Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-β peptide-induced cerebrovascular endothelial cell death

Journal of Neuroscience

Volumn 26, Issue 8, 2006, Pages 2290-2299

  Yin, Ke Jie ^a   Hsu, Chung Y ^a,b   Hu, Xiao Yan ^a   Chen, Hong ^a   Chen, Sha Wei ^a   Xu, Jan ^a   Lee, Jin Moo ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Amyloid ; Apoptosis; bim; Ceramide activated protein phosphatases; Cerebral endothelial cells; FKHRL1; Peptide

Indexed keywords

AMYLOID BETA PROTEIN; BIM PROTEIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; PEPTIDE FRAGMENT; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE TRANSFER; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; VASCULAR AMYLOIDOSIS; VIRUS VECTOR; ANIMAL; APOPTOSIS; BRAIN CIRCULATION; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBROVASCULAR CIRCULATION; ENDOTHELIAL CELLS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; MICE; PEPTIDE FRAGMENTS; PHOSPHOPROTEIN PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 33645633087     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5103-05.2006     Document Type: Article

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