Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Chen, Yu Ying ^a   Hsieh, Cheng Ying ^b   Jayakumar, Thanasekaran ^a   Lin, Kuan Hung ^c   Chou, Duen Suey ^b   Lu, Wan Jung ^a   Hsu, Ming Jen ^b   Sheu, Joen Rong ^a,b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGRAPHOLIDE; CASPASE 3; DITERPENE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOPROTEIN PHOSPHATASE 2; PPP2CA PROTEIN, RAT; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE SHP 1; PTPN6 PROTEIN, RAT;

ANIMAL; APOPTOSIS; DRUG EFFECTS; FEMALE; MALE; METABOLISM; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

ANIMALS; APOPTOSIS; CASPASE 3; DITERPENES; FEMALE; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84904174944     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05651     Document Type: Article

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