Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII

PLoS Pathogens

Volumn 9, Issue 3, 2013, Pages

  You, Hong ^a   McManus, Donald P ^a   Hu, Wei ^b   Smout, Michael J ^c   Brindley, Paul J ^d   Gobert, Geoffrey N ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b FUDAN UNIVERSITY   (China)

^c JAMES COOK UNIVERSITY   (Australia)

^d GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; PRAZIQUANTEL;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ASSAY; CONTROLLED STUDY; DEFENSE MECHANISM; DRUG DETOXIFICATION; DRUG EXPOSURE; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; IC 50; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA ISOLATION; SCHISTOSOMA JAPONICUM; UPREGULATION; VALIDATION PROCESS;

ANIMALS; ANTHELMINTICS; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DISEASE MODELS, ANIMAL; DRUG RESISTANCE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GENOME, HELMINTH; GENOME-WIDE ASSOCIATION STUDY; INHIBITORY CONCENTRATION 50; MALE; MICE; MICE, INBRED BALB C; PRAZIQUANTEL; RNA, SMALL INTERFERING; SCHISTOSOMA JAPONICUM; SEX FACTORS;

MUS; SCHISTOSOMA JAPONICUM;

EID: 84876005735     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003254     Document Type: Article

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