-
1
-
-
0037129443
-
Schistosomiasis
-
(DOI: 10.1056/NEJMra012396)
-
Ross AGP, Bartley PB, Sleigh AC, Olds GR, Li Y, et al. (2002) Schistosomiasis. N Engl J Med 346: 1212-1220 (DOI: 10.1056/NEJMra012396).
-
(2002)
N Engl J Med
, vol.346
, pp. 1212-1220
-
-
Ross, A.G.P.1
Bartley, P.B.2
Sleigh, A.C.3
Olds, G.R.4
Li, Y.5
-
2
-
-
0034706868
-
The global status of schistosomiasis and its control
-
(DOI: 10.1016/S0001-706X(00)00122-4)
-
Chitsulo L, Engels D, Montresor A, Savioli L, (2000) The global status of schistosomiasis and its control. Acta Trop 77: 41-51 (DOI: 10.1016/S0001-706X(00)00122-4).
-
(2000)
Acta Trop
, vol.77
, pp. 41-51
-
-
Chitsulo, L.1
Engels, D.2
Montresor, A.3
Savioli, L.4
-
3
-
-
18144419337
-
Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis
-
(DOI: 10.1016/S0140-6736(05)66457-4)
-
King CH, Dickman K, Tisch DJ, (2005) Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis. Lancet 365: 1561-1569 (DOI: 10.1016/S0140-6736(05)66457-4).
-
(2005)
Lancet
, vol.365
, pp. 1561-1569
-
-
King, C.H.1
Dickman, K.2
Tisch, D.J.3
-
4
-
-
34548126499
-
Chemotherapy of schistosomiasis: present and future
-
(DOI: 10.1016/j.cbpa.2007.05.031)
-
Caffrey CR, (2007) Chemotherapy of schistosomiasis: present and future. Curr Opin Chem Biol 11: 433-439 (DOI: 10.1016/j.cbpa.2007.05.031).
-
(2007)
Curr Opin Chem Biol
, vol.11
, pp. 433-439
-
-
Caffrey, C.R.1
-
5
-
-
80053452934
-
Chemotherapeutic development strategies for schistosomiasis
-
In: Selzer PM, editors, Weinheim, Germany, Wiley-VCH Verlag GmbH & Co. KGaA, (DOI: 10.1002/9783527626816.ch16)
-
Caffrey CR, Williams DL, Todd MH, Nelson DL, Keiser J, et al. (2009) Chemotherapeutic development strategies for schistosomiasis. In: Selzer PM, editors. Antiparasitic and antibacterial drug discovery from molecular targets to drug candidates Weinheim, Germany Wiley-VCH Verlag GmbH & Co. KGaA (DOI: 10.1002/9783527626816.ch16).
-
(2009)
Antiparasitic and Antibacterial Drug Discovery from Molecular Targets to Drug Candidates
-
-
Caffrey, C.R.1
Williams, D.L.2
Todd, M.H.3
Nelson, D.L.4
Keiser, J.5
-
6
-
-
0142227135
-
Drugs for the control of parasitic diseases: current status and development
-
(DOI: 10.1016/j.pt.2003.09.005)
-
Fenwick A, Savioli L, Engels D, Bergquist R, Todd MH, (2003) Drugs for the control of parasitic diseases: current status and development. Schistosomiasis Trends Parasitol 19: 509-515 (DOI: 10.1016/j.pt.2003.09.005).
-
(2003)
Schistosomiasis Trends Parasitol
, vol.19
, pp. 509-515
-
-
Fenwick, A.1
Savioli, L.2
Engels, D.3
Bergquist, R.4
Todd, M.H.5
-
7
-
-
0020525864
-
Praziquantel
-
(DOI: 10.1002/med.2610030204)
-
Andrews P, Thomas H, Pohlke R, Seubert J, (1983) Praziquantel. Med Res Rev 3: 147-200 (DOI: 10.1002/med.2610030204).
-
(1983)
Med Res Rev
, vol.3
, pp. 147-200
-
-
Andrews, P.1
Thomas, H.2
Pohlke, R.3
Seubert, J.4
-
8
-
-
57049129327
-
Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis
-
(DOI: 10.1097/QCO.0b013e328318978f)
-
Doenhoff MJ, Cioli D, Utzinger J, (2008) Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Curr Opin Infect Dis 21: 659-667 (DOI: 10.1097/QCO.0b013e328318978f).
-
(2008)
Curr Opin Infect Dis
, vol.21
, pp. 659-667
-
-
Doenhoff, M.J.1
Cioli, D.2
Utzinger, J.3
-
9
-
-
84881229401
-
Schistosomiasis Control Initiative Website
-
Available:. Accessed 2011 Jun 27
-
Schistosomiasis Control Initiative Website. Available: http://www3.imperial.ac.uk/schisto. Accessed 2011 Jun 27.
-
-
-
-
10
-
-
77956035611
-
Africa is desperate for praziquantel
-
(DOI: 10.1016/S0140-6736(10)60879-3)
-
Hotez PJ, Engels D, Fenwick A, Savioli L, (2010) Africa is desperate for praziquantel. Lancet 376: 496-498 (DOI: 10.1016/S0140-6736(10)60879-3).
-
(2010)
Lancet
, vol.376
, pp. 496-498
-
-
Hotez, P.J.1
Engels, D.2
Fenwick, A.3
Savioli, L.4
-
11
-
-
0028025029
-
Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific
-
Fallon PG, Doenhoff MJ, (1994) Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. Am J Trop Med Hyg51: 83-88 (http://www.ajtmh.org/cgi/content/abstract/51/1/83).
-
(1994)
Am J Trop Med Hyg
, vol.51
, pp. 83-88
-
-
Fallon, P.G.1
Doenhoff, M.J.2
-
12
-
-
77954714023
-
Susceptibility to praziquantel of male and female cercariae of praziquantel-resistant and susceptible isolates of Schistosoma mansoni
-
(DOI: 10.1017/S0022149X0999054X)
-
Liang YS, Wang W, Dai JR, Li HJ, Tao YH, et al. (2010) Susceptibility to praziquantel of male and female cercariae of praziquantel-resistant and susceptible isolates of Schistosoma mansoni. J Helminthol 84: 202-207 (DOI: 10.1017/S0022149X0999054X).
-
(2010)
J Helminthol
, vol.84
, pp. 202-207
-
-
Liang, Y.S.1
Wang, W.2
Dai, J.R.3
Li, H.J.4
Tao, Y.H.5
-
13
-
-
70449510166
-
Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni
-
(DOI: 10.1371/journal.pntd.0000504)
-
Melman SD, Steinauer ML, Cunningham C, Kubatko LS, Mwangi IN, et al. (2009) Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni. PLoS Neglect Trop D 3: e504 (DOI: 10.1371/journal.pntd.0000504).
-
(2009)
PLoS Neglect Trop D
, vol.3
-
-
Melman, S.D.1
Steinauer, M.L.2
Cunningham, C.3
Kubatko, L.S.4
Mwangi, I.N.5
-
14
-
-
0036758608
-
Resistance of Schistosoma mansoni to praziquantel: is there a problem?
-
(DOI: 10.1016/S0035-9203(02)90405-0)
-
Doenhoff MJ, Kusel JR, Coles GC, Cioli D, (2002) Resistance of Schistosoma mansoni to praziquantel: is there a problem? T Roy Soc Trop Med H 96: 465-469 (DOI: 10.1016/S0035-9203(02)90405-0).
-
(2002)
T Roy Soc Trop Med H
, vol.96
, pp. 465-469
-
-
Doenhoff, M.J.1
Kusel, J.R.2
Coles, G.C.3
Cioli, D.4
-
15
-
-
0034892861
-
In vitro responses of praziquantel-resistant and -susceptible Schistosoma mansoni to praziquantel
-
(DOI: 10.1016/S0020-7519(01)00246-6)
-
Liang YS, Coles GC, Doenhoff MJ, Southgate VR, (2001) In vitro responses of praziquantel-resistant and-susceptible Schistosoma mansoni to praziquantel. Int J Parasitol 31: 1227-1235 (DOI: 10.1016/S0020-7519(01)00246-6).
-
(2001)
Int J Parasitol
, vol.31
, pp. 1227-1235
-
-
Liang, Y.S.1
Coles, G.C.2
Doenhoff, M.J.3
Southgate, V.R.4
-
16
-
-
77950267287
-
Praziquantel analogs with activity against juvenile Schistosoma mansoni
-
(DOI: 10.1016/j.bmcl.2010.03.001)
-
Dong Y, Chollet J, Vargas M, Mansour NR, Bickle B, et al. (2010) Praziquantel analogs with activity against juvenile Schistosoma mansoni. Bioorg Med Chem Lett 20: 2481-2484 (DOI: 10.1016/j.bmcl.2010.03.001).
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 2481-2484
-
-
Dong, Y.1
Chollet, J.2
Vargas, M.3
Mansour, N.R.4
Bickle, B.5
-
17
-
-
53649101019
-
Synthesis of "trioxaquantel"® derivatives as potential new antischistosomal drugs
-
DOI: 10.1002/ejoc.200700975
-
Laurent SAL, Boissier J, Coslédan F, Gornitzka H, Robert A, et al. (2008) Synthesis of "trioxaquantel"® derivatives as potential new antischistosomal drugs. Eur J Org Chem 895-913 (DOI: 10.1002/ejoc.200700975).
-
(2008)
Eur J Org Chem
, pp. 895-913
-
-
Laurent, S.A.L.1
Boissier, J.2
Coslédan, F.3
Gornitzka, H.4
Robert, A.5
-
18
-
-
34347387279
-
Praziquantel analogues. I. Modification of the aromatic ring
-
(DOI: 10.1016/j.bmcl.2007.05.063)
-
Ronketti FE, Ramana AV, Chao-Ming X, Pica-Mattoccia L, Cioli D, et al. (2007) Praziquantel analogues. I. Modification of the aromatic ring. Bioorg Med Chem Lett 17: 4154-4157 (DOI: 10.1016/j.bmcl.2007.05.063).
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 4154-4157
-
-
Ronketti, F.E.1
Ramana, A.V.2
Chao-Ming, X.3
Pica-Mattoccia, L.4
Cioli, D.5
-
19
-
-
41849098521
-
Identification of oxadiazoles as new drug leads for the control of schistosomiasis
-
(DOI: 10.1038/nm1737)
-
Sayed AA, Simeonov A, Thomas CJ, Inglese J, Austin CP, (2008) Identification of oxadiazoles as new drug leads for the control of schistosomiasis. Nat Med 14: 407-412 (DOI: 10.1038/nm1737).
-
(2008)
Nat Med
, vol.14
, pp. 407-412
-
-
Sayed, A.A.1
Simeonov, A.2
Thomas, C.J.3
Inglese, J.4
Austin, C.P.5
-
20
-
-
48949117601
-
Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade
-
(DOI: 10.1371/journal.pntd.0000127)
-
Simeonov A, Jadhav A, Sayed AA, Wang Y, Nelson ME, et al. (2008) Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade. PLoS Negl Trop D 2 (1): e127 (DOI: 10.1371/journal.pntd.0000127).
-
(2008)
PLoS Negl Trop D
, vol.2
, Issue.1
-
-
Simeonov, A.1
Jadhav, A.2
Sayed, A.A.3
Wang, Y.4
Nelson, M.E.5
-
21
-
-
0024586454
-
Comparative in vitro and in vivo activity of racemic praziquantel and its levorotated isomer on Schistosoma mansoni
-
Xiao SH, Catto BA, (1989) Comparative in vitro and in vivo activity of racemic praziquantel and its levorotated isomer on Schistosoma mansoni. J Infect Dis 159: 589-592 (http://www.jstor.org/stable/30137494).
-
(1989)
J Infect Dis
, vol.159
, pp. 589-592
-
-
Xiao, S.H.1
Catto, B.A.2
-
22
-
-
0026044845
-
Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of Schistosomiasis japonica.
-
Wu MH, Wei CC, Xu ZY, Yuan HC, Lian WN, et al. (1991) Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of Schistosomiasis japonica. Am J Trop Med Hyg45: 345-349 (http://www.ajtmh.org/cgi/content/abstract/45/3/345).
-
(1991)
Am J Trop Med Hyg
, vol.45
, pp. 345-349
-
-
Wu, M.H.1
Wei, C.C.2
Xu, Z.Y.3
Yuan, H.C.4
Lian, W.N.5
-
23
-
-
0022884546
-
Comparative efficacy of praziquantel and its optic isomers in experimental therapy of Schistosomiasis japonica in rabbits
-
Liu Y, Qian M, Wang X, Jia J, Wang Q, et al. (1986) Comparative efficacy of praziquantel and its optic isomers in experimental therapy of Schistosomiasis japonica in rabbits. Chin Medical J 99: 935-940.
-
(1986)
Chin Medical J
, vol.99
, pp. 935-940
-
-
Liu, Y.1
Qian, M.2
Wang, X.3
Jia, J.4
Wang, Q.5
-
24
-
-
0024412804
-
A comparison of the antischistosomal effect of levo- and dextro-praziquantel on Schistosoma japonicum and S. mansoni in mice
-
Tanaka M, Ohmae H, Utsunomiya H, Nara T, Irie Y, et al. (1989) A comparison of the antischistosomal effect of levo- and dextro-praziquantel on Schistosoma japonicum and S. mansoni in mice. Am J Trop Med Hyg41: 198-203.
-
(1989)
Am J Trop Med Hyg
, vol.41
, pp. 198-203
-
-
Tanaka, M.1
Ohmae, H.2
Utsunomiya, H.3
Nara, T.4
Irie, Y.5
-
25
-
-
65549111256
-
Taste, A new incentive to switch to (R)-praziquantel in schistosomiasis treatment
-
(DOI: 10.1371/journal.pntd.0000357)
-
Meyer T, Sekljic H, Fuchs S, Bothe H, Schollmeyer D, et al. (2009) Taste, A new incentive to switch to (R)-praziquantel in schistosomiasis treatment. PLoS Negl Trop D 3: e357 (DOI: 10.1371/journal.pntd.0000357).
-
(2009)
PLoS Negl Trop D
, vol.3
-
-
Meyer, T.1
Sekljic, H.2
Fuchs, S.3
Bothe, H.4
Schollmeyer, D.5
-
26
-
-
38349085904
-
Resisting control of neglected tropical diseases: dilemmas in the mass treatment of schistosomiasis and soil-transmitted helminths in north-west Uganda
-
(DOI: 10.1017/S0021932007002301)
-
Parker M, Allen T, Hastings J, (2008) Resisting control of neglected tropical diseases: dilemmas in the mass treatment of schistosomiasis and soil-transmitted helminths in north-west Uganda. J Biosoc Sci 40: 161-181 (DOI: 10.1017/S0021932007002301).
-
(2008)
J Biosoc Sci
, vol.40
, pp. 161-181
-
-
Parker, M.1
Allen, T.2
Hastings, J.3
-
27
-
-
75649129083
-
Process evaluation of schistosomiasis control in Uganda, 2003 to 2006: perceptions, attitudes and constraints of a national control programme
-
(DOI: 10.1017/S0031182009990709)
-
Fleming FM, Fenwick A, Tukahebwa EM, Lubanga RG, Namwangye H, et al. (2009) Process evaluation of schistosomiasis control in Uganda, 2003 to 2006: perceptions, attitudes and constraints of a national control programme. Parasitology 136: 1759-1769 (DOI: 10.1017/S0031182009990709).
-
(2009)
Parasitology
, vol.136
, pp. 1759-1769
-
-
Fleming, F.M.1
Fenwick, A.2
Tukahebwa, E.M.3
Lubanga, R.G.4
Namwangye, H.5
-
28
-
-
80053454531
-
Business Plan 2008-2013, WHO/TDR
-
Drug Development and Evaluation for Helminths and Other Neglected Tropical Diseases, Available:. Accessed 2011 Jun 27
-
Drug Development and Evaluation for Helminths and Other Neglected Tropical Diseases (2007) Business Plan 2008-2013, WHO/TDR. Available: http://apps.who.int/tdr/svc/publications/about-tdr/business-plans/bl6-business-plan-2008-2013. Accessed 2011 Jun 27.
-
(2007)
-
-
-
29
-
-
58549087709
-
Towards an understanding of the mechanism of action of praziquantel
-
and references cited therein. (DOI: 10.1016/j.molbiopara.2008.11.007)
-
Aragon AD, Imani RA, Blackburn VR, Cupit PM, Melman SD, et al. (2009) Towards an understanding of the mechanism of action of praziquantel. Mol Biochem Parasit 164: 57-65 and references cited therein. (DOI: 10.1016/j.molbiopara.2008.11.007).
-
(2009)
Mol Biochem Parasit
, vol.164
, pp. 57-65
-
-
Aragon, A.D.1
Imani, R.A.2
Blackburn, V.R.3
Cupit, P.M.4
Melman, S.D.5
-
30
-
-
33744984150
-
Enantioselective synthesis of (R)-(-)-praziquantel (PZQ)
-
(DOI: 10.1016/j.tetasy.2006.04.023)
-
Roszkowski P, Maurin JK, Czarnocki Z, (2006) Enantioselective synthesis of (R)-(-)-praziquantel (PZQ). Tetrahedron: Asymmetry 17: 1415-1419 (DOI: 10.1016/j.tetasy.2006.04.023).
-
(2006)
Tetrahedron: Asymmetry
, vol.17
, pp. 1415-1419
-
-
Roszkowski, P.1
Maurin, J.K.2
Czarnocki, Z.3
-
31
-
-
2942567749
-
Total synthesis of (-)-praziquantel: an anthelmintic drug
-
(DOI: 10.3184/0308234041640564)
-
Ma C, Zhang QF, Tan YB, Wang L, (2004) Total synthesis of (-)-praziquantel: an anthelmintic drug. J Chem Res pp. 186-187 (DOI: 10.3184/0308234041640564).
-
(2004)
J Chem Res
, pp. 186-187
-
-
Ma, C.1
Zhang, Q.F.2
Tan, Y.B.3
Wang, L.4
-
32
-
-
80053458075
-
Pyrazinoisoquinolines as anthelmintic agents
-
US Patent 3,993,760 (German patent (1973) 2,331,713)
-
Pohlke R, Loebich F, Seubert J, Thomas H, Andrews P, (1976) Pyrazinoisoquinolines as anthelmintic agents. US Patent 3,993,760 (German patent (1973) 2,331,713) (http://www.google.com/patents/about?id=qrs1AAAAEBAJdq=3993760).
-
(1976)
-
-
Pohlke, R.1
Loebich, F.2
Seubert, J.3
Thomas, H.4
Andrews, P.5
-
33
-
-
80053441585
-
Process for preparing (1-acylaminomethyl)-1,2,3,4-tetrahydroisoquinolines
-
US Patent 4,362,875 (German patent (1975) 2,504,250) ()
-
Seubert J, (1982) Process for preparing (1-acylaminomethyl)-1,2,3,4-tetrahydroisoquinolines. US Patent 4,362,875 (German patent (1975) 2,504,250) (http://www.google.com/patents/about?id=7EE4AAAAEBAJdq=4362875).
-
(1982)
-
-
Seubert, J.1
-
34
-
-
80053452663
-
Attempt at asymmetric hydrogenation of intermediate enamide: 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
-
US Patent 4,001,411 (German patent (1973) 2,362,539) ()
-
Seubert J, Thomas H, Andrews P, (1977) Attempt at asymmetric hydrogenation of intermediate enamide: 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof. US Patent 4,001,411 (German patent (1973) 2,362,539) (http://www.google.com/patents/about?id=xxEtAAAAEBAJdq=4001411).
-
(1977)
-
-
Seubert, J.1
Thomas, H.2
Andrews, P.3
-
35
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/276#comment-596. Accessed 2011 Jun 27.
-
-
-
-
36
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/315. Accessed 2011 Jun 27.
-
-
-
-
37
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/313#comment-540. Accessed 2011 Jun 27.
-
-
-
-
38
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/296. Accessed 2011 Jun 27.
-
-
-
-
39
-
-
0032565993
-
Formation of pyrazinoisoquinoline ring system by the tandem amidoalkylation and N-acyliminium ion cyclization: an efficient synthesis of praziquantel
-
(DOI: 10.1016/S0040-4020(98)00401-3)
-
Kim JH, Lee YS, Park H, Kim CS, (1998) Formation of pyrazinoisoquinoline ring system by the tandem amidoalkylation and N-acyliminium ion cyclization: an efficient synthesis of praziquantel. Tetrahedron 54: 7395-7400 (DOI: 10.1016/S0040-4020(98)00401-3).
-
(1998)
Tetrahedron
, vol.54
, pp. 7395-7400
-
-
Kim, J.H.1
Lee, Y.S.2
Park, H.3
Kim, C.S.4
-
40
-
-
80053438362
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/696. Accessed 2011 Jun 27.
-
-
-
-
41
-
-
80053436728
-
-
Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/717. Accessed 2011 Jun 27.
-
-
-
-
42
-
-
80053452527
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/742. Accessed 2011 Jun 27.
-
-
-
-
43
-
-
80053451085
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/1279. Accessed 2011 Jun 27.
-
-
-
-
44
-
-
15044362464
-
Convenient and inexpensive synthesis of (1R,2R)-trans-1-amino-6-nitroindan-2-ol
-
(DOI: 10.1002/adsc.200404296)
-
Kozhushkov SI, Yufit DS, de Meijere A, (2005) Convenient and inexpensive synthesis of (1R,2R)-trans-1-amino-6-nitroindan-2-ol. Adv Synth Catal 347: 255-265 (DOI: 10.1002/adsc.200404296).
-
(2005)
Adv Synth Catal
, vol.347
, pp. 255-265
-
-
Kozhushkov, S.I.1
Yufit, D.S.2
de Meijere, A.3
-
45
-
-
80053445711
-
Novel processes for the preparation or (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
-
US Patent Application US 2002/0151717 (A1)
-
Daugs ED, Evans JC, Flemming HW, Hilpert THE, Koek JN, et al. (2002) Novel processes for the preparation or (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. US Patent Application US 2002/0151717 (A1).
-
(2002)
-
-
Daugs, E.D.1
Evans, J.C.2
Flemming, H.W.3
Hilpert, T.H.E.4
Koek, J.N.5
-
46
-
-
80053438133
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/1185. Accessed 2011 Jun 27.
-
-
-
-
47
-
-
84926514034
-
Über die reduktion der China-ketone zu China-alkoholen und über die sterische umlagerung von China-alkaloiden. Stereochemische forschungen. II
-
(DOI: 10.1002/jlac.19324920112)
-
Rabe P, (1932) Über die reduktion der China-ketone zu China-alkoholen und über die sterische umlagerung von China-alkaloiden. Stereochemische forschungen. II. Liebigs Ann Chem 492: 242-266 (DOI: 10.1002/jlac.19324920112).
-
(1932)
Liebigs Ann Chem
, vol.492
, pp. 242-266
-
-
Rabe, P.1
-
48
-
-
80053442827
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/1309. Accessed 2011 Jun 27.
-
-
-
-
49
-
-
80053444282
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/1468. Accessed 2011 Jun 27.
-
-
-
-
50
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/333. Accessed 2011 Jun 27.
-
-
-
-
51
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/schisto/community. Accessed 2011 Jun 27.
-
-
-
-
52
-
-
80053458865
-
-
OurExperiment.org website, Available:, (Accessed 2011 Jun 27)
-
OurExperiment.org website. Available: http://www.ourexperiment.org/, (Accessed 2011 Jun 27).
-
-
-
-
53
-
-
80053281919
-
Open Science is a Research Accelerator
-
doi:10.1038/nchem.1149
-
Woelfle M, Olliaro P, Todd MH, (2011) Open Science is a Research Accelerator. Nature Chemistry 3 doi:10.1038/nchem.1149.
-
(2011)
Nature Chemistry
, vol.3
-
-
Woelfle, M.1
Olliaro, P.2
Todd, M.H.3
-
54
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/202. Accessed 2011 Jun 27.
-
-
-
-
56
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/323. Accessed 2011 Jun 27.
-
-
-
-
57
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27. Raw data to date at the OurExperiment.org website. Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/205. Accessed 2011 Jun 27. Raw data to date at the OurExperiment.org website. Available: http://www.ourexperiment.org/racemic_pzq. Accessed 2011 Jun 27.
-
-
-
-
58
-
-
4344713238
-
Highly enantioselective catalytic acyl-Pictet-Spengler reactions
-
(DOI: 10.1021/ja046259p)
-
Taylor MS, Jacobsen EN, (2004) Highly enantioselective catalytic acyl-Pictet-Spengler reactions. J Am Chem Soc 126: 10558-10559 (DOI: 10.1021/ja046259p).
-
(2004)
J Am Chem Soc
, vol.126
, pp. 10558-10559
-
-
Taylor, M.S.1
Jacobsen, E.N.2
-
59
-
-
78249263817
-
Efficient multicomponent reaction synthesis of the schistosomiasis drug praziquantel
-
(DOI: 10.1002/chem.201002046)
-
Cao H, Liu H, Doemling A, (2010) Efficient multicomponent reaction synthesis of the schistosomiasis drug praziquantel. Chem Eur J 16: 12296-12298 (DOI: 10.1002/chem.201002046).
-
(2010)
Chem Eur J
, vol.16
, pp. 12296-12298
-
-
Cao, H.1
Liu, H.2
Doemling, A.3
-
60
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/312. Accessed 2011 Jun 27.
-
-
-
-
61
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/305. Accessed 2011 Jun 27.
-
-
-
-
62
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/313. Accessed 2011 Jun 27.
-
-
-
-
63
-
-
80053446782
-
The Synaptic Leap website
-
Available:. Accessed 2011 Jun 27
-
The Synaptic Leap website. Available: http://www.thesynapticleap.org/node/305#comment-595. Accessed 2011 Jun 27.
-
-
-
-
64
-
-
80053437555
-
-
OurExperiment.org website, Available:. Accessed 2011 Jun 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/racres_pzq/641. Accessed 2011 Jun 27.
-
-
-
-
65
-
-
0042745453
-
Dutch Resolution: Separation of Enantiomers with Families of Resolving Agents. A Status Report
-
(DOI: 10.1055/s-2003-40508)
-
Kellogg RM, Nieuwenhuijzen JW, Pouwer K, Vries TR, Broxterman QB, et al. (2003) Dutch Resolution: Separation of Enantiomers with Families of Resolving Agents. A Status Report. Synthesis pp. 1626-1638 (DOI: 10.1055/s-2003-40508).
-
(2003)
Synthesis
, pp. 1626-1638
-
-
Kellogg, R.M.1
Nieuwenhuijzen, J.W.2
Pouwer, K.3
Vries, T.R.4
Broxterman, Q.B.5
-
66
-
-
0032544370
-
The Family Approach to the Resolution of Racemates
-
(DOI: 10.1002/(SICI)1521-3773(19980918)37:17&2349::AID-ANIE2349>3.0.CO;2-I)
-
Vries T, Wynberg H, van Echten E, Koek J, tenHoeve W, et al. (1998) The Family Approach to the Resolution of Racemates. Angew Chem Int Ed 37: 2349-2354 (DOI: 10.1002/(SICI)1521-3773(19980918)37:17&2349::AID-ANIE2349>3.0.CO;2-I).
-
(1998)
Angew Chem Int Ed
, vol.37
, pp. 2349-2354
-
-
Vries, T.1
Wynberg, H.2
van Echten, E.3
Koek, J.4
Ten Hoeve, W.5
-
67
-
-
0000393537
-
Interactions d'enantiomeres en solution; influence sur le pouvoir rotatoire: Purete optique et purete enantiomerique
-
DOI:10.1016/S0040-4039(01)88364-7)
-
Horeau A, (1969) Interactions d'enantiomeres en solution; influence sur le pouvoir rotatoire: Purete optique et purete enantiomerique. Tetrahedron Lett 10: 3121-3124 DOI:10.1016/S0040-4039(01)88364-7).
-
(1969)
Tetrahedron Lett
, vol.10
, pp. 3121-3124
-
-
Horeau, A.1
-
68
-
-
80053454247
-
-
OurExperiment.org website, Available:. Accessed 2011 June 27
-
OurExperiment.org website. Available: http://www.ourexperiment.org/rac_pza. Accessed 2011 June 27.
-
-
-
-
69
-
-
80053435426
-
-
The OurExperiment.org website, Available:. Accessed 2011 June 27
-
The OurExperiment.org website. Available: http://pzq.ourexperiment.org/. Accessed 2011 June 27.
-
-
-
|