메뉴 건너뛰기




Volumn 195, Issue 1, 2014, Pages 23-29

Schistosomiasis control: Praziquantel forever?

Author keywords

Drugs; Mechanism of action; Oxamniquine; Praziquantel; Resistance; Schistosomiasis

Indexed keywords

ANTIMALARIAL AGENT; FURAZOLIDONE; MOLLUSCACIDE; OXAMNIQUINE; PRAZIQUANTEL; SCHISTOSOMA VACCINE; ANTISCHISTOSOMAL AGENT;

EID: 84904080868     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2014.06.002     Document Type: Review
Times cited : (311)

References (69)
  • 1
    • 0036086219 scopus 로고    scopus 로고
    • The paleoepidemiology of schistosomiasis in ancient Egypt
    • H. Kloos, and R. David The Paleoepidemiology of Schistosomiasis in Ancient Egypt Human Ecol Rev 9 2002 14 25 (Pubitemid 34657591)
    • (2002) Human Ecology Review , vol.9 , Issue.1 , pp. 14-25
    • Kloos, H.1    David, R.2
  • 2
    • 0034706868 scopus 로고    scopus 로고
    • The global status of schistosomiasis and its control
    • L. Chitsulo, D. Engels, A. Montresor, and L. Savioli The global status of schistosomiasis and its control Acta Trop 77 2000 41 51
    • (2000) Acta Trop , vol.77 , pp. 41-51
    • Chitsulo, L.1    Engels, D.2    Montresor, A.3    Savioli, L.4
  • 3
    • 33745436655 scopus 로고    scopus 로고
    • Schistosomiasis and water resources development: Systematic review, meta-analysis, and estimates of people at risk
    • DOI 10.1016/S1473-3099(06)70521-7, PII S1473309906705217
    • P. Steinmann, J. Keiser, R. Bos, M. Tanner, and J. Utzinger Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk Lancet Infect Dis 6 2006 411 425 (Pubitemid 43949139)
    • (2006) Lancet Infectious Diseases , vol.6 , Issue.7 , pp. 411-425
    • Steinmann, P.1    Keiser, J.2    Bos, R.3    Tanner, M.4    Utzinger, J.5
  • 5
    • 18144419337 scopus 로고    scopus 로고
    • Reassessment of the cost of chronic helmintic infection: A meta-analysis of disability-related outcomes in endemic schistosomiasis
    • DOI 10.1016/S0140-6736(05)66457-4
    • C.H. King, K. Dickman, and D.J. Tisch Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis Lancet 365 2005 1561 1569 (Pubitemid 40615405)
    • (2005) Lancet , vol.365 , Issue.9470 , pp. 1561-1569
    • King, C.H.1    Dickman, K.2    Tisch, D.J.3
  • 6
    • 0028991908 scopus 로고
    • Not by drugs alone: The fight against parasitic helminths
    • A.C. Evans, and L.S. Stephenson Not by drugs alone: the fight against parasitic helminths World Health Forum 16 1995 258 261 (Pubitemid 26465938)
    • (1995) World Health Forum , vol.16 , Issue.3 , pp. 258-261
    • Evans, A.C.1    Stephenson, L.S.2
  • 7
    • 0031470187 scopus 로고    scopus 로고
    • From discovery to eradication of Schistosomiasis in Japan: 1847-1996
    • DOI 10.1016/S0020-7519(97)00183-5, PII S0020751997001835
    • H. Tanaka, and M. Tsuji From discovery to eradication of schistosomiasis in Japan: 1847-1996 Int J Parasitol 27 1997 1465 1480 (Pubitemid 28026755)
    • (1997) International Journal for Parasitology , vol.27 , Issue.12 , pp. 1465-1480
    • Tanaka, H.1    Tsuji, M.2
  • 9
    • 33846462491 scopus 로고    scopus 로고
    • Schistosome vaccines: A critical appraisal
    • R.A. Wilson, and P.S. Coulson Schistosome vaccines: a critical appraisal Mem Inst Oswaldo Cruz 101 Suppl 1 2006 13 20 (Pubitemid 46143567)
    • (2006) Memorias do Instituto Oswaldo Cruz , vol.101 , Issue.SUPPL. 1 , pp. 13-20
    • Wilson, R.A.1    Coulson, P.S.2
  • 11
    • 0035236636 scopus 로고    scopus 로고
    • Schistosomiasis Epidemiology and Control: How Did We Get Here and Where Should We Go?
    • R.F. Sturrock Schistosomiasis epidemiology and control: how did we get here and where should we go? Mem Inst Oswaldo Cruz 96 Suppl. 2001 17 27 (Pubitemid 33639547)
    • (2001) Memorias do Instituto Oswaldo Cruz , vol.96 , Issue.SUPPL. , pp. 17-27
    • Sturrock, R.F.1
  • 12
    • 34848817366 scopus 로고    scopus 로고
    • Community acceptability of the use of low-dose niclosamide (Bayluscide®), as a molluscicide in the control of human schistosomiasis in Sahelian Cameroon
    • DOI 10.1179/136485907X193833
    • I. Takougang, J. Meli, and J. Wabo Poné Angwafo F 3rd. Community acceptability of the use of low-dose niclosamide (Bayluscide), as a molluscicide in the control of human schistosomiasis in Sahelian Cameroon Ann Trop Med Parasitol 101 2007 479 486 (Pubitemid 47489756)
    • (2007) Annals of Tropical Medicine and Parasitology , vol.101 , Issue.6 , pp. 479-486
    • Takougang, I.1    Meli, J.2    Pone, J.W.3    Angwafo III, F.4
  • 14
    • 84893018921 scopus 로고    scopus 로고
    • Regulation of laboratory populations of snails (Biomphalaria and Bulinus spp.) by river prawns, Macrobrachium spp. (Decapoda Palaemonidae): Implications for control of schistosomiasis
    • S.H. Sokolow, K.D. Lafferty, and A.M. Kuris Regulation of laboratory populations of snails (Biomphalaria and Bulinus spp.) by river prawns, Macrobrachium spp. (Decapoda Palaemonidae): implications for control of schistosomiasis Acta Trop 132 2014 64 74
    • (2014) Acta Trop , vol.132 , pp. 64-74
    • Sokolow, S.H.1    Lafferty, K.D.2    Kuris, A.M.3
  • 15
    • 0028895250 scopus 로고
    • Antischistosomal drugs: Past, present ... and future?
    • D. Cioli, L. Pica-Mattoccia, and S. Archer Antischistosomal drugs: past, present... and future? Pharmacol Ther 68 1995 35 85
    • (1995) Pharmacol Ther , vol.68 , pp. 35-85
    • Cioli, D.1    Pica-Mattoccia, L.2    Archer, S.3
  • 19
    • 0031741565 scopus 로고    scopus 로고
    • Is schistosomicidal chemotherapy sub-curative? Implications for drug resistance
    • DOI 10.1016/S0169-4758(98)01315-5, PII S0169475898013155
    • M.J. Doenhoff Is schistosomicidal chemotherapy sub-curative? Implications for drug resistance Parasitol Today 14 1998 434 435 (Pubitemid 28511208)
    • (1998) Parasitology Today , vol.14 , Issue.10 , pp. 434-435
    • Doenhoff, M.J.1
  • 20
    • 84883154375 scopus 로고    scopus 로고
    • Comparaison de l'efficacité thérapeutique et de la tolérance du praziquantel administré en prise unique à la dose de 40 versus 60 mg/kg pour le traitement de la bilharziose urinaire en Mauritanie
    • M. Ouldabdallahi, B. Ousmane, M. Ouldbezeid, D. Mamadou, L. Konaté, and L. Chitsulo Comparaison de l'efficacité thérapeutique et de la tolérance du praziquantel administré en prise unique à la dose de 40 versus 60 mg/kg pour le traitement de la bilharziose urinaire en Mauritanie Bull Soc Pathol Exot 106 2013 167 169
    • (2013) Bull Soc Pathol Exot , vol.106 , pp. 167-169
    • Ouldabdallahi, M.1    Ousmane, B.2    Ouldbezeid, M.3    Mamadou, D.4    Konaté, L.5    Chitsulo, L.6
  • 21
    • 0017622884 scopus 로고
    • A new broad-spectrum antischistosomal agent
    • R. Gönnert, P. Andrews, and Praziquantel a new broad-spectrum antischistosomal agent Z Parasitenkd 52 1977 129 150
    • (1977) Z Parasitenkd , vol.52 , pp. 129-150
    • Gönnert, R.1    Andrews, P.2    Praziquantel3
  • 22
    • 0022454720 scopus 로고
    • Schistosoma mansoni: Chemotherapy of infections of different ages
    • DOI 10.1016/0014-4894(86)90184-0
    • A.A. Sabah, C. Fletcher, G. Webbe, and M.J. Doenhoff Schistosoma mansoni: chemotherapy of infections of different ages Exp Parasitol 61 1986 294 303 (Pubitemid 16069841)
    • (1986) Experimental Parasitology , vol.61 , Issue.3 , pp. 294-303
    • Sabah, A.A.1    Fletcher, C.2    Webbe, G.3    Doenhoff, M.J.4
  • 23
    • 1542358686 scopus 로고    scopus 로고
    • Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment
    • DOI 10.1016/j.ijpara.2003.12.003, PII S0020751903003643
    • L. Pica-Mattoccia, and D. Cioli Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment Int J Parasitol 34 2004 527 533 (Pubitemid 38317176)
    • (2004) International Journal for Parasitology , vol.34 , Issue.4 , pp. 527-533
    • Pica-Mattoccia, L.1    Cioli, D.2
  • 24
    • 0029075955 scopus 로고
    • Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni
    • F.F. Stelma, I. Talla, S. Sow, A. Kongs, M. Niang, and K. Polman et al. Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni Am J Trop Med Hyg 53 1995 167 170
    • (1995) Am J Trop Med Hyg , vol.53 , pp. 167-170
    • Stelma, F.F.1    Talla, I.2    Sow, S.3    Kongs, A.4    Niang, M.5    Polman, K.6
  • 25
    • 0031741442 scopus 로고    scopus 로고
    • An international initiative on praziquantel use
    • DOI 10.1016/S0169-4758(98)01310-6, PII S0169475898013106
    • E. Renganathan, and D. Cioli An international initiative on praziquantel use Parasitol Today 14 1998 390 391 (Pubitemid 28511198)
    • (1998) Parasitology Today , vol.14 , Issue.10 , pp. 390-391
    • Renganathan, E.1    Cioli, D.2
  • 26
    • 0034533379 scopus 로고    scopus 로고
    • Efficacy of praziquantel against Schistosoma mansoni with particular consideration for intensity of infection
    • DOI 10.1046/j.1365-3156.2000.00646.x
    • J. Utzinger, E.K. N'Goran, A. N'Dri, C. Lengeler, and M. Tanner Efficacy of praziquantel against Schistosoma mansoni with particular consideration for intensity of infection Trop Med Int Health 5 2000 771 778 (Pubitemid 32001036)
    • (2000) Tropical Medicine and International Health , vol.5 , Issue.11 , pp. 771-778
    • Utzinger, J.1    N'Goran, E.K.2    N'Dri, A.3    Lengeler, C.4    Tanner, M.5
  • 27
    • 0026044845 scopus 로고
    • Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of schistosomiasis japonica
    • M.H. Wu, C.C. Wei, Z.Y. Xu, H.C. Yuan, W.N. Lian, and Q.J. Yang et al. Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of schistosomiasis japonica Am J Trop Med Hyg 45 1991 345 349
    • (1991) Am J Trop Med Hyg , vol.45 , pp. 345-349
    • Wu, M.H.1    Wei, C.C.2    Xu, Z.Y.3    Yuan, H.C.4    Lian, W.N.5    Yang, Q.J.6
  • 28
    • 65549111256 scopus 로고    scopus 로고
    • Taste a new incentive to switch to (R)-praziquantel in schistosomiasis treatment
    • 10.1371/journal.pntd.0000357
    • T. Meyer, H. Sekljic, S. Fuchs, H. Bothe, D. Schollmeyer, and C. Miculka Taste a new incentive to switch to (R)-praziquantel in schistosomiasis treatment PLoS Negl Trop Dis 3 2009 e357 10.1371/journal.pntd.0000357
    • (2009) PLoS Negl Trop Dis , vol.3 , pp. 357
    • Meyer, T.1    Sekljic, H.2    Fuchs, S.3    Bothe, H.4    Schollmeyer, D.5    Miculka, C.6
  • 30
    • 84879120970 scopus 로고    scopus 로고
    • Praziquantel treatment in trematode and cestode infections: An update
    • J.Y. Chai Praziquantel treatment in trematode and cestode infections: an update Infect Chemother 45 2013 32 43
    • (2013) Infect Chemother , vol.45 , pp. 32-43
    • Chai, J.Y.1
  • 31
    • 84878406090 scopus 로고    scopus 로고
    • Application of praziquantel in schistosomiasis japonica control strategies in China
    • W. Wu, and Y. Huang Application of praziquantel in schistosomiasis japonica control strategies in China Parasitol Res 112 2013 909 915
    • (2013) Parasitol Res , vol.112 , pp. 909-915
    • Wu, W.1    Huang, Y.2
  • 32
    • 84872032993 scopus 로고    scopus 로고
    • Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. Haematobium
    • J.T. Coulibaly, Y.K. N'gbesso, S. Knopp, J. Keiser, E.K. N'Goran, and J. Utzinger Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium PLoS Negl Trop Dis 6 2012 e1917
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. 1917
    • Coulibaly, J.T.1    N'Gbesso, Y.K.2    Knopp, S.3    Keiser, J.4    N'Goran, E.K.5    Utzinger, J.6
  • 35
    • 79953274566 scopus 로고    scopus 로고
    • A paragonimiasis patient with allergic reaction to praziquantel and resistance to triclabendazole: Successful treatment after desensitization to praziquantel
    • S.Y. Kyung, Y.K. Cho, Y.J. Kim, J.W. Park, S.H. Jeong, and J.I. Lee et al. A paragonimiasis patient with allergic reaction to praziquantel and resistance to triclabendazole: successful treatment after desensitization to praziquantel Korean J Parasitol 49 2011 73 77
    • (2011) Korean J Parasitol , vol.49 , pp. 73-77
    • Kyung, S.Y.1    Cho, Y.K.2    Kim, Y.J.3    Park, J.W.4    Jeong, S.H.5    Lee, J.I.6
  • 39
    • 0035263776 scopus 로고    scopus 로고
    • Refugia - Overlooked as perhaps the most potent factor concerning the development of anthelmintic resistance
    • J.A. van Wyk Refugia - overlooked as perhaps the most potent factor concerning the development of anthelmintic resistance Onderstepoort J Vet Res 68 2001 55 67 (Pubitemid 33405766)
    • (2001) Onderstepoort Journal of Veterinary Research , vol.68 , Issue.1 , pp. 55-67
    • Van Wyk, J.A.1
  • 41
    • 19544373146 scopus 로고    scopus 로고
    • Current status of sensitivity to praziquantel in a focus of potential drug resistance in Egypt
    • DOI 10.1016/j.ijpara.2005.02.005, PII S0020751905000457, Annual Scientific Meeting of the Australian Society for Parasitology, Freemantle Esplanade Hotel, 2004 Highlights
    • S. Botros, H. Sayed, N. Amer, M. El-Ghannam, J.L. Bennett, and T.A. Day Current status of sensitivity to praziquantel in a focus of potential drug resistance in Egypt Int J Parasitol 35 2005 787 791 (Pubitemid 40733617)
    • (2005) International Journal for Parasitology , vol.35 , Issue.7 , pp. 787-791
    • Botros, S.1    Sayed, H.2    Amer, N.3    El-Ghannam, M.4    Bennett, J.L.5    Day, T.A.6
  • 42
    • 77950666160 scopus 로고    scopus 로고
    • Praziquantel efficacy and long-term appraisal of schistosomiasis control in Pemba Island
    • May
    • A. Guidi, C. Andolina, S. Makame Ame, M. Albonico, D. Cioli, and H. Juma Haji Praziquantel efficacy and long-term appraisal of schistosomiasis control in Pemba Island Trop Med Int Health 15 May (5) 2010 614 618
    • (2010) Trop Med Int Health , vol.15 , Issue.5 , pp. 614-618
    • Guidi, A.1    Andolina, C.2    Makame Ame, S.3    Albonico, M.4    Cioli, D.5    Juma Haji, H.6
  • 43
    • 0022340205 scopus 로고
    • Schistosoma mansoni: Reduced efficacy chemotherapy in infected T-cell-deprived mice
    • DOI 10.1016/0014-4894(85)90041-4
    • A.A. Sabah, C. Fletcher, G. Webbe, and M.J. Doenhoff Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice Exp Parasitol 60 1985 348 354 (Pubitemid 16178911)
    • (1985) Experimental Parasitology , vol.60 , Issue.3 , pp. 348-354
    • Sabah, A.A.1    Fletcher, C.2    Webbe, G.3    Doenhoff, M.J.4
  • 45
    • 0028025029 scopus 로고
    • Drug-resistant schistosomiasis: Resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific
    • P.G. Fallon, and M.J. Doenhoff Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific Am J Trop Med Hyg 51 1994 83 88 (Pubitemid 24266292)
    • (1994) American Journal of Tropical Medicine and Hygiene , vol.51 , Issue.1 , pp. 83-88
    • Fallon, P.G.1    Doenhoff, M.J.2
  • 46
    • 67349259362 scopus 로고    scopus 로고
    • Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni
    • L. Pica-Mattoccia, M.J. Doenhoff, C. Valle, A. Basso, A.R. Troiani, and P. Liberti et al. Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni Acta Trop 111 2009 82 85
    • (2009) Acta Trop , vol.111 , pp. 82-85
    • Pica-Mattoccia, L.1    Doenhoff, M.J.2    Valle, C.3    Basso, A.4    Troiani, A.R.5    Liberti, P.6
  • 47
    • 79955389741 scopus 로고    scopus 로고
    • Schistosoma mansoni: A method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails
    • F.F. Couto, P.M. Coelho, N. Araújo, J.R. Kusel, N. Katz, and L.K. Jannotti-Passos et al. Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails Mem Inst Oswaldo Cruz 106 2011 153 157
    • (2011) Mem Inst Oswaldo Cruz , vol.106 , pp. 153-157
    • Couto, F.F.1    Coelho, P.M.2    Araújo, N.3    Kusel, J.R.4    Katz, N.5    Jannotti-Passos, L.K.6
  • 48
    • 21644469993 scopus 로고    scopus 로고
    • 2+ channels targets of praziquantel action?
    • DOI 10.1016/j.ijpara.2004.09.004
    • 2+ channels targets of praziquantel action? Int J Parasitol 35 2005 1 9 (Pubitemid 41556666)
    • (2005) International Journal for Parasitology , vol.35 , Issue.1 , pp. 1-9
    • Greenberg, R.M.1
  • 52
    • 44249113542 scopus 로고    scopus 로고
    • Schistosoma mansoni: Lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death
    • L. Pica-Mattoccia, T. Orsini, A. Basso, A. Festucci, P. Liberti, and A. Guidi et al. Schistosoma mansoni: lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death Exp Parasitol 119 2008 332 335
    • (2008) Exp Parasitol , vol.119 , pp. 332-335
    • Pica-Mattoccia, L.1    Orsini, T.2    Basso, A.3    Festucci, A.4    Liberti, P.5    Guidi, A.6
  • 57
    • 0027137044 scopus 로고
    • Schistosoma mansoni: Genetic complementation analysis shows that two independent hycanthone/oxamniquine-resistant strains are mutated in the same gene
    • L. Pica-Mattoccia, L.C. Dias, R. Moroni, and D. Cioli Schistosoma mansoni: genetic complementation analysis shows that two independent hycanthone/oxamniquine-resistant strains are mutated in the same gene Exp Parasitol 77 1993 445 449
    • (1993) Exp Parasitol , vol.77 , pp. 445-449
    • Pica-Mattoccia, L.1    Dias, L.C.2    Moroni, R.3    Cioli, D.4
  • 58
    • 79960275332 scopus 로고    scopus 로고
    • Current and future antischistosomal drugs
    • W.E. Secor, D.G. Colley, Springer New York
    • D. Cioli, and L. Pica-Mattoccia Current and future antischistosomal drugs W.E. Secor, D.G. Colley, Schistosomiasis, world class parasites series vol. 10 2005 Springer New York 191 206
    • (2005) Schistosomiasis, World Class Parasites Series , vol.10 , pp. 191-206
    • Cioli, D.1    Pica-Mattoccia, L.2
  • 60
    • 84890114435 scopus 로고    scopus 로고
    • Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites
    • C.L. Valentim, D. Cioli, F.D. Chevalier, X. Cao, A.B. Taylor, and S.P. Holloway et al. Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites Science 342 2013 1385 1389
    • (2013) Science , vol.342 , pp. 1385-1389
    • Valentim, C.L.1    Cioli, D.2    Chevalier, F.D.3    Cao, X.4    Taylor, A.B.5    Holloway, S.P.6
  • 61
    • 84866675899 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of artemisinin based therapies for the treatment and prevention of schistosomiasis
    • L. Pérez del Villar, F.J. Burguillo, J. López-Abán, and A. Muro Systematic review and meta-analysis of artemisinin based therapies for the treatment and prevention of schistosomiasis PLoS ONE 7 2012 e45867
    • (2012) PLoS ONE , vol.7 , pp. 45867
    • Pérez Del Villar, L.1    Burguillo, F.J.2    López-Abán, J.3    Muro, A.4
  • 64
    • 0037197711 scopus 로고    scopus 로고
    • The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase
    • DOI 10.1016/S0166-6851(02)00031-2, PII S0166685102000312
    • H.M. Alger, and D.L. Williams The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase Mol Biochem Parasitol 121 2002 129 139 (Pubitemid 34457840)
    • (2002) Molecular and Biochemical Parasitology , vol.121 , Issue.1 , pp. 129-139
    • Alger, H.M.1    Williams, D.L.2
  • 65
    • 77957793022 scopus 로고    scopus 로고
    • Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography
    • F. Angelucci, D. Dimastrogiovanni, G. Boumis, M. Brunori, A.E. Miele, and F. Saccoccia et al. Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography J Biol Chem 285 2010 32557 32567
    • (2010) J Biol Chem , vol.285 , pp. 32557-32567
    • Angelucci, F.1    Dimastrogiovanni, D.2    Boumis, G.3    Brunori, M.4    Miele, A.E.5    Saccoccia, F.6
  • 66
    • 41849098521 scopus 로고    scopus 로고
    • Identification of oxadiazoles as new drug leads for the control of schistosomiasis
    • DOI 10.1038/nm1737, PII NM1737
    • A.A. Sayed, A. Simeonov, C.J. Thomas, J. Inglese, C.P. Austin, and D.L. Williams Identification of oxadiazoles as new drug leads for the control of schistosomiasis Nat Med 14 2008 407 412 (Pubitemid 351499390)
    • (2008) Nature Medicine , vol.14 , Issue.4 , pp. 407-412
    • Sayed, A.A.1    Simeonov, A.2    Thomas, C.J.3    Inglese, J.4    Austin, C.P.5    Williams, D.L.6
  • 68
    • 84876005735 scopus 로고    scopus 로고
    • Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII
    • H. You, D.P. McManus, W. Hu, M.J. Smout, P.J. Brindley, and G.N. Gobert Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII PLoS Pathog 9 2013 e1003254
    • (2013) PLoS Pathog , vol.9 , pp. 1003254
    • You, H.1    McManus, D.P.2    Hu, W.3    Smout, M.J.4    Brindley, P.J.5    Gobert, G.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.