and Applied Pharmacology

Volumn 240, Issue 1, 2009, Pages 26-36

  Chen, Xi ^a,b   Zhang, Cheng ^a   Wang, Hua ^a   Xu, Juan ^a   Duan, Zi Hao ^a   Zhang, Ying ^a   Yu, Tao ^a   Wei, Wei ^a   Xu, De Xiang ^a   Xu, Jian Ming ^a,b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Key Laboratory of Gastroenterology of Anhui Province   (China)

Author keywords

Cholestasis; Hepatocyte tight junctions; Occludin; Rifampicin; Zonula occludens

Indexed keywords

BILE ACID; BILIRUBIN GLUCURONIDE; CLAUDIN 1; MESSENGER RNA; OCCLUDIN; PROTEIN ZO1; PROTEIN ZO2; PROTEIN ZO3; RIFAMPICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; CHOLESTASIS; CONTROLLED STUDY; DRUG INDUCED DISEASE; FEMALE; HISTOLOGY; IMMUNOFLUORESCENCE; LIVER CELL; LIVER INJURY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH INTUBATION; TIGHT JUNCTION;

ADMINISTRATION, ORAL; ANIMALS; CHOLESTASIS, INTRAHEPATIC; FEMALE; HEPATOCYTES; MICE; MICROSCOPY, CONFOCAL; RIFAMPIN; TIGHT JUNCTIONS;

MUS;

EID: 69549114291     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.06.022     Document Type: Article

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