Apoptosis signal-regulating kinase 1 in peptidoglycan-induced COX-2 expression in macrophages

Journal of Leukocyte Biology

Volumn 87, Issue 6, 2010, Pages 1069-1082

  Hsu, Ming Jen ^a   Chang, Chia Kai ^a   Chen, Mei Chieh ^a   Chen, Bing Chang ^a   Ma, Hon Ping ^b   Hong, Chuang Ye ^c   Lin, Chien Huang ^a,b,c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Inflammation; Monocytes macrophages; Signal transduction; Toll like receptor; Transcription factors

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOPTOSIS SIGNAL REGULATING KINASE 1; CCAAT ENHANCER BINDING PROTEIN BETA; CURCUMIN; CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; OKADAIC ACID; PALMITOYL 3 CYSTEINE SERINE LYSINE 4; PEPTIDOGLYCAN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR AGONIST; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; CEBPB PROTEIN, MOUSE; MAP3K5 PROTEIN, MOUSE; PHOSPHOPROTEIN PHOSPHATASE 2; PTGS2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING SITE; DNA BINDING; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MACROPHAGE; MONONUCLEAR CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; APOPTOSIS; CHROMATIN IMMUNOPRECIPITATION; DRUG EFFECT; DRUG POTENTIATION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CHROMATIN IMMUNOPRECIPITATION; CYCLOOXYGENASE 2; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGES; MAP KINASE KINASE KINASE 5; MICE; PEPTIDOGLYCAN; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TRANSCRIPTION FACTOR AP-1;

EID: 77954021023     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1009668     Document Type: Article

References (70)

1. Janeway Jr., C. A., Medzhitov, R. (2002) Innate immune recognition. Annu. Rev. Immunol. 20, 197-216.
2. Ulevitch, R. J., Tobias, P. S. (1995) Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13, 437-457.
3. Bone, R. C. (1994) Gram-positive organisms and sepsis. Arch. Intern. Med. 154, 26-34.
4. Annane, D., Bellissant, E., Cavaillon, J. M. (2005) Septic shock. Lancet 365, 63-78.
5. Xu, Z., Dziarski, R., Wang, Q., Swartz, K., Sakamoto, K. M., Gupta, D. (2001) Bacterial peptidoglycan-induced TNF-α transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-κB. J. Immunol. 167, 6975-6982. (Pubitemid 33144192)
6. Wang, Q., Dziarski, R., Kirschning, C. J., Muzio, M., Gupta, D. (2001) Micrococci and peptidoglycan activate TLR2→MyD88→IRAK→TRAF→ NIK→IKK→NF-κB signal transduction pathway that induces transcription of interleukin-8. Infect. Immun. 69, 2270-2276. (Pubitemid 32239694)
7. Wang, Z. M., Liu, C., Dziarski, R. (2000) Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin. J. Biol. Chem. 275, 20260-20267.
8. Dziarski, R., Jin, Y. P., Gupta, D. (1996) Differential activation of extracellular signal-regulated kinase (ERK) 1, ERK2, p38, and c-Jun NH2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan. J. Infect. Dis. 174, 777-785.
9. Bhakdi, S., Klonisch, T., Nuber, P., Fischer, W. (1991) Stimulation of monokine production by lipoteichoic acids. Infect. Immun. 59, 4614-4620.
10. Fernandez, N., Gonzalez, A., Valera, I., Alonso, S., Crespo, M. S. (2007) Mannan and peptidoglycan induce COX-2 protein in human PMN via the mammalian target of rapamycin. Eur. J. Immunol. 37, 2572-2582. (Pubitemid 47423626)
11. Valera, I., Vigo, A. G., Alonso, S., Barbolla, L., Crespo, M. S., Fernandez, N. (2007) Peptidoglycan and mannose-based molecular patterns trigger the arachidonic acid cascade in human polymorphonuclear leukocytes. J. Leukoc. Biol. 81, 925-933. (Pubitemid 46495641)
12. Vane, J. R., Bakhle, Y. S., Botting, R. M. (1998) Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol. 38, 97-120.
13. Mitchell, J. A., Larkin, S., Williams, T. J. (1995) Cyclooxygenase-2: regulation and relevance in inflammation. Biochem. Pharmacol. 50, 1535-1542.
14. Xie, W. L., Chipman, J. G., Robertson, D. L., Erikson, R. L., Simmons, D. L. (1991) Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA 88, 2692-2696.
15. Chen, B. C., Chang, Y. S., Kang, J. C., Hsu, M. J., Sheu, J. R., Chen, T. L., Teng, C. M., Lin, C. H. (2004) Peptidoglycan induces nuclear factor-κB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages. J. Biol. Chem. 279, 20889-20897.
16. Hinz, B., Brune, K. (2002) Cyclooxygenase-2-10 years later. J. Pharmacol. Exp. Ther. 300, 367-375.
17. Samad, T. A., Moore, K. A., Sapirstein, A., Billet, S., Allchorne, A., Poole, S., Bonventre, J. V., Woolf, C. J. (2001) Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410, 471-475. (Pubitemid 32240046)
18. Lin, C. H., Kuan, I. H., Lee, H. M., Lee, W. S., Sheu, J. R., Ho, Y. S., Wang, C. H., Kuo, H. P. (2001) Induction of cyclooxygenase-2 protein by lipoteichoic acid from Staphylococcus aureus in human pulmonary epithelial cells: involvement of a nuclear factor-κ B-dependent pathway. Br. J. Pharmacol. 134, 543-552.
19. Mitchell, J. A., Akarasereenont, P., Thiemermann, C., Flower, R. J., Vane, J. R. (1993) Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA 90, 11693-11697. (Pubitemid 24008705)
20. Maier, J. A., Hla, T., Maciag, T. (1990) Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J. Biol. Chem. 265, 10805-10808.
21. Williams, C. S., Mann, M., DuBois, R. N. (1999) The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 18, 7908-7916.
22. Reddy, S. T., Wadleigh, D. J., Herschman, H. R. (2000) Transcriptional regulation of the cyclooxygenase-2 gene in activated mast cells. J. Biol. Chem. 275, 3107-3113.
23. Kim, Y., Fischer, S. M. (1998) Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J. Biol. Chem. 273, 27686-27694. (Pubitemid 28500494)
24. Inoue, H., Yokoyama, C., Hara, S., Tone, Y., Tanabe, T. (1995) Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J. Biol. Chem. 270, 24965-24971.
25. Chen, J. C., Huang, K. C., Wingerd, B., Wu, W. T., Lin, W. W. (2004) HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: role of MAPK cascades and promoter elements for CREB and C/EBPβ. Exp. Cell Res. 301, 305-319. (Pubitemid 39504982)
26. Cho, Y. H., Lee, C. H., Kim, S. G. (2003) Potentiation of lipopolysaccharide-inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun Nterminal kinase-mediated activation of CCAAT/enhancer binding protein β in macrophages. Mol. Pharmacol. 63, 512-523.
27. Gorgoni, B., Caivano, M., Arizmendi, C., Poli, V. (2001) The transcription factor C/EBPβ is essential for inducible expression of the cox-2 gene in macrophages but not in fibroblasts. J. Biol. Chem. 276, 40769-40777.
28. Wadleigh, D. J., Reddy, S. T., Kopp, E., Ghosh, S., Herschman, H. R. (2000) Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages. J. Biol. Chem. 275, 6259-6266. (Pubitemid 30129916)
29. Chen, B. C., Liao, C. C., Hsu, M. J., Liao, Y. T., Lin, C. C., Sheu, J. R., Lin, C. H. (2006) Peptidoglycan-induced IL-6 production in RAW 264.7 macrophages is mediated by cyclooxygenase-2, PGE2/PGE4 receptors, protein kinase A, I κ B kinase, and NF-κ B. J. Immunol. 177, 681-693.
30. Hsu, M. J., Hsu, C. Y., Chen, B. C., Chen, M. C., Ou, G., Lin, C. H. (2007) Apoptosis signal-regulating kinase 1 in amyloid β peptide-induced cerebral endothelial cell apoptosis. J. Neurosci. 27, 5719-5729.
31. Wang, X. S., Diener, K., Jannuzzi, D., Trollinger, D., Tan, T. H., Lichenstein, H., Zukowski, M., Yao, Z. (1996) Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase. J. Biol. Chem. 271, 31607-31611. (Pubitemid 26408622)
32. Nishitoh, H., Matsuzawa, A., Tobiume, K., Saegusa, K., Takeda, K., Inoue, K., Hori, S., Kakizuka, A., Ichijo, H. (2002) ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 16, 1345-1355. (Pubitemid 34615088)
33. Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K., Ichijo, H. (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17, 2596-2606. (Pubitemid 28221195)
34. Gotoh, Y., Cooper, J. A. (1998) Reactive oxygen species- and dimerization- induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-α signal transduction. J. Biol. Chem. 273, 17477-17482. (Pubitemid 28355079)
35. Into, T., Shibata, K. (2005) Apoptosis signal-regulating kinase 1-mediated sustained p38 mitogen-activated protein kinase activation regulates mycoplasmal lipoprotein- and staphylococcal peptidoglycan-triggered Toll-like receptor 2 signaling pathways. Cell. Microbiol. 7, 1305-1317. (Pubitemid 41179423)
36. Zhang, L., Chen, J., Fu, H. (1999) Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proc. Natl. Acad. Sci. USA 96, 8511-8515.
37. Hunter, T. (2000) Signaling - 2000 and beyond. Cell 100, 113-127.
38. Yin, K. J., Hsu, C. Y., Hu, X. Y., Chen, H., Chen, S. W., Xu, J., Lee, J. M. (2006) Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-β peptide-induced cerebrovascular endothelial cell death. J. Neurosci. 26, 2290-2299.
39. Kins, S., Kurosinski, P., Nitsch, R. M., Gotz, J. (2003) Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice. Am. J. Pathol. 163, 833-843. (Pubitemid 37040120)
40. Dobrowsky, R. T., Hannun, Y. A. (1992) Ceramide stimulates a cytosolic protein phosphatase. J. Biol. Chem. 267, 5048-5051.
41. Cohen, P., Klumpp, S., Schelling, D. L. (1989) An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues. FEBS Lett. 250, 596-600. (Pubitemid 19171416)
42. He, Y., Zhang, W., Zhang, R., Zhang, H., Min, W. (2006) SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation. J. Biol. Chem. 281, 5559-5566. (Pubitemid 43847652)
43. Song, J. J., Lee, Y. J. (2005) Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop. J. Cell Biol. 170, 61-72.
44. Tengku-Muhammad, T. S., Hughes, T. R., Foka, P., Cryer, A., Ramji, D. P. (2000) Cytokine-mediated differential regulation of macrophage activator protein-1 genes. Cytokine 12, 720-726. (Pubitemid 30453505)
45. Karin, M. (1995) The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270, 16483-16486.
46. Yin, K. J., Lee, J. M., Chen, S. D., Xu, J., Hsu, C. Y. (2002) Amyloid-β induces Smac release via AP-1/Bim activation in cerebral endothelial cells. J. Neurosci. 22, 9764-9770. (Pubitemid 35332859)
47. Lee, S. K., Kim, B. S., Yang, W. S., Kim, S. B., Park, S. K., Park, J. S. (2001) High glucose induces MCP-1 expression partly via tyrosine kinase-AP-1 pathway in peritoneal mesothelial cells. Kidney Int. 60, 55-64.
48. Goldman, E. H., Chen, L., Fu, H. (2004) Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J. Biol. Chem. 279, 10442-10449.
49. Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., Kirschning, C. J. (1999) Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol. Chem. 274, 17406-17409.
50. Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., Akira, S. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-451. (Pubitemid 29504199)
51. Yoshimura, A., Lien, E., Ingalls, R. R., Tuomanen, E., Dziarski, R., Golenbock, D. (1999) Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol. 163, 1-5. (Pubitemid 29295815)
52. Travassos, L. H., Girardin, S. E., Philpott, D. J., Blanot, D., Nahori, M. A., Werts, C., Boneca, I. G. (2004) Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep. 5, 1000-1006. (Pubitemid 39534459)
53. Li, H., Nooh, M. M., Kotb, M., Re, F. (2008) Commercial peptidoglycan preparations are contaminated with superantigen-like activity that stimulates IL-17 production. J. Leukoc. Biol. 83, 409-418. (Pubitemid 351225622)
54. Dziarski, R., Gupta, D. (2005) Staphylococcus aureus peptidoglycan is a Toll-like receptor 2 activator: a reevaluation. Infect. Immun. 73, 5212-5216. (Pubitemid 41105684)
55. Singh, S., Aggarwal, B. B. (1995) Activation of transcription factor NF-κ B is suppressed by curcumin (diferuloylmethane). J. Biol. Chem. 270, 24995-25000 (corrected).
56. Jobin, C., Bradham, C. A., Russo, M. P., Juma, B., Narula, A. S., Brenner, D. A., Sartor, R. B. (1999) Curcumin blocks cytokine-mediated NF-κ B activation and proinflammatory gene expression by inhibiting inhibitory factor I-κ B kinase activity. J. Immunol. 163, 3474-3483. (Pubitemid 29431852)
57. Gupta, D., Wang, Q., Vinson, C., Dziarski, R. (1999) Bacterial peptidoglycan induces CD14-dependent activation of transcription factors CREB/ATF and AP-1. J. Biol. Chem. 274, 14012-14020.
58. Zhang, R., He, X., Liu, W., Lu, M., Hsieh, J. T., Min, W. (2003) AIP1 mediates TNF-α-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3. J. Clin. Invest. 111, 1933-1943. (Pubitemid 38057738)
59. Verheij, M., Bose, R., Lin, X. H., Yao, B., Jarvis, W. D., Grant, S., Birrer, M. J., Szabo, E., Zon, L. I., Kyriakis, J. M., Haimovitz-Friedman, A., Fuks, Z., Kolesnick, R. N. (1996) Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 380, 75-79.
60. Testi, R. (1996) Sphingomyelin breakdown and cell fate. Trends Biochem. Sci. 21, 468-471.
61. Xu, J., Yeh, C. H., Chen, S., He, L., Sensi, S. L., Canzoniero, L. M., Choi, D. W., Hsu, C. Y. (1998) Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death. J. Biol. Chem. 273, 16521-16526. (Pubitemid 28311437)
62. Chen, B. C., Chang, H. M., Hsu, M. J., Shih, C. M., Chiu, Y. H., Chiu, W. T., Lin, C. H. (2009) Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway. J. Biol. Chem. 284, 20562-20573.
63. Kang, Y. J., Wingerd, B. A., Arakawa, T., Smith, W. L. (2006) Cyclooxygenase-2 gene transcription in a macrophage model of inflammation. J. Immunol. 177, 8111-8122. (Pubitemid 44846330)
64. Caivano, M., Gorgoni, B., Cohen, P., Poli, V. (2001) The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein β (C/EBP β) and C/EBP δ transcription factors. J. Biol. Chem. 276, 48693-48701.
65. LeClair, K. P., Blanar, M. A., Sharp, P. A. (1992) The p50 subunit of NF-κ B associates with the NF-IL6 transcription factor. Proc. Natl. Acad. Sci. USA 89, 8145-8149.
66. Kinoshita, S., Akira, S., Kishimoto, T. (1992) A member of the C/EBP family, NF-IL6 β, forms a heterodimer and transcriptionally synergizes with NF-IL6. Proc. Natl. Acad. Sci. USA 89, 1473-1476.
67. Foka, P., Kousteni, S., Ramji, D. P. (2001) Molecular characterization of the Xenopus CCAAT-enhancer binding protein β gene promoter. Biochem. Biophys. Res. Commun. 285, 430-436. (Pubitemid 32918089)
68. Dean, J. L., Brook, M., Clark, A. R., Saklatvala, J. (1999) p38 Mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J. Biol. Chem. 274, 264-269. (Pubitemid 29035058)
69. Monick, M. M., Robeff, P. K., Butler, N. S., Flaherty, D. M., Carter, A. B., Peterson, M. W., Hunninghake, G. W. (2002) Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA. J. Biol. Chem. 277, 32992-33000.
70. Mbonye, U. R., Yuan, C., Harris, C. E., Sidhu, R. S., Song, I., Arakawa, T., Smith, W. L. (2008) Two distinct pathways for cyclooxygenase-2 protein degradation. J. Biol. Chem. 283, 8611-8623.