Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells

Journal of Neuroinflammation

Volumn 11, Issue , 2014, Pages

  Song, Suk Young ^a   Jung, Yu Y ^a   Hwang, Chul J ^a   Lee, Hee P ^a   Sok, Chang H ^a   Kim, Joo H ^a   Lee, Sang M ^a   Seo, Hyun O ^a   Hyun, Byung K ^a   Choi, Dong Y ^b   Han, Sang B ^a   Ham, Young W ^c   Hwang, Bang Y ^a   Hong, Jin T ^a  

^a Chungbuk National University   (South Korea)

^b Yeungnam University   (South Korea)

^c Brigham Young University   (United States)

Author keywords

ent Sauchinone; neuroinflammation; nuclear factor kappa B; STAT3

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE; CYCLOOXYGENASE 2; ENT SAUCHINONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; AMYLOID BETA-PROTEIN (1-42); BENZOPYRAN DERIVATIVE; GLIAL FIBRILLARY ACIDIC PROTEIN; PEPTIDE FRAGMENT; SAUCHINONE; STAT3 PROTEIN, RAT;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MICROGLIA; MICROGLIAL CELL CULTURE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; RAT; SAURURACEAE; SAURURUS CHINENSIS; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; GEL MOBILITY SHIFT ASSAY; GENETICS; METABOLISM; NEWBORN; SPRAGUE DAWLEY RAT;

AMYLOID BETA-PEPTIDES; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BENZOPYRANS; CELL SURVIVAL; CELLS, CULTURED; CYCLOOXYGENASE 2; DIOXOLES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GLIAL FIBRILLARY ACIDIC PROTEIN; LIPOPOLYSACCHARIDES; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84904068721     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-118     Document Type: Article

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